Rattus norvegicus

110 known processes

Atic

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Atic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.206
organic acid metabolic process GO:0006082 292 0.095
alpha amino acid metabolic process GO:1901605 71 0.087
rna metabolic process GO:0016070 406 0.084
single organism biosynthetic process GO:0044711 342 0.073
cellular component biogenesis GO:0044085 368 0.067
organophosphate metabolic process GO:0019637 370 0.055
positive regulation of cell proliferation GO:0008284 249 0.053
cellular response to growth factor stimulus GO:0071363 162 0.045
regulation of cell proliferation GO:0042127 359 0.043
protein complex assembly GO:0006461 263 0.043
cellular amino acid metabolic process GO:0006520 107 0.042
cellular component assembly GO:0022607 360 0.042
rna biosynthetic process GO:0032774 380 0.041
apoptotic process GO:0006915 381 0.040
oxoacid metabolic process GO:0043436 290 0.039
single organism catabolic process GO:0044712 283 0.038
gland development GO:0048732 155 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.034
macromolecular complex assembly GO:0065003 273 0.032
response to oxygen levels GO:0070482 265 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
regulation of transcription dna templated GO:0006355 374 0.032
regulation of protein metabolic process GO:0051246 289 0.031
central nervous system development GO:0007417 311 0.031
protein oligomerization GO:0051259 191 0.030
response to growth factor GO:0070848 189 0.030
response to decreased oxygen levels GO:0036293 237 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
regulation of programmed cell death GO:0043067 341 0.029
cellular amino acid biosynthetic process GO:0008652 32 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.028
response to nutrient GO:0007584 248 0.028
programmed cell death GO:0012501 392 0.028
organic acid biosynthetic process GO:0016053 83 0.028
nucleic acid templated transcription GO:0097659 379 0.027
response to nutrient levels GO:0031667 370 0.027
tetrahydrofolate metabolic process GO:0046653 9 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
protein phosphorylation GO:0006468 345 0.027
organic substance catabolic process GO:1901575 316 0.027
response to extracellular stimulus GO:0009991 380 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
regulation of cellular component organization GO:0051128 368 0.026
regulation of rna biosynthetic process GO:2001141 381 0.025
nitrogen compound transport GO:0071705 229 0.025
protein complex biogenesis GO:0070271 263 0.025
transcription dna templated GO:0006351 377 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
neuron differentiation GO:0030182 368 0.024
regulation of response to external stimulus GO:0032101 106 0.024
cellular amine metabolic process GO:0044106 38 0.023
organelle organization GO:0006996 266 0.023
response to hypoxia GO:0001666 231 0.023
single organism reproductive process GO:0044702 297 0.023
tissue development GO:0009888 252 0.023
response to inorganic substance GO:0010035 377 0.022
axis specification GO:0009798 4 0.022
response to glucose GO:0009749 136 0.022
response to lipopolysaccharide GO:0032496 191 0.021
anterior posterior pattern specification GO:0009952 1 0.021
response to hexose GO:0009746 144 0.021
negative regulation of signaling GO:0023057 157 0.021
regulation of nervous system development GO:0051960 264 0.021
catabolic process GO:0009056 351 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of molecular function GO:0065009 398 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
amine metabolic process GO:0009308 38 0.020
neurological system process GO:0050877 219 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
ion transmembrane transport GO:0034220 365 0.019
negative regulation of metabolic process GO:0009892 331 0.019
protein localization GO:0008104 191 0.019
reproduction GO:0000003 245 0.019
regulation of cell differentiation GO:0045595 320 0.018
negative regulation of developmental process GO:0051093 125 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
circulatory system process GO:0003013 183 0.018
macromolecule localization GO:0033036 252 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
protein complex subunit organization GO:0071822 302 0.017
neuron development GO:0048666 286 0.017
locomotion GO:0040011 237 0.017
gliogenesis GO:0042063 93 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
multi organism reproductive process GO:0044703 262 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
anion transport GO:0006820 178 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
cellular catabolic process GO:0044248 295 0.016
intracellular transport GO:0046907 185 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
rhythmic process GO:0048511 156 0.016
cation transport GO:0006812 382 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
reproductive structure development GO:0048608 128 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
reproductive process GO:0022414 372 0.016
developmental process involved in reproduction GO:0003006 159 0.016
response to monosaccharide GO:0034284 159 0.016
ncrna processing GO:0034470 3 0.016
regulation of signal transduction GO:0009966 318 0.015
positive regulation of developmental process GO:0051094 283 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
regeneration GO:0031099 163 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
embryonic pattern specification GO:0009880 1 0.015
glial cell differentiation GO:0010001 65 0.015
neural crest cell development GO:0014032 2 0.015
regulation of apoptotic process GO:0042981 335 0.014
oxidation reduction process GO:0055114 304 0.014
cellular response to stress GO:0033554 269 0.014
response to ketone GO:1901654 182 0.014
cytoplasmic transport GO:0016482 115 0.014
hepaticobiliary system development GO:0061008 90 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
negative regulation of cell communication GO:0010648 158 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
response to peptide hormone GO:0043434 278 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
regulation of phosphorylation GO:0042325 248 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of molecular function GO:0044093 230 0.013
homeostatic process GO:0042592 331 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
cellular homeostasis GO:0019725 252 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
negative regulation of gene expression GO:0010629 199 0.013
regulation of response to stress GO:0080134 126 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
cardiovascular system development GO:0072358 134 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
reproductive system development GO:0061458 128 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of neurogenesis GO:0050767 247 0.013
response to metal ion GO:0010038 253 0.013
response to biotic stimulus GO:0009607 226 0.013
cellular macromolecule localization GO:0070727 122 0.013
protein maturation GO:0051604 68 0.013
epithelium development GO:0060429 96 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
response to peptide GO:1901652 292 0.012
cell morphogenesis GO:0000902 142 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
defense response GO:0006952 194 0.012
neuron projection development GO:0031175 273 0.012
multicellular organism reproduction GO:0032504 233 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
eye morphogenesis GO:0048592 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
nucleotide metabolic process GO:0009117 279 0.012
response to estrogen GO:0043627 232 0.012
regulation of rna metabolic process GO:0051252 391 0.012
blood circulation GO:0008015 183 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
folic acid containing compound metabolic process GO:0006760 10 0.011
small molecule biosynthetic process GO:0044283 124 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein homooligomerization GO:0051260 91 0.011
response to wounding GO:0009611 254 0.011
response to radiation GO:0009314 137 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
response to purine containing compound GO:0014074 126 0.011
eye development GO:0001654 50 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of cell development GO:0060284 263 0.011
cellular component movement GO:0006928 248 0.011
growth GO:0040007 165 0.011
action potential GO:0001508 54 0.011
positive regulation of secretion GO:0051047 140 0.011
cellular ketone metabolic process GO:0042180 51 0.011
heterocycle catabolic process GO:0046700 167 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of cell motility GO:2000145 131 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
immune system process GO:0002376 204 0.011
regulation of membrane potential GO:0042391 110 0.011
translation GO:0006412 35 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cell projection organization GO:0030030 302 0.010
response to light stimulus GO:0009416 52 0.010
regulation of anatomical structure size GO:0090066 135 0.010
protein processing GO:0016485 68 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
embryonic axis specification GO:0000578 1 0.010
cellular component morphogenesis GO:0032989 155 0.010
neuronal action potential GO:0019228 35 0.010
brain development GO:0007420 247 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010
purine containing compound metabolic process GO:0072521 253 0.010
positive regulation of cell death GO:0010942 184 0.010

Atic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
disease of cellular proliferation DOID:14566 0 0.011