Rattus norvegicus

6 known processes

Ptprc

protein tyrosine phosphatase, receptor type, C

(Aliases: CD45,RT7,T200,L-CA,Lca)

Ptprc biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.960
leukocyte activation GO:0045321 76 0.937
Human Mouse
immune system process GO:0002376 204 0.858
Human Mouse
cell activation GO:0001775 97 0.854
Human Mouse
immune response GO:0006955 104 0.802
Human Mouse
response to other organism GO:0051707 220 0.789
Mouse
immune effector process GO:0002252 53 0.711
Mouse
positive regulation of retinal cell programmed cell death GO:0046670 1 0.684
immune response regulating signaling pathway GO:0002764 19 0.684
Human Mouse
response to ionizing radiation GO:0010212 59 0.651
regulation of programmed cell death GO:0043067 341 0.650
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.645
Human Mouse
regulation of leukocyte activation GO:0002694 45 0.632
Human Mouse
regulation of interleukin 1 beta secretion GO:0050706 3 0.632
positive regulation of interleukin 1 secretion GO:0050716 3 0.630
cellular component movement GO:0006928 248 0.610
Human Fly
anatomical structure morphogenesis GO:0009653 298 0.602
Fly
programmed cell death GO:0012501 392 0.590
Mouse
response to gamma radiation GO:0010332 24 0.574
locomotion GO:0040011 237 0.569
Human Fly
neuron projection morphogenesis GO:0048812 122 0.566
Fly
leukocyte activation involved in immune response GO:0002366 16 0.547
Mouse
response to antibiotic GO:0046677 39 0.517
cell motility GO:0048870 202 0.498
Human
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.491
cellular component biogenesis GO:0044085 368 0.478
defense response GO:0006952 194 0.474
Mouse
regulation of protein transport GO:0051223 68 0.461
defense response to other organism GO:0098542 17 0.460
Mouse
regulation of interleukin 1 secretion GO:0050704 3 0.449
response to biotic stimulus GO:0009607 226 0.441
Mouse
response to toxic substance GO:0009636 133 0.392
cellular response to organic cyclic compound GO:0071407 202 0.389
response to external biotic stimulus GO:0043207 221 0.387
Mouse
biological adhesion GO:0022610 110 0.381
Human Mouse
localization of cell GO:0051674 202 0.378
Human
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.375
Fly
macromolecule localization GO:0033036 252 0.371
regulation of mapk cascade GO:0043408 116 0.354
Mouse
t cell proliferation GO:0042098 19 0.350
Mouse
lymphocyte activation GO:0046649 43 0.350
Human Mouse
regulation of immune response GO:0050776 55 0.347
Human Mouse
interleukin 1 beta secretion GO:0050702 3 0.327
single organism cell adhesion GO:0098602 46 0.325
Mouse
calcium ion homeostasis GO:0055074 162 0.318
Mouse
microglial cell activation GO:0001774 14 0.310
positive regulation of cell migration GO:0030335 96 0.309
Human
positive regulation of leukocyte activation GO:0002696 30 0.307
Human Mouse
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.307
response to cytokine GO:0034097 215 0.303
Mouse
positive regulation of response to stimulus GO:0048584 285 0.290
Human Mouse
mononuclear cell proliferation GO:0032943 29 0.289
Human Mouse
apoptotic process GO:0006915 381 0.277
Mouse
motor neuron axon guidance GO:0008045 1 0.276
Fly
response to bacterium GO:0009617 200 0.272
single organism behavior GO:0044708 130 0.268
positive regulation of cell death GO:0010942 184 0.267
Mouse
cellular ion homeostasis GO:0006873 184 0.266
Mouse
regulation of immune system process GO:0002682 123 0.264
Human Mouse
cytoskeleton organization GO:0007010 111 0.261
cell type specific apoptotic process GO:0097285 134 0.256
multicellular organism reproduction GO:0032504 233 0.251
positive regulation of immune system process GO:0002684 90 0.250
Human Mouse
organelle organization GO:0006996 266 0.250
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.250
Mouse
negative regulation of response to stimulus GO:0048585 155 0.247
Mouse Rat
embryonic pattern specification GO:0009880 1 0.234
protein complex subunit organization GO:0071822 302 0.232
positive regulation of cell communication GO:0010647 271 0.231
Mouse
regulation of mononuclear cell proliferation GO:0032944 26 0.227
Human Mouse
regulation of vesicle mediated transport GO:0060627 81 0.224
regulation of phosphate metabolic process GO:0019220 349 0.217
Human Mouse
positive regulation of cell proliferation GO:0008284 249 0.217
Human Mouse
regulation of apoptotic process GO:0042981 335 0.216
Mouse
regulation of lymphocyte migration GO:2000401 1 0.211
axon guidance GO:0007411 24 0.211
Fly
positive regulation of apoptotic process GO:0043065 154 0.205
Mouse
negative regulation of apoptotic process GO:0043066 181 0.203
regulation of signal transduction GO:0009966 318 0.201
Mouse Rat
axonogenesis GO:0007409 71 0.201
Fly
actin filament based process GO:0030029 86 0.198
regulation of organelle organization GO:0033043 80 0.197
single organism organelle organization GO:1902589 180 0.194
cellular component assembly GO:0022607 360 0.187
positive regulation of programmed cell death GO:0043068 157 0.186
Mouse
regulation of locomotion GO:0040012 148 0.185
Human
response to radiation GO:0009314 137 0.185
regulation of neuron apoptotic process GO:0043523 83 0.185
positive regulation of fc receptor mediated stimulatory signaling pathway GO:0060369 1 0.184
positive regulation of cellular biosynthetic process GO:0031328 295 0.183
regulation of secretion GO:0051046 224 0.181
regulation of cellular localization GO:0060341 263 0.180
exocytosis GO:0006887 60 0.179
activation of immune response GO:0002253 26 0.179
Human Mouse
mapk cascade GO:0000165 140 0.178
Mouse
positive regulation of leukocyte proliferation GO:0070665 20 0.178
Human Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.177
Mouse Rat
regulation of retinal cell programmed cell death GO:0046668 1 0.176
single organismal cell cell adhesion GO:0016337 42 0.175
Mouse
gland development GO:0048732 155 0.174
erk1 and erk2 cascade GO:0070371 48 0.174
positive regulation of cell motility GO:2000147 97 0.172
Human
head development GO:0060322 247 0.172
positive regulation of phosphorylation GO:0042327 177 0.172
Mouse
response to lipopolysaccharide GO:0032496 191 0.168
anterior posterior pattern specification GO:0009952 1 0.166
positive regulation of signaling GO:0023056 270 0.163
Mouse
positive regulation of secretion GO:0051047 140 0.163
regulation of cell proliferation GO:0042127 359 0.161
Human Mouse
cellular calcium ion homeostasis GO:0006874 160 0.159
Mouse
cellular homeostasis GO:0019725 252 0.159
Mouse
protein localization GO:0008104 191 0.159
myeloid leukocyte mediated immunity GO:0002444 12 0.159
cognition GO:0050890 92 0.158
positive regulation of molecular function GO:0044093 230 0.156
Mouse
response to wounding GO:0009611 254 0.155
actin filament bundle assembly GO:0051017 19 0.154
cation transport GO:0006812 382 0.153
Mouse
olfactory learning GO:0008355 1 0.152
protein complex biogenesis GO:0070271 263 0.151
response to growth factor GO:0070848 189 0.151
homeostatic process GO:0042592 331 0.151
Mouse
cellular cation homeostasis GO:0030003 180 0.150
Mouse
organ morphogenesis GO:0009887 75 0.149
learning or memory GO:0007611 90 0.149
response to molecule of fungal origin GO:0002238 3 0.149
myeloid leukocyte activation GO:0002274 36 0.148
forebrain development GO:0030900 98 0.147
developmental process involved in reproduction GO:0003006 159 0.147
cell activation involved in immune response GO:0002263 16 0.147
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.147
Mouse
cell migration GO:0016477 197 0.145
Human
regulation of neural precursor cell proliferation GO:2000177 16 0.145
actin filament bundle organization GO:0061572 19 0.145
regulation of molecular function GO:0065009 398 0.144
Human Mouse
wound healing GO:0042060 122 0.144
actin cytoskeleton organization GO:0030036 73 0.144
regulation of cellular protein metabolic process GO:0032268 267 0.141
Human Mouse
secretion by cell GO:0032940 248 0.140
regulation of anatomical structure size GO:0090066 135 0.140
cellular response to growth factor stimulus GO:0071363 162 0.139
blood vessel development GO:0001568 69 0.138
regulation of kinase activity GO:0043549 117 0.138
Human Mouse
negative regulation of cell death GO:0060548 229 0.138
single organism reproductive process GO:0044702 297 0.138
neurotrophin trk receptor signaling pathway GO:0048011 10 0.138
positive regulation of intracellular signal transduction GO:1902533 138 0.138
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 10 0.137
regulation of cell motility GO:2000145 131 0.137
Human
leukocyte chemotaxis GO:0030595 22 0.137
regulation of protein phosphorylation GO:0001932 183 0.135
Human Mouse
t cell activation GO:0042110 29 0.135
Mouse
regulation of map kinase activity GO:0043405 53 0.134
Mouse
neuron death GO:0070997 127 0.134
multicellular organismal reproductive process GO:0048609 233 0.133
regulation of neuron death GO:1901214 115 0.132
regulation of leukocyte migration GO:0002685 24 0.132
protein autophosphorylation GO:0046777 66 0.129
Mouse
protein phosphorylation GO:0006468 345 0.129
Human Mouse
cytokine secretion GO:0050663 15 0.127
leukocyte migration GO:0050900 38 0.127
response to oxygen levels GO:0070482 265 0.126
regulation of secretion by cell GO:1903530 208 0.126
myeloid cell apoptotic process GO:0033028 6 0.122
glial cell apoptotic process GO:0034349 8 0.122
anatomical structure formation involved in morphogenesis GO:0048646 83 0.120
secretion GO:0046903 307 0.119
negative regulation of programmed cell death GO:0043069 183 0.119
regulation of immunoglobulin production GO:0002637 4 0.118
Mouse
cytokine mediated signaling pathway GO:0019221 43 0.118
Mouse
regulation of cellular component movement GO:0051270 150 0.117
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.116
Mouse
myeloid cell activation involved in immune response GO:0002275 13 0.115
protein transport GO:0015031 132 0.115
regulation of cellular ketone metabolic process GO:0010565 27 0.113
sequestering of calcium ion GO:0051208 8 0.113
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.112
intracellular signal transduction GO:0035556 314 0.112
Mouse
regulation of erk1 and erk2 cascade GO:0070372 41 0.112
regulation of myeloid cell differentiation GO:0045637 12 0.111
macromolecular complex assembly GO:0065003 273 0.111
signal transduction by phosphorylation GO:0023014 144 0.111
Mouse
granulocyte chemotaxis GO:0071621 15 0.109
leukocyte degranulation GO:0043299 12 0.109
central nervous system development GO:0007417 311 0.109
Rat
reproductive process GO:0022414 372 0.108
leukocyte proliferation GO:0070661 29 0.107
Human Mouse
neuron differentiation GO:0030182 368 0.107
Fly
cellular metal ion homeostasis GO:0006875 172 0.106
Mouse
regulation of cell migration GO:0030334 128 0.106
Human
response to cobalt ion GO:0032025 12 0.105
positive regulation of transcription factor import into nucleus GO:0042993 4 0.104
cell projection morphogenesis GO:0048858 123 0.104
Fly
mast cell chemotaxis GO:0002551 4 0.104
memory GO:0007613 54 0.104
behavior GO:0007610 205 0.103
regulation of t cell proliferation GO:0042129 17 0.103
Mouse
cell morphogenesis involved in differentiation GO:0000904 119 0.102
Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.102
Mouse
cellular component morphogenesis GO:0032989 155 0.102
Fly
chemotaxis GO:0006935 66 0.102
Fly
positive regulation of cytokine secretion GO:0050715 9 0.102
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.102
Mouse
positive regulation of lymphocyte activation GO:0051251 25 0.102
Human Mouse
catabolic process GO:0009056 351 0.101
cell morphogenesis GO:0000902 142 0.101
Fly
lens development in camera type eye GO:0002088 13 0.101
cellular lipid metabolic process GO:0044255 208 0.100
ribonucleoside triphosphate catabolic process GO:0009203 122 0.100
homeostasis of number of cells GO:0048872 10 0.099
regulation of cell adhesion GO:0030155 52 0.099
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.098
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.097
regulation of cellular component organization GO:0051128 368 0.095
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.095
inflammatory cell apoptotic process GO:0006925 5 0.095
axis specification GO:0009798 4 0.093
positive regulation of phosphate metabolic process GO:0045937 262 0.093
Mouse
cellular ketone metabolic process GO:0042180 51 0.092
cytosolic calcium ion homeostasis GO:0051480 140 0.092
Mouse
myeloid leukocyte differentiation GO:0002573 20 0.091
cellular catabolic process GO:0044248 295 0.091
regulation of transcription dna templated GO:0006355 374 0.091
regulation of calcium ion transport into cytosol GO:0010522 25 0.091
interleukin 1 secretion GO:0050701 3 0.090
regulation of protein metabolic process GO:0051246 289 0.089
Human Mouse
leukocyte homeostasis GO:0001776 7 0.088
reproduction GO:0000003 245 0.087
limbic system development GO:0021761 38 0.086
lymphocyte migration GO:0072676 3 0.086
positive regulation of interleukin 1 beta production GO:0032731 6 0.084
positive regulation of immunoglobulin production GO:0002639 4 0.083
Mouse
protein complex assembly GO:0006461 263 0.083
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.083
Mouse
axon development GO:0061564 96 0.083
Fly
response to oxidative stress GO:0006979 186 0.082
endocytosis GO:0006897 84 0.082
nucleoside phosphate metabolic process GO:0006753 283 0.082
regulation of cell development GO:0060284 263 0.082
Rat
mesoderm development GO:0007498 2 0.082
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.081
activation of protein kinase b activity GO:0032148 3 0.081
regulation of anatomical structure morphogenesis GO:0022603 141 0.079
g protein coupled receptor signaling pathway GO:0007186 242 0.079
glycosyl compound catabolic process GO:1901658 126 0.078
myeloid cell differentiation GO:0030099 22 0.078
response to molecule of bacterial origin GO:0002237 194 0.078
regulation of establishment of protein localization GO:0070201 69 0.078
myeloid cell homeostasis GO:0002262 6 0.077
regulation of cytokine production GO:0001817 56 0.077
cellular response to steroid hormone stimulus GO:0071383 93 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.076
positive regulation of catalytic activity GO:0043085 184 0.076
Mouse
cellular response to lipid GO:0071396 201 0.076
cell cell signaling GO:0007267 335 0.076
Fly
neutrophil homeostasis GO:0001780 4 0.074
signal release GO:0023061 145 0.074
positive regulation of protein kinase activity GO:0045860 73 0.074
Mouse
leukocyte aggregation GO:0070486 1 0.074
regulation of cellular catabolic process GO:0031329 101 0.074
enzyme linked receptor protein signaling pathway GO:0007167 116 0.073
Rat
mast cell migration GO:0097531 4 0.072
positive regulation of nucleic acid templated transcription GO:1903508 197 0.072
t cell migration GO:0072678 2 0.072
urogenital system development GO:0001655 78 0.072
neuron apoptotic process GO:0051402 88 0.072
defense response to virus GO:0051607 9 0.072
Mouse
positive regulation of locomotion GO:0040017 102 0.071
Human
positive regulation of dna metabolic process GO:0051054 39 0.070
Mouse
aromatic compound catabolic process GO:0019439 168 0.070
regulation of transferase activity GO:0051338 123 0.070
Human Mouse
female gonad development GO:0008585 53 0.069
negative regulation of signal transduction GO:0009968 83 0.069
Mouse Rat
brain development GO:0007420 247 0.068
salivary gland morphogenesis GO:0007435 1 0.068
neuron projection guidance GO:0097485 24 0.068
Fly
regulation of homeostatic process GO:0032844 101 0.068
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.067
regulation of t cell activation GO:0050863 23 0.067
Mouse
regulation of lymphocyte activation GO:0051249 34 0.066
Human Mouse
ion homeostasis GO:0050801 212 0.066
Mouse
response to inorganic substance GO:0010035 377 0.065
negative regulation of signaling GO:0023057 157 0.065
Mouse Rat
hematopoietic or lymphoid organ development GO:0048534 36 0.065
Human Mouse
immunoglobulin mediated immune response GO:0016064 4 0.065
Mouse
salivary gland development GO:0007431 3 0.065
response to estradiol GO:0032355 164 0.065
mast cell degranulation GO:0043303 10 0.064
regulation of protein secretion GO:0050708 28 0.064
regulation of cellular component biogenesis GO:0044087 86 0.063
gastrulation GO:0007369 2 0.062
amine metabolic process GO:0009308 38 0.062
single organism intracellular transport GO:1902582 166 0.062
Mouse
positive regulation of lymphocyte proliferation GO:0050671 20 0.062
Human Mouse
regulation of nervous system development GO:0051960 264 0.062
Rat
response to decreased oxygen levels GO:0036293 237 0.061
blood circulation GO:0008015 183 0.061
nitrogen compound transport GO:0071705 229 0.061
regulation of protein localization GO:0032880 81 0.061
multi organism reproductive process GO:0044703 262 0.061
tube development GO:0035295 89 0.060
gamete generation GO:0007276 124 0.060
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.060
Rat
single organism catabolic process GO:0044712 283 0.059
eye morphogenesis GO:0048592 4 0.059
regulation of cell cycle GO:0051726 73 0.059
Mouse
aging GO:0007568 241 0.059
rna metabolic process GO:0016070 406 0.059
positive regulation of protein metabolic process GO:0051247 178 0.059
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.059
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.059
response to corticosteroid GO:0031960 235 0.059
gliogenesis GO:0042063 93 0.059
Rat
cellular response to lipopolysaccharide GO:0071222 55 0.058
vesicle mediated transport GO:0016192 181 0.057
regulation of catalytic activity GO:0050790 304 0.057
Human Mouse
rna biosynthetic process GO:0032774 380 0.057
regulation of neutrophil migration GO:1902622 6 0.057
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.057
tissue development GO:0009888 252 0.056
Human
regulation of hormone levels GO:0010817 187 0.056
response to mechanical stimulus GO:0009612 134 0.056
regulation of apoptotic signaling pathway GO:2001233 13 0.056
Mouse
cytokine production GO:0001816 61 0.055
neurological system process GO:0050877 219 0.055
negative regulation of neutrophil apoptotic process GO:0033030 3 0.054
chemical homeostasis GO:0048878 292 0.054
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.054
metal ion homeostasis GO:0055065 186 0.054
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.054
histamine production involved in inflammatory response GO:0002349 3 0.054
positive regulation of secretion by cell GO:1903532 128 0.053
single organism membrane organization GO:0044802 74 0.053
positive regulation of immune response GO:0050778 42 0.053
Human Mouse
defense response to gram positive bacterium GO:0050830 2 0.052
regulation of interleukin 1 beta production GO:0032651 7 0.052
regulation of smooth muscle contraction GO:0006940 29 0.052
positive regulation of cell adhesion GO:0045785 30 0.052
nucleoside catabolic process GO:0009164 126 0.052
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.051
regulation of rna metabolic process GO:0051252 391 0.051
b cell activation involved in immune response GO:0002312 1 0.051
Mouse
regulation of cell activation GO:0050865 50 0.050
Human Mouse
regulation of lymphocyte proliferation GO:0050670 26 0.050
Human Mouse
cell part morphogenesis GO:0032990 123 0.050
Fly
regeneration GO:0031099 163 0.050
positive regulation of neutrophil chemotaxis GO:0090023 5 0.050
establishment of organelle localization GO:0051656 37 0.050
regulation of response to wounding GO:1903034 69 0.050
cellular response to stress GO:0033554 269 0.049
regulation of protein serine threonine kinase activity GO:0071900 64 0.049
Mouse
cation homeostasis GO:0055080 195 0.049
Mouse
cardiovascular system development GO:0072358 134 0.049
cell cycle GO:0007049 101 0.048
Human Mouse
erythrocyte differentiation GO:0030218 1 0.048
positive regulation of rna metabolic process GO:0051254 203 0.048
protein oligomerization GO:0051259 191 0.048
positive regulation of mapk cascade GO:0043410 92 0.048
Mouse
ribose phosphate metabolic process GO:0019693 235 0.048
transcription dna templated GO:0006351 377 0.047
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.047
regulation of dna metabolic process GO:0051052 60 0.047
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.047
positive regulation of leukocyte chemotaxis GO:0002690 10 0.047
neuron development GO:0048666 286 0.047
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.047
Human Mouse
single organism cellular localization GO:1902580 102 0.046
regulation of phosphorylation GO:0042325 248 0.046
Human Mouse
embryo development GO:0009790 49 0.046
positive regulation of hydrolase activity GO:0051345 86 0.046
hematopoietic progenitor cell differentiation GO:0002244 2 0.046
Human
gland morphogenesis GO:0022612 12 0.046
sequestering of metal ion GO:0051238 9 0.046
Mouse
regulation of b cell mediated immunity GO:0002712 2 0.045
Mouse
actin filament polymerization GO:0030041 11 0.045
interleukin 1 production GO:0032612 11 0.045
cellular response to molecule of fungal origin GO:0071226 1 0.045
regulation of cellular extravasation GO:0002691 2 0.045
cell adhesion GO:0007155 110 0.045
Human Mouse
positive regulation of developmental process GO:0051094 283 0.044
Mouse Rat
positive regulation of protein transport GO:0051222 41 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
reproductive structure development GO:0048608 128 0.044
regulation of lipid metabolic process GO:0019216 68 0.044
cell projection organization GO:0030030 302 0.044
Fly
actin filament organization GO:0007015 42 0.044
positive regulation of protein modification process GO:0031401 142 0.044
Mouse
organic acid metabolic process GO:0006082 292 0.043
cellular response to tumor necrosis factor GO:0071356 46 0.043
regulation of cytoskeleton organization GO:0051493 49 0.043
reproductive system development GO:0061458 128 0.043
cellular response to mechanical stimulus GO:0071260 48 0.043
heterocycle catabolic process GO:0046700 167 0.043
circulatory system process GO:0003013 183 0.043
cellular response to external stimulus GO:0071496 118 0.043
nucleotide catabolic process GO:0009166 139 0.043
lymphocyte proliferation GO:0046651 29 0.043
Human Mouse
regulation of ion transport GO:0043269 245 0.043
protein heterooligomerization GO:0051291 89 0.042
positive regulation of neuron apoptotic process GO:0043525 33 0.042
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 5 0.042
intracellular transport GO:0046907 185 0.042
Mouse
positive regulation of humoral immune response GO:0002922 2 0.041
Mouse
embryonic axis specification GO:0000578 1 0.041
sexual reproduction GO:0019953 148 0.041
response to dexamethasone GO:0071548 49 0.041
tissue regeneration GO:0042246 36 0.041
response to hypoxia GO:0001666 231 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.041
apoptotic signaling pathway GO:0097190 27 0.040
Mouse
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 1 0.040
negative regulation of molecular function GO:0044092 133 0.040
Human Mouse
regulation of response to stress GO:0080134 126 0.040
telencephalon development GO:0021537 62 0.040
negative regulation of gene expression GO:0010629 199 0.039
platelet aggregation GO:0070527 4 0.039
regulation of actin filament based process GO:0032970 42 0.039
dna metabolic process GO:0006259 96 0.039
Mouse
smooth muscle cell migration GO:0014909 36 0.039
ribonucleotide catabolic process GO:0009261 136 0.039
retinal cell programmed cell death GO:0046666 1 0.039
positive regulation of transferase activity GO:0051347 81 0.039
Mouse
digestive system development GO:0055123 41 0.039
cellular response to nitrogen compound GO:1901699 210 0.038
Rat
divalent metal ion transport GO:0070838 132 0.038
Mouse
regulation of lymphocyte chemotaxis GO:1901623 1 0.038
positive regulation of neurogenesis GO:0050769 165 0.038
Rat
positive regulation of cell differentiation GO:0045597 217 0.038
Mouse Rat
negative regulation of metabolic process GO:0009892 331 0.038
Human Mouse
leukocyte mediated immunity GO:0002443 28 0.038
Mouse
mitotic cell cycle GO:0000278 49 0.038
small gtpase mediated signal transduction GO:0007264 36 0.038
developmental growth GO:0048589 100 0.038
regulation of leukocyte proliferation GO:0070663 26 0.037
Human Mouse
positive regulation of cytoskeleton organization GO:0051495 26 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
positive regulation of leukocyte degranulation GO:0043302 4 0.037
response to carbohydrate GO:0009743 183 0.037
immune response activating signal transduction GO:0002757 15 0.037
Human Mouse
positive regulation of lipid kinase activity GO:0090218 2 0.037
response to reactive oxygen species GO:0000302 120 0.037
cellular response to abiotic stimulus GO:0071214 85 0.037
regulation of b cell differentiation GO:0045577 1 0.036
Mouse
syncytium formation by plasma membrane fusion GO:0000768 3 0.036
peptidyl amino acid modification GO:0018193 126 0.036
Mouse
regulation of exocytosis GO:0017157 37 0.036
cellular response to ketone GO:1901655 51 0.035
positive regulation of cellular amine metabolic process GO:0033240 3 0.035
regulation of cellular component size GO:0032535 51 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
peptidyl tyrosine modification GO:0018212 72 0.035
Mouse
regulation of smooth muscle cell proliferation GO:0048660 75 0.035
histamine secretion involved in inflammatory response GO:0002441 3 0.035
nucleic acid templated transcription GO:0097659 379 0.034
regulation of catabolic process GO:0009894 113 0.034
purine containing compound metabolic process GO:0072521 253 0.034
organelle localization GO:0051640 55 0.034
regulation of cytokine secretion GO:0050707 11 0.034
regulation of protein kinase activity GO:0045859 105 0.034
Human Mouse
response to extracellular stimulus GO:0009991 380 0.034
response to alkaloid GO:0043279 132 0.034
circulatory system development GO:0072359 134 0.033
positive regulation of mononuclear cell proliferation GO:0032946 20 0.033
Human Mouse
peptide biosynthetic process GO:0043043 3 0.033
regulation of hydrolase activity GO:0051336 143 0.033
regulation of neuron differentiation GO:0045664 208 0.033
heterotypic cell cell adhesion GO:0034113 2 0.033
Mouse
regulation of chemotaxis GO:0050920 29 0.033
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.033
negative regulation of homeostatic process GO:0032845 47 0.032
Mouse
actin polymerization or depolymerization GO:0008154 14 0.032
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.032
metal ion transport GO:0030001 289 0.032
Mouse
oxoacid metabolic process GO:0043436 290 0.032
positive regulation of map kinase activity GO:0043406 46 0.032
Mouse
negative regulation of growth GO:0045926 37 0.032
hormone transport GO:0009914 121 0.032
reactive oxygen species metabolic process GO:0072593 37 0.032
hormone secretion GO:0046879 115 0.032
chemosensory behavior GO:0007635 2 0.032
immune system development GO:0002520 41 0.031
Human Mouse
cellular response to oxygen containing compound GO:1901701 386 0.031
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.031
Mouse
peptidyl tyrosine phosphorylation GO:0018108 72 0.031
Mouse
nucleoside metabolic process GO:0009116 179 0.031
negative regulation of cell communication GO:0010648 158 0.031
Mouse Rat
response to heat GO:0009408 60 0.030
muscle system process GO:0003012 115 0.030
positive regulation of neutrophil migration GO:1902624 6 0.030
regulation of cell growth GO:0001558 85 0.030
epidermal growth factor receptor signaling pathway GO:0007173 23 0.029
membrane organization GO:0061024 94 0.029
positive regulation of neuron death GO:1901216 43 0.029
cellular nitrogen compound catabolic process GO:0044270 163 0.029
metanephric tubule morphogenesis GO:0072173 2 0.029

Ptprc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org