Rattus norvegicus

61 known processes

Ptpra

protein tyrosine phosphatase, receptor type, A

(Aliases: LRP,MGC93561)

Ptpra biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of catalytic activity GO:0050790 304 0.085
Zebrafish
rna biosynthetic process GO:0032774 380 0.078
regulation of rna metabolic process GO:0051252 391 0.076
rna metabolic process GO:0016070 406 0.076
regulation of cellular component organization GO:0051128 368 0.075
regulation of nucleic acid templated transcription GO:1903506 380 0.073
cation transport GO:0006812 382 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.068
Zebrafish
transcription dna templated GO:0006351 377 0.059
catabolic process GO:0009056 351 0.059
carboxylic acid metabolic process GO:0019752 289 0.058
oxoacid metabolic process GO:0043436 290 0.056
regulation of rna biosynthetic process GO:2001141 381 0.055
organophosphate metabolic process GO:0019637 370 0.051
positive regulation of rna biosynthetic process GO:1902680 197 0.049
regulation of phosphate metabolic process GO:0019220 349 0.049
Zebrafish
regulation of transcription dna templated GO:0006355 374 0.048
neuron projection development GO:0031175 273 0.047
Fly
organelle organization GO:0006996 266 0.046
regulation of multicellular organismal development GO:2000026 376 0.045
nucleic acid templated transcription GO:0097659 379 0.045
reproductive process GO:0022414 372 0.045
regulation of molecular function GO:0065009 398 0.044
Zebrafish
anatomical structure morphogenesis GO:0009653 298 0.044
Zebrafish Fly
cellular cation homeostasis GO:0030003 180 0.044
regulation of ion transport GO:0043269 245 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.042
homeostatic process GO:0042592 331 0.041
cellular ion homeostasis GO:0006873 184 0.041
nucleotide metabolic process GO:0009117 279 0.040
programmed cell death GO:0012501 392 0.039
cellular nitrogen compound catabolic process GO:0044270 163 0.039
organic acid metabolic process GO:0006082 292 0.039
response to nutrient levels GO:0031667 370 0.038
response to extracellular stimulus GO:0009991 380 0.038
central nervous system development GO:0007417 311 0.038
amine metabolic process GO:0009308 38 0.038
cellular amino acid metabolic process GO:0006520 107 0.037
organic substance catabolic process GO:1901575 316 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
purine nucleotide metabolic process GO:0006163 229 0.037
regulation of apoptotic process GO:0042981 335 0.036
cellular chemical homeostasis GO:0055082 247 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.036
ribonucleotide metabolic process GO:0009259 231 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
neuron differentiation GO:0030182 368 0.035
Fly
purine containing compound metabolic process GO:0072521 253 0.035
neuron development GO:0048666 286 0.035
Fly
chemical homeostasis GO:0048878 292 0.035
cytosolic calcium ion homeostasis GO:0051480 140 0.034
cell projection organization GO:0030030 302 0.034
Fly
regulation of programmed cell death GO:0043067 341 0.034
regulation of cell differentiation GO:0045595 320 0.034
positive regulation of cell differentiation GO:0045597 217 0.034
positive regulation of molecular function GO:0044093 230 0.034
intracellular signal transduction GO:0035556 314 0.034
regulation of signal transduction GO:0009966 318 0.033
Rat
metal ion homeostasis GO:0055065 186 0.033
single organism organelle organization GO:1902589 180 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
ras protein signal transduction GO:0007265 29 0.033
regulation of cell proliferation GO:0042127 359 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
brain development GO:0007420 247 0.033
cellular homeostasis GO:0019725 252 0.032
purine nucleotide catabolic process GO:0006195 136 0.032
ribose phosphate metabolic process GO:0019693 235 0.031
reproduction GO:0000003 245 0.031
apoptotic process GO:0006915 381 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
single organism catabolic process GO:0044712 283 0.030
nucleoside phosphate catabolic process GO:1901292 140 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
cellular component biogenesis GO:0044085 368 0.030
ion transmembrane transport GO:0034220 365 0.030
cellular catabolic process GO:0044248 295 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
guanosine containing compound catabolic process GO:1901069 71 0.029
ion homeostasis GO:0050801 212 0.029
positive regulation of developmental process GO:0051094 283 0.029
regulation of nervous system development GO:0051960 264 0.029
purine nucleoside triphosphate metabolic process GO:0009144 141 0.029
ribonucleoside metabolic process GO:0009119 174 0.029
cellular component assembly GO:0022607 360 0.029
response to hypoxia GO:0001666 231 0.029
nucleoside catabolic process GO:0009164 126 0.029
positive regulation of transcription dna templated GO:0045893 197 0.028
response to oxygen levels GO:0070482 265 0.028
positive regulation of gene expression GO:0010628 244 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
calcium ion transport GO:0006816 131 0.028
cellular amine metabolic process GO:0044106 38 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
cellular calcium ion homeostasis GO:0006874 160 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
nucleoside metabolic process GO:0009116 179 0.028
divalent metal ion transport GO:0070838 132 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
calcium ion homeostasis GO:0055074 162 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.027
single organism biosynthetic process GO:0044711 342 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
positive regulation of transport GO:0051050 245 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
response to peptide GO:1901652 292 0.027
Mouse Rat
vesicle mediated transport GO:0016192 181 0.027
small gtpase mediated signal transduction GO:0007264 36 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
transmembrane transport GO:0055085 412 0.026
protein phosphorylation GO:0006468 345 0.026
Zebrafish Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
ribonucleotide catabolic process GO:0009261 136 0.026
multi organism reproductive process GO:0044703 262 0.026
regulation of cell projection organization GO:0031344 175 0.026
cation homeostasis GO:0055080 195 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
Fly
cellular component movement GO:0006928 248 0.025
Fly
cellular response to stress GO:0033554 269 0.025
divalent inorganic cation transport GO:0072511 134 0.025
regulation of nucleotide metabolic process GO:0006140 117 0.025
cellular metal ion homeostasis GO:0006875 172 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
heterocycle catabolic process GO:0046700 167 0.024
organophosphate catabolic process GO:0046434 148 0.024
response to decreased oxygen levels GO:0036293 237 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
Mouse Rat
metal ion transport GO:0030001 289 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
multicellular organism reproduction GO:0032504 233 0.024
purine nucleoside triphosphate catabolic process GO:0009146 122 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
actin cytoskeleton organization GO:0030036 73 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
purine containing compound catabolic process GO:0072523 138 0.023
macromolecule localization GO:0033036 252 0.023
negative regulation of metabolic process GO:0009892 331 0.023
response to growth factor GO:0070848 189 0.023
cell part morphogenesis GO:0032990 123 0.023
Fly
cellular response to growth factor stimulus GO:0071363 162 0.023
cation transmembrane transport GO:0098655 263 0.023
lipid metabolic process GO:0006629 283 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
regulation of cell development GO:0060284 263 0.022
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
regulation of metal ion transport GO:0010959 118 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
negative regulation of developmental process GO:0051093 125 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
regulation of cellular localization GO:0060341 263 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
negative regulation of nervous system development GO:0051961 79 0.022
chemotaxis GO:0006935 66 0.021
Fly
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
single organism intracellular transport GO:1902582 166 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
endocytosis GO:0006897 84 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
gland development GO:0048732 155 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
growth GO:0040007 165 0.021
neurological system process GO:0050877 219 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
negative regulation of transport GO:0051051 136 0.021
negative regulation of cell death GO:0060548 229 0.021
multicellular organism growth GO:0035264 1 0.021
locomotion GO:0040011 237 0.021
Fly
cytoskeleton organization GO:0007010 111 0.021
regulation of phosphorylation GO:0042325 248 0.021
Zebrafish
cellular component morphogenesis GO:0032989 155 0.021
Fly
positive regulation of nervous system development GO:0051962 178 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
immune system process GO:0002376 204 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
cell cell signaling GO:0007267 335 0.020
Fly
chromosome segregation GO:0007059 2 0.020
response to metal ion GO:0010038 253 0.020
response to corticosteroid GO:0031960 235 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of signal transduction GO:0009967 175 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
Mouse Rat
tissue development GO:0009888 252 0.020
Zebrafish
guanosine containing compound metabolic process GO:1901068 74 0.020
regulation of protein phosphorylation GO:0001932 183 0.019
Zebrafish
cardiovascular system development GO:0072358 134 0.019
protein complex biogenesis GO:0070271 263 0.019
regulation of purine nucleotide catabolic process GO:0033121 65 0.019
secretion by cell GO:0032940 248 0.019
defense response GO:0006952 194 0.019
response to peptide hormone GO:0043434 278 0.019
Mouse Rat
positive regulation of signaling GO:0023056 270 0.019
regulation of neuron differentiation GO:0045664 208 0.019
neuron projection morphogenesis GO:0048812 122 0.019
Fly
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
cellular lipid metabolic process GO:0044255 208 0.018
cell morphogenesis GO:0000902 142 0.018
Fly
purine nucleoside metabolic process GO:0042278 169 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
carbohydrate metabolic process GO:0005975 130 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
gtp catabolic process GO:0006184 71 0.018
cell motility GO:0048870 202 0.018
regulation of neuron projection development GO:0010975 161 0.018
sexual reproduction GO:0019953 148 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
intracellular transport GO:0046907 185 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
cell type specific apoptotic process GO:0097285 134 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of nucleoside metabolic process GO:0009118 66 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
cell migration GO:0016477 197 0.017
positive regulation of cell death GO:0010942 184 0.017
response to ethanol GO:0045471 162 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
cell cycle GO:0007049 101 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
circulatory system development GO:0072359 134 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
cellular response to hormone stimulus GO:0032870 247 0.016
Mouse Rat
regulation of kinase activity GO:0043549 117 0.016
Zebrafish
regulation of calcium ion transport GO:0051924 77 0.016
response to inorganic substance GO:0010035 377 0.016
single organism reproductive process GO:0044702 297 0.016
regulation of catabolic process GO:0009894 113 0.016
aging GO:0007568 241 0.016
secretion GO:0046903 307 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
head development GO:0060322 247 0.016
regulation of organelle organization GO:0033043 80 0.016
positive regulation of cell development GO:0010720 176 0.016
phospholipid metabolic process GO:0006644 61 0.016
response to nutrient GO:0007584 248 0.016
protein complex subunit organization GO:0071822 302 0.016
oxidation reduction process GO:0055114 304 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
peptidyl amino acid modification GO:0018193 126 0.015
regulation of mapk cascade GO:0043408 116 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
negative regulation of signaling GO:0023057 157 0.015
Rat
protein localization GO:0008104 191 0.015
negative regulation of molecular function GO:0044092 133 0.015
regulation of hydrolase activity GO:0051336 143 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
cell projection morphogenesis GO:0048858 123 0.015
Fly
response to estrogen GO:0043627 232 0.015
regulation of membrane potential GO:0042391 110 0.015
proteolysis GO:0006508 175 0.015
response to carbohydrate GO:0009743 183 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
positive regulation of protein modification process GO:0031401 142 0.015
response to glucocorticoid GO:0051384 223 0.015
sensory perception GO:0007600 101 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
aromatic compound catabolic process GO:0019439 168 0.014
negative regulation of cell communication GO:0010648 158 0.014
Rat
cellular response to organonitrogen compound GO:0071417 197 0.014
Mouse Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of protein metabolic process GO:0051246 289 0.014
Zebrafish
regulation of gtpase activity GO:0043087 57 0.014
axonogenesis GO:0007409 71 0.014
Fly
organelle localization GO:0051640 55 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
positive regulation of cell communication GO:0010647 271 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
regulation of secretion GO:0051046 224 0.014
response to wounding GO:0009611 254 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of growth GO:0040008 105 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of protein modification process GO:0031399 194 0.014
Zebrafish
negative regulation of programmed cell death GO:0043069 183 0.014
immune response GO:0006955 104 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
synaptic transmission GO:0007268 235 0.013
nitrogen compound transport GO:0071705 229 0.013
regulation of protein kinase activity GO:0045859 105 0.013
Zebrafish
negative regulation of cell proliferation GO:0008285 119 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
gastrulation GO:0007369 2 0.013
Zebrafish
cell adhesion GO:0007155 110 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
glycerolipid metabolic process GO:0046486 67 0.013
protein autophosphorylation GO:0046777 66 0.013
response to ketone GO:1901654 182 0.013
multicellular organismal signaling GO:0035637 44 0.013
sex differentiation GO:0007548 113 0.013
cytoplasmic transport GO:0016482 115 0.013
adult locomotory behavior GO:0008344 4 0.013
localization of cell GO:0051674 202 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
developmental process involved in reproduction GO:0003006 159 0.013
gtp metabolic process GO:0046039 72 0.012
response to cytokine GO:0034097 215 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
spindle organization GO:0007051 2 0.012
protein oligomerization GO:0051259 191 0.012
forebrain development GO:0030900 98 0.012
regulation of cell migration GO:0030334 128 0.012
multi multicellular organism process GO:0044706 138 0.012
establishment of organelle localization GO:0051656 37 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of transferase activity GO:0051338 123 0.012
Zebrafish
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
Zebrafish
dephosphorylation GO:0016311 98 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of transferase activity GO:0051347 81 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to ammonium ion GO:0060359 71 0.012
anion transport GO:0006820 178 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
action potential GO:0001508 54 0.011
regulation of locomotion GO:0040012 148 0.011
axis specification GO:0009798 4 0.011
transmission of nerve impulse GO:0019226 42 0.011
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
neuronal action potential GO:0019228 35 0.011
nucleotide catabolic process GO:0009166 139 0.011
asymmetric protein localization GO:0008105 2 0.011
response to amino acid GO:0043200 75 0.011
regulation of transporter activity GO:0032409 50 0.011
reproductive system development GO:0061458 128 0.011
response to biotic stimulus GO:0009607 226 0.011
axon development GO:0061564 96 0.011
Fly
regeneration GO:0031099 163 0.011
cellular protein localization GO:0034613 122 0.011
atp catabolic process GO:0006200 54 0.011
response to alkaloid GO:0043279 132 0.011
actin filament based process GO:0030029 86 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of hormone levels GO:0010817 187 0.011
cell growth GO:0016049 104 0.011
positive regulation of immune system process GO:0002684 90 0.011
cellular response to external stimulus GO:0071496 118 0.011
response to bacterium GO:0009617 200 0.011
regulation of transmembrane transport GO:0034762 122 0.010
developmental growth GO:0048589 100 0.010
lipid storage GO:0019915 1 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
protein complex assembly GO:0006461 263 0.010
dna metabolic process GO:0006259 96 0.010
rho protein signal transduction GO:0007266 11 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
eye morphogenesis GO:0048592 4 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
Mouse Rat
cellular response to insulin stimulus GO:0032869 81 0.010
Mouse Rat
negative regulation of biosynthetic process GO:0009890 168 0.010
regulation of endocytosis GO:0030100 42 0.010
regulation of cell motility GO:2000145 131 0.010
rhythmic process GO:0048511 156 0.010
maintenance of location GO:0051235 17 0.010
monovalent inorganic cation transport GO:0015672 172 0.010

Ptpra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.013
central nervous system disease DOID:331 0 0.013
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.010