Rattus norvegicus

40 known processes

Ptprn

protein tyrosine phosphatase, receptor type, N

(Aliases: ICA512,Ia-2)

Ptprn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.156
Rat
behavior GO:0007610 205 0.117
oxoacid metabolic process GO:0043436 290 0.110
carboxylic acid metabolic process GO:0019752 289 0.109
nucleobase containing small molecule metabolic process GO:0055086 316 0.103
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.098
regulation of phosphorus metabolic process GO:0051174 349 0.097
Rat
organic acid metabolic process GO:0006082 292 0.094
response to metal ion GO:0010038 253 0.091
regulation of cell development GO:0060284 263 0.082
purine nucleotide metabolic process GO:0006163 229 0.078
Rat
regulation of cellular component organization GO:0051128 368 0.064
response to wounding GO:0009611 254 0.056
purine containing compound metabolic process GO:0072521 253 0.055
Rat
regulation of signal transduction GO:0009966 318 0.054
negative regulation of cell death GO:0060548 229 0.053
regulation of catalytic activity GO:0050790 304 0.053
Rat
neuron differentiation GO:0030182 368 0.050
regulation of intracellular signal transduction GO:1902531 218 0.048
cellular response to organic cyclic compound GO:0071407 202 0.046
response to peptide GO:1901652 292 0.045
single organism biosynthetic process GO:0044711 342 0.045
circulatory system process GO:0003013 183 0.044
ribose phosphate metabolic process GO:0019693 235 0.043
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.043
Rat
single organism catabolic process GO:0044712 283 0.043
Rat
central nervous system development GO:0007417 311 0.043
protein complex assembly GO:0006461 263 0.041
purine nucleotide biosynthetic process GO:0006164 83 0.041
positive regulation of molecular function GO:0044093 230 0.041
purine ribonucleotide metabolic process GO:0009150 227 0.039
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.038
regulation of ion transport GO:0043269 245 0.038
reproduction GO:0000003 245 0.037
cellular component biogenesis GO:0044085 368 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of apoptotic process GO:0042981 335 0.037
response to nutrient GO:0007584 248 0.036
regulation of molecular function GO:0065009 398 0.036
Rat
programmed cell death GO:0012501 392 0.036
cell cell signaling GO:0007267 335 0.036
growth GO:0040007 165 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
Rat
positive regulation of transport GO:0051050 245 0.036
transcription dna templated GO:0006351 377 0.035
lipid metabolic process GO:0006629 283 0.035
synapse organization GO:0050808 46 0.035
positive regulation of response to stimulus GO:0048584 285 0.034
protein complex biogenesis GO:0070271 263 0.034
neurotrophin production GO:0032898 2 0.033
catabolic process GO:0009056 351 0.033
Rat
cellular catabolic process GO:0044248 295 0.033
Rat
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of neuron projection development GO:0010975 161 0.032
macromolecule localization GO:0033036 252 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
negative regulation of programmed cell death GO:0043069 183 0.031
regeneration GO:0031099 163 0.031
macromolecular complex assembly GO:0065003 273 0.030
positive regulation of cell death GO:0010942 184 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
Rat
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
cell migration GO:0016477 197 0.030
organophosphate biosynthetic process GO:0090407 143 0.029
cellular response to organonitrogen compound GO:0071417 197 0.029
ribose phosphate biosynthetic process GO:0046390 87 0.029
response to glucocorticoid GO:0051384 223 0.029
nucleotide metabolic process GO:0009117 279 0.029
Rat
proteolysis GO:0006508 175 0.029
organic substance catabolic process GO:1901575 316 0.029
Rat
intracellular signal transduction GO:0035556 314 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.028
Rat
negative regulation of apoptotic process GO:0043066 181 0.028
cellular response to nitrogen compound GO:1901699 210 0.027
carboxylic acid biosynthetic process GO:0046394 83 0.027
response to vitamin GO:0033273 131 0.027
negative regulation of metabolic process GO:0009892 331 0.027
Rat
response to nutrient levels GO:0031667 370 0.026
blood circulation GO:0008015 183 0.026
negative regulation of phosphorus metabolic process GO:0010563 80 0.026
Rat
response to corticosteroid GO:0031960 235 0.026
nucleic acid templated transcription GO:0097659 379 0.026
negative regulation of phosphate metabolic process GO:0045936 80 0.026
Rat
brain development GO:0007420 247 0.026
immune system process GO:0002376 204 0.026
response to estrogen GO:0043627 232 0.025
regulation of neurotransmitter levels GO:0001505 42 0.025
regulation of rna metabolic process GO:0051252 391 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
Rat
ribonucleotide biosynthetic process GO:0009260 85 0.024
organophosphate metabolic process GO:0019637 370 0.024
Rat
regulation of locomotion GO:0040012 148 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
small molecule biosynthetic process GO:0044283 124 0.023
camp metabolic process GO:0046058 63 0.023
purine containing compound biosynthetic process GO:0072522 85 0.023
chemical homeostasis GO:0048878 292 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
cell morphogenesis GO:0000902 142 0.023
apoptotic process GO:0006915 381 0.023
single organism reproductive process GO:0044702 297 0.023
response to extracellular stimulus GO:0009991 380 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
protein complex subunit organization GO:0071822 302 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
synaptic transmission GO:0007268 235 0.022
regulation of cell differentiation GO:0045595 320 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
Rat
cellular lipid metabolic process GO:0044255 208 0.022
organic acid biosynthetic process GO:0016053 83 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
Rat
cell projection organization GO:0030030 302 0.021
vesicle mediated transport GO:0016192 181 0.021
response to purine containing compound GO:0014074 126 0.021
nucleotide biosynthetic process GO:0009165 98 0.021
axon development GO:0061564 96 0.021
cyclic purine nucleotide metabolic process GO:0052652 62 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
dephosphorylation GO:0016311 98 0.021
gtp catabolic process GO:0006184 71 0.021
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.021
hormone transport GO:0009914 121 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
negative regulation of developmental process GO:0051093 125 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
Rat
cellular component assembly GO:0022607 360 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
Rat
single organism intracellular transport GO:1902582 166 0.020
reproductive process GO:0022414 372 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
organic anion transport GO:0015711 132 0.020
heterocycle catabolic process GO:0046700 167 0.019
Rat
multi organism reproductive process GO:0044703 262 0.019
response to ketone GO:1901654 182 0.019
single organism organelle organization GO:1902589 180 0.019
cellular amine metabolic process GO:0044106 38 0.019
metal ion transport GO:0030001 289 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
cellular ketone metabolic process GO:0042180 51 0.019
protein localization GO:0008104 191 0.019
monocarboxylic acid transport GO:0015718 52 0.019
axonogenesis GO:0007409 71 0.019
cellular component movement GO:0006928 248 0.019
protein transport GO:0015031 132 0.019
gland development GO:0048732 155 0.019
positive regulation of hydrolase activity GO:0051345 86 0.019
localization of cell GO:0051674 202 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
homeostatic process GO:0042592 331 0.018
regulation of peptide transport GO:0090087 87 0.018
positive regulation of cell communication GO:0010647 271 0.018
cellular response to peptide GO:1901653 133 0.018
head development GO:0060322 247 0.018
intracellular transport GO:0046907 185 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
Rat
positive regulation of gene expression GO:0010628 244 0.018
response to bacterium GO:0009617 200 0.018
neuron projection development GO:0031175 273 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
negative regulation of transport GO:0051051 136 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of transcription dna templated GO:0006355 374 0.017
adult locomotory behavior GO:0008344 4 0.017
regulation of phosphorylation GO:0042325 248 0.017
regulation of axonogenesis GO:0050770 37 0.017
multicellular organism reproduction GO:0032504 233 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
sexual reproduction GO:0019953 148 0.017
response to cytokine GO:0034097 215 0.017
transmembrane transport GO:0055085 412 0.017
protein oligomerization GO:0051259 191 0.017
wound healing GO:0042060 122 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to alkaloid GO:0043279 132 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
Rat
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of map kinase activity GO:0043405 53 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of protein metabolic process GO:0051246 289 0.017
regulation of metal ion transport GO:0010959 118 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
Rat
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
regulation of cell motility GO:2000145 131 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
heart morphogenesis GO:0003007 3 0.016
chemosensory behavior GO:0007635 2 0.016
cell projection morphogenesis GO:0048858 123 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
response to peptide hormone GO:0043434 278 0.016
amine metabolic process GO:0009308 38 0.016
neurotransmitter transport GO:0006836 42 0.016
response to toxic substance GO:0009636 133 0.016
lipid localization GO:0010876 62 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.015
response to inorganic substance GO:0010035 377 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
response to insulin GO:0032868 133 0.015
neuron development GO:0048666 286 0.015
endocytosis GO:0006897 84 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of nervous system development GO:0051960 264 0.015
regulation of synaptic transmission GO:0050804 141 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
response to glucose GO:0009749 136 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
neuron death GO:0070997 127 0.015
nucleotide catabolic process GO:0009166 139 0.015
Rat
cell part morphogenesis GO:0032990 123 0.015
regulation of cellular component movement GO:0051270 150 0.014
regulation of cell proliferation GO:0042127 359 0.014
response to estradiol GO:0032355 164 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
Rat
response to acid chemical GO:0001101 222 0.014
aging GO:0007568 241 0.014
regulation of protein modification process GO:0031399 194 0.014
rna metabolic process GO:0016070 406 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
axis specification GO:0009798 4 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of neuron death GO:1901214 115 0.014
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.014
response to hypoxia GO:0001666 231 0.014
cognition GO:0050890 92 0.014
response to radiation GO:0009314 137 0.014
embryonic pattern specification GO:0009880 1 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
rhythmic process GO:0048511 156 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
cellular response to stress GO:0033554 269 0.013
negative regulation of molecular function GO:0044092 133 0.013
Rat
olfactory learning GO:0008355 1 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
regulation of kinase activity GO:0043549 117 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Rat
negative regulation of biosynthetic process GO:0009890 168 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of gtp catabolic process GO:0033124 58 0.013
Rat
response to oxygen levels GO:0070482 265 0.013
cellular homeostasis GO:0019725 252 0.013
regulation of response to stress GO:0080134 126 0.013
response to amine GO:0014075 46 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
Rat
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of transferase activity GO:0051338 123 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of body fluid levels GO:0050878 90 0.013
response to lipopolysaccharide GO:0032496 191 0.013
cellular response to alcohol GO:0097306 87 0.013
regulation of organelle organization GO:0033043 80 0.013
cellular amino acid biosynthetic process GO:0008652 32 0.013
cell motility GO:0048870 202 0.012
response to carbohydrate GO:0009743 183 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
ion transmembrane transport GO:0034220 365 0.012
prepulse inhibition GO:0060134 1 0.012
negative regulation of signaling GO:0023057 157 0.012
gamete generation GO:0007276 124 0.012
amino acid transport GO:0006865 70 0.012
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
organic acid transport GO:0015849 116 0.012
regulation of hydrolase activity GO:0051336 143 0.012
Rat
response to axon injury GO:0048678 59 0.012
developmental growth GO:0048589 100 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
response to camp GO:0051591 91 0.012
cell growth GO:0016049 104 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
cation transmembrane transport GO:0098655 263 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of anatomical structure size GO:0090066 135 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
response to monosaccharide GO:0034284 159 0.011
membrane organization GO:0061024 94 0.011
response to biotic stimulus GO:0009607 226 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
positive regulation of signal transduction GO:0009967 175 0.011
ion homeostasis GO:0050801 212 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
Rat
negative regulation of cell communication GO:0010648 158 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
positive regulation of developmental process GO:0051094 283 0.011
amide transport GO:0042886 105 0.011
regulation of peptidase activity GO:0052547 55 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of nervous system development GO:0051962 178 0.011
single organism behavior GO:0044708 130 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
Rat
regulation of synapse organization GO:0050807 19 0.011
regulation of catabolic process GO:0009894 113 0.011
Rat
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
Rat
negative regulation of response to stimulus GO:0048585 155 0.011
olfactory behavior GO:0042048 2 0.011
peptide transport GO:0015833 97 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
Rat
regulation of homeostatic process GO:0032844 101 0.011
schwann cell migration GO:0036135 2 0.011
response to amino acid GO:0043200 75 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
Rat
acute inflammatory response GO:0002526 58 0.011
secretion GO:0046903 307 0.011
locomotion GO:0040011 237 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
regulation of transmembrane transport GO:0034762 122 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
Rat
regulation of protein phosphorylation GO:0001932 183 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
regulation of gtpase activity GO:0043087 57 0.010
Rat
regulation of peptide hormone secretion GO:0090276 80 0.010
neurotransmitter uptake GO:0001504 3 0.010
response to ethanol GO:0045471 162 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
Rat
response to molecule of bacterial origin GO:0002237 194 0.010
male gamete generation GO:0048232 99 0.010

Ptprn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.026
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.017