Rattus norvegicus

27 known processes

Slc3a2

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

(Aliases: Mdu1)

Slc3a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.167
alpha amino acid metabolic process GO:1901605 71 0.129
cellular amino acid metabolic process GO:0006520 107 0.126
carboxylic acid metabolic process GO:0019752 289 0.122
organic acid metabolic process GO:0006082 292 0.102
cellular response to endogenous stimulus GO:0071495 377 0.096
intracellular signal transduction GO:0035556 314 0.094
response to hypoxia GO:0001666 231 0.093
alpha amino acid biosynthetic process GO:1901607 23 0.086
hepaticobiliary system development GO:0061008 90 0.084
monocarboxylic acid metabolic process GO:0032787 152 0.078
programmed cell death GO:0012501 392 0.076
cellular amino acid biosynthetic process GO:0008652 32 0.072
single organism biosynthetic process GO:0044711 342 0.072
organic acid biosynthetic process GO:0016053 83 0.071
response to oxidative stress GO:0006979 186 0.070
tissue development GO:0009888 252 0.067
single organism reproductive process GO:0044702 297 0.065
amide biosynthetic process GO:0043604 10 0.064
small molecule biosynthetic process GO:0044283 124 0.064
cellular response to stress GO:0033554 269 0.063
regulation of cellular component organization GO:0051128 368 0.062
anion transport GO:0006820 178 0.061
cellular response to nitrogen compound GO:1901699 210 0.059
response to peptide hormone GO:0043434 278 0.058
organic anion transport GO:0015711 132 0.057
apoptotic process GO:0006915 381 0.057
response to oxygen levels GO:0070482 265 0.057
regulation of apoptotic process GO:0042981 335 0.056
liver development GO:0001889 90 0.056
cellular response to external stimulus GO:0071496 118 0.055
reproductive process GO:0022414 372 0.054
response to toxic substance GO:0009636 133 0.053
rna metabolic process GO:0016070 406 0.053
anatomical structure morphogenesis GO:0009653 298 0.052
regulation of protein metabolic process GO:0051246 289 0.048
negative regulation of cell death GO:0060548 229 0.046
cellular response to hormone stimulus GO:0032870 247 0.046
cellular catabolic process GO:0044248 295 0.045
aging GO:0007568 241 0.044
response to nutrient levels GO:0031667 370 0.044
amine metabolic process GO:0009308 38 0.044
head development GO:0060322 247 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
chemical homeostasis GO:0048878 292 0.042
central nervous system development GO:0007417 311 0.041
gland development GO:0048732 155 0.040
rna biosynthetic process GO:0032774 380 0.040
response to metal ion GO:0010038 253 0.040
response to carbohydrate GO:0009743 183 0.040
carboxylic acid biosynthetic process GO:0046394 83 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.040
negative regulation of apoptotic process GO:0043066 181 0.039
reproduction GO:0000003 245 0.038
cellular lipid metabolic process GO:0044255 208 0.038
response to decreased oxygen levels GO:0036293 237 0.038
response to inorganic substance GO:0010035 377 0.037
response to extracellular stimulus GO:0009991 380 0.037
circulatory system development GO:0072359 134 0.036
lipid metabolic process GO:0006629 283 0.036
epithelium development GO:0060429 96 0.036
cellular amine metabolic process GO:0044106 38 0.035
response to peptide GO:1901652 292 0.035
cellular amide metabolic process GO:0043603 44 0.035
positive regulation of rna biosynthetic process GO:1902680 197 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
negative regulation of metabolic process GO:0009892 331 0.034
neuron differentiation GO:0030182 368 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
multicellular organism reproduction GO:0032504 233 0.034
protein complex subunit organization GO:0071822 302 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
reproductive structure development GO:0048608 128 0.033
cellular ketone metabolic process GO:0042180 51 0.033
protein complex biogenesis GO:0070271 263 0.033
branched chain amino acid transport GO:0015803 2 0.032
vesicle mediated transport GO:0016192 181 0.032
response to starvation GO:0042594 59 0.032
brain development GO:0007420 247 0.032
response to external biotic stimulus GO:0043207 221 0.032
regulation of molecular function GO:0065009 398 0.032
lipid biosynthetic process GO:0008610 128 0.032
homeostatic process GO:0042592 331 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
regulation of cell differentiation GO:0045595 320 0.031
response to monosaccharide GO:0034284 159 0.031
regulation of cell cycle GO:0051726 73 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
response to nutrient GO:0007584 248 0.030
regulation of catalytic activity GO:0050790 304 0.030
protein localization GO:0008104 191 0.030
positive regulation of gene expression GO:0010628 244 0.029
response to other organism GO:0051707 220 0.028
endocytosis GO:0006897 84 0.028
multi organism reproductive process GO:0044703 262 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
cellular component biogenesis GO:0044085 368 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
protein complex assembly GO:0006461 263 0.028
regulation of hydrolase activity GO:0051336 143 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
response to acid chemical GO:0001101 222 0.028
gonad development GO:0008406 104 0.027
response to amino acid GO:0043200 75 0.027
response to insulin GO:0032868 133 0.027
response to hexose GO:0009746 144 0.027
cellular component assembly GO:0022607 360 0.027
regulation of transcription dna templated GO:0006355 374 0.027
organonitrogen compound biosynthetic process GO:1901566 167 0.027
cellular homeostasis GO:0019725 252 0.027
regulation of rna metabolic process GO:0051252 391 0.026
transmembrane transport GO:0055085 412 0.026
neuron development GO:0048666 286 0.026
circulatory system process GO:0003013 183 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
negative regulation of gene expression GO:0010629 199 0.026
reproductive system development GO:0061458 128 0.026
cellular component movement GO:0006928 248 0.026
regulation of programmed cell death GO:0043067 341 0.026
purine containing compound metabolic process GO:0072521 253 0.026
developmental process involved in reproduction GO:0003006 159 0.025
response to glucose GO:0009749 136 0.025
aspartate family amino acid biosynthetic process GO:0009067 4 0.025
catabolic process GO:0009056 351 0.024
single organism intracellular transport GO:1902582 166 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
nitrogen compound transport GO:0071705 229 0.024
cell cycle GO:0007049 101 0.024
epithelial cell differentiation GO:0030855 71 0.023
organelle organization GO:0006996 266 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
cardiovascular system development GO:0072358 134 0.023
nucleic acid templated transcription GO:0097659 379 0.023
sexual reproduction GO:0019953 148 0.023
neurological system process GO:0050877 219 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of cell proliferation GO:0042127 359 0.022
kidney development GO:0001822 67 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
tube development GO:0035295 89 0.022
single organism catabolic process GO:0044712 283 0.022
sex differentiation GO:0007548 113 0.022
renal system development GO:0072001 67 0.021
positive regulation of molecular function GO:0044093 230 0.021
defense response GO:0006952 194 0.021
carboxylic acid transport GO:0046942 115 0.021
protein phosphorylation GO:0006468 345 0.021
response to estrogen GO:0043627 232 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of ion transport GO:0043269 245 0.021
secretion by cell GO:0032940 248 0.021
regulation of secretion by cell GO:1903530 208 0.021
growth GO:0040007 165 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
negative regulation of developmental process GO:0051093 125 0.020
cation transport GO:0006812 382 0.020
cellular chemical homeostasis GO:0055082 247 0.020
regulation of cellular localization GO:0060341 263 0.020
development of primary sexual characteristics GO:0045137 107 0.020
neuron projection development GO:0031175 273 0.020
secretion GO:0046903 307 0.019
regulation of neuron differentiation GO:0045664 208 0.019
response to mechanical stimulus GO:0009612 134 0.019
cell projection organization GO:0030030 302 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
transcription dna templated GO:0006351 377 0.019
regulation of catabolic process GO:0009894 113 0.019
response to reactive oxygen species GO:0000302 120 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
gamete generation GO:0007276 124 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
nucleotide metabolic process GO:0009117 279 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
response to hydrogen peroxide GO:0042542 89 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
tetrapyrrole metabolic process GO:0033013 11 0.018
gastrulation GO:0007369 2 0.018
intracellular transport GO:0046907 185 0.018
ion homeostasis GO:0050801 212 0.018
macromolecular complex assembly GO:0065003 273 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
response to estradiol GO:0032355 164 0.018
fatty acid metabolic process GO:0006631 99 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
hormone metabolic process GO:0042445 69 0.018
response to biotic stimulus GO:0009607 226 0.018
macromolecule localization GO:0033036 252 0.017
response to radiation GO:0009314 137 0.017
positive regulation of developmental process GO:0051094 283 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
amino acid transport GO:0006865 70 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
protein oligomerization GO:0051259 191 0.017
oxidation reduction process GO:0055114 304 0.017
spermatogenesis GO:0007283 99 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
negative regulation of signaling GO:0023057 157 0.017
organic acid transport GO:0015849 116 0.016
regulation of cell development GO:0060284 263 0.016
urogenital system development GO:0001655 78 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
immune system process GO:0002376 204 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.016
response to light stimulus GO:0009416 52 0.016
response to lipopolysaccharide GO:0032496 191 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
negative regulation of transport GO:0051051 136 0.016
cellular response to peptide GO:1901653 133 0.015
response to alkaloid GO:0043279 132 0.015
response to ethanol GO:0045471 162 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
negative regulation of molecular function GO:0044092 133 0.015
aspartate family amino acid metabolic process GO:0009066 10 0.015
regulation of response to stress GO:0080134 126 0.015
rhythmic process GO:0048511 156 0.015
regulation of signal transduction GO:0009966 318 0.015
neuron death GO:0070997 127 0.015
exocytosis GO:0006887 60 0.015
cellular response to lipid GO:0071396 201 0.015
establishment of tissue polarity GO:0007164 2 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
cell type specific apoptotic process GO:0097285 134 0.015
male gamete generation GO:0048232 99 0.015
divalent inorganic cation transport GO:0072511 134 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of neuron death GO:1901214 115 0.014
establishment of protein localization GO:0045184 141 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
ion transmembrane transport GO:0034220 365 0.014
cellular response to lipopolysaccharide GO:0071222 55 0.014
metal ion transport GO:0030001 289 0.014
response to camp GO:0051591 91 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to bacterium GO:0009617 200 0.014
response to glucocorticoid GO:0051384 223 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
cellular response to reactive oxygen species GO:0034614 55 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
blood vessel development GO:0001568 69 0.014
vitamin transport GO:0051180 14 0.014
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.013
b cell differentiation GO:0030183 2 0.013
divalent metal ion transport GO:0070838 132 0.013
cellular response to nutrient levels GO:0031669 60 0.013
proteolysis GO:0006508 175 0.013
regulation of immunoglobulin production GO:0002637 4 0.013
multi multicellular organism process GO:0044706 138 0.013
cellular response to starvation GO:0009267 27 0.013
membrane organization GO:0061024 94 0.013
organ morphogenesis GO:0009887 75 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of immune system process GO:0002684 90 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of system process GO:0044057 208 0.013
regulation of neuron projection development GO:0010975 161 0.013
multicellular organism growth GO:0035264 1 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
positive regulation of transport GO:0051050 245 0.013
blood circulation GO:0008015 183 0.013
cation homeostasis GO:0055080 195 0.013
regulation of cell projection organization GO:0031344 175 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
heterocycle catabolic process GO:0046700 167 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
cell growth GO:0016049 104 0.012
negative regulation of cell communication GO:0010648 158 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of immune system process GO:0002682 123 0.012
regulation of membrane potential GO:0042391 110 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
dendrite development GO:0016358 72 0.012
maintenance of location GO:0051235 17 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular ion homeostasis GO:0006873 184 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
regulation of blood pressure GO:0008217 83 0.012
single organism membrane organization GO:0044802 74 0.011
localization of cell GO:0051674 202 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
ras protein signal transduction GO:0007265 29 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
lipid storage GO:0019915 1 0.011
calcium ion transport GO:0006816 131 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
organic hydroxy compound transport GO:0015850 77 0.011
cellular response to oxidative stress GO:0034599 76 0.011
retinal metabolic process GO:0042574 3 0.011
neural crest cell development GO:0014032 2 0.011
regulation of immunoglobulin secretion GO:0051023 1 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cellular response to topologically incorrect protein GO:0035967 3 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cellular modified amino acid biosynthetic process GO:0042398 18 0.011
response to temperature stimulus GO:0009266 94 0.011
single organism organelle organization GO:1902589 180 0.011
positive regulation of signaling GO:0023056 270 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
regulation of metal ion transport GO:0010959 118 0.011
positive regulation of nervous system development GO:0051962 178 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
cell activation GO:0001775 97 0.011
regulation of body fluid levels GO:0050878 90 0.011
glycerolipid metabolic process GO:0046486 67 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
morphogenesis of a polarized epithelium GO:0001738 1 0.010
response to growth factor GO:0070848 189 0.010
regulation of protein localization GO:0032880 81 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
eye morphogenesis GO:0048592 4 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
positive regulation of immunoglobulin production GO:0002639 4 0.010
response to gonadotropin GO:0034698 34 0.010
lipid modification GO:0030258 52 0.010
vasculature development GO:0001944 70 0.010
carbohydrate homeostasis GO:0033500 75 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
lipid localization GO:0010876 62 0.010
cellular protein localization GO:0034613 122 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
regulation of growth GO:0040008 105 0.010

Slc3a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.064
neuromuscular disease DOID:440 0 0.022
charcot marie tooth disease type 2 DOID:0050539 0 0.022
charcot marie tooth disease DOID:10595 0 0.022
neuropathy DOID:870 0 0.022
central nervous system disease DOID:331 0 0.019
disease of metabolism DOID:0014667 0 0.014
amino acid metabolic disorder DOID:9252 0 0.014
inherited metabolic disorder DOID:655 0 0.014