Rattus norvegicus

0 known processes

Tmc2

transmembrane channel-like 2

Tmc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.055
reproductive process GO:0022414 372 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
organic acid metabolic process GO:0006082 292 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
single organism biosynthetic process GO:0044711 342 0.038
nucleic acid templated transcription GO:0097659 379 0.035
rna biosynthetic process GO:0032774 380 0.035
cellular amino acid metabolic process GO:0006520 107 0.034
protein phosphorylation GO:0006468 345 0.034
rna metabolic process GO:0016070 406 0.033
regulation of rna metabolic process GO:0051252 391 0.033
cellular ketone metabolic process GO:0042180 51 0.033
amine metabolic process GO:0009308 38 0.032
cellular amine metabolic process GO:0044106 38 0.031
regulation of molecular function GO:0065009 398 0.031
cellular component assembly GO:0022607 360 0.031
tissue development GO:0009888 252 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of transcription dna templated GO:0006355 374 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
programmed cell death GO:0012501 392 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
response to extracellular stimulus GO:0009991 380 0.030
cation transport GO:0006812 382 0.030
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.029
cellular component biogenesis GO:0044085 368 0.029
regulation of cell proliferation GO:0042127 359 0.029
lipid metabolic process GO:0006629 283 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
locomotion GO:0040011 237 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
transcription dna templated GO:0006351 377 0.028
neuron differentiation GO:0030182 368 0.028
regulation of cell differentiation GO:0045595 320 0.028
homeostatic process GO:0042592 331 0.028
cell cell signaling GO:0007267 335 0.028
multicellular organism reproduction GO:0032504 233 0.028
regulation of programmed cell death GO:0043067 341 0.028
single organism reproductive process GO:0044702 297 0.028
chemical homeostasis GO:0048878 292 0.027
intracellular signal transduction GO:0035556 314 0.027
secretion GO:0046903 307 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
positive regulation of gene expression GO:0010628 244 0.027
response to peptide GO:1901652 292 0.026
response to inorganic substance GO:0010035 377 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
cellular homeostasis GO:0019725 252 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
response to peptide hormone GO:0043434 278 0.026
negative regulation of metabolic process GO:0009892 331 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
protein complex assembly GO:0006461 263 0.025
organophosphate metabolic process GO:0019637 370 0.025
response to nutrient levels GO:0031667 370 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
regulation of protein metabolic process GO:0051246 289 0.025
secretion by cell GO:0032940 248 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
neuron development GO:0048666 286 0.025
regulation of catalytic activity GO:0050790 304 0.025
response to oxygen levels GO:0070482 265 0.024
regulation of cellular component organization GO:0051128 368 0.024
reproduction GO:0000003 245 0.024
regulation of secretion GO:0051046 224 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
neurological system process GO:0050877 219 0.024
Mouse
regulation of cellular localization GO:0060341 263 0.024
apoptotic process GO:0006915 381 0.024
central nervous system development GO:0007417 311 0.024
response to metal ion GO:0010038 253 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
metal ion transport GO:0030001 289 0.023
Mouse
multi organism reproductive process GO:0044703 262 0.023
catabolic process GO:0009056 351 0.023
regulation of apoptotic process GO:0042981 335 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of system process GO:0044057 208 0.023
brain development GO:0007420 247 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
response to wounding GO:0009611 254 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.022
cellular chemical homeostasis GO:0055082 247 0.022
ion homeostasis GO:0050801 212 0.022
head development GO:0060322 247 0.022
cell projection organization GO:0030030 302 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
nucleotide metabolic process GO:0009117 279 0.022
positive regulation of molecular function GO:0044093 230 0.021
cellular component movement GO:0006928 248 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
response to acid chemical GO:0001101 222 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of phosphorylation GO:0042325 248 0.021
neuron projection development GO:0031175 273 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
single organism catabolic process GO:0044712 283 0.021
positive regulation of transport GO:0051050 245 0.021
anion transport GO:0006820 178 0.021
positive regulation of signaling GO:0023056 270 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
circulatory system process GO:0003013 183 0.020
positive regulation of cell communication GO:0010647 271 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
ion transmembrane transport GO:0034220 365 0.020
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
positive regulation of developmental process GO:0051094 283 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
regulation of hormone levels GO:0010817 187 0.020
response to hypoxia GO:0001666 231 0.020
macromolecular complex assembly GO:0065003 273 0.020
blood circulation GO:0008015 183 0.020
regulation of secretion by cell GO:1903530 208 0.020
cellular catabolic process GO:0044248 295 0.020
localization of cell GO:0051674 202 0.020
purine containing compound metabolic process GO:0072521 253 0.020
transmembrane transport GO:0055085 412 0.020
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
cellular lipid metabolic process GO:0044255 208 0.019
heart morphogenesis GO:0003007 3 0.019
protein complex biogenesis GO:0070271 263 0.019
response to decreased oxygen levels GO:0036293 237 0.019
nitrogen compound transport GO:0071705 229 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cellular response to stress GO:0033554 269 0.019
signal release GO:0023061 145 0.019
negative regulation of cell death GO:0060548 229 0.018
aging GO:0007568 241 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of cell development GO:0060284 263 0.018
cation homeostasis GO:0055080 195 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
regulation of signal transduction GO:0009966 318 0.018
oxidation reduction process GO:0055114 304 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
protein complex subunit organization GO:0071822 302 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
response to mechanical stimulus GO:0009612 134 0.018
Mouse
organic substance catabolic process GO:1901575 316 0.018
regulation of protein modification process GO:0031399 194 0.018
cellular ion homeostasis GO:0006873 184 0.018
sexual reproduction GO:0019953 148 0.017
positive regulation of cell death GO:0010942 184 0.017
gland development GO:0048732 155 0.017
cardiovascular system development GO:0072358 134 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
response to corticosteroid GO:0031960 235 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cellular cation homeostasis GO:0030003 180 0.017
synaptic transmission GO:0007268 235 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
macromolecule localization GO:0033036 252 0.017
organelle organization GO:0006996 266 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
cell motility GO:0048870 202 0.017
epithelium development GO:0060429 96 0.017
response to estrogen GO:0043627 232 0.017
developmental process involved in reproduction GO:0003006 159 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of hormone secretion GO:0046883 106 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
response to glucocorticoid GO:0051384 223 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
negative regulation of gene expression GO:0010629 199 0.016
negative regulation of molecular function GO:0044092 133 0.016
circulatory system development GO:0072359 134 0.016
intracellular transport GO:0046907 185 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of nervous system development GO:0051960 264 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
defense response GO:0006952 194 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
anterior posterior pattern specification GO:0009952 1 0.016
response to oxidative stress GO:0006979 186 0.016
behavior GO:0007610 205 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
Mouse
cell migration GO:0016477 197 0.016
growth GO:0040007 165 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
response to ketone GO:1901654 182 0.015
positive regulation of secretion GO:0051047 140 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
reproductive structure development GO:0048608 128 0.015
response to nutrient GO:0007584 248 0.015
axis specification GO:0009798 4 0.015
limb morphogenesis GO:0035108 4 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
response to carbohydrate GO:0009743 183 0.015
response to ethanol GO:0045471 162 0.015
proteolysis GO:0006508 175 0.015
metal ion homeostasis GO:0055065 186 0.015
small molecule biosynthetic process GO:0044283 124 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
carboxylic acid transport GO:0046942 115 0.015
positive regulation of protein modification process GO:0031401 142 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
lipid biosynthetic process GO:0008610 128 0.014
ras protein signal transduction GO:0007265 29 0.014
response to monosaccharide GO:0034284 159 0.014
reproductive system development GO:0061458 128 0.014
response to growth factor GO:0070848 189 0.014
protein oligomerization GO:0051259 191 0.014
regulation of membrane potential GO:0042391 110 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
regulation of ion transport GO:0043269 245 0.014
Mouse
organophosphate biosynthetic process GO:0090407 143 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
hormone transport GO:0009914 121 0.014
cellular response to lipid GO:0071396 201 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
cation transmembrane transport GO:0098655 263 0.014
Mouse
establishment of tissue polarity GO:0007164 2 0.014
wound healing GO:0042060 122 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of cell projection organization GO:0031344 175 0.014
cell adhesion GO:0007155 110 0.014
inflammatory response GO:0006954 150 0.014
organic acid transport GO:0015849 116 0.014
response to hexose GO:0009746 144 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
response to glucose GO:0009749 136 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
gonad development GO:0008406 104 0.014
regulation of neuron projection development GO:0010975 161 0.014
hormone secretion GO:0046879 115 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of blood circulation GO:1903522 110 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
rhythmic process GO:0048511 156 0.013
multi multicellular organism process GO:0044706 138 0.013
nucleoside metabolic process GO:0009116 179 0.013
divalent inorganic cation transport GO:0072511 134 0.013
Mouse
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
organic anion transport GO:0015711 132 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of signal transduction GO:0009967 175 0.013
carbohydrate metabolic process GO:0005975 130 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
embryonic appendage morphogenesis GO:0035113 4 0.013
gamete generation GO:0007276 124 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of hydrolase activity GO:0051336 143 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
gastrulation GO:0007369 2 0.013
response to lipopolysaccharide GO:0032496 191 0.013
chromosome segregation GO:0007059 2 0.013
appendage morphogenesis GO:0035107 4 0.013
negative regulation of cell communication GO:0010648 158 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cellular response to peptide GO:1901653 133 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to external biotic stimulus GO:0043207 221 0.013
immune system process GO:0002376 204 0.013
regeneration GO:0031099 163 0.013
response to bacterium GO:0009617 200 0.013
development of primary sexual characteristics GO:0045137 107 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of synaptic transmission GO:0050804 141 0.013
eye morphogenesis GO:0048592 4 0.013
cell type specific apoptotic process GO:0097285 134 0.012
response to purine containing compound GO:0014074 126 0.012
calcium ion transport GO:0006816 131 0.012
Mouse
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to other organism GO:0051707 220 0.012
regulation of homeostatic process GO:0032844 101 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
response to reactive oxygen species GO:0000302 120 0.012
heterocycle catabolic process GO:0046700 167 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of kinase activity GO:0043549 117 0.012
divalent metal ion transport GO:0070838 132 0.012
Mouse
regulation of locomotion GO:0040012 148 0.012
protein localization GO:0008104 191 0.012
cell part morphogenesis GO:0032990 123 0.012
cellular component morphogenesis GO:0032989 155 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
axon development GO:0061564 96 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
response to estradiol GO:0032355 164 0.012
muscle system process GO:0003012 115 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
biological adhesion GO:0022610 110 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of metal ion transport GO:0010959 118 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to biotic stimulus GO:0009607 226 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
aromatic compound catabolic process GO:0019439 168 0.011
tube development GO:0035295 89 0.011
sensory perception GO:0007600 101 0.011
Mouse
cellular response to external stimulus GO:0071496 118 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
sex differentiation GO:0007548 113 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
vascular process in circulatory system GO:0003018 96 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of innate immune response GO:0045824 4 0.011
spermatogenesis GO:0007283 99 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
response to radiation GO:0009314 137 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of transferase activity GO:0051338 123 0.011
cellular macromolecule localization GO:0070727 122 0.011
muscle structure development GO:0061061 87 0.011
regulation of immune system process GO:0002682 123 0.011
response to alkaloid GO:0043279 132 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
negative regulation of developmental process GO:0051093 125 0.011
response to insulin GO:0032868 133 0.011
female pregnancy GO:0007565 122 0.011
amide transport GO:0042886 105 0.011
regulation of response to stress GO:0080134 126 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
lipid storage GO:0019915 1 0.011
embryonic pattern specification GO:0009880 1 0.011
muscle cell proliferation GO:0033002 84 0.011
positive regulation of cell development GO:0010720 176 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
mapk cascade GO:0000165 140 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
male gamete generation GO:0048232 99 0.011
response to toxic substance GO:0009636 133 0.011
negative regulation of secretion GO:0051048 82 0.011
peptidyl amino acid modification GO:0018193 126 0.011
organophosphate catabolic process GO:0046434 148 0.011
cell morphogenesis GO:0000902 142 0.011
nucleotide catabolic process GO:0009166 139 0.011
positive regulation of immune system process GO:0002684 90 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
meiotic cell cycle process GO:1903046 3 0.011
transmission of nerve impulse GO:0019226 42 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
vesicle mediated transport GO:0016192 181 0.011
reactive oxygen species metabolic process GO:0072593 37 0.010
sequestering of calcium ion GO:0051208 8 0.010
heart development GO:0007507 72 0.010
regulation of peptide transport GO:0090087 87 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
cardiac chamber development GO:0003205 1 0.010
establishment of planar polarity GO:0001736 1 0.010
leukocyte cell cell adhesion GO:0007159 4 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
fatty acid metabolic process GO:0006631 99 0.010
regulation of peptide secretion GO:0002791 82 0.010
embryonic skeletal system development GO:0048706 3 0.010
spindle organization GO:0007051 2 0.010
action potential GO:0001508 54 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
single organism organelle organization GO:1902589 180 0.010
regulation of blood vessel size GO:0050880 89 0.010
sensory perception of pain GO:0019233 73 0.010
chemosensory behavior GO:0007635 2 0.010
single organism behavior GO:0044708 130 0.010
cofactor metabolic process GO:0051186 95 0.010
peptide transport GO:0015833 97 0.010
response to cytokine GO:0034097 215 0.010
epithelial cell differentiation GO:0030855 71 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
response to vitamin GO:0033273 131 0.010
regulation of protein kinase activity GO:0045859 105 0.010
salivary gland development GO:0007431 3 0.010

Tmc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
sensory system disease DOID:0050155 0 0.015
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.014
eye and adnexa disease DOID:1492 0 0.012
central nervous system disease DOID:331 0 0.011
eye disease DOID:5614 0 0.011
inherited metabolic disorder DOID:655 0 0.010