Rattus norvegicus

0 known processes

Pbx1

pre-B-cell leukemia homeobox 1

Pbx1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.110
Human
transcription dna templated GO:0006351 377 0.096
Human
regulation of rna metabolic process GO:0051252 391 0.084
Human
rna metabolic process GO:0016070 406 0.076
Human
regulation of rna biosynthetic process GO:2001141 381 0.072
Human
nucleic acid templated transcription GO:0097659 379 0.070
Human
regulation of transcription dna templated GO:0006355 374 0.069
Human
regulation of multicellular organismal development GO:2000026 376 0.068
regulation of nucleic acid templated transcription GO:1903506 380 0.066
Human
regulation of molecular function GO:0065009 398 0.059
Human
tissue development GO:0009888 252 0.059
regulation of cellular component organization GO:0051128 368 0.058
regulation of cell proliferation GO:0042127 359 0.058
negative regulation of metabolic process GO:0009892 331 0.055
negative regulation of cellular metabolic process GO:0031324 281 0.054
programmed cell death GO:0012501 392 0.053
regulation of apoptotic process GO:0042981 335 0.051
apoptotic process GO:0006915 381 0.047
regulation of signal transduction GO:0009966 318 0.047
reproductive process GO:0022414 372 0.047
cellular component assembly GO:0022607 360 0.047
positive regulation of biosynthetic process GO:0009891 319 0.046
transcription from rna polymerase ii promoter GO:0006366 252 0.045
regulation of cell differentiation GO:0045595 320 0.044
regulation of programmed cell death GO:0043067 341 0.044
intracellular signal transduction GO:0035556 314 0.043
cellular component biogenesis GO:0044085 368 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
anatomical structure morphogenesis GO:0009653 298 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
neuron differentiation GO:0030182 368 0.041
cellular response to endogenous stimulus GO:0071495 377 0.038
single organism reproductive process GO:0044702 297 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
negative regulation of gene expression GO:0010629 199 0.035
multicellular organism reproduction GO:0032504 233 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
regulation of cell development GO:0060284 263 0.035
response to extracellular stimulus GO:0009991 380 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.034
positive regulation of developmental process GO:0051094 283 0.034
regulation of protein metabolic process GO:0051246 289 0.033
organic acid metabolic process GO:0006082 292 0.033
protein phosphorylation GO:0006468 345 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
central nervous system development GO:0007417 311 0.032
brain development GO:0007420 247 0.032
amine metabolic process GO:0009308 38 0.032
multi organism reproductive process GO:0044703 262 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.031
positive regulation of gene expression GO:0010628 244 0.031
macromolecular complex assembly GO:0065003 273 0.031
neuron projection development GO:0031175 273 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
positive regulation of cell death GO:0010942 184 0.031
regulation of catalytic activity GO:0050790 304 0.031
negative regulation of nucleic acid templated transcription GO:1903507 117 0.031
head development GO:0060322 247 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
sexual reproduction GO:0019953 148 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
protein complex assembly GO:0006461 263 0.029
positive regulation of cell differentiation GO:0045597 217 0.028
neuron development GO:0048666 286 0.028
cellular amine metabolic process GO:0044106 38 0.028
positive regulation of cell communication GO:0010647 271 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
cell projection organization GO:0030030 302 0.028
response to nutrient GO:0007584 248 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.027
organelle organization GO:0006996 266 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
regulation of neurogenesis GO:0050767 247 0.027
cell cell signaling GO:0007267 335 0.027
cellular homeostasis GO:0019725 252 0.027
cellular chemical homeostasis GO:0055082 247 0.027
protein complex biogenesis GO:0070271 263 0.027
response to nutrient levels GO:0031667 370 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
oxoacid metabolic process GO:0043436 290 0.026
cellular component movement GO:0006928 248 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
cellular ketone metabolic process GO:0042180 51 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
single organism biosynthetic process GO:0044711 342 0.025
cellular calcium ion homeostasis GO:0006874 160 0.025
regulation of nervous system development GO:0051960 264 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
positive regulation of cell development GO:0010720 176 0.024
response to growth factor GO:0070848 189 0.024
regulation of phosphorylation GO:0042325 248 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
positive regulation of nervous system development GO:0051962 178 0.023
eye morphogenesis GO:0048592 4 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
metal ion homeostasis GO:0055065 186 0.023
cell motility GO:0048870 202 0.023
cellular metal ion homeostasis GO:0006875 172 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
response to inorganic substance GO:0010035 377 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
cation homeostasis GO:0055080 195 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
catabolic process GO:0009056 351 0.023
positive regulation of transport GO:0051050 245 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
lipid metabolic process GO:0006629 283 0.022
positive regulation of molecular function GO:0044093 230 0.022
response to peptide hormone GO:0043434 278 0.022
aging GO:0007568 241 0.022
cardiovascular system development GO:0072358 134 0.022
response to oxygen levels GO:0070482 265 0.022
heart morphogenesis GO:0003007 3 0.021
negative regulation of cell death GO:0060548 229 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
response to decreased oxygen levels GO:0036293 237 0.021
single organism organelle organization GO:1902589 180 0.021
circulatory system development GO:0072359 134 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of neuron differentiation GO:0045664 208 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
positive regulation of cellular component organization GO:0051130 200 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
response to peptide GO:1901652 292 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
cell migration GO:0016477 197 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
gamete generation GO:0007276 124 0.020
response to wounding GO:0009611 254 0.020
reproduction GO:0000003 245 0.020
cell morphogenesis GO:0000902 142 0.020
cation transport GO:0006812 382 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
response to estrogen GO:0043627 232 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
cellular catabolic process GO:0044248 295 0.020
response to metal ion GO:0010038 253 0.020
regulation of cellular localization GO:0060341 263 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
negative regulation of cell communication GO:0010648 158 0.019
regulation of cell projection organization GO:0031344 175 0.019
cellular response to stress GO:0033554 269 0.019
cell cycle GO:0007049 101 0.019
cellular response to lipid GO:0071396 201 0.018
chemical homeostasis GO:0048878 292 0.018
developmental process involved in reproduction GO:0003006 159 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
locomotion GO:0040011 237 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of secretion GO:0051047 140 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
rhythmic process GO:0048511 156 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
sensory organ development GO:0007423 74 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
calcium ion homeostasis GO:0055074 162 0.017
ion transmembrane transport GO:0034220 365 0.017
ion homeostasis GO:0050801 212 0.017
anterior posterior pattern specification GO:0009952 1 0.017
homeostatic process GO:0042592 331 0.017
cellular ion homeostasis GO:0006873 184 0.017
negative regulation of developmental process GO:0051093 125 0.017
protein oligomerization GO:0051259 191 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
response to hypoxia GO:0001666 231 0.017
multi multicellular organism process GO:0044706 138 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
renal system development GO:0072001 67 0.017
response to acid chemical GO:0001101 222 0.016
cell type specific apoptotic process GO:0097285 134 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
kidney development GO:0001822 67 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of membrane potential GO:0042391 110 0.016
gland development GO:0048732 155 0.016
regeneration GO:0031099 163 0.016
negative regulation of signaling GO:0023057 157 0.016
protein complex subunit organization GO:0071822 302 0.016
positive regulation of protein modification process GO:0031401 142 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
axis specification GO:0009798 4 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
negative regulation of molecular function GO:0044092 133 0.016
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
metal ion transport GO:0030001 289 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
embryonic pattern specification GO:0009880 1 0.015
regulation of system process GO:0044057 208 0.015
cellular cation homeostasis GO:0030003 180 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
response to corticosteroid GO:0031960 235 0.015
gastrulation GO:0007369 2 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
proteolysis GO:0006508 175 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to bacterium GO:0009617 200 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
cellular response to peptide GO:1901653 133 0.015
biological adhesion GO:0022610 110 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
negative regulation of protein metabolic process GO:0051248 114 0.014
muscle structure development GO:0061061 87 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
organ morphogenesis GO:0009887 75 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
secretion GO:0046903 307 0.014
vasculature development GO:0001944 70 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
ras protein signal transduction GO:0007265 29 0.014
urogenital system development GO:0001655 78 0.014
positive regulation of catalytic activity GO:0043085 184 0.013
response to ethanol GO:0045471 162 0.013
single organism catabolic process GO:0044712 283 0.013
neurological system process GO:0050877 219 0.013
muscle system process GO:0003012 115 0.013
response to estradiol GO:0032355 164 0.013
response to cytokine GO:0034097 215 0.013
chromosome segregation GO:0007059 2 0.013
cell cycle process GO:0022402 57 0.013
response to toxic substance GO:0009636 133 0.013
organ regeneration GO:0031100 101 0.013
single organism cellular localization GO:1902580 102 0.013
peptidyl amino acid modification GO:0018193 126 0.013
macromolecule localization GO:0033036 252 0.013
spermatogenesis GO:0007283 99 0.013
vesicle mediated transport GO:0016192 181 0.013
epithelium development GO:0060429 96 0.013
wound healing GO:0042060 122 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
response to monosaccharide GO:0034284 159 0.013
response to biotic stimulus GO:0009607 226 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
protein localization GO:0008104 191 0.013
regulation of secretion GO:0051046 224 0.013
regulation of kinase activity GO:0043549 117 0.013
response to ketone GO:1901654 182 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of fat cell differentiation GO:0045598 3 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of secretion by cell GO:1903530 208 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
response to hexose GO:0009746 144 0.012
male gamete generation GO:0048232 99 0.012
organic substance catabolic process GO:1901575 316 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
localization of cell GO:0051674 202 0.012
positive regulation of cell migration GO:0030335 96 0.012
camera type eye morphogenesis GO:0048593 2 0.012
multicellular organism growth GO:0035264 1 0.012
response to oxidative stress GO:0006979 186 0.012
blood circulation GO:0008015 183 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
cell adhesion GO:0007155 110 0.012
blood vessel development GO:0001568 69 0.012
organophosphate metabolic process GO:0019637 370 0.012
response to mechanical stimulus GO:0009612 134 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
intracellular transport GO:0046907 185 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
carbohydrate metabolic process GO:0005975 130 0.012
response to glucocorticoid GO:0051384 223 0.012
nucleotide metabolic process GO:0009117 279 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
cellular component morphogenesis GO:0032989 155 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
response to glucose GO:0009749 136 0.012
regulation of ion transport GO:0043269 245 0.012
response to carbohydrate GO:0009743 183 0.012
reproductive structure development GO:0048608 128 0.012
camera type eye development GO:0043010 48 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
female pregnancy GO:0007565 122 0.011
cellular protein localization GO:0034613 122 0.011
transmembrane transport GO:0055085 412 0.011
regulation of transferase activity GO:0051338 123 0.011
ossification GO:0001503 70 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
forebrain development GO:0030900 98 0.011
mapk cascade GO:0000165 140 0.011
cell projection morphogenesis GO:0048858 123 0.011
response to radiation GO:0009314 137 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
neuron apoptotic process GO:0051402 88 0.011
cytoplasmic transport GO:0016482 115 0.011
immune system process GO:0002376 204 0.011
tube development GO:0035295 89 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of signal transduction GO:0009967 175 0.011
developmental growth GO:0048589 100 0.011
neuron death GO:0070997 127 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cell growth GO:0016049 104 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of signal transduction GO:0009968 83 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
muscle cell proliferation GO:0033002 84 0.011
response to other organism GO:0051707 220 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
regulation of growth GO:0040008 105 0.011
response to temperature stimulus GO:0009266 94 0.011
adult locomotory behavior GO:0008344 4 0.011
epithelial cell differentiation GO:0030855 71 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
striated muscle tissue development GO:0014706 58 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
growth GO:0040007 165 0.010
response to alkaloid GO:0043279 132 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
defense response GO:0006952 194 0.010
regulation of ossification GO:0030278 32 0.010
embryonic appendage morphogenesis GO:0035113 4 0.010
response to lipopolysaccharide GO:0032496 191 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
regulation of neuron death GO:1901214 115 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
neuron projection morphogenesis GO:0048812 122 0.010

Pbx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.012
musculoskeletal system disease DOID:17 0 0.011
inherited metabolic disorder DOID:655 0 0.011