Rattus norvegicus

27 known processes

Pdlim7

PDZ and LIM domain 7

(Aliases: Enigma)

Pdlim7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
regulation of transcription dna templated GO:0006355 374 0.053
cellular response to oxygen containing compound GO:1901701 386 0.053
regulation of rna metabolic process GO:0051252 391 0.050
regulation of multicellular organismal development GO:2000026 376 0.049
Rat
tissue development GO:0009888 252 0.048
transcription dna templated GO:0006351 377 0.048
nucleic acid templated transcription GO:0097659 379 0.047
rna biosynthetic process GO:0032774 380 0.047
cellular response to endogenous stimulus GO:0071495 377 0.040
positive regulation of gene expression GO:0010628 244 0.039
organonitrogen compound biosynthetic process GO:1901566 167 0.039
response to extracellular stimulus GO:0009991 380 0.038
rna metabolic process GO:0016070 406 0.038
regulation of cell differentiation GO:0045595 320 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
response to nutrient levels GO:0031667 370 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.035
cell migration GO:0016477 197 0.035
intracellular signal transduction GO:0035556 314 0.035
regulation of cell proliferation GO:0042127 359 0.035
organic acid metabolic process GO:0006082 292 0.035
cellular component movement GO:0006928 248 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
cellular component assembly GO:0022607 360 0.033
Rat Fly
carbohydrate derivative metabolic process GO:1901135 346 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
anterior posterior pattern specification GO:0009952 1 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
response to growth factor GO:0070848 189 0.030
response to acid chemical GO:0001101 222 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
regulation of cellular component organization GO:0051128 368 0.029
Rat
positive regulation of cell proliferation GO:0008284 249 0.029
response to decreased oxygen levels GO:0036293 237 0.029
Rat
anatomical structure morphogenesis GO:0009653 298 0.028
Rat Fly
positive regulation of transcription dna templated GO:0045893 197 0.028
protein complex subunit organization GO:0071822 302 0.028
carboxylic acid metabolic process GO:0019752 289 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
single organism biosynthetic process GO:0044711 342 0.027
positive regulation of rna metabolic process GO:0051254 203 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
cellular homeostasis GO:0019725 252 0.026
locomotion GO:0040011 237 0.025
cellular component biogenesis GO:0044085 368 0.025
Rat Fly
regulation of cellular amine metabolic process GO:0033238 8 0.024
regulation of cellular component movement GO:0051270 150 0.024
protein complex assembly GO:0006461 263 0.024
oxoacid metabolic process GO:0043436 290 0.023
regulation of molecular function GO:0065009 398 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
regulation of cell development GO:0060284 263 0.023
Rat
purine containing compound metabolic process GO:0072521 253 0.023
single organism catabolic process GO:0044712 283 0.023
defense response GO:0006952 194 0.023
single organism reproductive process GO:0044702 297 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleotide metabolic process GO:0009117 279 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
cellular chemical homeostasis GO:0055082 247 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
catabolic process GO:0009056 351 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
divalent inorganic cation transport GO:0072511 134 0.020
negative regulation of gene expression GO:0010629 199 0.020
calcium ion homeostasis GO:0055074 162 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
cellular amine metabolic process GO:0044106 38 0.020
protein complex biogenesis GO:0070271 263 0.020
cation homeostasis GO:0055080 195 0.020
organelle organization GO:0006996 266 0.020
Mouse Fly
cellular response to stress GO:0033554 269 0.020
reproductive process GO:0022414 372 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
amine metabolic process GO:0009308 38 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
cardiovascular system development GO:0072358 134 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
actin filament based process GO:0030029 86 0.019
Mouse Fly
single organism organelle organization GO:1902589 180 0.019
Mouse Fly
divalent inorganic cation homeostasis GO:0072507 165 0.019
cell projection organization GO:0030030 302 0.019
Rat
blood circulation GO:0008015 183 0.019
circulatory system process GO:0003013 183 0.019
neuron projection development GO:0031175 273 0.019
Rat
cellular response to nitrogen compound GO:1901699 210 0.018
secretion GO:0046903 307 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
muscle structure development GO:0061061 87 0.018
Fly
ras protein signal transduction GO:0007265 29 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of cell projection organization GO:0031344 175 0.018
Rat
aromatic compound catabolic process GO:0019439 168 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
neuron differentiation GO:0030182 368 0.017
Rat
multicellular organismal reproductive process GO:0048609 233 0.017
multi organism reproductive process GO:0044703 262 0.017
regulation of apoptotic process GO:0042981 335 0.017
axis specification GO:0009798 4 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
neuron projection morphogenesis GO:0048812 122 0.017
Rat
immune system process GO:0002376 204 0.017
cell morphogenesis GO:0000902 142 0.017
Rat
response to nutrient GO:0007584 248 0.017
response to oxygen levels GO:0070482 265 0.017
Rat
macromolecular complex subunit organization GO:0043933 339 0.017
organophosphate biosynthetic process GO:0090407 143 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
establishment of tissue polarity GO:0007164 2 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
muscle system process GO:0003012 115 0.016
heart development GO:0007507 72 0.016
positive regulation of developmental process GO:0051094 283 0.016
neurological system process GO:0050877 219 0.016
regulation of system process GO:0044057 208 0.016
positive regulation of molecular function GO:0044093 230 0.016
regulation of catalytic activity GO:0050790 304 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
programmed cell death GO:0012501 392 0.016
ion homeostasis GO:0050801 212 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.016
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cardiac chamber development GO:0003205 1 0.016
nucleoside metabolic process GO:0009116 179 0.016
cytoskeleton organization GO:0007010 111 0.016
Mouse Fly
apoptotic process GO:0006915 381 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
negative regulation of metabolic process GO:0009892 331 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
regeneration GO:0031099 163 0.015
regulation of programmed cell death GO:0043067 341 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of cell communication GO:0010647 271 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of neuron differentiation GO:0045664 208 0.015
Rat
cellular response to extracellular stimulus GO:0031668 73 0.015
aging GO:0007568 241 0.015
response to estrogen GO:0043627 232 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
regulation of nervous system development GO:0051960 264 0.014
Rat
cellular ketone metabolic process GO:0042180 51 0.014
regulation of neurogenesis GO:0050767 247 0.014
Rat
neuron development GO:0048666 286 0.014
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
cellular catabolic process GO:0044248 295 0.014
circulatory system development GO:0072359 134 0.014
homeostatic process GO:0042592 331 0.014
neuronal action potential GO:0019228 35 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
positive regulation of nervous system development GO:0051962 178 0.014
cell motility GO:0048870 202 0.014
actin cytoskeleton organization GO:0030036 73 0.014
Mouse Fly
cellular calcium ion homeostasis GO:0006874 160 0.014
organic substance catabolic process GO:1901575 316 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
organophosphate metabolic process GO:0019637 370 0.014
gland development GO:0048732 155 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cellular response to external stimulus GO:0071496 118 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of cell death GO:0060548 229 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
embryonic pattern specification GO:0009880 1 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
Rat
response to inorganic substance GO:0010035 377 0.013
carbohydrate homeostasis GO:0033500 75 0.013
central nervous system development GO:0007417 311 0.013
proteolysis GO:0006508 175 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
Rat
brain development GO:0007420 247 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to oxidative stress GO:0006979 186 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of locomotion GO:0040012 148 0.013
response to ketone GO:1901654 182 0.012
cellular component morphogenesis GO:0032989 155 0.012
Rat Fly
cellular cation homeostasis GO:0030003 180 0.012
positive regulation of cell development GO:0010720 176 0.012
transmission of nerve impulse GO:0019226 42 0.012
response to glucose GO:0009749 136 0.012
response to hypoxia GO:0001666 231 0.012
Rat
inflammatory response GO:0006954 150 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
female pregnancy GO:0007565 122 0.012
reproduction GO:0000003 245 0.012
response to hexose GO:0009746 144 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
positive regulation of cell death GO:0010942 184 0.012
regulation of cell migration GO:0030334 128 0.012
negative regulation of cell communication GO:0010648 158 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
cardiac ventricle development GO:0003231 1 0.012
metal ion transport GO:0030001 289 0.012
cardiac muscle contraction GO:0060048 27 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
regulation of phosphorylation GO:0042325 248 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
calcium ion transport GO:0006816 131 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
cellular response to peptide GO:1901653 133 0.011
regulation of protein metabolic process GO:0051246 289 0.011
response to metal ion GO:0010038 253 0.011
cellular ion homeostasis GO:0006873 184 0.011
adult locomotory behavior GO:0008344 4 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
cation transport GO:0006812 382 0.011
response to monosaccharide GO:0034284 159 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
Rat
glucose homeostasis GO:0042593 75 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
secretion by cell GO:0032940 248 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
regulation of blood circulation GO:1903522 110 0.011
heart process GO:0003015 57 0.011
regulation of signal transduction GO:0009966 318 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to nutrient levels GO:0031669 60 0.011
cell growth GO:0016049 104 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
behavior GO:0007610 205 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
regulation of muscle system process GO:0090257 79 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
cellular response to alcohol GO:0097306 87 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of neuron projection development GO:0010975 161 0.010
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
Fly
regulation of secretion by cell GO:1903530 208 0.010
cellular response to lipid GO:0071396 201 0.010
protein oligomerization GO:0051259 191 0.010
regulation of establishment of planar polarity GO:0090175 2 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
regulation of catabolic process GO:0009894 113 0.010

Pdlim7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.014
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011