Rattus norvegicus

0 known processes

Pcsk7

proprotein convertase subtilisin/kexin type 7

(Aliases: PC7)

Pcsk7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to lipopolysaccharide GO:0032496 191 0.162
Rat
response to other organism GO:0051707 220 0.139
Rat
response to external biotic stimulus GO:0043207 221 0.136
Rat
response to nutrient levels GO:0031667 370 0.118
Rat
defense response GO:0006952 194 0.115
response to biotic stimulus GO:0009607 226 0.099
Rat
response to inorganic substance GO:0010035 377 0.097
Rat
cellular amino acid metabolic process GO:0006520 107 0.097
response to bacterium GO:0009617 200 0.089
Rat
regulation of molecular function GO:0065009 398 0.088
regulation of phosphate metabolic process GO:0019220 349 0.088
organophosphate metabolic process GO:0019637 370 0.082
nucleobase containing small molecule metabolic process GO:0055086 316 0.080
response to extracellular stimulus GO:0009991 380 0.074
Rat
nitrogen compound transport GO:0071705 229 0.073
carboxylic acid metabolic process GO:0019752 289 0.070
regulation of transcription dna templated GO:0006355 374 0.070
nucleoside phosphate metabolic process GO:0006753 283 0.069
purine containing compound metabolic process GO:0072521 253 0.069
response to oxidative stress GO:0006979 186 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
positive regulation of gene expression GO:0010628 244 0.067
cellular response to oxygen containing compound GO:1901701 386 0.066
cellular catabolic process GO:0044248 295 0.066
regulation of nucleic acid templated transcription GO:1903506 380 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.065
nucleotide metabolic process GO:0009117 279 0.065
regulation of rna biosynthetic process GO:2001141 381 0.062
response to peptide hormone GO:0043434 278 0.061
Rat
positive regulation of biosynthetic process GO:0009891 319 0.060
cellular response to stress GO:0033554 269 0.060
positive regulation of transcription dna templated GO:0045893 197 0.060
cell cell signaling GO:0007267 335 0.059
proteolysis GO:0006508 175 0.059
Human Rat
organic acid metabolic process GO:0006082 292 0.058
regulation of signal transduction GO:0009966 318 0.057
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.057
ribonucleotide metabolic process GO:0009259 231 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
cellular response to endogenous stimulus GO:0071495 377 0.057
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.056
organelle organization GO:0006996 266 0.055
positive regulation of rna metabolic process GO:0051254 203 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.051
anatomical structure morphogenesis GO:0009653 298 0.051
macromolecular complex subunit organization GO:0043933 339 0.051
glycosyl compound metabolic process GO:1901657 182 0.049
nucleic acid templated transcription GO:0097659 379 0.049
response to hypoxia GO:0001666 231 0.049
regulation of protein metabolic process GO:0051246 289 0.049
positive regulation of transport GO:0051050 245 0.049
Rat
intracellular signal transduction GO:0035556 314 0.048
cellular component assembly GO:0022607 360 0.048
positive regulation of cellular biosynthetic process GO:0031328 295 0.048
negative regulation of signaling GO:0023057 157 0.047
purine nucleotide metabolic process GO:0006163 229 0.047
positive regulation of response to stimulus GO:0048584 285 0.047
Rat
secretion GO:0046903 307 0.047
Rat
cellular amine metabolic process GO:0044106 38 0.046
regulation of cell differentiation GO:0045595 320 0.046
organophosphate biosynthetic process GO:0090407 143 0.045
single organism biosynthetic process GO:0044711 342 0.045
oxoacid metabolic process GO:0043436 290 0.045
organic substance catabolic process GO:1901575 316 0.044
nucleoside triphosphate metabolic process GO:0009141 144 0.044
amine metabolic process GO:0009308 38 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
purine nucleoside triphosphate metabolic process GO:0009144 141 0.042
purine ribonucleotide metabolic process GO:0009150 227 0.042
reproduction GO:0000003 245 0.041
immune system process GO:0002376 204 0.041
cellular response to cytokine stimulus GO:0071345 127 0.041
ribonucleoside metabolic process GO:0009119 174 0.041
transcription dna templated GO:0006351 377 0.041
macromolecular complex assembly GO:0065003 273 0.041
aging GO:0007568 241 0.041
Rat
response to oxygen levels GO:0070482 265 0.040
blood circulation GO:0008015 183 0.040
ribose phosphate metabolic process GO:0019693 235 0.039
response to reactive oxygen species GO:0000302 120 0.039
negative regulation of gene expression GO:0010629 199 0.038
reproductive process GO:0022414 372 0.038
catabolic process GO:0009056 351 0.038
rna metabolic process GO:0016070 406 0.038
inflammatory response GO:0006954 150 0.038
response to cytokine GO:0034097 215 0.038
Rat
purine nucleoside metabolic process GO:0042278 169 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.038
protein complex biogenesis GO:0070271 263 0.038
single organism intracellular transport GO:1902582 166 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
organonitrogen compound biosynthetic process GO:1901566 167 0.037
response to decreased oxygen levels GO:0036293 237 0.037
protein phosphorylation GO:0006468 345 0.037
negative regulation of cell communication GO:0010648 158 0.037
homeostatic process GO:0042592 331 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.036
regulation of cellular component organization GO:0051128 368 0.036
monocarboxylic acid metabolic process GO:0032787 152 0.036
regulation of cellular localization GO:0060341 263 0.035
Rat
immune response GO:0006955 104 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
transmembrane transport GO:0055085 412 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
response to purine containing compound GO:0014074 126 0.034
cellular component biogenesis GO:0044085 368 0.034
lipid metabolic process GO:0006629 283 0.034
regulation of response to external stimulus GO:0032101 106 0.034
ribonucleotide catabolic process GO:0009261 136 0.034
purine nucleotide biosynthetic process GO:0006164 83 0.034
positive regulation of cell death GO:0010942 184 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
regulation of cell development GO:0060284 263 0.033
protein oligomerization GO:0051259 191 0.033
multicellular organism reproduction GO:0032504 233 0.033
synaptic transmission GO:0007268 235 0.033
chemical homeostasis GO:0048878 292 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.032
negative regulation of metabolic process GO:0009892 331 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
programmed cell death GO:0012501 392 0.032
regulation of programmed cell death GO:0043067 341 0.032
cytokine mediated signaling pathway GO:0019221 43 0.032
cellular component movement GO:0006928 248 0.031
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.031
positive regulation of molecular function GO:0044093 230 0.031
nucleoside metabolic process GO:0009116 179 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
purine ribonucleotide catabolic process GO:0009154 136 0.031
response to molecule of bacterial origin GO:0002237 194 0.031
Rat
mapk cascade GO:0000165 140 0.031
positive regulation of signaling GO:0023056 270 0.031
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
macromolecule localization GO:0033036 252 0.030
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.030
rna biosynthetic process GO:0032774 380 0.030
multi organism reproductive process GO:0044703 262 0.030
regulation of phosphorylation GO:0042325 248 0.029
response to glucocorticoid GO:0051384 223 0.029
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.029
multicellular organism growth GO:0035264 1 0.029
response to insulin GO:0032868 133 0.029
response to monosaccharide GO:0034284 159 0.029
Rat
endocytosis GO:0006897 84 0.029
locomotion GO:0040011 237 0.029
Rat
regulation of catalytic activity GO:0050790 304 0.029
multicellular organismal reproductive process GO:0048609 233 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
nucleotide biosynthetic process GO:0009165 98 0.028
metal ion homeostasis GO:0055065 186 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
cellular ketone metabolic process GO:0042180 51 0.028
response to peptide GO:1901652 292 0.028
Rat
signal release GO:0023061 145 0.028
single organism reproductive process GO:0044702 297 0.028
response to hydrogen peroxide GO:0042542 89 0.028
regulation of defense response GO:0031347 68 0.028
regulation of apoptotic process GO:0042981 335 0.027
neuron differentiation GO:0030182 368 0.027
single organism catabolic process GO:0044712 283 0.027
regulation of mesenchymal cell proliferation GO:0010464 4 0.027
protein complex subunit organization GO:0071822 302 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
single organism organelle organization GO:1902589 180 0.027
tissue development GO:0009888 252 0.027
regulation of system process GO:0044057 208 0.027
small gtpase mediated signal transduction GO:0007264 36 0.026
regulation of secretion GO:0051046 224 0.026
Rat
intracellular transport GO:0046907 185 0.026
negative regulation of metanephros development GO:0072217 2 0.026
response to nutrient GO:0007584 248 0.026
regulation of cytokine production GO:0001817 56 0.026
regulation of secretion by cell GO:1903530 208 0.026
Rat
cation transmembrane transport GO:0098655 263 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
response to organophosphorus GO:0046683 102 0.025
regulation of mapk cascade GO:0043408 116 0.025
regulation of response to stress GO:0080134 126 0.025
negative regulation of rna biosynthetic process GO:1902679 118 0.025
ribonucleotide biosynthetic process GO:0009260 85 0.025
protein complex assembly GO:0006461 263 0.025
central nervous system development GO:0007417 311 0.025
Rat
response to ketone GO:1901654 182 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
ion transmembrane transport GO:0034220 365 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
regulation of cell morphogenesis GO:0022604 77 0.023
neurological system process GO:0050877 219 0.023
response to metal ion GO:0010038 253 0.023
Rat
regulation of rna metabolic process GO:0051252 391 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
negative regulation of molecular function GO:0044092 133 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
cellular response to peptide GO:1901653 133 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
regulation of neurogenesis GO:0050767 247 0.023
response to amino acid GO:0043200 75 0.023
purine nucleoside triphosphate catabolic process GO:0009146 122 0.023
positive regulation of cell development GO:0010720 176 0.023
cellular response to reactive oxygen species GO:0034614 55 0.022
cellular lipid metabolic process GO:0044255 208 0.022
female pregnancy GO:0007565 122 0.022
response to acid chemical GO:0001101 222 0.022
Rat
positive regulation of phosphorylation GO:0042327 177 0.022
cellular response to tumor necrosis factor GO:0071356 46 0.022
cellular ion homeostasis GO:0006873 184 0.022
positive regulation of signal transduction GO:0009967 175 0.022
Rat
organophosphate catabolic process GO:0046434 148 0.022
regulation of nervous system development GO:0051960 264 0.022
circulatory system process GO:0003013 183 0.022
regulation of hydrolase activity GO:0051336 143 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
lipid localization GO:0010876 62 0.021
response to growth factor GO:0070848 189 0.021
Rat
organ morphogenesis GO:0009887 75 0.021
positive regulation of secretion GO:0051047 140 0.021
Rat
positive regulation of cell differentiation GO:0045597 217 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.021
rhythmic process GO:0048511 156 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
apoptotic process GO:0006915 381 0.021
regulation of cellular component movement GO:0051270 150 0.021
Rat
positive regulation of developmental process GO:0051094 283 0.020
negative regulation of cell death GO:0060548 229 0.020
calcium ion homeostasis GO:0055074 162 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
neuron development GO:0048666 286 0.020
acute inflammatory response GO:0002526 58 0.020
ras protein signal transduction GO:0007265 29 0.020
response to radiation GO:0009314 137 0.020
gland development GO:0048732 155 0.020
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
response to tumor necrosis factor GO:0034612 56 0.019
ion homeostasis GO:0050801 212 0.019
mesenchymal cell proliferation GO:0010463 4 0.019
regulation of protein localization GO:0032880 81 0.019
Rat
regulation of cell proliferation GO:0042127 359 0.019
organic anion transport GO:0015711 132 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
cell projection organization GO:0030030 302 0.019
neuron projection development GO:0031175 273 0.019
growth GO:0040007 165 0.018
peptidyl amino acid modification GO:0018193 126 0.018
hormone transport GO:0009914 121 0.018
single organism membrane organization GO:0044802 74 0.018
purine containing compound catabolic process GO:0072523 138 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
regulation of protein modification process GO:0031399 194 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
protein localization GO:0008104 191 0.017
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
circulatory system development GO:0072359 134 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
nucleoside catabolic process GO:0009164 126 0.017
response to ammonium ion GO:0060359 71 0.017
Rat
positive regulation of programmed cell death GO:0043068 157 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of catabolic process GO:0009894 113 0.017
vesicle mediated transport GO:0016192 181 0.017
small molecule biosynthetic process GO:0044283 124 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.017
b cell differentiation GO:0030183 2 0.017
regulation of blood circulation GO:1903522 110 0.017
cation transport GO:0006812 382 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
negative regulation of innate immune response GO:0045824 4 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
response to alkaloid GO:0043279 132 0.016
Rat
cellular protein localization GO:0034613 122 0.016
positive regulation of catabolic process GO:0009896 78 0.016
fatty acid metabolic process GO:0006631 99 0.016
cation homeostasis GO:0055080 195 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of gtpase activity GO:0043087 57 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
regulation of immune response GO:0050776 55 0.016
heterocycle catabolic process GO:0046700 167 0.016
dna metabolic process GO:0006259 96 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of cell communication GO:0010647 271 0.016
Rat
negative regulation of cell development GO:0010721 82 0.016
protein transport GO:0015031 132 0.016
Rat
positive regulation of cellular component organization GO:0051130 200 0.016
leukocyte activation GO:0045321 76 0.016
secretion by cell GO:0032940 248 0.016
Rat
development of primary female sexual characteristics GO:0046545 56 0.016
positive regulation of protein modification process GO:0031401 142 0.016
nucleotide catabolic process GO:0009166 139 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
b cell activation involved in immune response GO:0002312 1 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to camp GO:0051591 91 0.015
cellular response to oxidative stress GO:0034599 76 0.015
immunoglobulin mediated immune response GO:0016064 4 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
protein processing GO:0016485 68 0.015
Human Rat
nucleoside monophosphate metabolic process GO:0009123 93 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
Rat
response to wounding GO:0009611 254 0.015
Rat
defense response to gram negative bacterium GO:0050829 3 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
negative regulation of response to external stimulus GO:0032102 37 0.015
metal ion transport GO:0030001 289 0.015
regulation of immune system process GO:0002682 123 0.015
negative regulation of signal transduction GO:0009968 83 0.015
cell differentiation involved in kidney development GO:0061005 4 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.014
cellular chemical homeostasis GO:0055082 247 0.014
hormone secretion GO:0046879 115 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
epithelial cell differentiation involved in kidney development GO:0035850 3 0.014
cell morphogenesis GO:0000902 142 0.014
establishment of protein localization GO:0045184 141 0.014
Rat
negative regulation of cellular component organization GO:0051129 83 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of nervous system development GO:0051962 178 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
gtp catabolic process GO:0006184 71 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
regulation of response to wounding GO:1903034 69 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
regulation of hormone secretion GO:0046883 106 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
response to estrogen GO:0043627 232 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
lipid storage GO:0019915 1 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
oxidation reduction process GO:0055114 304 0.014
divalent metal ion transport GO:0070838 132 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
multi multicellular organism process GO:0044706 138 0.014
regulation of metanephros development GO:0072215 4 0.014
regulation of hormone levels GO:0010817 187 0.014
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
developmental growth GO:0048589 100 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
regulation of transferase activity GO:0051338 123 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
gtp metabolic process GO:0046039 72 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.013
cell growth GO:0016049 104 0.013
organic hydroxy compound transport GO:0015850 77 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
mesenchymal to epithelial transition GO:0060231 3 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
response to carbohydrate GO:0009743 183 0.013
Rat
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of neuron death GO:1901214 115 0.013
regulation of nephron tubule epithelial cell differentiation GO:0072182 1 0.013
cellular homeostasis GO:0019725 252 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to ethanol GO:0045471 162 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
Rat
metanephric tubule development GO:0072170 4 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
cell activation GO:0001775 97 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
innate immune response GO:0045087 35 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of protein kinase activity GO:0045859 105 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
spindle organization GO:0007051 2 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
aromatic compound catabolic process GO:0019439 168 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
calcium ion transport GO:0006816 131 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
localization of cell GO:0051674 202 0.012
Rat
positive regulation of atp biosynthetic process GO:2001171 2 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
regulation of atp biosynthetic process GO:2001169 2 0.012
amide transport GO:0042886 105 0.012
axis specification GO:0009798 4 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of immune system process GO:0002684 90 0.012
regulation of anatomical structure size GO:0090066 135 0.012
reproductive system development GO:0061458 128 0.012
atp metabolic process GO:0046034 72 0.012
cytokine biosynthetic process GO:0042089 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.012
cofactor metabolic process GO:0051186 95 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
regulation of cytokine biosynthetic process GO:0042035 3 0.011
neuronal action potential GO:0019228 35 0.011
embryonic pattern specification GO:0009880 1 0.011
regulation of body fluid levels GO:0050878 90 0.011
regulation of neurotransmitter levels GO:0001505 42 0.011
coenzyme metabolic process GO:0006732 86 0.011
membrane organization GO:0061024 94 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
anion transport GO:0006820 178 0.011
regulation of synaptic transmission GO:0050804 141 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
positive regulation of immune response GO:0050778 42 0.011
response to hexose GO:0009746 144 0.011
Rat
positive regulation of isotype switching GO:0045830 1 0.011
chromosome segregation GO:0007059 2 0.011
skeletal muscle satellite cell proliferation GO:0014841 1 0.011
organic acid catabolic process GO:0016054 49 0.011
protein homooligomerization GO:0051260 91 0.011
sensory perception GO:0007600 101 0.011
negative regulation of secretion GO:0051048 82 0.011
regulation of satellite cell proliferation GO:0014842 1 0.011
regulation of inflammatory response GO:0050727 48 0.011
tube development GO:0035295 89 0.011
behavior GO:0007610 205 0.011
response to corticosteroid GO:0031960 235 0.011
Rat
reproductive structure development GO:0048608 128 0.011
regulation of ras protein signal transduction GO:0046578 45 0.011
cell cycle checkpoint GO:0000075 2 0.011
regulation of innate immune response GO:0045088 15 0.011
response to toxic substance GO:0009636 133 0.011
regulation of telomerase activity GO:0051972 2 0.011
regulation of hydrogen peroxide biosynthetic process GO:0010728 2 0.011
lipid biosynthetic process GO:0008610 128 0.011
regulation of ion transport GO:0043269 245 0.011
gliogenesis GO:0042063 93 0.011
cell migration GO:0016477 197 0.011
Rat
positive regulation of cell projection organization GO:0031346 111 0.011
muscle system process GO:0003012 115 0.011
neurotransmitter transport GO:0006836 42 0.011
mesenchymal cell differentiation involved in renal system development GO:2001012 1 0.011
female gonad development GO:0008585 53 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
transmission of nerve impulse GO:0019226 42 0.011
positive regulation of ion transport GO:0043270 94 0.011
cellular macromolecule localization GO:0070727 122 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
jak stat cascade GO:0007259 26 0.010
regulation of calcium ion transport GO:0051924 77 0.010
glial cell differentiation GO:0010001 65 0.010
anterior posterior pattern specification GO:0009952 1 0.010

Pcsk7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.016
gastrointestinal system cancer DOID:3119 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
eye and adnexa disease DOID:1492 0 0.012
disease of metabolism DOID:0014667 0 0.012
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
intestinal cancer DOID:10155 0 0.011
colorectal cancer DOID:9256 0 0.011
central nervous system disease DOID:331 0 0.011