Rattus norvegicus

0 known processes

Pcsk5

proprotein convertase subtilisin/kexin type 5

(Aliases: Pc5)

Pcsk5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 248 0.285
Rat
intracellular signal transduction GO:0035556 314 0.271
response to oxygen levels GO:0070482 265 0.242
regulation of signal transduction GO:0009966 318 0.213
Rat
positive regulation of response to stimulus GO:0048584 285 0.202
Rat
cellular component biogenesis GO:0044085 368 0.199
cellular response to endogenous stimulus GO:0071495 377 0.187
Rat
positive regulation of signaling GO:0023056 270 0.185
Rat
cellular component assembly GO:0022607 360 0.160
protein complex subunit organization GO:0071822 302 0.131
cellular response to peptide hormone stimulus GO:0071375 120 0.130
cell motility GO:0048870 202 0.124
Rat
protein localization GO:0008104 191 0.123
Human Rat
programmed cell death GO:0012501 392 0.120
apoptotic process GO:0006915 381 0.119
mesoderm development GO:0007498 2 0.117
cellular catabolic process GO:0044248 295 0.116
signal transduction by phosphorylation GO:0023014 144 0.115
single organism biosynthetic process GO:0044711 342 0.113
catabolic process GO:0009056 351 0.110
positive regulation of developmental process GO:0051094 283 0.110
response to corticosteroid GO:0031960 235 0.109
Rat
cellular response to hormone stimulus GO:0032870 247 0.109
aging GO:0007568 241 0.108
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.105
positive regulation of cellular component movement GO:0051272 102 0.104
Rat
response to hypoxia GO:0001666 231 0.104
positive regulation of cell communication GO:0010647 271 0.103
Rat
response to decreased oxygen levels GO:0036293 237 0.103
gastrulation GO:0007369 2 0.100
organophosphate metabolic process GO:0019637 370 0.100
macromolecule localization GO:0033036 252 0.099
Human Rat
positive regulation of multicellular organismal process GO:0051240 387 0.097
cellular lipid metabolic process GO:0044255 208 0.093
regulation of intracellular signal transduction GO:1902531 218 0.092
reproduction GO:0000003 245 0.090
single organism reproductive process GO:0044702 297 0.090
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.089
tissue development GO:0009888 252 0.088
macromolecular complex assembly GO:0065003 273 0.087
positive regulation of cellular protein metabolic process GO:0032270 167 0.086
mapk cascade GO:0000165 140 0.085
response to glucocorticoid GO:0051384 223 0.082
Rat
positive regulation of signal transduction GO:0009967 175 0.081
Rat
regulation of phosphate metabolic process GO:0019220 349 0.079
regulation of cellular component movement GO:0051270 150 0.078
Rat
cell cell signaling GO:0007267 335 0.078
regulation of locomotion GO:0040012 148 0.078
Rat
response to inorganic substance GO:0010035 377 0.078
Rat
oxoacid metabolic process GO:0043436 290 0.077
regulation of cellular ketone metabolic process GO:0010565 27 0.076
response to estrogen GO:0043627 232 0.076
growth GO:0040007 165 0.076
protein phosphorylation GO:0006468 345 0.075
cellular response to growth factor stimulus GO:0071363 162 0.075
Rat
positive regulation of phosphorylation GO:0042327 177 0.074
regulation of apoptotic process GO:0042981 335 0.073
organic acid metabolic process GO:0006082 292 0.072
reproductive process GO:0022414 372 0.072
Mouse
regulation of phosphorylation GO:0042325 248 0.072
regulation of molecular function GO:0065009 398 0.071
multicellular organism reproduction GO:0032504 233 0.071
carboxylic acid metabolic process GO:0019752 289 0.070
response to temperature stimulus GO:0009266 94 0.069
regulation of cellular protein metabolic process GO:0032268 267 0.069
positive regulation of apoptotic process GO:0043065 154 0.068
homeostatic process GO:0042592 331 0.067
taxis GO:0042330 67 0.067
response to peptide GO:1901652 292 0.067
Rat
regulation of protein kinase activity GO:0045859 105 0.067
regulation of protein modification process GO:0031399 194 0.067
wound healing GO:0042060 122 0.066
regulation of cell proliferation GO:0042127 359 0.065
protein complex assembly GO:0006461 263 0.064
carbohydrate derivative metabolic process GO:1901135 346 0.064
cellular response to insulin stimulus GO:0032869 81 0.064
positive regulation of protein metabolic process GO:0051247 178 0.064
regulation of anatomical structure size GO:0090066 135 0.063
positive regulation of protein transport GO:0051222 41 0.063
Rat
ossification GO:0001503 70 0.063
regulation of phosphorus metabolic process GO:0051174 349 0.063
organic substance catabolic process GO:1901575 316 0.063
central nervous system development GO:0007417 311 0.063
Rat
response to nutrient GO:0007584 248 0.063
anatomical structure morphogenesis GO:0009653 298 0.063
Mouse
regulation of catalytic activity GO:0050790 304 0.061
locomotion GO:0040011 237 0.061
Rat
cellular response to stress GO:0033554 269 0.061
regulation of programmed cell death GO:0043067 341 0.061
localization of cell GO:0051674 202 0.060
Rat
regulation of tube size GO:0035150 89 0.060
protein autophosphorylation GO:0046777 66 0.060
macromolecular complex subunit organization GO:0043933 339 0.060
heart morphogenesis GO:0003007 3 0.059
purine containing compound metabolic process GO:0072521 253 0.059
cellular response to organonitrogen compound GO:0071417 197 0.059
cell growth GO:0016049 104 0.059
neuron differentiation GO:0030182 368 0.058
response to estradiol GO:0032355 164 0.058
regulation of protein metabolic process GO:0051246 289 0.058
regulation of map kinase activity GO:0043405 53 0.058
response to extracellular stimulus GO:0009991 380 0.057
Rat
neuron development GO:0048666 286 0.057
biological adhesion GO:0022610 110 0.056
regeneration GO:0031099 163 0.056
regulation of protein phosphorylation GO:0001932 183 0.055
blood circulation GO:0008015 183 0.054
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.054
cellular amino acid metabolic process GO:0006520 107 0.054
multi organism reproductive process GO:0044703 262 0.054
Mouse
synaptic transmission GO:0007268 235 0.053
establishment of protein localization GO:0045184 141 0.053
Human Rat
anterior posterior pattern specification GO:0009952 1 0.053
Human Mouse
response to ketone GO:1901654 182 0.052
regulation of cellular localization GO:0060341 263 0.052
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
positive regulation of mapk cascade GO:0043410 92 0.052
cellular response to organic cyclic compound GO:0071407 202 0.051
negative regulation of cell death GO:0060548 229 0.051
rhythmic process GO:0048511 156 0.051
cellular component morphogenesis GO:0032989 155 0.050
regulation of mapk cascade GO:0043408 116 0.050
developmental growth GO:0048589 100 0.050
purine nucleotide metabolic process GO:0006163 229 0.050
formation of primary germ layer GO:0001704 1 0.050
defense response GO:0006952 194 0.049
response to oxidative stress GO:0006979 186 0.049
regulation of system process GO:0044057 208 0.048
positive regulation of catalytic activity GO:0043085 184 0.048
cell projection organization GO:0030030 302 0.048
response to lipopolysaccharide GO:0032496 191 0.048
Rat
regulation of cell migration GO:0030334 128 0.048
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.048
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.048
vascular process in circulatory system GO:0003018 96 0.047
cellular carbohydrate metabolic process GO:0044262 72 0.047
reactive oxygen species metabolic process GO:0072593 37 0.047
negative regulation of programmed cell death GO:0043069 183 0.046
organonitrogen compound catabolic process GO:1901565 179 0.046
nucleoside phosphate metabolic process GO:0006753 283 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.045
single organism catabolic process GO:0044712 283 0.045
neuron projection development GO:0031175 273 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.045
amine metabolic process GO:0009308 38 0.044
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.044
positive regulation of programmed cell death GO:0043068 157 0.043
cellular response to peptide GO:1901653 133 0.043
behavior GO:0007610 205 0.043
developmental process involved in reproduction GO:0003006 159 0.043
actin filament based process GO:0030029 86 0.042
secretion GO:0046903 307 0.042
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.042
regulation of kinase activity GO:0043549 117 0.042
protein oligomerization GO:0051259 191 0.042
cardiovascular system development GO:0072358 134 0.041
Mouse
response to insulin GO:0032868 133 0.040
reproductive system development GO:0061458 128 0.040
protein complex biogenesis GO:0070271 263 0.040
positive regulation of protein phosphorylation GO:0001934 135 0.040
single organism organelle organization GO:1902589 180 0.039
positive regulation of intracellular signal transduction GO:1902533 138 0.039
nucleoside monophosphate metabolic process GO:0009123 93 0.039
embryo development GO:0009790 49 0.039
Human Mouse
positive regulation of protein modification process GO:0031401 142 0.039
response to wounding GO:0009611 254 0.039
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.039
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
cellular response to corticosteroid stimulus GO:0071384 69 0.039
chemical homeostasis GO:0048878 292 0.038
ras protein signal transduction GO:0007265 29 0.038
response to growth factor GO:0070848 189 0.038
Rat
regulation of cell differentiation GO:0045595 320 0.038
muscle cell proliferation GO:0033002 84 0.038
response to metal ion GO:0010038 253 0.038
Rat
response to biotic stimulus GO:0009607 226 0.037
Rat
positive regulation of transport GO:0051050 245 0.037
Rat
cellular response to nitrogen compound GO:1901699 210 0.037
positive regulation of molecular function GO:0044093 230 0.037
cellular chemical homeostasis GO:0055082 247 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
regulation of transferase activity GO:0051338 123 0.036
neuron projection morphogenesis GO:0048812 122 0.036
negative regulation of response to stimulus GO:0048585 155 0.036
regulation of cell motility GO:2000145 131 0.036
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
regulation of cell development GO:0060284 263 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
negative regulation of metabolic process GO:0009892 331 0.035
dna metabolic process GO:0006259 96 0.035
positive regulation of transferase activity GO:0051347 81 0.035
circulatory system process GO:0003013 183 0.035
Human
ion homeostasis GO:0050801 212 0.034
nucleotide metabolic process GO:0009117 279 0.034
negative regulation of signaling GO:0023057 157 0.034
cellular homeostasis GO:0019725 252 0.034
organ morphogenesis GO:0009887 75 0.033
purine nucleoside monophosphate metabolic process GO:0009126 84 0.033
positive regulation of cell death GO:0010942 184 0.033
rna metabolic process GO:0016070 406 0.033
neurological system process GO:0050877 219 0.033
regulation of protein localization GO:0032880 81 0.033
Rat
transcription dna templated GO:0006351 377 0.033
response to nutrient levels GO:0031667 370 0.032
Rat
ribonucleotide metabolic process GO:0009259 231 0.032
positive regulation of protein kinase activity GO:0045860 73 0.032
circulatory system development GO:0072359 134 0.032
Mouse
response to dexamethasone GO:0071548 49 0.032
cation transport GO:0006812 382 0.032
brain development GO:0007420 247 0.032
Rat
purine nucleotide biosynthetic process GO:0006164 83 0.032
cell morphogenesis GO:0000902 142 0.032
cellular amine metabolic process GO:0044106 38 0.032
nucleotide biosynthetic process GO:0009165 98 0.032
cognition GO:0050890 92 0.032
regulation of blood vessel size GO:0050880 89 0.031
organophosphate biosynthetic process GO:0090407 143 0.031
sexual reproduction GO:0019953 148 0.031
metal ion transport GO:0030001 289 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
cell type specific apoptotic process GO:0097285 134 0.031
transmembrane transport GO:0055085 412 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
regulation of muscle system process GO:0090257 79 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
response to carbohydrate GO:0009743 183 0.031
Rat
positive regulation of biosynthetic process GO:0009891 319 0.031
regulation of nervous system development GO:0051960 264 0.031
urogenital system development GO:0001655 78 0.030
Human Mouse
eye morphogenesis GO:0048592 4 0.030
skeletal muscle tissue development GO:0007519 31 0.030
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.030
positive regulation of cell motility GO:2000147 97 0.030
Rat
purine containing compound biosynthetic process GO:0072522 85 0.030
digestive system development GO:0055123 41 0.030
Human Mouse
positive regulation of kinase activity GO:0033674 77 0.030
maintenance of location GO:0051235 17 0.029
cellular ketone metabolic process GO:0042180 51 0.029
gamete generation GO:0007276 124 0.029
cell migration GO:0016477 197 0.029
Rat
learning or memory GO:0007611 90 0.029
positive regulation of long term synaptic potentiation GO:1900273 4 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
lipid metabolic process GO:0006629 283 0.029
regulation of smooth muscle cell proliferation GO:0048660 75 0.029
response to peptide hormone GO:0043434 278 0.029
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.028
single organism cellular localization GO:1902580 102 0.028
response to monosaccharide GO:0034284 159 0.028
Rat
ribose phosphate metabolic process GO:0019693 235 0.028
regulation of transcription dna templated GO:0006355 374 0.028
heart development GO:0007507 72 0.028
Mouse
carbohydrate metabolic process GO:0005975 130 0.028
vesicle mediated transport GO:0016192 181 0.028
heterocycle catabolic process GO:0046700 167 0.028
response to glucose GO:0009749 136 0.028
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.028
negative regulation of cell communication GO:0010648 158 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
response to heat GO:0009408 60 0.027
limb morphogenesis GO:0035108 4 0.027
Mouse
positive regulation of map kinase activity GO:0043406 46 0.027
head development GO:0060322 247 0.027
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cellular response to glucocorticoid stimulus GO:0071385 68 0.027
ion transmembrane transport GO:0034220 365 0.027
nucleoside triphosphate metabolic process GO:0009141 144 0.027
axon development GO:0061564 96 0.026
reproductive structure development GO:0048608 128 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
regulation of cellular component organization GO:0051128 368 0.026
positive regulation of locomotion GO:0040017 102 0.026
Rat
regulation of rna metabolic process GO:0051252 391 0.026
muscle system process GO:0003012 115 0.026
secretion by cell GO:0032940 248 0.026
Human Rat
mesoderm morphogenesis GO:0048332 1 0.026
regulation of protein serine threonine kinase activity GO:0071900 64 0.025
cellular macromolecule localization GO:0070727 122 0.025
motor neuron axon guidance GO:0008045 1 0.025
striated muscle tissue development GO:0014706 58 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
multicellular organism growth GO:0035264 1 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.025
immune system process GO:0002376 204 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
rna biosynthetic process GO:0032774 380 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
response to reactive oxygen species GO:0000302 120 0.024
negative regulation of molecular function GO:0044092 133 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
protein homooligomerization GO:0051260 91 0.024
positive regulation of cell proliferation GO:0008284 249 0.023
response to other organism GO:0051707 220 0.023
Rat
regulation of neurogenesis GO:0050767 247 0.023
organ regeneration GO:0031100 101 0.023
cellular response to lipid GO:0071396 201 0.023
positive regulation of cell development GO:0010720 176 0.023
gonad development GO:0008406 104 0.023
gland development GO:0048732 155 0.023
Rat
multi multicellular organism process GO:0044706 138 0.023
Mouse
camp metabolic process GO:0046058 63 0.023
liver development GO:0001889 90 0.023
axonogenesis GO:0007409 71 0.023
response to bacterium GO:0009617 200 0.023
Rat
regulation of protein transport GO:0051223 68 0.023
Rat
small molecule biosynthetic process GO:0044283 124 0.023
inflammatory response GO:0006954 150 0.023
cell cycle GO:0007049 101 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
embryonic skeletal system development GO:0048706 3 0.023
Human Mouse
regulation of nucleotide biosynthetic process GO:0030808 47 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
dephosphorylation GO:0016311 98 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
organic cyclic compound catabolic process GO:1901361 175 0.022
hormone transport GO:0009914 121 0.022
vasoconstriction GO:0042310 54 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
cellular response to external stimulus GO:0071496 118 0.022
regulation of response to stress GO:0080134 126 0.022
regulation of vasculature development GO:1901342 44 0.022
appendage morphogenesis GO:0035107 4 0.022
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
response to radiation GO:0009314 137 0.022
cellular ion homeostasis GO:0006873 184 0.021
cation homeostasis GO:0055080 195 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
regulation of membrane potential GO:0042391 110 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
response to ethanol GO:0045471 162 0.021
regulation of growth GO:0040008 105 0.021
chemosensory behavior GO:0007635 2 0.021
calcium ion homeostasis GO:0055074 162 0.021
cellular response to alcohol GO:0097306 87 0.021
organelle organization GO:0006996 266 0.021
regulation of cell adhesion GO:0030155 52 0.021
chromosome segregation GO:0007059 2 0.021
cytoskeleton organization GO:0007010 111 0.021
regulation of reactive oxygen species metabolic process GO:2000377 26 0.020
positive regulation of response to external stimulus GO:0032103 51 0.020
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of transport GO:0051051 136 0.020
chemotaxis GO:0006935 66 0.020
lipid biosynthetic process GO:0008610 128 0.020
digestive tract development GO:0048565 39 0.020
Human Mouse
regulation of rna biosynthetic process GO:2001141 381 0.020
regulation of small gtpase mediated signal transduction GO:0051056 48 0.020
response to alkaloid GO:0043279 132 0.020
Rat
regulation of secretion by cell GO:1903530 208 0.020
Rat
glycerolipid metabolic process GO:0046486 67 0.020
regulation of ion transport GO:0043269 245 0.020
regulation of cell growth GO:0001558 85 0.020
salivary gland development GO:0007431 3 0.020
hepaticobiliary system development GO:0061008 90 0.020
nucleic acid templated transcription GO:0097659 379 0.020
regulation of homeostatic process GO:0032844 101 0.020
cell adhesion GO:0007155 110 0.020
embryonic pattern specification GO:0009880 1 0.020
regulation of vasoconstriction GO:0019229 44 0.019
protein transport GO:0015031 132 0.019
Human Rat
negative regulation of signal transduction GO:0009968 83 0.019
skeletal system development GO:0001501 41 0.019
Human Mouse
phospholipid metabolic process GO:0006644 61 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
single organism behavior GO:0044708 130 0.019
mesenchymal cell proliferation GO:0010463 4 0.019
single organism intracellular transport GO:1902582 166 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
purine nucleoside monophosphate catabolic process GO:0009128 55 0.019
positive regulation of immune system process GO:0002684 90 0.019
regulation of leukocyte migration GO:0002685 24 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
cytoplasmic transport GO:0016482 115 0.019
sensory perception of pain GO:0019233 73 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of hydrolase activity GO:0051336 143 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
nucleoside metabolic process GO:0009116 179 0.018
endocytosis GO:0006897 84 0.018
response to purine containing compound GO:0014074 126 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
metal ion homeostasis GO:0055065 186 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
vasculature development GO:0001944 70 0.018
ameboidal type cell migration GO:0001667 26 0.018
regulation of developmental growth GO:0048638 45 0.018
gliogenesis GO:0042063 93 0.018
tube development GO:0035295 89 0.018
Human Mouse
regulation of fat cell differentiation GO:0045598 3 0.018
ribonucleoside monophosphate metabolic process GO:0009161 88 0.018
organophosphate catabolic process GO:0046434 148 0.018
nitrogen compound transport GO:0071705 229 0.018
blood vessel morphogenesis GO:0048514 58 0.018
regulation of hormone secretion GO:0046883 106 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
response to hexose GO:0009746 144 0.017
Rat
negative regulation of developmental process GO:0051093 125 0.017
peptidyl amino acid modification GO:0018193 126 0.017
embryonic appendage morphogenesis GO:0035113 4 0.017
development of primary sexual characteristics GO:0045137 107 0.017
cellular protein localization GO:0034613 122 0.017
response to interleukin 1 GO:0070555 55 0.017
Rat
activation of protein kinase activity GO:0032147 47 0.017
response to external biotic stimulus GO:0043207 221 0.017
Rat
monosaccharide metabolic process GO:0005996 61 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
small molecule catabolic process GO:0044282 59 0.017
regulation of metanephros development GO:0072215 4 0.017
axis specification GO:0009798 4 0.017
glial cell differentiation GO:0010001 65 0.017
muscle structure development GO:0061061 87 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
oxidation reduction process GO:0055114 304 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
action potential GO:0001508 54 0.016
actin cytoskeleton organization GO:0030036 73 0.016
regulation of cell cycle GO:0051726 73 0.016
regulation of transmembrane transport GO:0034762 122 0.016
muscle tissue development GO:0060537 58 0.016
female gonad development GO:0008585 53 0.016
response to mechanical stimulus GO:0009612 134 0.016
cellular response to oxygen levels GO:0071453 60 0.016
skeletal muscle organ development GO:0060538 33 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of inflammatory response GO:0050727 48 0.016
neural crest cell migration GO:0001755 1 0.016
regulation of muscle contraction GO:0006937 53 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
ovulation cycle GO:0042698 67 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
response to acid chemical GO:0001101 222 0.016
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.015
single organismal cell cell adhesion GO:0016337 42 0.015
sequestering of metal ion GO:0051238 9 0.015
cyclic nucleotide biosynthetic process GO:0009190 63 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
positive regulation of response to wounding GO:1903036 34 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
carboxylic acid catabolic process GO:0046395 49 0.015
divalent metal ion transport GO:0070838 132 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.015
cell part morphogenesis GO:0032990 123 0.015
mesoderm formation GO:0001707 1 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
heart contraction GO:0060047 57 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
hormone secretion GO:0046879 115 0.015
regulation of cell projection organization GO:0031344 175 0.015
angiogenesis GO:0001525 53 0.015
neuron projection guidance GO:0097485 24 0.015
regulation of defense response GO:0031347 68 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
nucleoside monophosphate catabolic process GO:0009125 56 0.015
female pregnancy GO:0007565 122 0.015
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
nucleotide catabolic process GO:0009166 139 0.014
neural crest cell development GO:0014032 2 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
nucleoside catabolic process GO:0009164 126 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
macromolecule catabolic process GO:0009057 58 0.014
positive regulation of gene expression GO:0010628 244 0.014
peptide secretion GO:0002790 86 0.014
response to cold GO:0009409 29 0.014
sensory perception GO:0007600 101 0.014
regulation of response to external stimulus GO:0032101 106 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
intracellular transport GO:0046907 185 0.014
regulation of blood vessel endothelial cell migration GO:0043535 4 0.014
dendrite morphogenesis GO:0048813 43 0.014
cellular response to ketone GO:1901655 51 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014

Pcsk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
disease of metabolism DOID:0014667 0 0.016
organ system cancer DOID:0050686 0 0.015
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014