Rattus norvegicus

0 known processes

Lmod1

leiomodin 1 (smooth muscle)

Lmod1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to ketone GO:1901654 182 0.112
negative regulation of response to stimulus GO:0048585 155 0.095
organic acid metabolic process GO:0006082 292 0.095
macromolecular complex subunit organization GO:0043933 339 0.086
intracellular signal transduction GO:0035556 314 0.078
muscle system process GO:0003012 115 0.064
cellular response to hormone stimulus GO:0032870 247 0.064
response to corticosteroid GO:0031960 235 0.062
positive regulation of phosphorus metabolic process GO:0010562 262 0.061
regulation of cellular ketone metabolic process GO:0010565 27 0.060
response to acid chemical GO:0001101 222 0.059
cellular amino acid metabolic process GO:0006520 107 0.059
protein complex subunit organization GO:0071822 302 0.059
response to peptide hormone GO:0043434 278 0.058
response to extracellular stimulus GO:0009991 380 0.058
regulation of neurogenesis GO:0050767 247 0.058
cellular response to endogenous stimulus GO:0071495 377 0.057
neuron development GO:0048666 286 0.056
tissue development GO:0009888 252 0.054
cellular ketone metabolic process GO:0042180 51 0.052
single organism organelle organization GO:1902589 180 0.052
oxoacid metabolic process GO:0043436 290 0.049
cell projection organization GO:0030030 302 0.049
regulation of cellular amino acid metabolic process GO:0006521 2 0.048
carboxylic acid metabolic process GO:0019752 289 0.047
cell migration GO:0016477 197 0.046
protein phosphorylation GO:0006468 345 0.046
reproductive process GO:0022414 372 0.044
positive regulation of cellular component organization GO:0051130 200 0.044
regulation of neuron differentiation GO:0045664 208 0.044
multi organism reproductive process GO:0044703 262 0.044
positive regulation of nervous system development GO:0051962 178 0.042
positive regulation of biosynthetic process GO:0009891 319 0.042
single organism reproductive process GO:0044702 297 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.041
cell fate determination GO:0001709 2 0.041
response to estrogen GO:0043627 232 0.041
cellular component morphogenesis GO:0032989 155 0.041
neuron differentiation GO:0030182 368 0.041
cellular component biogenesis GO:0044085 368 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.040
regulation of nervous system development GO:0051960 264 0.040
positive regulation of neurogenesis GO:0050769 165 0.040
response to lipopolysaccharide GO:0032496 191 0.039
regulation of organelle organization GO:0033043 80 0.039
female pregnancy GO:0007565 122 0.039
mesoderm development GO:0007498 2 0.039
cellular component movement GO:0006928 248 0.038
cellular response to lipid GO:0071396 201 0.038
neuron projection development GO:0031175 273 0.036
peptidyl amino acid modification GO:0018193 126 0.036
sex differentiation GO:0007548 113 0.036
protein complex assembly GO:0006461 263 0.036
regulation of cellular component organization GO:0051128 368 0.036
regulation of cell proliferation GO:0042127 359 0.035
response to bacterium GO:0009617 200 0.035
response to peptide GO:1901652 292 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
cardiac muscle contraction GO:0060048 27 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
negative regulation of metabolic process GO:0009892 331 0.033
muscle contraction GO:0006936 88 0.033
regulation of molecular function GO:0065009 398 0.033
regulation of cell differentiation GO:0045595 320 0.032
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
multi multicellular organism process GO:0044706 138 0.032
cell motility GO:0048870 202 0.032
central nervous system development GO:0007417 311 0.031
response to inorganic substance GO:0010035 377 0.031
positive regulation of gene expression GO:0010628 244 0.031
positive regulation of developmental process GO:0051094 283 0.031
locomotion GO:0040011 237 0.031
organelle organization GO:0006996 266 0.031
regulation of signal transduction GO:0009966 318 0.031
response to nutrient levels GO:0031667 370 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
positive regulation of molecular function GO:0044093 230 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
aging GO:0007568 241 0.029
cellular component assembly GO:0022607 360 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
cellular catabolic process GO:0044248 295 0.028
cell morphogenesis GO:0000902 142 0.028
single organism biosynthetic process GO:0044711 342 0.027
regulation of catalytic activity GO:0050790 304 0.027
nucleic acid templated transcription GO:0097659 379 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
regulation of hormone levels GO:0010817 187 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
regulation of cell projection organization GO:0031344 175 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
regulation of g0 to g1 transition GO:0070316 3 0.026
anterior posterior pattern specification GO:0009952 1 0.026
macromolecular complex assembly GO:0065003 273 0.026
response to glucocorticoid GO:0051384 223 0.026
regulation of cell development GO:0060284 263 0.026
reproductive structure development GO:0048608 128 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
growth GO:0040007 165 0.025
intracellular transport GO:0046907 185 0.025
cellular amine metabolic process GO:0044106 38 0.025
hepaticobiliary system development GO:0061008 90 0.025
positive regulation of cell development GO:0010720 176 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of hydrolase activity GO:0051336 143 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
cell part morphogenesis GO:0032990 123 0.024
regulation of neuron projection development GO:0010975 161 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
blood circulation GO:0008015 183 0.024
multicellular organism reproduction GO:0032504 233 0.024
rna biosynthetic process GO:0032774 380 0.024
response to wounding GO:0009611 254 0.024
reproduction GO:0000003 245 0.024
regulation of transcription dna templated GO:0006355 374 0.024
actin filament based process GO:0030029 86 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.023
negative regulation of cellular component organization GO:0051129 83 0.023
catabolic process GO:0009056 351 0.023
positive regulation of signaling GO:0023056 270 0.023
cell type specific apoptotic process GO:0097285 134 0.023
cell adhesion GO:0007155 110 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
regulation of protein metabolic process GO:0051246 289 0.023
heart contraction GO:0060047 57 0.023
negative regulation of signaling GO:0023057 157 0.023
sensory organ development GO:0007423 74 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
development of primary sexual characteristics GO:0045137 107 0.022
negative regulation of cell communication GO:0010648 158 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
rna metabolic process GO:0016070 406 0.022
response to growth factor GO:0070848 189 0.022
response to cytokine GO:0034097 215 0.022
regulation of rna metabolic process GO:0051252 391 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
cytoskeleton organization GO:0007010 111 0.022
positive regulation of cell communication GO:0010647 271 0.022
response to metal ion GO:0010038 253 0.022
regulation of cellular component movement GO:0051270 150 0.022
apoptotic process GO:0006915 381 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
positive regulation of signal transduction GO:0009967 175 0.021
localization of cell GO:0051674 202 0.021
nucleotide metabolic process GO:0009117 279 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
organ morphogenesis GO:0009887 75 0.021
regulation of apoptotic process GO:0042981 335 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
response to ethanol GO:0045471 162 0.020
protein complex biogenesis GO:0070271 263 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
regulation of phosphorylation GO:0042325 248 0.020
neuron fate commitment GO:0048663 4 0.020
neuron projection morphogenesis GO:0048812 122 0.020
transcription dna templated GO:0006351 377 0.020
ras protein signal transduction GO:0007265 29 0.020
negative regulation of signal transduction GO:0009968 83 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.019
positive regulation of cellular component biogenesis GO:0044089 55 0.019
regulation of transferase activity GO:0051338 123 0.019
gastrulation GO:0007369 2 0.019
organophosphate metabolic process GO:0019637 370 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
dorsal ventral axon guidance GO:0033563 1 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
inflammatory response GO:0006954 150 0.019
negative regulation of gene expression GO:0010629 199 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
negative regulation of cell death GO:0060548 229 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
behavior GO:0007610 205 0.018
gliogenesis GO:0042063 93 0.018
lipid metabolic process GO:0006629 283 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
response to other organism GO:0051707 220 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
gonad development GO:0008406 104 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
heart morphogenesis GO:0003007 3 0.018
circulatory system development GO:0072359 134 0.018
heart process GO:0003015 57 0.018
response to retinoic acid GO:0032526 63 0.017
reproductive system development GO:0061458 128 0.017
response to radiation GO:0009314 137 0.017
positive regulation of saliva secretion GO:0046878 3 0.017
circulatory system process GO:0003013 183 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
mapk cascade GO:0000165 140 0.017
negative regulation of transport GO:0051051 136 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
tube development GO:0035295 89 0.017
regulation of cellular component biogenesis GO:0044087 86 0.016
liver development GO:0001889 90 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
multicellular organism growth GO:0035264 1 0.016
regeneration GO:0031099 163 0.016
mechanoreceptor differentiation GO:0042490 2 0.016
wound healing GO:0042060 122 0.016
regulation of blood vessel size GO:0050880 89 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
regulation of immune system process GO:0002682 123 0.016
transmission of nerve impulse GO:0019226 42 0.016
actin cytoskeleton organization GO:0030036 73 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
cell projection morphogenesis GO:0048858 123 0.016
regulation of fat cell differentiation GO:0045598 3 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
programmed cell death GO:0012501 392 0.015
hormone secretion GO:0046879 115 0.015
gland development GO:0048732 155 0.015
b cell differentiation GO:0030183 2 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
regulation of homotypic cell cell adhesion GO:0034110 4 0.015
cellular response to stress GO:0033554 269 0.015
head development GO:0060322 247 0.015
defense response GO:0006952 194 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
neurological system process GO:0050877 219 0.015
amine metabolic process GO:0009308 38 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
cellular response to alcohol GO:0097306 87 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
cellular response to ketone GO:1901655 51 0.015
actin filament depolymerization GO:0030042 3 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of cytoskeleton organization GO:0051495 26 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of protein modification process GO:0031399 194 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
homeostatic process GO:0042592 331 0.014
biological adhesion GO:0022610 110 0.014
embryonic appendage morphogenesis GO:0035113 4 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
epithelium development GO:0060429 96 0.014
response to interleukin 2 GO:0070669 1 0.014
metal ion homeostasis GO:0055065 186 0.014
camera type eye development GO:0043010 48 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of cell adhesion GO:0030155 52 0.014
regulation of bmp signaling pathway GO:0030510 2 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of multicellular organismal development GO:2000026 376 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cell growth GO:0016049 104 0.013
single organism intracellular transport GO:1902582 166 0.013
sensory perception of light stimulus GO:0050953 3 0.013
single organism catabolic process GO:0044712 283 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
cardiovascular system development GO:0072358 134 0.013
myelination GO:0042552 39 0.013
neural crest cell differentiation GO:0014033 2 0.013
positive regulation of ion transport GO:0043270 94 0.013
response to activity GO:0014823 73 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
regulation of kinase activity GO:0043549 117 0.013
response to fatty acid GO:0070542 65 0.013
protein oligomerization GO:0051259 191 0.013
negative regulation of atp catabolic process GO:1903290 2 0.013
choline transport GO:0015871 4 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
proteolysis GO:0006508 175 0.013
negative regulation of osteoblast differentiation GO:0045668 2 0.013
purine containing compound metabolic process GO:0072521 253 0.013
dendrite development GO:0016358 72 0.013
response to hexose GO:0009746 144 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
cytoplasmic transport GO:0016482 115 0.012
organophosphate catabolic process GO:0046434 148 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
lipid biosynthetic process GO:0008610 128 0.012
tube formation GO:0035148 3 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
cell activation GO:0001775 97 0.012
response to biotic stimulus GO:0009607 226 0.012
signal release GO:0023061 145 0.012
positive regulation of kinase activity GO:0033674 77 0.012
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.012
establishment of tissue polarity GO:0007164 2 0.012
peptide transport GO:0015833 97 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of blood circulation GO:1903524 65 0.012
regulation of heart contraction GO:0008016 48 0.012
regulation of muscle contraction GO:0006937 53 0.012
hormone metabolic process GO:0042445 69 0.012
cell cycle GO:0007049 101 0.012
response to carbohydrate GO:0009743 183 0.012
regulation of cellular localization GO:0060341 263 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
ovulation cycle GO:0042698 67 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
metal ion transport GO:0030001 289 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
response to hypoxia GO:0001666 231 0.012
muscle structure development GO:0061061 87 0.012
regulation of actin filament based process GO:0032970 42 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of mapk cascade GO:0043408 116 0.012
response to oxygen levels GO:0070482 265 0.012
cellular response to interleukin 2 GO:0071352 1 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
response to estradiol GO:0032355 164 0.012
epithelial cell differentiation GO:0030855 71 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
regulation of cell motility GO:2000145 131 0.011
positive regulation of organelle organization GO:0010638 48 0.011
response to mechanical stimulus GO:0009612 134 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
immune system process GO:0002376 204 0.011
developmental growth GO:0048589 100 0.011
neuronal action potential GO:0019228 35 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of tube size GO:0035150 89 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of ossification GO:0030278 32 0.011
cell cell signaling GO:0007267 335 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
eye morphogenesis GO:0048592 4 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to external biotic stimulus GO:0043207 221 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
anion transport GO:0006820 178 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of neuron death GO:1901214 115 0.011
response to nutrient GO:0007584 248 0.011
cellular lipid metabolic process GO:0044255 208 0.011
actin filament bundle organization GO:0061572 19 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
bmp signaling pathway GO:0030509 4 0.011
gamete generation GO:0007276 124 0.011
developmental process involved in reproduction GO:0003006 159 0.011
appendage morphogenesis GO:0035107 4 0.011
heart development GO:0007507 72 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
response to vitamin GO:0033273 131 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
organic substance catabolic process GO:1901575 316 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
regulation of locomotion GO:0040012 148 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.010
single organism cell adhesion GO:0098602 46 0.010
glomerular epithelial cell differentiation GO:0072311 2 0.010
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.010
platelet aggregation GO:0070527 4 0.010
cellular cation homeostasis GO:0030003 180 0.010
response to progesterone GO:0032570 48 0.010
chemical homeostasis GO:0048878 292 0.010
formation of primary germ layer GO:0001704 1 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
ion homeostasis GO:0050801 212 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
small molecule biosynthetic process GO:0044283 124 0.010
aromatic compound catabolic process GO:0019439 168 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
peptide hormone secretion GO:0030072 84 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010

Lmod1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.087
nervous system disease DOID:863 0 0.087
sensory system disease DOID:0050155 0 0.058
eye and adnexa disease DOID:1492 0 0.028
retinal disease DOID:5679 0 0.028
eye disease DOID:5614 0 0.028
musculoskeletal system disease DOID:17 0 0.017
retinal degeneration DOID:8466 0 0.016
cardiovascular system disease DOID:1287 0 0.014
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
central nervous system disease DOID:331 0 0.013
vascular disease DOID:178 0 0.012
disease of metabolism DOID:0014667 0 0.011
muscular dystrophy DOID:9884 0 0.010