Rattus norvegicus

0 known processes

Rnase2

ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)

(Aliases: Ear4,R5,R14,R15)

Rnase2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of catalytic activity GO:0050790 304 0.089
positive regulation of cell proliferation GO:0008284 249 0.086
response to inorganic substance GO:0010035 377 0.085
immune system process GO:0002376 204 0.085
Human
positive regulation of cell death GO:0010942 184 0.085
regulation of programmed cell death GO:0043067 341 0.080
regulation of transcription dna templated GO:0006355 374 0.069
programmed cell death GO:0012501 392 0.069
regulation of molecular function GO:0065009 398 0.069
response to metal ion GO:0010038 253 0.068
apoptotic process GO:0006915 381 0.068
transcription dna templated GO:0006351 377 0.065
response to peptide hormone GO:0043434 278 0.060
positive regulation of response to stimulus GO:0048584 285 0.060
regulation of rna metabolic process GO:0051252 391 0.058
positive regulation of apoptotic process GO:0043065 154 0.058
organic acid metabolic process GO:0006082 292 0.056
response to oxygen levels GO:0070482 265 0.055
regulation of phosphate metabolic process GO:0019220 349 0.052
regulation of rna biosynthetic process GO:2001141 381 0.052
response to hypoxia GO:0001666 231 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.046
protein phosphorylation GO:0006468 345 0.046
g protein coupled receptor signaling pathway GO:0007186 242 0.045
response to decreased oxygen levels GO:0036293 237 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
cellular response to oxygen containing compound GO:1901701 386 0.043
reproductive process GO:0022414 372 0.042
regulation of apoptotic process GO:0042981 335 0.042
wound healing GO:0042060 122 0.042
positive regulation of developmental process GO:0051094 283 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.041
homeostatic process GO:0042592 331 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
multi organism reproductive process GO:0044703 262 0.040
response to external biotic stimulus GO:0043207 221 0.040
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.040
regulation of protein metabolic process GO:0051246 289 0.039
nucleic acid templated transcription GO:0097659 379 0.039
negative regulation of metabolic process GO:0009892 331 0.039
response to reactive oxygen species GO:0000302 120 0.039
oxoacid metabolic process GO:0043436 290 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.039
intracellular transport GO:0046907 185 0.038
response to wounding GO:0009611 254 0.038
protein complex biogenesis GO:0070271 263 0.037
response to carbohydrate GO:0009743 183 0.037
macromolecule localization GO:0033036 252 0.036
response to lipopolysaccharide GO:0032496 191 0.036
regulation of cell proliferation GO:0042127 359 0.036
cellular response to lipid GO:0071396 201 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
response to bacterium GO:0009617 200 0.035
Human
regulation of protein phosphorylation GO:0001932 183 0.035
rna metabolic process GO:0016070 406 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
cellular ketone metabolic process GO:0042180 51 0.035
chemical homeostasis GO:0048878 292 0.035
regulation of phosphorylation GO:0042325 248 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
secretion by cell GO:0032940 248 0.034
carboxylic acid metabolic process GO:0019752 289 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
cellular response to organic cyclic compound GO:0071407 202 0.032
rna biosynthetic process GO:0032774 380 0.032
multicellular organism reproduction GO:0032504 233 0.032
response to biotic stimulus GO:0009607 226 0.031
Human
single organism biosynthetic process GO:0044711 342 0.031
positive regulation of programmed cell death GO:0043068 157 0.031
positive regulation of catalytic activity GO:0043085 184 0.031
positive regulation of locomotion GO:0040017 102 0.031
neuron projection development GO:0031175 273 0.030
regulation of anatomical structure size GO:0090066 135 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
response to mechanical stimulus GO:0009612 134 0.030
regulation of response to external stimulus GO:0032101 106 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
response to acid chemical GO:0001101 222 0.029
protein oligomerization GO:0051259 191 0.029
localization of cell GO:0051674 202 0.029
divalent inorganic cation transport GO:0072511 134 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
tissue development GO:0009888 252 0.028
intracellular signal transduction GO:0035556 314 0.028
negative regulation of gene expression GO:0010629 199 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
cell cell signaling GO:0007267 335 0.028
negative regulation of cell death GO:0060548 229 0.028
cardiovascular system development GO:0072358 134 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
protein complex assembly GO:0006461 263 0.028
regulation of secretion by cell GO:1903530 208 0.028
regulation of cell differentiation GO:0045595 320 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
regulation of signal transduction GO:0009966 318 0.027
protein homotrimerization GO:0070207 15 0.027
cation transport GO:0006812 382 0.027
response to oxidative stress GO:0006979 186 0.027
neuron differentiation GO:0030182 368 0.027
cellular response to peptide GO:1901653 133 0.027
response to peptide GO:1901652 292 0.027
reproduction GO:0000003 245 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
positive regulation of cell migration GO:0030335 96 0.027
growth GO:0040007 165 0.026
cellular homeostasis GO:0019725 252 0.026
regeneration GO:0031099 163 0.026
cellular chemical homeostasis GO:0055082 247 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
protein complex subunit organization GO:0071822 302 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
aging GO:0007568 241 0.025
regulation of protein modification process GO:0031399 194 0.025
secretion GO:0046903 307 0.025
positive regulation of cell communication GO:0010647 271 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
positive regulation of molecular function GO:0044093 230 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
regulation of smooth muscle cell proliferation GO:0048660 75 0.024
amine metabolic process GO:0009308 38 0.024
negative regulation of developmental process GO:0051093 125 0.024
positive regulation of gene expression GO:0010628 244 0.024
single organism intracellular transport GO:1902582 166 0.024
regulation of secretion GO:0051046 224 0.024
cellular metal ion homeostasis GO:0006875 172 0.024
metal ion transport GO:0030001 289 0.024
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of kinase activity GO:0043549 117 0.023
carbohydrate metabolic process GO:0005975 130 0.023
catabolic process GO:0009056 351 0.023
neurological system process GO:0050877 219 0.023
organophosphate metabolic process GO:0019637 370 0.023
cation homeostasis GO:0055080 195 0.023
positive regulation of protein modification process GO:0031401 142 0.023
single organism reproductive process GO:0044702 297 0.023
response to monosaccharide GO:0034284 159 0.023
nucleotide metabolic process GO:0009117 279 0.023
response to hyperoxia GO:0055093 45 0.023
cellular cation homeostasis GO:0030003 180 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
response to growth factor GO:0070848 189 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
ion transmembrane transport GO:0034220 365 0.022
cellular ion homeostasis GO:0006873 184 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
cellular amine metabolic process GO:0044106 38 0.022
locomotion GO:0040011 237 0.022
Human
transmembrane transport GO:0055085 412 0.022
cellular component assembly GO:0022607 360 0.022
response to nutrient levels GO:0031667 370 0.022
regulation of cellular component organization GO:0051128 368 0.022
positive regulation of signaling GO:0023056 270 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
regulation of locomotion GO:0040012 148 0.022
cell motility GO:0048870 202 0.022
response to nutrient GO:0007584 248 0.021
establishment of protein localization GO:0045184 141 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
regulation of cell motility GO:2000145 131 0.021
organic substance catabolic process GO:1901575 316 0.021
regulation of ion transport GO:0043269 245 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
muscle cell proliferation GO:0033002 84 0.021
protein localization GO:0008104 191 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
macromolecular complex assembly GO:0065003 273 0.020
proteolysis GO:0006508 175 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of hydrolase activity GO:0051336 143 0.020
regulation of cellular component movement GO:0051270 150 0.019
protein transport GO:0015031 132 0.019
immune response GO:0006955 104 0.019
Human
regulation of protein kinase activity GO:0045859 105 0.019
regulation of system process GO:0044057 208 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
biological adhesion GO:0022610 110 0.019
calcium ion transport GO:0006816 131 0.019
cell projection organization GO:0030030 302 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
cellular response to stress GO:0033554 269 0.019
cellular component biogenesis GO:0044085 368 0.018
smooth muscle cell proliferation GO:0048659 77 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
response to ethanol GO:0045471 162 0.018
response to insulin GO:0032868 133 0.018
metal ion homeostasis GO:0055065 186 0.018
sexual reproduction GO:0019953 148 0.018
response to extracellular stimulus GO:0009991 380 0.018
calcium ion homeostasis GO:0055074 162 0.018
gamete generation GO:0007276 124 0.018
circulatory system development GO:0072359 134 0.018
response to hexose GO:0009746 144 0.018
single organismal cell cell adhesion GO:0016337 42 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
neuron development GO:0048666 286 0.017
regulation of cell adhesion GO:0030155 52 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
single organism catabolic process GO:0044712 283 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
divalent metal ion transport GO:0070838 132 0.017
cellular component movement GO:0006928 248 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
response to ketone GO:1901654 182 0.017
positive regulation of response to external stimulus GO:0032103 51 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
lipid metabolic process GO:0006629 283 0.017
gliogenesis GO:0042063 93 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
positive regulation of nervous system development GO:0051962 178 0.017
positive regulation of cellular component movement GO:0051272 102 0.016
negative regulation of transport GO:0051051 136 0.016
regulation of cellular localization GO:0060341 263 0.016
regulation of transferase activity GO:0051338 123 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
cell growth GO:0016049 104 0.016
response to vitamin GO:0033273 131 0.016
ion homeostasis GO:0050801 212 0.016
learning or memory GO:0007611 90 0.016
cellular macromolecule localization GO:0070727 122 0.016
hormone secretion GO:0046879 115 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
cellular response to external stimulus GO:0071496 118 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
synaptic transmission GO:0007268 235 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
positive regulation of cell differentiation GO:0045597 217 0.015
cell adhesion GO:0007155 110 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
inflammatory response GO:0006954 150 0.015
regulation of response to stress GO:0080134 126 0.015
positive regulation of secretion GO:0051047 140 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
organ regeneration GO:0031100 101 0.015
central nervous system development GO:0007417 311 0.015
response to temperature stimulus GO:0009266 94 0.015
epithelium development GO:0060429 96 0.015
response to organophosphorus GO:0046683 102 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of cell communication GO:0010648 158 0.015
regulation of vasculature development GO:1901342 44 0.015
cytoplasmic transport GO:0016482 115 0.015
protein heterooligomerization GO:0051291 89 0.015
dna metabolic process GO:0006259 96 0.015
regulation of metal ion transport GO:0010959 118 0.015
response to estrogen GO:0043627 232 0.015
potassium ion transport GO:0006813 97 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of signal transduction GO:0009967 175 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of nervous system development GO:0051960 264 0.014
regulation of immune system process GO:0002682 123 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
response to heat GO:0009408 60 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
organelle organization GO:0006996 266 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
leukocyte cell cell adhesion GO:0007159 4 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
response to amino acid GO:0043200 75 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
regulation of cell development GO:0060284 263 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cellular lipid metabolic process GO:0044255 208 0.014
regulation of cell migration GO:0030334 128 0.014
regulation of tube size GO:0035150 89 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
regulation of growth GO:0040008 105 0.013
defense response GO:0006952 194 0.013
Human
positive regulation of neurogenesis GO:0050769 165 0.013
response to activity GO:0014823 73 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
response to increased oxygen levels GO:0036296 45 0.013
blood circulation GO:0008015 183 0.013
response to hydrogen peroxide GO:0042542 89 0.013
cellular catabolic process GO:0044248 295 0.013
positive regulation of cell motility GO:2000147 97 0.013
muscle system process GO:0003012 115 0.013
gland development GO:0048732 155 0.013
cell type specific apoptotic process GO:0097285 134 0.013
positive regulation of transferase activity GO:0051347 81 0.013
positive regulation of immune system process GO:0002684 90 0.013
blood vessel development GO:0001568 69 0.013
response to purine containing compound GO:0014074 126 0.013
muscle structure development GO:0061061 87 0.013
peptidyl amino acid modification GO:0018193 126 0.013
cellular response to alcohol GO:0097306 87 0.013
response to fatty acid GO:0070542 65 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
mapk cascade GO:0000165 140 0.012
regulation of blood circulation GO:1903522 110 0.012
response to glucose GO:0009749 136 0.012
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
cellular response to fluid shear stress GO:0071498 4 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
behavior GO:0007610 205 0.012
positive regulation of blood coagulation GO:0030194 4 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cell migration GO:0016477 197 0.012
regulation of angiogenesis GO:0045765 39 0.012
nucleoside metabolic process GO:0009116 179 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of response to wounding GO:1903034 69 0.012
vasculature development GO:0001944 70 0.012
regulation of homeostatic process GO:0032844 101 0.012
response to radiation GO:0009314 137 0.011
muscle contraction GO:0006936 88 0.011
positive regulation of kinase activity GO:0033674 77 0.011
glucose homeostasis GO:0042593 75 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of map kinase activity GO:0043405 53 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
male gamete generation GO:0048232 99 0.011
maintenance of location GO:0051235 17 0.011
signal release GO:0023061 145 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
head development GO:0060322 247 0.011
positive regulation of cell development GO:0010720 176 0.011
vasoconstriction GO:0042310 54 0.011
positive regulation of transport GO:0051050 245 0.011
small molecule biosynthetic process GO:0044283 124 0.011
sequestering of calcium ion GO:0051208 8 0.011
sensory perception GO:0007600 101 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
brain development GO:0007420 247 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
female pregnancy GO:0007565 122 0.011
regulation of neurogenesis GO:0050767 247 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of blood circulation GO:1903524 65 0.011
axis specification GO:0009798 4 0.011
tube development GO:0035295 89 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
Human
catecholamine secretion GO:0050432 33 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
angiogenesis GO:0001525 53 0.011
purine containing compound catabolic process GO:0072523 138 0.011
negative regulation of catalytic activity GO:0043086 103 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.010
regulation of neuron differentiation GO:0045664 208 0.010
sensory perception of bitter taste GO:0050913 4 0.010
regulation of calcium ion transport GO:0051924 77 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
fertilization GO:0009566 3 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
nitrogen compound transport GO:0071705 229 0.010
heterocycle catabolic process GO:0046700 167 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
organophosphate catabolic process GO:0046434 148 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
regulation of peptide transport GO:0090087 87 0.010
cellular component morphogenesis GO:0032989 155 0.010

Rnase2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.014