Rattus norvegicus

0 known processes

Prl6a1

prolactin family 6, subfamily a, member 1

(Aliases: Plpb,Prlpb)

Prl6a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 219 0.481
positive regulation of cell proliferation GO:0008284 249 0.403
Rat
intracellular signal transduction GO:0035556 314 0.280
response to peptide hormone GO:0043434 278 0.263
Rat
regulation of signal transduction GO:0009966 318 0.227
Rat
localization of cell GO:0051674 202 0.181
response to carbohydrate GO:0009743 183 0.179
blood circulation GO:0008015 183 0.170
response to estradiol GO:0032355 164 0.164
Rat
response to extracellular stimulus GO:0009991 380 0.154
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.152
positive regulation of signaling GO:0023056 270 0.142
Rat
regulation of system process GO:0044057 208 0.139
response to glucose GO:0009749 136 0.139
regulation of neuron death GO:1901214 115 0.132
Rat
protein phosphorylation GO:0006468 345 0.132
Rat
regulation of immune system process GO:0002682 123 0.127
circulatory system process GO:0003013 183 0.125
regulation of phosphorus metabolic process GO:0051174 349 0.124
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.120
Rat
response to monosaccharide GO:0034284 159 0.118
positive regulation of phosphorus metabolic process GO:0010562 262 0.111
Rat
response to hexose GO:0009746 144 0.109
positive regulation of signal transduction GO:0009967 175 0.105
Rat
cation transmembrane transport GO:0098655 263 0.099
positive regulation of biosynthetic process GO:0009891 319 0.099
Rat
regulation of blood circulation GO:1903522 110 0.098
cellular response to hormone stimulus GO:0032870 247 0.095
Rat
neuron death GO:0070997 127 0.095
Rat
positive regulation of molecular function GO:0044093 230 0.094
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.093
Rat
regulation of protein modification process GO:0031399 194 0.087
Rat
calcium ion import GO:0070509 22 0.080
anatomical structure morphogenesis GO:0009653 298 0.079
cellular response to organic cyclic compound GO:0071407 202 0.078
organophosphate metabolic process GO:0019637 370 0.077
negative regulation of neuron death GO:1901215 69 0.077
Rat
response to molecule of bacterial origin GO:0002237 194 0.076
Rat
cellular response to oxygen containing compound GO:1901701 386 0.075
single organism reproductive process GO:0044702 297 0.074
Rat
response to estrogen GO:0043627 232 0.074
Rat
response to peptide GO:1901652 292 0.074
Rat
regulation of cell proliferation GO:0042127 359 0.074
Rat
chemical homeostasis GO:0048878 292 0.072
positive regulation of nucleic acid templated transcription GO:1903508 197 0.071
respiratory system development GO:0060541 45 0.070
Rat
positive regulation of response to stimulus GO:0048584 285 0.069
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.068
reproductive process GO:0022414 372 0.068
Rat
organ morphogenesis GO:0009887 75 0.067
negative regulation of multicellular organismal process GO:0051241 203 0.067
cgmp biosynthetic process GO:0006182 15 0.066
cellular chemical homeostasis GO:0055082 247 0.066
regulation of cell motility GO:2000145 131 0.066
positive regulation of gene expression GO:0010628 244 0.065
positive regulation of protein phosphorylation GO:0001934 135 0.064
Rat
positive regulation of protein modification process GO:0031401 142 0.064
Rat
cognition GO:0050890 92 0.063
metal ion homeostasis GO:0055065 186 0.063
regulation of protein metabolic process GO:0051246 289 0.063
Rat
positive regulation of catalytic activity GO:0043085 184 0.062
Rat
regulation of rna biosynthetic process GO:2001141 381 0.062
cellular response to endogenous stimulus GO:0071495 377 0.062
Rat
regulation of cellular component movement GO:0051270 150 0.060
response to wounding GO:0009611 254 0.060
cellular response to organonitrogen compound GO:0071417 197 0.060
vascular process in circulatory system GO:0003018 96 0.060
regulation of transcription dna templated GO:0006355 374 0.059
vasodilation GO:0042311 44 0.059
cell motility GO:0048870 202 0.058
regulation of neuron apoptotic process GO:0043523 83 0.058
protein homooligomerization GO:0051260 91 0.057
single organism behavior GO:0044708 130 0.057
sensory perception GO:0007600 101 0.057
locomotory exploration behavior GO:0035641 1 0.057
sensory perception of pain GO:0019233 73 0.056
response to cytokine GO:0034097 215 0.055
Rat
regulation of phosphate metabolic process GO:0019220 349 0.055
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.055
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.054
rna metabolic process GO:0016070 406 0.054
sequestering of metal ion GO:0051238 9 0.053
positive regulation of programmed cell death GO:0043068 157 0.052
regulation of protein phosphorylation GO:0001932 183 0.050
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.050
response to acid chemical GO:0001101 222 0.050
amine metabolic process GO:0009308 38 0.049
rna biosynthetic process GO:0032774 380 0.049
positive regulation of jak stat cascade GO:0046427 19 0.048
Rat
protein localization GO:0008104 191 0.048
positive regulation of phosphorylation GO:0042327 177 0.048
Rat
defense response GO:0006952 194 0.048
positive regulation of cell death GO:0010942 184 0.047
response to nutrient levels GO:0031667 370 0.047
Rat
regulation of smooth muscle cell proliferation GO:0048660 75 0.046
cell activation GO:0001775 97 0.046
ion transmembrane transport GO:0034220 365 0.046
cellular response to nitrogen compound GO:1901699 210 0.046
response to corticosteroid GO:0031960 235 0.046
inflammatory response GO:0006954 150 0.045
regulation of muscle contraction GO:0006937 53 0.045
cellular component movement GO:0006928 248 0.044
cell migration GO:0016477 197 0.043
synaptic transmission GO:0007268 235 0.042
response to interleukin 1 GO:0070555 55 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
cellular component biogenesis GO:0044085 368 0.042
regulation of phosphorylation GO:0042325 248 0.042
Rat
multicellular organismal reproductive process GO:0048609 233 0.042
Rat
regulation of kinase activity GO:0043549 117 0.042
Rat
behavior GO:0007610 205 0.041
regulation of intracellular signal transduction GO:1902531 218 0.041
Rat
homeostatic process GO:0042592 331 0.041
protein complex assembly GO:0006461 263 0.040
aging GO:0007568 241 0.040
regulation of programmed cell death GO:0043067 341 0.040
oxoacid metabolic process GO:0043436 290 0.040
mapk cascade GO:0000165 140 0.039
regulation of secretion GO:0051046 224 0.039
smooth muscle cell proliferation GO:0048659 77 0.039
response to metal ion GO:0010038 253 0.038
immune system process GO:0002376 204 0.038
response to other organism GO:0051707 220 0.038
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.038
positive regulation of transferase activity GO:0051347 81 0.037
Rat
cellular component assembly GO:0022607 360 0.037
heart process GO:0003015 57 0.037
response to glucocorticoid GO:0051384 223 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
regulation of rna metabolic process GO:0051252 391 0.037
macromolecular complex assembly GO:0065003 273 0.036
heart contraction GO:0060047 57 0.035
response to fatty acid GO:0070542 65 0.035
regulation of molecular function GO:0065009 398 0.034
Rat
regulation of cell development GO:0060284 263 0.034
Rat
cellular amine metabolic process GO:0044106 38 0.034
regulation of cellular component organization GO:0051128 368 0.033
protein oligomerization GO:0051259 191 0.033
cellular cation homeostasis GO:0030003 180 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
Rat
response to nutrient GO:0007584 248 0.032
Rat
negative regulation of luteinizing hormone secretion GO:0033685 4 0.032
apoptotic process GO:0006915 381 0.032
positive regulation of hydrolase activity GO:0051345 86 0.032
ion homeostasis GO:0050801 212 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
cytoplasmic transport GO:0016482 115 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.030
Rat
macromolecular complex subunit organization GO:0043933 339 0.030
cell projection organization GO:0030030 302 0.029
regulation of cell migration GO:0030334 128 0.029
multi multicellular organism process GO:0044706 138 0.029
Rat
positive regulation of transcription dna templated GO:0045893 197 0.029
positive regulation of cell communication GO:0010647 271 0.028
Rat
cellular amino acid metabolic process GO:0006520 107 0.028
jak stat cascade GO:0007259 26 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
response to insulin GO:0032868 133 0.028
response to bacterium GO:0009617 200 0.028
Rat
positive regulation of immune system process GO:0002684 90 0.028
regulation of epithelial cell proliferation GO:0050678 49 0.028
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
Rat
learning or memory GO:0007611 90 0.027
heart morphogenesis GO:0003007 3 0.027
rhythmic process GO:0048511 156 0.027
Rat
negative regulation of metabolic process GO:0009892 331 0.027
cellular response to stress GO:0033554 269 0.027
nucleotide metabolic process GO:0009117 279 0.027
response to light stimulus GO:0009416 52 0.027
Rat
response to ethanol GO:0045471 162 0.026
Rat
regulation of response to stress GO:0080134 126 0.026
response to electrical stimulus GO:0051602 56 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
carbohydrate metabolic process GO:0005975 130 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
cardiac muscle contraction GO:0060048 27 0.025
divalent metal ion transport GO:0070838 132 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
Rat
multi organism reproductive process GO:0044703 262 0.025
Rat
positive regulation of blood circulation GO:1903524 65 0.025
reproductive structure development GO:0048608 128 0.025
alpha amino acid metabolic process GO:1901605 71 0.025
neuron differentiation GO:0030182 368 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
cellular response to lipid GO:0071396 201 0.024
peptidyl amino acid modification GO:0018193 126 0.024
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to ketone GO:1901654 182 0.024
regulation of catalytic activity GO:0050790 304 0.024
Rat
cation transport GO:0006812 382 0.023
female pregnancy GO:0007565 122 0.023
Rat
regulation of transferase activity GO:0051338 123 0.023
Rat
response to oxidative stress GO:0006979 186 0.023
muscle system process GO:0003012 115 0.023
cellular response to glucose stimulus GO:0071333 65 0.023
cellular response to hexose stimulus GO:0071331 65 0.023
peptidyl tyrosine modification GO:0018212 72 0.023
Rat
glucose homeostasis GO:0042593 75 0.023
transmembrane transport GO:0055085 412 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
locomotion GO:0040011 237 0.022
gland development GO:0048732 155 0.022
regulation of cytokine production GO:0001817 56 0.022
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.022
ovulation cycle GO:0042698 67 0.022
Rat
single organism cellular localization GO:1902580 102 0.022
adult locomotory behavior GO:0008344 4 0.022
cellular response to acid chemical GO:0071229 75 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
neuron apoptotic process GO:0051402 88 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
axis specification GO:0009798 4 0.021
regulation of hydrolase activity GO:0051336 143 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
negative regulation of cell growth GO:0030308 33 0.021
regulation of mapk cascade GO:0043408 116 0.021
regulation of homeostatic process GO:0032844 101 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of cell differentiation GO:0045595 320 0.020
Rat
positive regulation of cell development GO:0010720 176 0.020
Rat
intracellular transport GO:0046907 185 0.020
positive regulation of mast cell activation GO:0033005 4 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
neuron projection development GO:0031175 273 0.019
negative regulation of growth GO:0045926 37 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
regulation of defecation GO:2000292 1 0.019
regulation of blood vessel size GO:0050880 89 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
cellular response to external stimulus GO:0071496 118 0.018
cell cell signaling GO:0007267 335 0.018
reproduction GO:0000003 245 0.018
Rat
signal release GO:0023061 145 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
purine containing compound metabolic process GO:0072521 253 0.018
positive regulation of serotonin secretion GO:0014064 1 0.018
carbohydrate homeostasis GO:0033500 75 0.018
response to decreased oxygen levels GO:0036293 237 0.018
epithelial cell differentiation GO:0030855 71 0.018
peptidyl tyrosine phosphorylation GO:0018108 72 0.018
Rat
axon ensheathment GO:0008366 40 0.018
regulation of blood pressure GO:0008217 83 0.018
regulation of heart contraction GO:0008016 48 0.018
tissue development GO:0009888 252 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.017
cellular homeostasis GO:0019725 252 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
amide transport GO:0042886 105 0.017
programmed cell death GO:0012501 392 0.017
peptide hormone secretion GO:0030072 84 0.017
regulation of cellular localization GO:0060341 263 0.017
single organism cell adhesion GO:0098602 46 0.017
regulation of myeloid cell differentiation GO:0045637 12 0.017
cell morphogenesis GO:0000902 142 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
positive regulation of cell migration GO:0030335 96 0.016
male mating behavior GO:0060179 3 0.016
regulation of excretion GO:0044062 21 0.016
transmission of nerve impulse GO:0019226 42 0.016
negative regulation of defecation GO:2000293 1 0.016
cytokine production GO:0001816 61 0.016
secretion by cell GO:0032940 248 0.016
positive regulation of cell motility GO:2000147 97 0.016
regulation of neurological system process GO:0031644 43 0.016
multicellular organism growth GO:0035264 1 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of calcium ion import GO:0090281 2 0.016
regulation of hormone levels GO:0010817 187 0.016
Rat
regulation of cell activation GO:0050865 50 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.015
Rat
cell type specific apoptotic process GO:0097285 134 0.015
cellular catabolic process GO:0044248 295 0.015
renal system process GO:0003014 40 0.015
sequestering of calcium ion GO:0051208 8 0.015
single organismal cell cell adhesion GO:0016337 42 0.015
excretion GO:0007588 24 0.015
memory GO:0007613 54 0.015
regulation of norepinephrine secretion GO:0014061 15 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
sexual reproduction GO:0019953 148 0.015
positive regulation of kinase activity GO:0033674 77 0.015
Rat
cellular response to mechanical stimulus GO:0071260 48 0.015
regulation of apoptotic process GO:0042981 335 0.015
cellular response to monosaccharide stimulus GO:0071326 67 0.015
carboxylic acid metabolic process GO:0019752 289 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
negative regulation of gene expression GO:0010629 199 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
transcription dna templated GO:0006351 377 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
cellular response to oxidative stress GO:0034599 76 0.014
response to mechanical stimulus GO:0009612 134 0.014
muscle cell proliferation GO:0033002 84 0.014
regulation of ion homeostasis GO:2000021 63 0.014
positive regulation of cytokine production GO:0001819 42 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
carboxylic acid transport GO:0046942 115 0.014
regulation of metal ion transport GO:0010959 118 0.014
cellular component morphogenesis GO:0032989 155 0.014
cellular response to carbohydrate stimulus GO:0071322 72 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
Rat
regulation of cell growth GO:0001558 85 0.014
negative regulation of cell death GO:0060548 229 0.014
Rat
cellular glucose homeostasis GO:0001678 66 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
response to temperature stimulus GO:0009266 94 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
regeneration GO:0031099 163 0.014
epithelium development GO:0060429 96 0.014
neuron development GO:0048666 286 0.014
single organism biosynthetic process GO:0044711 342 0.014
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
nucleic acid templated transcription GO:0097659 379 0.013
multicellular organism reproduction GO:0032504 233 0.013
Rat
response to amino acid GO:0043200 75 0.013
cellular protein localization GO:0034613 122 0.013
multicellular organismal response to stress GO:0033555 25 0.013
Rat
cellular response to insulin stimulus GO:0032869 81 0.013
regulation of membrane potential GO:0042391 110 0.013
defecation GO:0030421 1 0.013
positive regulation of leukocyte degranulation GO:0043302 4 0.013
ensheathment of neurons GO:0007272 40 0.013
neural crest cell migration GO:0001755 1 0.012
regulation of muscle system process GO:0090257 79 0.012
response to external biotic stimulus GO:0043207 221 0.012
Rat
cellular ketone metabolic process GO:0042180 51 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
liver development GO:0001889 90 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
protein complex subunit organization GO:0071822 302 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
regulation of secretion by cell GO:1903530 208 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
response to tumor necrosis factor GO:0034612 56 0.012
response to heat GO:0009408 60 0.012
regulation of anatomical structure size GO:0090066 135 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
neuronal action potential GO:0019228 35 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
male gamete generation GO:0048232 99 0.012
actin mediated cell contraction GO:0070252 12 0.012
cardiac conduction GO:0061337 2 0.012
olfactory learning GO:0008355 1 0.012
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.012
gamete generation GO:0007276 124 0.012
regulation of response to external stimulus GO:0032101 106 0.012
negative regulation of myeloid cell differentiation GO:0045638 3 0.012
growth GO:0040007 165 0.012
Rat
developmental growth GO:0048589 100 0.011
ameboidal type cell migration GO:0001667 26 0.011
protein homotrimerization GO:0070207 15 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
proteolysis GO:0006508 175 0.011
small molecule biosynthetic process GO:0044283 124 0.011
negative regulation of cell development GO:0010721 82 0.011
regulation of cell projection organization GO:0031344 175 0.011
positive regulation of myeloid leukocyte mediated immunity GO:0002888 4 0.011
regulation of potassium ion transport GO:0043266 29 0.011
monovalent inorganic cation homeostasis GO:0055067 36 0.011
regulation of neurogenesis GO:0050767 247 0.011
Rat
stress activated mapk cascade GO:0051403 35 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.011
cgmp metabolic process GO:0046068 22 0.011
regulation of intracellular transport GO:0032386 65 0.011
activation of protein kinase activity GO:0032147 47 0.011
Rat
response to radiation GO:0009314 137 0.011
Rat
multicellular organismal signaling GO:0035637 44 0.011
regulation of necroptotic process GO:0060544 2 0.011
leukocyte activation GO:0045321 76 0.011
gastric inhibitory peptide signaling pathway GO:0038192 1 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
macromolecule localization GO:0033036 252 0.011
central nervous system development GO:0007417 311 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
regulation of peptide secretion GO:0002791 82 0.011
regulation of transmembrane transport GO:0034762 122 0.011
organic acid metabolic process GO:0006082 292 0.011
cellular glucan metabolic process GO:0006073 23 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of synaptic plasticity GO:0048167 70 0.010
response to axon injury GO:0048678 59 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
regulation of growth GO:0040008 105 0.010
Rat
sex differentiation GO:0007548 113 0.010
regulation of tube size GO:0035150 89 0.010
regulation of nervous system development GO:0051960 264 0.010
Rat
calcium ion homeostasis GO:0055074 162 0.010
response to testosterone GO:0033574 55 0.010
response to osmotic stress GO:0006970 42 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
learning GO:0007612 33 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
ossification GO:0001503 70 0.010
Rat
activation of janus kinase activity GO:0042976 5 0.010
Rat
cellular response to peptide GO:1901653 133 0.010
organ regeneration GO:0031100 101 0.010
negative regulation of dopamine secretion GO:0033602 4 0.010
organic acid transport GO:0015849 116 0.010
neural precursor cell proliferation GO:0061351 23 0.010
Rat
protein tetramerization GO:0051262 38 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
Rat

Prl6a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.032
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.015
bone disease DOID:0080001 0 0.014
cardiovascular system disease DOID:1287 0 0.011