Rattus norvegicus

0 known processes

Hsd17b8

hydroxysteroid (17-beta) dehydrogenase 8

(Aliases: Ke6,Fabgl,MGC109594,RING2)

Hsd17b8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism catabolic process GO:0044712 283 0.102
macromolecular complex assembly GO:0065003 273 0.083
purine ribonucleoside catabolic process GO:0046130 124 0.066
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.063
purine nucleoside metabolic process GO:0042278 169 0.061
cellular catabolic process GO:0044248 295 0.056
organophosphate catabolic process GO:0046434 148 0.056
ribonucleoside triphosphate catabolic process GO:0009203 122 0.054
cellular component biogenesis GO:0044085 368 0.054
protein localization GO:0008104 191 0.052
macromolecule localization GO:0033036 252 0.052
purine nucleotide catabolic process GO:0006195 136 0.051
cellular component assembly GO:0022607 360 0.050
aromatic compound catabolic process GO:0019439 168 0.049
purine containing compound catabolic process GO:0072523 138 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
macromolecular complex subunit organization GO:0043933 339 0.046
protein complex biogenesis GO:0070271 263 0.046
rna metabolic process GO:0016070 406 0.046
regulation of phosphate metabolic process GO:0019220 349 0.045
heterocycle catabolic process GO:0046700 167 0.044
organelle organization GO:0006996 266 0.043
organic cyclic compound catabolic process GO:1901361 175 0.042
protein phosphorylation GO:0006468 345 0.042
purine containing compound metabolic process GO:0072521 253 0.041
protein complex assembly GO:0006461 263 0.040
nucleoside phosphate metabolic process GO:0006753 283 0.040
purine ribonucleotide catabolic process GO:0009154 136 0.039
purine nucleoside triphosphate metabolic process GO:0009144 141 0.039
nucleobase containing compound catabolic process GO:0034655 152 0.038
glycosyl compound catabolic process GO:1901658 126 0.038
neuron differentiation GO:0030182 368 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
nucleoside metabolic process GO:0009116 179 0.037
organonitrogen compound catabolic process GO:1901565 179 0.036
negative regulation of metabolic process GO:0009892 331 0.035
carbohydrate derivative catabolic process GO:1901136 147 0.035
nucleoside phosphate catabolic process GO:1901292 140 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
protein complex subunit organization GO:0071822 302 0.035
purine nucleoside catabolic process GO:0006152 124 0.034
regulation of cellular component organization GO:0051128 368 0.034
purine ribonucleoside metabolic process GO:0046128 168 0.033
nucleoside catabolic process GO:0009164 126 0.033
ribonucleoside triphosphate metabolic process GO:0009199 141 0.032
purine nucleoside triphosphate catabolic process GO:0009146 122 0.032
organic substance catabolic process GO:1901575 316 0.032
regulation of catalytic activity GO:0050790 304 0.032
transcription dna templated GO:0006351 377 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
regulation of phosphorylation GO:0042325 248 0.031
ribonucleoside catabolic process GO:0042454 126 0.031
purine nucleotide metabolic process GO:0006163 229 0.030
regulation of protein metabolic process GO:0051246 289 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
regulation of signal transduction GO:0009966 318 0.030
catabolic process GO:0009056 351 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
regulation of rna biosynthetic process GO:2001141 381 0.029
organophosphate metabolic process GO:0019637 370 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
ribonucleotide catabolic process GO:0009261 136 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.028
cellular nitrogen compound catabolic process GO:0044270 163 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
cellular macromolecule localization GO:0070727 122 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
nucleotide catabolic process GO:0009166 139 0.026
intracellular signal transduction GO:0035556 314 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
regulation of molecular function GO:0065009 398 0.026
regulation of programmed cell death GO:0043067 341 0.026
programmed cell death GO:0012501 392 0.026
rna biosynthetic process GO:0032774 380 0.025
anterior posterior pattern specification GO:0009952 1 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
neuron projection development GO:0031175 273 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
guanosine containing compound catabolic process GO:1901069 71 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
cellular amine metabolic process GO:0044106 38 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
oxoacid metabolic process GO:0043436 290 0.023
Yeast
positive regulation of gene expression GO:0010628 244 0.023
gtp catabolic process GO:0006184 71 0.023
regulation of intracellular signal transduction GO:1902531 218 0.022
neuron development GO:0048666 286 0.022
cation transport GO:0006812 382 0.022
nucleotide metabolic process GO:0009117 279 0.022
cell projection organization GO:0030030 302 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
protein oligomerization GO:0051259 191 0.021
amine metabolic process GO:0009308 38 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
protein refolding GO:0042026 3 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
cellular ketone metabolic process GO:0042180 51 0.021
cellular component movement GO:0006928 248 0.021
single organism biosynthetic process GO:0044711 342 0.021
Human
metal ion transport GO:0030001 289 0.020
regulation of hydrolase activity GO:0051336 143 0.020
actin filament based process GO:0030029 86 0.020
positive regulation of signaling GO:0023056 270 0.020
head development GO:0060322 247 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of protein modification process GO:0031399 194 0.020
cell motility GO:0048870 202 0.020
organic acid biosynthetic process GO:0016053 83 0.019
regulation of system process GO:0044057 208 0.019
response to inorganic substance GO:0010035 377 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
cellular protein localization GO:0034613 122 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
Yeast
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
single organism reproductive process GO:0044702 297 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
ion homeostasis GO:0050801 212 0.018
embryonic pattern specification GO:0009880 1 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
nucleic acid templated transcription GO:0097659 379 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
gastrulation GO:0007369 2 0.018
intracellular transport GO:0046907 185 0.017
positive regulation of molecular function GO:0044093 230 0.017
homeostatic process GO:0042592 331 0.017
cellular ion homeostasis GO:0006873 184 0.017
reproductive system development GO:0061458 128 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
regulation of cell differentiation GO:0045595 320 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.016
response to extracellular stimulus GO:0009991 380 0.016
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
reproductive process GO:0022414 372 0.016
brain development GO:0007420 247 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
vesicle mediated transport GO:0016192 181 0.016
positive regulation of cell communication GO:0010647 271 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
cation homeostasis GO:0055080 195 0.016
cytoskeleton organization GO:0007010 111 0.015
regulation of catabolic process GO:0009894 113 0.015
cellular response to stress GO:0033554 269 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
cellular chemical homeostasis GO:0055082 247 0.015
response to oxidative stress GO:0006979 186 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
cellular homeostasis GO:0019725 252 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of gene expression GO:0010629 199 0.015
chemical homeostasis GO:0048878 292 0.015
cellular cation homeostasis GO:0030003 180 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
protein heterooligomerization GO:0051291 89 0.015
protein localization to organelle GO:0033365 57 0.015
response to glucocorticoid GO:0051384 223 0.015
calcium ion homeostasis GO:0055074 162 0.014
reproduction GO:0000003 245 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of transcription dna templated GO:0006355 374 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
apoptotic process GO:0006915 381 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
cellular component morphogenesis GO:0032989 155 0.014
gtp metabolic process GO:0046039 72 0.014
cell migration GO:0016477 197 0.014
cell part morphogenesis GO:0032990 123 0.014
metal ion homeostasis GO:0055065 186 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
regulation of nervous system development GO:0051960 264 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
intracellular protein transport GO:0006886 79 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cytoplasmic transport GO:0016482 115 0.014
axis specification GO:0009798 4 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to metal ion GO:0010038 253 0.013
positive regulation of signal transduction GO:0009967 175 0.013
heart morphogenesis GO:0003007 3 0.013
locomotion GO:0040011 237 0.013
regulation of hormone levels GO:0010817 187 0.013
Human Mouse
regulation of secretion by cell GO:1903530 208 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of cell development GO:0060284 263 0.013
negative regulation of molecular function GO:0044092 133 0.013
embryonic axis specification GO:0000578 1 0.013
ras protein signal transduction GO:0007265 29 0.012
aging GO:0007568 241 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
muscle system process GO:0003012 115 0.012
blood circulation GO:0008015 183 0.012
cell projection morphogenesis GO:0048858 123 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
amide transport GO:0042886 105 0.012
negative regulation of signaling GO:0023057 157 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
negative regulation of protein modification process GO:0031400 52 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
single organism organelle organization GO:1902589 180 0.012
localization of cell GO:0051674 202 0.012
single organism intracellular transport GO:1902582 166 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of developmental process GO:0051094 283 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
organic acid metabolic process GO:0006082 292 0.011
Yeast
negative regulation of cell death GO:0060548 229 0.011
developmental process involved in reproduction GO:0003006 159 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
peptide transport GO:0015833 97 0.011
circulatory system process GO:0003013 183 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
establishment of protein localization GO:0045184 141 0.011
ion transmembrane transport GO:0034220 365 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of blood circulation GO:1903522 110 0.011
regulation of immune system process GO:0002682 123 0.011
peptidyl amino acid modification GO:0018193 126 0.011
lipid storage GO:0019915 1 0.011
secretion by cell GO:0032940 248 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
cell growth GO:0016049 104 0.011
gonad development GO:0008406 104 0.011
oxidation reduction process GO:0055114 304 0.011
Human Yeast Mouse
regulation of apoptotic process GO:0042981 335 0.010
centrosome organization GO:0051297 1 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
regulation of multicellular organismal development GO:2000026 376 0.010
regulation of neurogenesis GO:0050767 247 0.010
regulation of neuron projection development GO:0010975 161 0.010
microtubule organizing center organization GO:0031023 1 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
response to decreased oxygen levels GO:0036293 237 0.010
neuron projection morphogenesis GO:0048812 122 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
response to corticosteroid GO:0031960 235 0.010
defense response to gram negative bacterium GO:0050829 3 0.010

Hsd17b8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.014