Rattus norvegicus

19 known processes

Gpnmb

glycoprotein (transmembrane) nmb

Gpnmb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.573
regulation of immune system process GO:0002682 123 0.213
inflammatory response GO:0006954 150 0.146
granulocyte chemotaxis GO:0071621 15 0.139
homeostatic process GO:0042592 331 0.124
single organism reproductive process GO:0044702 297 0.123
response to molecule of bacterial origin GO:0002237 194 0.112
positive regulation of response to stimulus GO:0048584 285 0.112
positive regulation of immune system process GO:0002684 90 0.111
multicellular organism reproduction GO:0032504 233 0.103
immune response GO:0006955 104 0.101
biological adhesion GO:0022610 110 0.095
negative regulation of multicellular organismal process GO:0051241 203 0.095
programmed cell death GO:0012501 392 0.093
response to extracellular stimulus GO:0009991 380 0.090
regulation of programmed cell death GO:0043067 341 0.089
myeloid cell apoptotic process GO:0033028 6 0.087
neutrophil apoptotic process GO:0001781 4 0.082
regulation of apoptotic process GO:0042981 335 0.079
neuron differentiation GO:0030182 368 0.078
defense response GO:0006952 194 0.077
regulation of smooth muscle cell proliferation GO:0048660 75 0.071
regulation of cell projection organization GO:0031344 175 0.070
multi multicellular organism process GO:0044706 138 0.070
regulation of neutrophil apoptotic process GO:0033029 4 0.069
regeneration GO:0031099 163 0.069
response to nutrient levels GO:0031667 370 0.064
cell motility GO:0048870 202 0.061
negative regulation of cell death GO:0060548 229 0.058
neuron projection development GO:0031175 273 0.058
eosinophil migration GO:0072677 3 0.057
regulation of signal transduction GO:0009966 318 0.056
immune response regulating signaling pathway GO:0002764 19 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.055
multicellular organismal reproductive process GO:0048609 233 0.051
cell activation GO:0001775 97 0.049
locomotion GO:0040011 237 0.049
aging GO:0007568 241 0.049
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
cell adhesion GO:0007155 110 0.049
tissue development GO:0009888 252 0.045
regulation of cell differentiation GO:0045595 320 0.045
reproduction GO:0000003 245 0.044
lymphocyte activation GO:0046649 43 0.044
regulation of neuron projection development GO:0010975 161 0.043
regulation of cellular amino acid metabolic process GO:0006521 2 0.043
response to monosaccharide GO:0034284 159 0.042
regulation of cell activation GO:0050865 50 0.039
cellular response to growth factor stimulus GO:0071363 162 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
leukocyte activation GO:0045321 76 0.038
regulation of cellular component organization GO:0051128 368 0.037
response to external biotic stimulus GO:0043207 221 0.037
response to reactive oxygen species GO:0000302 120 0.037
acute inflammatory response GO:0002526 58 0.037
response to estrogen GO:0043627 232 0.036
cation transport GO:0006812 382 0.035
central nervous system development GO:0007417 311 0.035
reproductive process GO:0022414 372 0.035
cytokine production GO:0001816 61 0.035
negative regulation of programmed cell death GO:0043069 183 0.034
cellular response to stress GO:0033554 269 0.034
cellular response to oxygen containing compound GO:1901701 386 0.033
response to inorganic substance GO:0010035 377 0.032
multi organism reproductive process GO:0044703 262 0.031
oxoacid metabolic process GO:0043436 290 0.031
reproductive structure development GO:0048608 128 0.030
female pregnancy GO:0007565 122 0.030
cell projection organization GO:0030030 302 0.030
circulatory system process GO:0003013 183 0.029
activation of immune response GO:0002253 26 0.029
urogenital system development GO:0001655 78 0.029
cell cell signaling GO:0007267 335 0.029
blood circulation GO:0008015 183 0.029
monocarboxylic acid metabolic process GO:0032787 152 0.029
vesicle mediated transport GO:0016192 181 0.028
response to glucocorticoid GO:0051384 223 0.028
regulation of leukocyte activation GO:0002694 45 0.028
regulation of multicellular organismal development GO:2000026 376 0.027
cell projection morphogenesis GO:0048858 123 0.027
response to bacterium GO:0009617 200 0.027
catabolic process GO:0009056 351 0.027
multicellular organismal homeostasis GO:0048871 49 0.026
negative regulation of cell proliferation GO:0008285 119 0.026
regulation of immune response GO:0050776 55 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
mast cell degranulation GO:0043303 10 0.026
cellular amine metabolic process GO:0044106 38 0.026
eosinophil chemotaxis GO:0048245 3 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
neuron development GO:0048666 286 0.025
response to glucose GO:0009749 136 0.025
amine metabolic process GO:0009308 38 0.025
cell type specific apoptotic process GO:0097285 134 0.024
developmental process involved in reproduction GO:0003006 159 0.024
male mating behavior GO:0060179 3 0.024
regulation of neurogenesis GO:0050767 247 0.024
nucleic acid templated transcription GO:0097659 379 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
response to oxidative stress GO:0006979 186 0.023
regulation of system process GO:0044057 208 0.023
response to hexose GO:0009746 144 0.023
response to nutrient GO:0007584 248 0.023
regulation of catalytic activity GO:0050790 304 0.023
response to carbohydrate GO:0009743 183 0.023
response to ethanol GO:0045471 162 0.022
response to vitamin GO:0033273 131 0.022
positive regulation of biomineral tissue development GO:0070169 4 0.022
regulation of vesicle mediated transport GO:0060627 81 0.022
organelle organization GO:0006996 266 0.022
response to peptide hormone GO:0043434 278 0.022
gamete generation GO:0007276 124 0.022
growth GO:0040007 165 0.022
regulation of cell adhesion GO:0030155 52 0.021
reproductive system development GO:0061458 128 0.021
bone remodeling GO:0046849 23 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
secretion GO:0046903 307 0.020
response to peptide GO:1901652 292 0.020
macrophage chemotaxis GO:0048246 2 0.020
response to gonadotropin GO:0034698 34 0.019
negative regulation of neutrophil apoptotic process GO:0033030 3 0.019
tissue remodeling GO:0048771 40 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of ion transport GO:0043269 245 0.019
cellular ketone metabolic process GO:0042180 51 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
positive regulation of molecular function GO:0044093 230 0.019
response to lipopolysaccharide GO:0032496 191 0.019
cellular response to alcohol GO:0097306 87 0.018
positive regulation of cell motility GO:2000147 97 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
organ regeneration GO:0031100 101 0.018
regulation of cell development GO:0060284 263 0.018
taxis GO:0042330 67 0.018
response to biotic stimulus GO:0009607 226 0.018
oligopeptide transport GO:0006857 4 0.018
maternal process involved in female pregnancy GO:0060135 38 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.018
positive regulation of transport GO:0051050 245 0.018
ion transmembrane transport GO:0034220 365 0.018
positive regulation of leukocyte migration GO:0002687 21 0.017
regulation of phosphorylation GO:0042325 248 0.017
response to decreased oxygen levels GO:0036293 237 0.017
regulation of molecular function GO:0065009 398 0.017
cell migration GO:0016477 197 0.017
positive regulation of cell development GO:0010720 176 0.017
immune effector process GO:0002252 53 0.017
regulation of cytokine production GO:0001817 56 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
intracellular signal transduction GO:0035556 314 0.017
response to growth factor GO:0070848 189 0.017
insecticide metabolic process GO:0017143 4 0.017
intracellular transport GO:0046907 185 0.017
response to oxygen levels GO:0070482 265 0.016
cell growth GO:0016049 104 0.016
apoptotic process GO:0006915 381 0.016
regulation of b cell mediated immunity GO:0002712 2 0.016
regulation of cell proliferation GO:0042127 359 0.016
male gamete generation GO:0048232 99 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
response to radiation GO:0009314 137 0.016
neuron death GO:0070997 127 0.016
metal ion transport GO:0030001 289 0.016
neutrophil migration GO:1990266 12 0.015
single organism catabolic process GO:0044712 283 0.015
single organism cell adhesion GO:0098602 46 0.015
ossification GO:0001503 70 0.015
cation transmembrane transport GO:0098655 263 0.015
spermatogenesis GO:0007283 99 0.015
response to tumor necrosis factor GO:0034612 56 0.015
rhythmic process GO:0048511 156 0.015
regulation of nervous system development GO:0051960 264 0.015
organic anion transport GO:0015711 132 0.015
neutrophil chemotaxis GO:0030593 11 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cellular component assembly GO:0022607 360 0.015
response to other organism GO:0051707 220 0.015
response to hydrogen peroxide GO:0042542 89 0.014
cellular component movement GO:0006928 248 0.014
cellular response to lipid GO:0071396 201 0.014
positive regulation of cell migration GO:0030335 96 0.014
development of primary sexual characteristics GO:0045137 107 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
positive regulation of nervous system development GO:0051962 178 0.014
response to hypoxia GO:0001666 231 0.014
female sex differentiation GO:0046660 59 0.014
response to wounding GO:0009611 254 0.014
bone resorption GO:0045453 18 0.014
regulation of cellular component movement GO:0051270 150 0.014
chemical homeostasis GO:0048878 292 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
organic acid metabolic process GO:0006082 292 0.014
cellular catabolic process GO:0044248 295 0.013
cellular chemical homeostasis GO:0055082 247 0.013
protein complex subunit organization GO:0071822 302 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
single organism biosynthetic process GO:0044711 342 0.013
synaptic transmission GO:0007268 235 0.013
cellular lipid metabolic process GO:0044255 208 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 7 0.013
secretion by cell GO:0032940 248 0.013
negative regulation of neuron differentiation GO:0045665 62 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
neuron projection morphogenesis GO:0048812 122 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
proline transport GO:0015824 3 0.012
proteolysis GO:0006508 175 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of leukocyte migration GO:0002685 24 0.012
mononuclear cell migration GO:0071674 3 0.012
action potential GO:0001508 54 0.012
neuron apoptotic process GO:0051402 88 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
glial cell differentiation GO:0010001 65 0.012
regulation of response to stress GO:0080134 126 0.012
response to metal ion GO:0010038 253 0.012
striated muscle tissue development GO:0014706 58 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of response to external stimulus GO:0032101 106 0.011
cellular homeostasis GO:0019725 252 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
positive regulation of secretion GO:0051047 140 0.011
positive regulation of angiogenesis GO:0045766 28 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of secretion by cell GO:1903530 208 0.011
anatomical structure homeostasis GO:0060249 29 0.011
regulation of tube size GO:0035150 89 0.011
ovulation cycle GO:0042698 67 0.011
transmembrane transport GO:0055085 412 0.011
positive regulation of defense response GO:0031349 37 0.011
anion transport GO:0006820 178 0.011
response to cytokine GO:0034097 215 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of muscle cell apoptotic process GO:0010660 26 0.010
leukocyte cell cell adhesion GO:0007159 4 0.010
response to alkaloid GO:0043279 132 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
regulation of acute inflammatory response GO:0002673 23 0.010
granulocyte migration GO:0097530 16 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
placenta development GO:0001890 22 0.010
lipid transport GO:0006869 61 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010

Gpnmb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.013