Rattus norvegicus

82 known processes

Wnk1

WNK lysine deficient protein kinase 1

(Aliases: Hsn2,Prkwnk1)

Wnk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.091
regulation of rna metabolic process GO:0051252 391 0.078
transcription dna templated GO:0006351 377 0.065
regulation of transcription dna templated GO:0006355 374 0.061
nucleic acid templated transcription GO:0097659 379 0.057
positive regulation of biosynthetic process GO:0009891 319 0.056
regulation of cellular component organization GO:0051128 368 0.051
regulation of rna biosynthetic process GO:2001141 381 0.050
regulation of nucleic acid templated transcription GO:1903506 380 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
anterior posterior pattern specification GO:0009952 1 0.046
rna biosynthetic process GO:0032774 380 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.042
positive regulation of gene expression GO:0010628 244 0.041
secretion by cell GO:0032940 248 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
regulation of secretion GO:0051046 224 0.036
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.036
macromolecular complex subunit organization GO:0043933 339 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
amine metabolic process GO:0009308 38 0.033
regulation of cellular localization GO:0060341 263 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
cellular ketone metabolic process GO:0042180 51 0.031
organelle organization GO:0006996 266 0.031
regulation of molecular function GO:0065009 398 0.031
cellular response to stress GO:0033554 269 0.030
secretion GO:0046903 307 0.030
Mouse
cellular amine metabolic process GO:0044106 38 0.030
rna metabolic process GO:0016070 406 0.030
negative regulation of metabolic process GO:0009892 331 0.030
negative regulation of transport GO:0051051 136 0.030
Mouse
regulation of cell proliferation GO:0042127 359 0.029
positive regulation of transcription dna templated GO:0045893 197 0.029
regulation of secretion by cell GO:1903530 208 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
mesoderm development GO:0007498 2 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
vesicle mediated transport GO:0016192 181 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
negative regulation of gene expression GO:0010629 199 0.026
positive regulation of transport GO:0051050 245 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
cellular component biogenesis GO:0044085 368 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
cell projection organization GO:0030030 302 0.024
Fly
regulation of cell differentiation GO:0045595 320 0.024
regulation of neuron differentiation GO:0045664 208 0.024
cellular response to oxygen containing compound GO:1901701 386 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
chemical homeostasis GO:0048878 292 0.023
homeostatic process GO:0042592 331 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of signaling GO:0023056 270 0.022
Fly
axis specification GO:0009798 4 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
oxoacid metabolic process GO:0043436 290 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
hormone transport GO:0009914 121 0.021
cellular chemical homeostasis GO:0055082 247 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of signal transduction GO:0009966 318 0.020
Fly
embryonic pattern specification GO:0009880 1 0.020
cellular macromolecule localization GO:0070727 122 0.020
protein phosphorylation GO:0006468 345 0.020
neuron projection development GO:0031175 273 0.020
Fly
intracellular signal transduction GO:0035556 314 0.020
regulation of peptide transport GO:0090087 87 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of developmental process GO:0051094 283 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
cation transport GO:0006812 382 0.020
metal ion homeostasis GO:0055065 186 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
apoptotic process GO:0006915 381 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
single organism organelle organization GO:1902589 180 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
protein complex subunit organization GO:0071822 302 0.019
response to nutrient levels GO:0031667 370 0.019
multi organism reproductive process GO:0044703 262 0.019
Worm
organic acid metabolic process GO:0006082 292 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
regulation of apoptotic process GO:0042981 335 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of secretion by cell GO:1903532 128 0.018
head development GO:0060322 247 0.018
cellular component assembly GO:0022607 360 0.018
tissue development GO:0009888 252 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
cellular ion homeostasis GO:0006873 184 0.017
positive regulation of cell development GO:0010720 176 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
Worm
nucleotide metabolic process GO:0009117 279 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
central nervous system development GO:0007417 311 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of programmed cell death GO:0043067 341 0.017
regulation of protein modification process GO:0031399 194 0.017
cellular cation homeostasis GO:0030003 180 0.017
ion homeostasis GO:0050801 212 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
brain development GO:0007420 247 0.016
macromolecule localization GO:0033036 252 0.016
positive regulation of cell communication GO:0010647 271 0.016
Fly
cation homeostasis GO:0055080 195 0.016
single organism biosynthetic process GO:0044711 342 0.016
negative regulation of developmental process GO:0051093 125 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
regulation of protein metabolic process GO:0051246 289 0.016
regulation of peptide secretion GO:0002791 82 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
cellular homeostasis GO:0019725 252 0.016
endocytosis GO:0006897 84 0.016
embryonic axis specification GO:0000578 1 0.016
positive regulation of secretion GO:0051047 140 0.016
regulation of hormone secretion GO:0046883 106 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
intracellular transport GO:0046907 185 0.015
gastrulation GO:0007369 2 0.015
regulation of catalytic activity GO:0050790 304 0.015
organophosphate metabolic process GO:0019637 370 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
macromolecular complex assembly GO:0065003 273 0.015
regulation of organelle organization GO:0033043 80 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
gland development GO:0048732 155 0.014
nitrogen compound transport GO:0071705 229 0.014
aromatic compound catabolic process GO:0019439 168 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
response to growth factor GO:0070848 189 0.014
exocytosis GO:0006887 60 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
response to nutrient GO:0007584 248 0.014
response to inorganic substance GO:0010035 377 0.014
calcium ion homeostasis GO:0055074 162 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
Fly
positive regulation of cell death GO:0010942 184 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
circulatory system development GO:0072359 134 0.014
response to extracellular stimulus GO:0009991 380 0.014
cell cell signaling GO:0007267 335 0.014
regulation of neuron projection development GO:0010975 161 0.014
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
neurological system process GO:0050877 219 0.013
single organism reproductive process GO:0044702 297 0.013
hormone secretion GO:0046879 115 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
negative regulation of secretion GO:0051048 82 0.013
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.013
purine containing compound metabolic process GO:0072521 253 0.013
reproductive process GO:0022414 372 0.013
Worm
response to decreased oxygen levels GO:0036293 237 0.013
negative regulation of cell death GO:0060548 229 0.013
cell cycle GO:0007049 101 0.013
lipid metabolic process GO:0006629 283 0.013
signal release GO:0023061 145 0.013
programmed cell death GO:0012501 392 0.013
cellular response to growth factor stimulus GO:0071363 162 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
response to glucose GO:0009749 136 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
metal ion transport GO:0030001 289 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of embryonic development GO:0045995 2 0.012
multicellular organism reproduction GO:0032504 233 0.012
Worm
small gtpase mediated signal transduction GO:0007264 36 0.012
amide transport GO:0042886 105 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of phosphorylation GO:0042325 248 0.012
single organism intracellular transport GO:1902582 166 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
peptide hormone secretion GO:0030072 84 0.012
cellular component movement GO:0006928 248 0.012
Fly
calcium ion transport GO:0006816 131 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
cellular calcium ion homeostasis GO:0006874 160 0.011
insulin secretion GO:0030073 69 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
negative regulation of cell communication GO:0010648 158 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
gamete generation GO:0007276 124 0.011
response to bacterium GO:0009617 200 0.011
response to estradiol GO:0032355 164 0.011
peptide secretion GO:0002790 86 0.011
divalent inorganic cation transport GO:0072511 134 0.011
response to wounding GO:0009611 254 0.011
proteolysis GO:0006508 175 0.011
negative regulation of signaling GO:0023057 157 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
developmental process involved in reproduction GO:0003006 159 0.011
cardiovascular system development GO:0072358 134 0.011
actin filament based process GO:0030029 86 0.011
rna localization GO:0006403 4 0.011
peptide transport GO:0015833 97 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
Mouse
neuron development GO:0048666 286 0.011
Fly
regulation of anatomical structure size GO:0090066 135 0.011
sexual reproduction GO:0019953 148 0.011
response to metal ion GO:0010038 253 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
Fly
regulation of ion transport GO:0043269 245 0.011
chromatin modification GO:0016568 33 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
oxidation reduction process GO:0055114 304 0.010
ras protein signal transduction GO:0007265 29 0.010
cation transmembrane transport GO:0098655 263 0.010
cellular component morphogenesis GO:0032989 155 0.010
Fly
positive regulation of protein modification process GO:0031401 142 0.010
carbohydrate metabolic process GO:0005975 130 0.010
regulation of cell projection organization GO:0031344 175 0.010
dna metabolic process GO:0006259 96 0.010
neuron differentiation GO:0030182 368 0.010
Fly
regulation of growth GO:0040008 105 0.010
response to peptide hormone GO:0043434 278 0.010
regulation of insulin secretion GO:0050796 65 0.010
regulation of membrane potential GO:0042391 110 0.010
regulation of hormone levels GO:0010817 187 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
formation of primary germ layer GO:0001704 1 0.010

Wnk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
Human
nervous system disease DOID:863 0 0.019
Human
sensory system disease DOID:0050155 0 0.013