Rattus norvegicus

136 known processes

Srebf1

sterol regulatory element binding transcription factor 1

(Aliases: Srebp1,ADD-1)

Srebf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor metabolic process GO:0051186 95 0.453
cellular lipid metabolic process GO:0044255 208 0.423
Mouse
lipid metabolic process GO:0006629 283 0.422
organic acid metabolic process GO:0006082 292 0.422
Mouse
regulation of lipid metabolic process GO:0019216 68 0.391
Mouse
coenzyme metabolic process GO:0006732 86 0.342
carboxylic acid metabolic process GO:0019752 289 0.229
Mouse
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.217
Mouse
cellular response to peptide hormone stimulus GO:0071375 120 0.184
fatty acid biosynthetic process GO:0006633 33 0.181
acyl coa metabolic process GO:0006637 28 0.177
cellular response to organonitrogen compound GO:0071417 197 0.174
monocarboxylic acid biosynthetic process GO:0072330 48 0.171
cellular response to peptide GO:1901653 133 0.137
single organism biosynthetic process GO:0044711 342 0.136
Mouse
lipid biosynthetic process GO:0008610 128 0.126
Mouse
ensheathment of neurons GO:0007272 40 0.124
response to peptide GO:1901652 292 0.118
nucleic acid templated transcription GO:0097659 379 0.115
neurological system process GO:0050877 219 0.115
oxoacid metabolic process GO:0043436 290 0.114
Mouse
carbohydrate metabolic process GO:0005975 130 0.109
action potential GO:0001508 54 0.106
response to insulin GO:0032868 133 0.104
sulfur compound metabolic process GO:0006790 70 0.102
transmission of nerve impulse GO:0019226 42 0.099
carboxylic acid biosynthetic process GO:0046394 83 0.095
cell cell signaling GO:0007267 335 0.095
Mouse
transcription dna templated GO:0006351 377 0.094
cellular response to insulin stimulus GO:0032869 81 0.089
regulation of triglyceride biosynthetic process GO:0010866 4 0.087
Mouse
multicellular organismal signaling GO:0035637 44 0.086
secretion by cell GO:0032940 248 0.086
Mouse
monocarboxylic acid metabolic process GO:0032787 152 0.085
Mouse
rna biosynthetic process GO:0032774 380 0.085
regulation of multicellular organismal development GO:2000026 376 0.085
regulation of cell proliferation GO:0042127 359 0.085
response to peptide hormone GO:0043434 278 0.083
negative regulation of multicellular organismal process GO:0051241 203 0.080
axon ensheathment GO:0008366 40 0.074
microvillus assembly GO:0030033 2 0.074
response to biotic stimulus GO:0009607 226 0.074
rna metabolic process GO:0016070 406 0.074
response to estradiol GO:0032355 164 0.072
secretion GO:0046903 307 0.072
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.071
Human Mouse Rat
regulation of transcription dna templated GO:0006355 374 0.070
metal ion transport GO:0030001 289 0.070
acetyl coa metabolic process GO:0006084 17 0.070
organic acid biosynthetic process GO:0016053 83 0.066
positive regulation of biosynthetic process GO:0009891 319 0.064
positive regulation of developmental process GO:0051094 283 0.064
neuronal action potential GO:0019228 35 0.063
regulation of nervous system development GO:0051960 264 0.063
small molecule biosynthetic process GO:0044283 124 0.062
Mouse
reproductive process GO:0022414 372 0.062
Rat
regulation of rna biosynthetic process GO:2001141 381 0.061
cellular response to oxygen containing compound GO:1901701 386 0.060
enzyme linked receptor protein signaling pathway GO:0007167 116 0.060
Mouse
myelination GO:0042552 39 0.060
negative regulation of cell differentiation GO:0045596 99 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
cellular amino acid metabolic process GO:0006520 107 0.057
response to external biotic stimulus GO:0043207 221 0.057
negative regulation of rna metabolic process GO:0051253 123 0.057
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.055
negative regulation of metabolic process GO:0009892 331 0.055
Mouse
cellular response to hormone stimulus GO:0032870 247 0.054
gliogenesis GO:0042063 93 0.054
cellular response to nitrogen compound GO:1901699 210 0.054
regulation of plasma lipoprotein particle levels GO:0097006 3 0.053
regulation of neuron differentiation GO:0045664 208 0.053
cell cycle GO:0007049 101 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
Mouse
chemical homeostasis GO:0048878 292 0.053
regulation of mesenchymal cell proliferation GO:0010464 4 0.052
glial cell differentiation GO:0010001 65 0.052
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.052
mesenchymal cell proliferation GO:0010463 4 0.052
regulation of membrane potential GO:0042391 110 0.051
positive regulation of triglyceride metabolic process GO:0090208 4 0.050
Mouse
homeostatic process GO:0042592 331 0.050
thioester metabolic process GO:0035383 28 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.049
Mouse
negative regulation of developmental process GO:0051093 125 0.047
monosaccharide metabolic process GO:0005996 61 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
regulation of signal transduction GO:0009966 318 0.046
regulation of neurogenesis GO:0050767 247 0.046
multi organism reproductive process GO:0044703 262 0.046
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.046
gland development GO:0048732 155 0.046
response to other organism GO:0051707 220 0.045
anion transport GO:0006820 178 0.045
central nervous system development GO:0007417 311 0.045
regulation of cell differentiation GO:0045595 320 0.045
tube development GO:0035295 89 0.044
positive regulation of transcription dna templated GO:0045893 197 0.044
negative regulation of cell proliferation GO:0008285 119 0.044
biological adhesion GO:0022610 110 0.044
amine metabolic process GO:0009308 38 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.043
catabolic process GO:0009056 351 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
Human Mouse Rat
negative regulation of nervous system development GO:0051961 79 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.042
Human Mouse Rat
single organism carbohydrate metabolic process GO:0044723 118 0.042
anatomical structure morphogenesis GO:0009653 298 0.042
blood circulation GO:0008015 183 0.041
Mouse
response to nutrient levels GO:0031667 370 0.041
regulation of lipid biosynthetic process GO:0046890 38 0.041
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
negative regulation of cell development GO:0010721 82 0.040
reproduction GO:0000003 245 0.040
Rat
cation transport GO:0006812 382 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.040
cellular ketone metabolic process GO:0042180 51 0.039
Mouse
cellular amine metabolic process GO:0044106 38 0.039
triglyceride metabolic process GO:0006641 21 0.038
Mouse
positive regulation of gene expression GO:0010628 244 0.038
macromolecule localization GO:0033036 252 0.038
locomotion GO:0040011 237 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.038
Mouse
regulation of rna metabolic process GO:0051252 391 0.038
behavior GO:0007610 205 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.038
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.037
positive regulation of cell development GO:0010720 176 0.037
positive regulation of nervous system development GO:0051962 178 0.037
negative regulation of protein import into nucleus translocation GO:0033159 1 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
brain development GO:0007420 247 0.037
response to extracellular stimulus GO:0009991 380 0.037
response to acid chemical GO:0001101 222 0.036
heart morphogenesis GO:0003007 3 0.036
response to inorganic substance GO:0010035 377 0.035
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
regulation of cell development GO:0060284 263 0.035
response to estrogen GO:0043627 232 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
Rat
negative regulation of transcription dna templated GO:0045892 116 0.035
Mouse
organic substance catabolic process GO:1901575 316 0.035
sensory perception GO:0007600 101 0.035
multicellular organism growth GO:0035264 1 0.034
regulation of catalytic activity GO:0050790 304 0.034
positive regulation of lipid biosynthetic process GO:0046889 25 0.034
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.034
Mouse
response to wounding GO:0009611 254 0.033
anion transmembrane transport GO:0098656 77 0.033
protein targeting GO:0006605 61 0.033
response to bacterium GO:0009617 200 0.033
carboxylic acid transport GO:0046942 115 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
Mouse
lipid storage GO:0019915 1 0.032
neutral lipid metabolic process GO:0006638 21 0.032
Mouse
regulation of hormone levels GO:0010817 187 0.032
Mouse
response to vitamin GO:0033273 131 0.032
single organism catabolic process GO:0044712 283 0.032
multi multicellular organism process GO:0044706 138 0.031
regulation of cell projection organization GO:0031344 175 0.031
lipid modification GO:0030258 52 0.031
regulation of ion transport GO:0043269 245 0.031
prostate gland epithelium morphogenesis GO:0060740 2 0.031
protein transport GO:0015031 132 0.031
proteolysis GO:0006508 175 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.030
Mouse
multicellular organism reproduction GO:0032504 233 0.030
Rat
organic hydroxy compound transport GO:0015850 77 0.030
cellular catabolic process GO:0044248 295 0.030
regulation of immune system process GO:0002682 123 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
Mouse
ion homeostasis GO:0050801 212 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
Mouse
germ cell migration GO:0008354 1 0.029
nicotinamide nucleotide metabolic process GO:0046496 28 0.029
regulation of canonical wnt signaling pathway GO:0060828 4 0.028
regulation of molecular function GO:0065009 398 0.028
renal system development GO:0072001 67 0.028
cell projection organization GO:0030030 302 0.027
regulation of cell cycle GO:0051726 73 0.027
regulation of cellular component organization GO:0051128 368 0.027
Mouse
fatty acid transmembrane transport GO:1902001 3 0.027
regulation of kinase activity GO:0043549 117 0.027
lipid localization GO:0010876 62 0.026
positive regulation of lipid metabolic process GO:0045834 33 0.026
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.026
insulin like growth factor receptor signaling pathway GO:0048009 3 0.026
oxidation reduction process GO:0055114 304 0.026
neuron projection development GO:0031175 273 0.026
organic anion transport GO:0015711 132 0.025
regulation of protein metabolic process GO:0051246 289 0.025
Mouse
hexose metabolic process GO:0019318 58 0.025
negative regulation of neurogenesis GO:0050768 78 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
acylglycerol metabolic process GO:0006639 21 0.025
Mouse
tissue development GO:0009888 252 0.025
aging GO:0007568 241 0.025
response to retinoic acid GO:0032526 63 0.024
vesicle mediated transport GO:0016192 181 0.024
negative regulation of gene expression GO:0010629 199 0.024
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
Mouse
regulation of neuron projection development GO:0010975 161 0.024
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.024
transmembrane transport GO:0055085 412 0.024
synaptic transmission GO:0007268 235 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
fatty acid metabolic process GO:0006631 99 0.024
Mouse
prostate gland morphogenesis GO:0060512 2 0.024
single organism nuclear import GO:1902593 35 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.023
single organism carbohydrate catabolic process GO:0044724 40 0.023
nucleotide metabolic process GO:0009117 279 0.023
salivary gland development GO:0007431 3 0.023
long chain fatty acid metabolic process GO:0001676 32 0.023
glycerol 3 phosphate metabolic process GO:0006072 2 0.023
cellular response to stress GO:0033554 269 0.023
cellular carbohydrate metabolic process GO:0044262 72 0.023
neutral lipid biosynthetic process GO:0046460 7 0.023
Mouse
hormone metabolic process GO:0042445 69 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
Mouse
positive regulation of neuron projection development GO:0010976 99 0.023
peptidyl amino acid modification GO:0018193 126 0.023
cellular component assembly GO:0022607 360 0.022
cellular polysaccharide metabolic process GO:0044264 23 0.022
cellular component biogenesis GO:0044085 368 0.022
divalent metal ion transport GO:0070838 132 0.022
single organism intracellular transport GO:1902582 166 0.022
protein import GO:0017038 37 0.022
protein phosphorylation GO:0006468 345 0.022
head development GO:0060322 247 0.021
response to nutrient GO:0007584 248 0.021
response to activity GO:0014823 73 0.021
single organism reproductive process GO:0044702 297 0.021
Rat
regulation of calcium ion transport GO:0051924 77 0.021
cation homeostasis GO:0055080 195 0.021
salivary gland morphogenesis GO:0007435 1 0.021
organic acid transport GO:0015849 116 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
Mouse
activation of jak2 kinase activity GO:0042977 2 0.021
regeneration GO:0031099 163 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
cardiovascular system development GO:0072358 134 0.021
defense response GO:0006952 194 0.021
regulation of secretion GO:0051046 224 0.021
Mouse
establishment of protein localization to organelle GO:0072594 44 0.021
cell morphogenesis GO:0000902 142 0.021
neuron development GO:0048666 286 0.021
dendrite development GO:0016358 72 0.020
response to vitamin d GO:0033280 34 0.020
cytoplasmic transport GO:0016482 115 0.020
regulation of response to external stimulus GO:0032101 106 0.020
glucose metabolic process GO:0006006 52 0.020
glycerolipid metabolic process GO:0046486 67 0.020
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
cellular response to external stimulus GO:0071496 118 0.020
endocytosis GO:0006897 84 0.020
cerebral cortex cell migration GO:0021795 4 0.020
camera type eye development GO:0043010 48 0.020
hepaticobiliary system development GO:0061008 90 0.020
regulation of system process GO:0044057 208 0.020
Mouse
positive regulation of molecular function GO:0044093 230 0.020
regulation of catabolic process GO:0009894 113 0.019
negative regulation of transport GO:0051051 136 0.019
Mouse
developmental induction GO:0031128 2 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
macromolecular complex assembly GO:0065003 273 0.019
cellular response to lipid GO:0071396 201 0.019
heart development GO:0007507 72 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
organophosphate metabolic process GO:0019637 370 0.019
inflammatory response GO:0006954 150 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
regulation of gluconeogenesis GO:0006111 4 0.019
regulation of intracellular signal transduction GO:1902531 218 0.018
glucan metabolic process GO:0044042 23 0.018
cellular component movement GO:0006928 248 0.018
immune system process GO:0002376 204 0.018
negative regulation of molecular function GO:0044092 133 0.018
growth GO:0040007 165 0.018
response to monosaccharide GO:0034284 159 0.018
Mouse
regulation of transferase activity GO:0051338 123 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cellular hormone metabolic process GO:0034754 49 0.018
regulation of protein modification process GO:0031399 194 0.018
Mouse
plasma lipoprotein particle clearance GO:0034381 3 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
ion transmembrane transport GO:0034220 365 0.017
negative regulation of signaling GO:0023057 157 0.017
Mouse
appendage morphogenesis GO:0035107 4 0.017
circulatory system development GO:0072359 134 0.017
apoptotic process GO:0006915 381 0.017
circulatory system process GO:0003013 183 0.017
Mouse
developmental process involved in reproduction GO:0003006 159 0.017
localization of cell GO:0051674 202 0.017
lipid oxidation GO:0034440 30 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
positive regulation of kinase activity GO:0033674 77 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.017
response to lipopolysaccharide GO:0032496 191 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
intracellular receptor signaling pathway GO:0030522 35 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
Mouse
neuron differentiation GO:0030182 368 0.016
embryonic limb morphogenesis GO:0030326 4 0.016
protein localization to organelle GO:0033365 57 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
response to glucose GO:0009749 136 0.016
Mouse
protein autophosphorylation GO:0046777 66 0.016
female pregnancy GO:0007565 122 0.016
carbohydrate biosynthetic process GO:0016051 42 0.016
regulation of plasma membrane long chain fatty acid transport GO:0010746 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cellular protein localization GO:0034613 122 0.016
nitrogen compound transport GO:0071705 229 0.016
Mouse
regulation of metal ion transport GO:0010959 118 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of activation of jak2 kinase activity GO:0010534 1 0.016
protein targeting to nucleus GO:0044744 35 0.016
phagocytosis GO:0006909 17 0.016
cell part morphogenesis GO:0032990 123 0.016
establishment of tissue polarity GO:0007164 2 0.016
regulation of cellular localization GO:0060341 263 0.016
Mouse
negative regulation of cellular component organization GO:0051129 83 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
Mouse
response to growth factor GO:0070848 189 0.016
intracellular transport GO:0046907 185 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
response to corticosteroid GO:0031960 235 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
negative regulation of neuron death GO:1901215 69 0.015
cerebral cortex development GO:0021987 18 0.015
specification of organ identity GO:0010092 2 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
rhythmic process GO:0048511 156 0.015
Mouse
intracellular signal transduction GO:0035556 314 0.015
establishment of protein localization GO:0045184 141 0.015
positive regulation of protein modification process GO:0031401 142 0.015
Mouse
muscle cell proliferation GO:0033002 84 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
protein complex assembly GO:0006461 263 0.015
hormone biosynthetic process GO:0042446 25 0.015
hair cell differentiation GO:0035315 2 0.015
calcium ion transport GO:0006816 131 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
mechanoreceptor differentiation GO:0042490 2 0.015
lung development GO:0030324 43 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
fatty acid oxidation GO:0019395 29 0.015
formation of primary germ layer GO:0001704 1 0.015
single organism membrane organization GO:0044802 74 0.015
cellular homeostasis GO:0019725 252 0.015
response to metal ion GO:0010038 253 0.015
Rat
response to ethanol GO:0045471 162 0.015
regulation of phosphorylation GO:0042325 248 0.014
eye development GO:0001654 50 0.014
cellular response to acid chemical GO:0071229 75 0.014
negative regulation of osteoblast differentiation GO:0045668 2 0.014
negative regulation of phosphorylation GO:0042326 57 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of carbohydrate metabolic process GO:0006109 41 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
circadian rhythm GO:0007623 88 0.014
Mouse
acylglycerol biosynthetic process GO:0046463 7 0.014
Mouse
regulation of protein secretion GO:0050708 28 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of growth GO:0040008 105 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
gamete generation GO:0007276 124 0.014
Rat
negative regulation of cell communication GO:0010648 158 0.014
Mouse
response to disaccharide GO:0034285 10 0.014
energy reserve metabolic process GO:0006112 25 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
sterol homeostasis GO:0055092 3 0.014
regulation of blood pressure GO:0008217 83 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
retinoic acid receptor signaling pathway GO:0048384 7 0.014
ras protein signal transduction GO:0007265 29 0.014
response to vitamin a GO:0033189 36 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
protein complex biogenesis GO:0070271 263 0.013
male mating behavior GO:0060179 3 0.013
glycogen biosynthetic process GO:0005978 15 0.013
cell migration GO:0016477 197 0.013
regulation of anatomical structure size GO:0090066 135 0.013
single organism behavior GO:0044708 130 0.013
udp glucose metabolic process GO:0006011 3 0.013
regulation of protein kinase activity GO:0045859 105 0.013
carbohydrate homeostasis GO:0033500 75 0.013
regulation of apoptotic process GO:0042981 335 0.013
male gamete generation GO:0048232 99 0.013
Rat
spermatogenesis GO:0007283 99 0.013
Rat
regulation of cell growth GO:0001558 85 0.013
sex differentiation GO:0007548 113 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
cell projection morphogenesis GO:0048858 123 0.013
digestive system development GO:0055123 41 0.013
cell fate determination GO:0001709 2 0.013
regulation of ossification GO:0030278 32 0.013
protein oligomerization GO:0051259 191 0.013
reproductive structure development GO:0048608 128 0.013
maintenance of location GO:0051235 17 0.013
glandular epithelial cell differentiation GO:0002067 4 0.013
positive regulation of epithelial cell proliferation GO:0050679 32 0.013
macromolecule catabolic process GO:0009057 58 0.013
positive regulation of transferase activity GO:0051347 81 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
neuron death GO:0070997 127 0.012
metal ion homeostasis GO:0055065 186 0.012
jak stat cascade GO:0007259 26 0.012
regulation of lipid storage GO:0010883 1 0.012
cellular ion homeostasis GO:0006873 184 0.012
positive regulation of cell communication GO:0010647 271 0.012
response to axon injury GO:0048678 59 0.012
urogenital system development GO:0001655 78 0.012
regulation of translation GO:0006417 27 0.012
activation of protein kinase b activity GO:0032148 3 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
cardiac chamber development GO:0003205 1 0.012
camera type eye morphogenesis GO:0048593 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
eye morphogenesis GO:0048592 4 0.012
cell growth GO:0016049 104 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
reproductive system development GO:0061458 128 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
polysaccharide metabolic process GO:0005976 25 0.012
regulation of programmed cell death GO:0043067 341 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
response to toxic substance GO:0009636 133 0.012
cell differentiation involved in kidney development GO:0061005 4 0.012
regulation of response to stress GO:0080134 126 0.012
regulation of defense response GO:0031347 68 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
Mouse
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
respiratory system development GO:0060541 45 0.012
organ formation GO:0048645 3 0.012
gastrulation GO:0007369 2 0.011
positive regulation of fatty acid beta oxidation GO:0032000 4 0.011
cellular macromolecule localization GO:0070727 122 0.011
lipid transport GO:0006869 61 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
mitotic cell cycle GO:0000278 49 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of blood vessel size GO:0050880 89 0.011
cell projection assembly GO:0030031 21 0.011
limb morphogenesis GO:0035108 4 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
liver development GO:0001889 90 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
epithelial cell differentiation involved in kidney development GO:0035850 3 0.011
organelle organization GO:0006996 266 0.011
Mouse
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
negative regulation of cell death GO:0060548 229 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
protein localization GO:0008104 191 0.011
organic acid catabolic process GO:0016054 49 0.011
regulation of response to wounding GO:1903034 69 0.011
vascular process in circulatory system GO:0003018 96 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cellular glucan metabolic process GO:0006073 23 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of synaptic transmission GO:0050804 141 0.011
regulation of cell migration GO:0030334 128 0.011
organ induction GO:0001759 1 0.011
response to mechanical stimulus GO:0009612 134 0.011
protein localization to nucleus GO:0034504 39 0.011
negative regulation of secretion GO:0051048 82 0.011
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
axis specification GO:0009798 4 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of secretion by cell GO:1903530 208 0.011
Mouse
nucleotide biosynthetic process GO:0009165 98 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
sensory organ development GO:0007423 74 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011

Srebf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.034
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
connective tissue disease DOID:65 0 0.031
nervous system disease DOID:863 0 0.030
inherited metabolic disorder DOID:655 0 0.018
gastrointestinal system disease DOID:77 0 0.014
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011