Rattus norvegicus

0 known processes

Phlda2

pleckstrin homology-like domain, family A, member 2

Phlda2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.086
negative regulation of metabolic process GO:0009892 331 0.082
response to extracellular stimulus GO:0009991 380 0.071
locomotion GO:0040011 237 0.071
response to nutrient GO:0007584 248 0.067
regulation of cellular component organization GO:0051128 368 0.066
macromolecular complex subunit organization GO:0043933 339 0.065
response to vitamin GO:0033273 131 0.060
reproductive process GO:0022414 372 0.059
response to bacterium GO:0009617 200 0.059
tissue development GO:0009888 252 0.053
positive regulation of cellular component organization GO:0051130 200 0.051
cell migration GO:0016477 197 0.049
anion transport GO:0006820 178 0.047
regulation of cell projection organization GO:0031344 175 0.047
response to other organism GO:0051707 220 0.046
programmed cell death GO:0012501 392 0.044
regulation of molecular function GO:0065009 398 0.044
transmembrane transport GO:0055085 412 0.043
cellular component assembly GO:0022607 360 0.042
protein localization GO:0008104 191 0.042
cell projection organization GO:0030030 302 0.042
single organism biosynthetic process GO:0044711 342 0.042
carboxylic acid transport GO:0046942 115 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
response to corticosteroid GO:0031960 235 0.041
regulation of programmed cell death GO:0043067 341 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
regulation of ion transport GO:0043269 245 0.040
cell motility GO:0048870 202 0.039
oxoacid metabolic process GO:0043436 290 0.039
cellular amine metabolic process GO:0044106 38 0.039
intracellular signal transduction GO:0035556 314 0.038
regulation of locomotion GO:0040012 148 0.038
positive regulation of cell proliferation GO:0008284 249 0.037
multi organism reproductive process GO:0044703 262 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
organic acid transport GO:0015849 116 0.036
positive regulation of cell projection organization GO:0031346 111 0.035
response to estrogen GO:0043627 232 0.035
organic anion transport GO:0015711 132 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
regulation of apoptotic process GO:0042981 335 0.034
amine metabolic process GO:0009308 38 0.034
rna biosynthetic process GO:0032774 380 0.034
regulation of system process GO:0044057 208 0.034
protein phosphorylation GO:0006468 345 0.034
cellular component movement GO:0006928 248 0.034
regulation of signal transduction GO:0009966 318 0.034
reproductive system development GO:0061458 128 0.033
cellular component biogenesis GO:0044085 368 0.033
reproduction GO:0000003 245 0.033
organic substance catabolic process GO:1901575 316 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
organic acid metabolic process GO:0006082 292 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
negative regulation of cellular component organization GO:0051129 83 0.032
neuron development GO:0048666 286 0.032
small molecule biosynthetic process GO:0044283 124 0.031
anatomical structure morphogenesis GO:0009653 298 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
response to glucocorticoid GO:0051384 223 0.030
response to external biotic stimulus GO:0043207 221 0.030
cellular ketone metabolic process GO:0042180 51 0.030
carboxylic acid metabolic process GO:0019752 289 0.029
macromolecule localization GO:0033036 252 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
chemical homeostasis GO:0048878 292 0.029
organelle organization GO:0006996 266 0.028
multicellular organism reproduction GO:0032504 233 0.028
response to acid chemical GO:0001101 222 0.028
defense response GO:0006952 194 0.028
single organism reproductive process GO:0044702 297 0.028
sodium ion transport GO:0006814 82 0.028
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
wound healing GO:0042060 122 0.027
neuron differentiation GO:0030182 368 0.027
protein complex subunit organization GO:0071822 302 0.027
response to decreased oxygen levels GO:0036293 237 0.027
response to estradiol GO:0032355 164 0.027
positive regulation of gene expression GO:0010628 244 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
mesoderm development GO:0007498 2 0.026
apoptotic process GO:0006915 381 0.026
regulation of proteasomal protein catabolic process GO:0061136 4 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
regulation of cell differentiation GO:0045595 320 0.026
positive regulation of signaling GO:0023056 270 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
gastrulation GO:0007369 2 0.025
transcription dna templated GO:0006351 377 0.025
ion transmembrane transport GO:0034220 365 0.025
developmental process involved in reproduction GO:0003006 159 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
positive regulation of molecular function GO:0044093 230 0.024
catabolic process GO:0009056 351 0.024
localization of cell GO:0051674 202 0.024
regulation of rna metabolic process GO:0051252 391 0.024
regulation of neuron differentiation GO:0045664 208 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.023
growth GO:0040007 165 0.023
regeneration GO:0031099 163 0.023
negative regulation of gene expression GO:0010629 199 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
behavior GO:0007610 205 0.023
circulatory system process GO:0003013 183 0.023
cellular catabolic process GO:0044248 295 0.022
multicellular organism growth GO:0035264 1 0.022
endocytosis GO:0006897 84 0.022
cellular ion homeostasis GO:0006873 184 0.022
regulation of neuron projection development GO:0010975 161 0.022
regulation of protein metabolic process GO:0051246 289 0.022
response to peptide hormone GO:0043434 278 0.022
response to ketone GO:1901654 182 0.022
sex differentiation GO:0007548 113 0.022
lipid metabolic process GO:0006629 283 0.021
rna metabolic process GO:0016070 406 0.021
developmental growth GO:0048589 100 0.021
response to peptide GO:1901652 292 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
single organism organelle organization GO:1902589 180 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
cardiovascular system development GO:0072358 134 0.020
negative regulation of developmental process GO:0051093 125 0.020
metal ion transport GO:0030001 289 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
reproductive structure development GO:0048608 128 0.020
protein oligomerization GO:0051259 191 0.020
positive regulation of cell death GO:0010942 184 0.020
regulation of membrane potential GO:0042391 110 0.020
response to wounding GO:0009611 254 0.020
positive regulation of cell communication GO:0010647 271 0.020
mapk cascade GO:0000165 140 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
cation transport GO:0006812 382 0.019
macromolecular complex assembly GO:0065003 273 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
proteolysis GO:0006508 175 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
response to oxidative stress GO:0006979 186 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
regulation of catalytic activity GO:0050790 304 0.019
response to inorganic substance GO:0010035 377 0.019
central nervous system development GO:0007417 311 0.019
positive regulation of cellular component movement GO:0051272 102 0.019
homeostatic process GO:0042592 331 0.019
renal system development GO:0072001 67 0.019
formation of primary germ layer GO:0001704 1 0.019
lipid transport GO:0006869 61 0.018
sexual reproduction GO:0019953 148 0.018
ion homeostasis GO:0050801 212 0.018
neuron projection development GO:0031175 273 0.018
ras protein signal transduction GO:0007265 29 0.018
brain development GO:0007420 247 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
response to oxygen levels GO:0070482 265 0.018
regulation of cellular component movement GO:0051270 150 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
blood circulation GO:0008015 183 0.018
cell cell signaling GO:0007267 335 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
blood vessel development GO:0001568 69 0.018
secretion GO:0046903 307 0.018
response to metal ion GO:0010038 253 0.018
regulation of phosphorylation GO:0042325 248 0.017
regulation of nervous system development GO:0051960 264 0.017
urogenital system development GO:0001655 78 0.017
kidney development GO:0001822 67 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
protein complex biogenesis GO:0070271 263 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cation homeostasis GO:0055080 195 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
aging GO:0007568 241 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
regulation of cell development GO:0060284 263 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.017
response to hypoxia GO:0001666 231 0.017
cellular response to nitrogen compound GO:1901699 210 0.016
nucleic acid templated transcription GO:0097659 379 0.016
regulation of cell motility GO:2000145 131 0.016
negative regulation of innate immune response GO:0045824 4 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
cellular homeostasis GO:0019725 252 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
regulation of cell migration GO:0030334 128 0.016
regulation of growth GO:0040008 105 0.016
anion transmembrane transport GO:0098656 77 0.016
action potential GO:0001508 54 0.016
intracellular transport GO:0046907 185 0.015
nucleotide catabolic process GO:0009166 139 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
cellular response to stress GO:0033554 269 0.015
positive regulation of nervous system development GO:0051962 178 0.015
response to biotic stimulus GO:0009607 226 0.015
negative regulation of transport GO:0051051 136 0.015
negative regulation of cell death GO:0060548 229 0.015
embryonic pattern specification GO:0009880 1 0.015
regulation of anion transport GO:0044070 43 0.015
oxidation reduction process GO:0055114 304 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
male sex differentiation GO:0046661 64 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
nucleotide metabolic process GO:0009117 279 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
response to lipopolysaccharide GO:0032496 191 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
negative regulation of molecular function GO:0044092 133 0.014
gamete generation GO:0007276 124 0.014
circulatory system development GO:0072359 134 0.014
regulation of cell proliferation GO:0042127 359 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
axon development GO:0061564 96 0.014
response to toxic substance GO:0009636 133 0.014
inflammatory response GO:0006954 150 0.014
regulation of response to stress GO:0080134 126 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
regulation of organelle organization GO:0033043 80 0.014
regulation of blood circulation GO:1903522 110 0.014
cell growth GO:0016049 104 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
regulation of synaptic transmission GO:0050804 141 0.014
cellular component morphogenesis GO:0032989 155 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
aromatic compound catabolic process GO:0019439 168 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
cellular lipid metabolic process GO:0044255 208 0.014
regulation of hydrolase activity GO:0051336 143 0.014
development of primary sexual characteristics GO:0045137 107 0.014
negative regulation of rna metabolic process GO:0051253 123 0.013
synaptic transmission GO:0007268 235 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
positive regulation of cell development GO:0010720 176 0.013
single organism cellular localization GO:1902580 102 0.013
cellular cation homeostasis GO:0030003 180 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of catabolic process GO:0009894 113 0.013
gonad development GO:0008406 104 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
lipid localization GO:0010876 62 0.013
biological adhesion GO:0022610 110 0.013
regulation of protein modification process GO:0031399 194 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
steroid biosynthetic process GO:0006694 48 0.013
response to ethanol GO:0045471 162 0.013
actin filament based process GO:0030029 86 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
vascular process in circulatory system GO:0003018 96 0.013
hepaticobiliary system development GO:0061008 90 0.013
regulation of cell growth GO:0001558 85 0.013
secretion by cell GO:0032940 248 0.013
immune system process GO:0002376 204 0.013
positive regulation of transport GO:0051050 245 0.013
organophosphate metabolic process GO:0019637 370 0.012
cellular macromolecule localization GO:0070727 122 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
chromosome segregation GO:0007059 2 0.012
tube development GO:0035295 89 0.012
response to growth factor GO:0070848 189 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
striated muscle tissue development GO:0014706 58 0.012
head development GO:0060322 247 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
purine containing compound metabolic process GO:0072521 253 0.012
axis specification GO:0009798 4 0.012
protein homooligomerization GO:0051260 91 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
muscle structure development GO:0061061 87 0.012
intracellular protein transport GO:0006886 79 0.012
nitrogen compound transport GO:0071705 229 0.012
positive regulation of locomotion GO:0040017 102 0.012
response to amino acid GO:0043200 75 0.012
female gonad development GO:0008585 53 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
positive regulation of developmental process GO:0051094 283 0.012
gland development GO:0048732 155 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
cellular response to growth factor stimulus GO:0071363 162 0.011
regulation of cell cycle GO:0051726 73 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
regulation of tube size GO:0035150 89 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
establishment of protein localization GO:0045184 141 0.011
alcohol metabolic process GO:0006066 77 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
membrane organization GO:0061024 94 0.011
regulation of transcription dna templated GO:0006355 374 0.011
single organism catabolic process GO:0044712 283 0.011
monocarboxylic acid transport GO:0015718 52 0.011
heterocycle catabolic process GO:0046700 167 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cell cycle GO:0007049 101 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
multi multicellular organism process GO:0044706 138 0.011
rhythmic process GO:0048511 156 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
ossification GO:0001503 70 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
chemosensory behavior GO:0007635 2 0.011
cellular protein localization GO:0034613 122 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
response to temperature stimulus GO:0009266 94 0.011
muscle system process GO:0003012 115 0.011
protein complex assembly GO:0006461 263 0.011
regulation of response to external stimulus GO:0032101 106 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
neurological system process GO:0050877 219 0.011
mesoderm morphogenesis GO:0048332 1 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
positive regulation of cell motility GO:2000147 97 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of blood vessel size GO:0050880 89 0.011
positive regulation of ion transport GO:0043270 94 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
purine containing compound catabolic process GO:0072523 138 0.010
negative regulation of cell communication GO:0010648 158 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
gliogenesis GO:0042063 93 0.010
regulation of kinase activity GO:0043549 117 0.010
regulation of transmembrane transport GO:0034762 122 0.010
embryonic appendage morphogenesis GO:0035113 4 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
muscle tissue development GO:0060537 58 0.010
nucleoside metabolic process GO:0009116 179 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
positive regulation of organelle organization GO:0010638 48 0.010
olfactory behavior GO:0042048 2 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010

Phlda2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.011
disease of cellular proliferation DOID:14566 0 0.010