Rattus norvegicus

94 known processes

Cand1

cullin-associated and neddylation-dissociated 1

(Aliases: Tip120A,Tip120)

Cand1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.648
rna biosynthetic process GO:0032774 380 0.440
macromolecular complex subunit organization GO:0043933 339 0.395
mitotic spindle organization GO:0007052 2 0.387
regulation of nucleic acid templated transcription GO:1903506 380 0.344
reproductive process GO:0022414 372 0.338
cytoskeleton organization GO:0007010 111 0.337
spindle organization GO:0007051 2 0.325
cell morphogenesis GO:0000902 142 0.283
organelle organization GO:0006996 266 0.262
nucleic acid templated transcription GO:0097659 379 0.260
single organism reproductive process GO:0044702 297 0.257
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.253
dna packaging GO:0006323 4 0.232
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.225
reproduction GO:0000003 245 0.211
cell cycle GO:0007049 101 0.207
organic acid metabolic process GO:0006082 292 0.201
protein complex subunit organization GO:0071822 302 0.195
mrna metabolic process GO:0016071 20 0.195
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.187
regulation of molecular function GO:0065009 398 0.185
regulation of rna metabolic process GO:0051252 391 0.180
negative regulation of metabolic process GO:0009892 331 0.177
ubiquitin dependent protein catabolic process GO:0006511 14 0.174
apoptotic process GO:0006915 381 0.169
regulation of rna biosynthetic process GO:2001141 381 0.165
regulation of cellular component organization GO:0051128 368 0.164
response to oxygen levels GO:0070482 265 0.163
transcription dna templated GO:0006351 377 0.157
chromatin assembly or disassembly GO:0006333 1 0.143
cellular component assembly GO:0022607 360 0.143
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.139
negative regulation of cellular metabolic process GO:0031324 281 0.136
alternative mrna splicing via spliceosome GO:0000380 4 0.130
vesicle mediated transport GO:0016192 181 0.127
neuron projection development GO:0031175 273 0.127
negative regulation of rna biosynthetic process GO:1902679 118 0.121
negative regulation of gene expression GO:0010629 199 0.121
anatomical structure morphogenesis GO:0009653 298 0.120
cellular component biogenesis GO:0044085 368 0.111
regulation of cellular localization GO:0060341 263 0.108
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.107
positive regulation of signaling GO:0023056 270 0.101
multi organism reproductive process GO:0044703 262 0.101
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.096
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.095
regulation of transcription dna templated GO:0006355 374 0.095
regulation of hormone secretion GO:0046883 106 0.093
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.092
transcription from rna polymerase ii promoter GO:0006366 252 0.092
locomotion GO:0040011 237 0.092
negative regulation of rna metabolic process GO:0051253 123 0.091
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.090
bmp signaling pathway GO:0030509 4 0.089
response to nutrient GO:0007584 248 0.088
negative regulation of biosynthetic process GO:0009890 168 0.088
macromolecular complex assembly GO:0065003 273 0.087
intracellular transport GO:0046907 185 0.079
protein complex biogenesis GO:0070271 263 0.077
response to extracellular stimulus GO:0009991 380 0.077
oxoacid metabolic process GO:0043436 290 0.077
positive regulation of response to stimulus GO:0048584 285 0.076
cell cycle process GO:0022402 57 0.076
central nervous system development GO:0007417 311 0.075
dendrite development GO:0016358 72 0.075
endocytosis GO:0006897 84 0.073
response to nutrient levels GO:0031667 370 0.073
neuron differentiation GO:0030182 368 0.073
regulation of catalytic activity GO:0050790 304 0.072
regulation of intracellular signal transduction GO:1902531 218 0.069
neuron development GO:0048666 286 0.069
negative regulation of cell death GO:0060548 229 0.068
defense response GO:0006952 194 0.067
cellular response to stress GO:0033554 269 0.067
cellular homeostasis GO:0019725 252 0.067
single organism organelle organization GO:1902589 180 0.066
regulation of phosphate metabolic process GO:0019220 349 0.063
cellular catabolic process GO:0044248 295 0.063
macromolecule catabolic process GO:0009057 58 0.063
nucleosome organization GO:0034728 1 0.062
cellular component morphogenesis GO:0032989 155 0.060
sexual reproduction GO:0019953 148 0.060
regulation of peptide transport GO:0090087 87 0.057
cell morphogenesis involved in differentiation GO:0000904 119 0.057
proteolysis GO:0006508 175 0.057
double strand break repair GO:0006302 1 0.057
positive regulation of gene expression GO:0010628 244 0.056
cellular amino acid metabolic process GO:0006520 107 0.056
regulation of cellular response to stress GO:0080135 49 0.056
negative regulation of transcription dna templated GO:0045892 116 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.054
cell projection organization GO:0030030 302 0.053
regulation of signal transduction GO:0009966 318 0.051
intracellular signal transduction GO:0035556 314 0.051
protein catabolic process GO:0030163 30 0.051
protein complex assembly GO:0006461 263 0.050
cellular protein localization GO:0034613 122 0.049
regulation of apoptotic process GO:0042981 335 0.049
regulation of cellular protein metabolic process GO:0032268 267 0.049
establishment of protein localization GO:0045184 141 0.048
regulation of hormone levels GO:0010817 187 0.047
ossification GO:0001503 70 0.047
organic substance catabolic process GO:1901575 316 0.047
single organism intracellular transport GO:1902582 166 0.046
mrna processing GO:0006397 14 0.046
regulation of phosphorylation GO:0042325 248 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
cellular response to growth factor stimulus GO:0071363 162 0.045
cellular component movement GO:0006928 248 0.044
microtubule based process GO:0007017 36 0.044
developmental process involved in reproduction GO:0003006 159 0.044
sensory organ development GO:0007423 74 0.043
multicellular organismal reproductive process GO:0048609 233 0.043
multi multicellular organism process GO:0044706 138 0.043
response to hypoxia GO:0001666 231 0.042
positive regulation of protein modification process GO:0031401 142 0.041
negative regulation of nucleic acid templated transcription GO:1903507 117 0.041
neuron projection morphogenesis GO:0048812 122 0.041
response to growth factor GO:0070848 189 0.040
embryo development GO:0009790 49 0.040
rna processing GO:0006396 22 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.040
reproductive structure development GO:0048608 128 0.039
enzyme linked receptor protein signaling pathway GO:0007167 116 0.039
modification dependent macromolecule catabolic process GO:0043632 14 0.039
mrna stabilization GO:0048255 2 0.039
cellular macromolecule catabolic process GO:0044265 29 0.038
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.038
chromatin organization GO:0006325 34 0.038
gamete generation GO:0007276 124 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.037
negative regulation of programmed cell death GO:0043069 183 0.037
regulation of programmed cell death GO:0043067 341 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
neurological system process GO:0050877 219 0.036
behavior GO:0007610 205 0.036
catabolic process GO:0009056 351 0.035
transmembrane transport GO:0055085 412 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
regulation of protein modification process GO:0031399 194 0.035
response to inorganic substance GO:0010035 377 0.035
response to decreased oxygen levels GO:0036293 237 0.034
multicellular organism reproduction GO:0032504 233 0.034
response to estrogen GO:0043627 232 0.034
macromolecule localization GO:0033036 252 0.034
negative regulation of signaling GO:0023057 157 0.033
cell part morphogenesis GO:0032990 123 0.033
programmed cell death GO:0012501 392 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.033
homeostatic process GO:0042592 331 0.032
positive regulation of cell communication GO:0010647 271 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
regulation of organelle organization GO:0033043 80 0.031
regulation of protein metabolic process GO:0051246 289 0.031
chromosome segregation GO:0007059 2 0.031
proteasomal protein catabolic process GO:0010498 8 0.030
cell motility GO:0048870 202 0.030
cellular response to organic cyclic compound GO:0071407 202 0.030
signal transduction by phosphorylation GO:0023014 144 0.030
organ morphogenesis GO:0009887 75 0.029
regulation of neurogenesis GO:0050767 247 0.029
learning GO:0007612 33 0.029
peptidyl tyrosine phosphorylation GO:0018108 72 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
regulation of peptide hormone secretion GO:0090276 80 0.029
immune response GO:0006955 104 0.029
cellular response to cytokine stimulus GO:0071345 127 0.029
negative regulation of intracellular signal transduction GO:1902532 38 0.028
mitotic cell cycle GO:0000278 49 0.028
dna metabolic process GO:0006259 96 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
mrna 3 end processing GO:0031124 1 0.028
protein transport GO:0015031 132 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.027
osteoblast differentiation GO:0001649 26 0.027
fertilization GO:0009566 3 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
protein phosphorylation GO:0006468 345 0.026
cytoplasmic transport GO:0016482 115 0.026
secretion GO:0046903 307 0.026
protein localization to organelle GO:0033365 57 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
adult locomotory behavior GO:0008344 4 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
hormone secretion GO:0046879 115 0.025
response to metal ion GO:0010038 253 0.025
head development GO:0060322 247 0.025
positive regulation of neurogenesis GO:0050769 165 0.024
response to other organism GO:0051707 220 0.024
modification dependent protein catabolic process GO:0019941 14 0.024
signal release GO:0023061 145 0.024
cell migration GO:0016477 197 0.024
chromosome localization GO:0050000 1 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
amine metabolic process GO:0009308 38 0.024
axon development GO:0061564 96 0.024
localization of cell GO:0051674 202 0.024
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of gene expression epigenetic GO:0040029 10 0.023
sex differentiation GO:0007548 113 0.023
secretion by cell GO:0032940 248 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
cellular protein catabolic process GO:0044257 19 0.023
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.023
positive regulation of apoptotic process GO:0043065 154 0.022
cell cell signaling GO:0007267 335 0.022
centrosome cycle GO:0007098 1 0.022
negative regulation of cell communication GO:0010648 158 0.022
chemosensory behavior GO:0007635 2 0.022
positive regulation of signal transduction GO:0009967 175 0.022
cognition GO:0050890 92 0.021
mesenchyme development GO:0060485 9 0.021
response to light stimulus GO:0009416 52 0.021
tissue development GO:0009888 252 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
brain development GO:0007420 247 0.021
response to external biotic stimulus GO:0043207 221 0.021
mitotic cell cycle process GO:1903047 35 0.021
wound healing GO:0042060 122 0.021
regulation of intracellular transport GO:0032386 65 0.021
lymphocyte activation involved in immune response GO:0002285 3 0.021
response to transforming growth factor beta GO:0071559 46 0.021
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
cellular macromolecule localization GO:0070727 122 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
rhythmic process GO:0048511 156 0.020
single fertilization GO:0007338 3 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
mitotic nuclear division GO:0007067 15 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
regulation of dendrite morphogenesis GO:0048814 33 0.019
positive regulation of cell death GO:0010942 184 0.019
nitrogen compound transport GO:0071705 229 0.019
protein maturation GO:0051604 68 0.019
purine containing compound metabolic process GO:0072521 253 0.019
learning or memory GO:0007611 90 0.019
response to toxic substance GO:0009636 133 0.019
negative regulation of cell proliferation GO:0008285 119 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.018
positive regulation of transport GO:0051050 245 0.018
actin filament based process GO:0030029 86 0.018
cellular chemical homeostasis GO:0055082 247 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
inflammatory response GO:0006954 150 0.018
protein localization GO:0008104 191 0.018
retinal cell programmed cell death GO:0046666 1 0.018
regulation of nervous system development GO:0051960 264 0.018
negative regulation of developmental process GO:0051093 125 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
signal transduction involved in regulation of gene expression GO:0023019 4 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
blood vessel development GO:0001568 69 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of signal transduction GO:0009968 83 0.017
cell type specific apoptotic process GO:0097285 134 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
organelle assembly GO:0070925 22 0.017
olfactory behavior GO:0042048 2 0.017
chromosome organization GO:0051276 36 0.017
associative learning GO:0008306 19 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.017
positive regulation of cellular component biogenesis GO:0044089 55 0.016
cation homeostasis GO:0055080 195 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
insulin secretion GO:0030073 69 0.016
peptide secretion GO:0002790 86 0.016
sperm egg recognition GO:0035036 1 0.016
peptide transport GO:0015833 97 0.016
toxin transport GO:1901998 3 0.016
cell projection morphogenesis GO:0048858 123 0.016
regulation of cell differentiation GO:0045595 320 0.016
cellular response to dna damage stimulus GO:0006974 19 0.015
negative regulation of circadian rhythm GO:0042754 5 0.015
reproductive system development GO:0061458 128 0.015
eye development GO:0001654 50 0.015
cellular response to hypoxia GO:0071456 51 0.015
organelle fission GO:0048285 25 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
carbohydrate metabolic process GO:0005975 130 0.015
chemotaxis GO:0006935 66 0.015
ion homeostasis GO:0050801 212 0.015
regulation of mrna stability GO:0043488 3 0.015
protein import into nucleus GO:0006606 35 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
transforming growth factor beta3 production GO:0032907 2 0.014
protein homooligomerization GO:0051260 91 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
axis specification GO:0009798 4 0.014
regulation of homeostatic process GO:0032844 101 0.014
regulation of peptide secretion GO:0002791 82 0.014
response to biotic stimulus GO:0009607 226 0.014
eye morphogenesis GO:0048592 4 0.014
positive regulation of bone mineralization GO:0030501 4 0.014
cellular response to external stimulus GO:0071496 118 0.013
cellular response to nutrient levels GO:0031669 60 0.013
positive regulation of molecular function GO:0044093 230 0.013
binding of sperm to zona pellucida GO:0007339 1 0.013
regulation of insulin secretion GO:0050796 65 0.013
leukocyte activation involved in immune response GO:0002366 16 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
response to vitamin GO:0033273 131 0.013
peptide hormone secretion GO:0030072 84 0.013
regulation of cell growth GO:0001558 85 0.013
cellular cation homeostasis GO:0030003 180 0.012
protein oligomerization GO:0051259 191 0.012
regulation of response to stress GO:0080134 126 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 28 0.012
amide transport GO:0042886 105 0.012
hormone transport GO:0009914 121 0.012
response to oxidative stress GO:0006979 186 0.012
nuclear transport GO:0051169 49 0.012
establishment of protein localization to organelle GO:0072594 44 0.012
histone modification GO:0016570 30 0.012
rna stabilization GO:0043489 2 0.012
dna conformation change GO:0071103 10 0.012
response to reactive oxygen species GO:0000302 120 0.012
growth GO:0040007 165 0.012
negative regulation of neuron death GO:1901215 69 0.012
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
gonad development GO:0008406 104 0.011
ncrna processing GO:0034470 3 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of cell development GO:0060284 263 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
chromatin modification GO:0016568 33 0.011
intracellular protein transport GO:0006886 79 0.011
metaphase plate congression GO:0051310 1 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cation transmembrane transport GO:0098655 263 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
rna splicing via transesterification reactions GO:0000375 7 0.011
mapk cascade GO:0000165 140 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
positive regulation of leukocyte degranulation GO:0043302 4 0.010
negative regulation of neuron apoptotic process GO:0043524 45 0.010
cellular protein complex assembly GO:0043623 44 0.010
response to monosaccharide GO:0034284 159 0.010
lipid metabolic process GO:0006629 283 0.010
regulation of cell cycle GO:0051726 73 0.010
single organism behavior GO:0044708 130 0.010
cellular ion homeostasis GO:0006873 184 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010

Cand1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
central nervous system disease DOID:331 0 0.021