Rattus norvegicus

57 known processes

Mgst1

microsomal glutathione S-transferase 1

(Aliases: MGC72699)

Mgst1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutathione metabolic process GO:0006749 15 0.888
Mouse
xenobiotic catabolic process GO:0042178 7 0.827
cellular response to xenobiotic stimulus GO:0071466 19 0.825
peptide metabolic process GO:0006518 32 0.800
Mouse
oxidation reduction process GO:0055114 304 0.799
Human
response to xenobiotic stimulus GO:0009410 23 0.782
response to nutrient levels GO:0031667 370 0.696
response to inorganic substance GO:0010035 377 0.672
Rat
cellular modified amino acid metabolic process GO:0006575 61 0.664
Mouse
cellular response to cell matrix adhesion GO:0071460 5 0.639
cellular amide metabolic process GO:0043603 44 0.621
Mouse
xenobiotic metabolic process GO:0006805 19 0.618
response to herbicide GO:0009635 16 0.575
chlorinated hydrocarbon metabolic process GO:0042196 4 0.574
response to metal ion GO:0010038 253 0.488
Rat
organic acid metabolic process GO:0006082 292 0.478
Mouse Rat
response to acid chemical GO:0001101 222 0.424
Rat
response to glucocorticoid GO:0051384 223 0.401
response to vitamin GO:0033273 131 0.392
glial cell development GO:0021782 19 0.389
cellular catabolic process GO:0044248 295 0.354
oxoacid metabolic process GO:0043436 290 0.346
Mouse Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.329
toxin catabolic process GO:0009407 1 0.315
cellular response to peptide GO:1901653 133 0.306
response to amino acid GO:0043200 75 0.304
carboxylic acid metabolic process GO:0019752 289 0.300
Mouse Rat
response to carbohydrate GO:0009743 183 0.291
cellular response to endogenous stimulus GO:0071495 377 0.288
response to epidermal growth factor GO:0070849 18 0.285
response to estradiol GO:0032355 164 0.276
cellular response to organonitrogen compound GO:0071417 197 0.273
response to zinc ion GO:0010043 39 0.266
response to l ascorbic acid GO:0033591 15 0.257
response to mercury ion GO:0046689 15 0.257
response to transition metal nanoparticle GO:1990267 122 0.255
response to extracellular stimulus GO:0009991 380 0.255
organic substance catabolic process GO:1901575 316 0.254
cellular response to organic cyclic compound GO:0071407 202 0.251
response to toxic substance GO:0009636 133 0.248
catabolic process GO:0009056 351 0.247
response to corticosteroid GO:0031960 235 0.244
monocarboxylic acid metabolic process GO:0032787 152 0.241
Rat
response to peptide GO:1901652 292 0.237
lipid oxidation GO:0034440 30 0.231
organ regeneration GO:0031100 101 0.226
cellular response to corticosteroid stimulus GO:0071384 69 0.217
response to bacterium GO:0009617 200 0.210
cellular response to oxygen containing compound GO:1901701 386 0.205
Human
cellular response to lipid GO:0071396 201 0.205
response to nicotine GO:0035094 51 0.204
cellular response to glucocorticoid stimulus GO:0071385 68 0.200
cellular response to nitrogen compound GO:1901699 210 0.197
response to peptide hormone GO:0043434 278 0.197
cellular response to insulin stimulus GO:0032869 81 0.190
cellular response to epidermal growth factor stimulus GO:0071364 12 0.183
aging GO:0007568 241 0.181
response to insulin GO:0032868 133 0.175
response to growth factor GO:0070848 189 0.169
lipid metabolic process GO:0006629 283 0.163
Rat
single organism catabolic process GO:0044712 283 0.162
cellular response to external stimulus GO:0071496 118 0.159
regeneration GO:0031099 163 0.157
cellular response to hormone stimulus GO:0032870 247 0.153
cellular response to growth factor stimulus GO:0071363 162 0.150
oligodendrocyte development GO:0014003 10 0.145
response to estrogen GO:0043627 232 0.143
cellular lipid metabolic process GO:0044255 208 0.134
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.133
response to alkaloid GO:0043279 132 0.131
glial cell differentiation GO:0010001 65 0.127
gliogenesis GO:0042063 93 0.127
organic acid catabolic process GO:0016054 49 0.121
cellular response to steroid hormone stimulus GO:0071383 93 0.121
retinal metabolic process GO:0042574 3 0.103
cellular response to metal ion GO:0071248 55 0.103
carboxylic acid catabolic process GO:0046395 49 0.102
tissue development GO:0009888 252 0.102
response to lithium ion GO:0010226 28 0.102
response to external biotic stimulus GO:0043207 221 0.099
central nervous system development GO:0007417 311 0.097
sulfur compound metabolic process GO:0006790 70 0.095
Mouse
mesonephros development GO:0001823 14 0.095
monocarboxylic acid catabolic process GO:0072329 28 0.094
response to ethanol GO:0045471 162 0.089
hormone metabolic process GO:0042445 69 0.087
mesonephric epithelium development GO:0072163 14 0.085
halogenated hydrocarbon metabolic process GO:0042197 4 0.079
secondary metabolite catabolic process GO:0090487 1 0.076
ureteric bud development GO:0001657 14 0.075
cellular response to extracellular stimulus GO:0031668 73 0.068
response to vitamin e GO:0033197 24 0.068
response to nutrient GO:0007584 248 0.066
lipid catabolic process GO:0016042 46 0.065
small molecule catabolic process GO:0044282 59 0.061
organic cyclic compound catabolic process GO:1901361 175 0.061
cellular component assembly GO:0022607 360 0.060
protein oligomerization GO:0051259 191 0.058
response to other organism GO:0051707 220 0.057
fatty acid catabolic process GO:0009062 26 0.057
steroid metabolic process GO:0008202 73 0.057
homeostatic process GO:0042592 331 0.056
tube development GO:0035295 89 0.055
carbohydrate metabolic process GO:0005975 130 0.054
cellular amino acid metabolic process GO:0006520 107 0.053
Mouse
response to ketone GO:1901654 182 0.052
cellular hormone metabolic process GO:0034754 49 0.051
macromolecular complex subunit organization GO:0043933 339 0.050
single organism carbohydrate metabolic process GO:0044723 118 0.049
mesonephric tubule development GO:0072164 14 0.049
organophosphate metabolic process GO:0019637 370 0.047
response to genistein GO:0033595 4 0.046
organic hydroxy compound metabolic process GO:1901615 115 0.046
organophosphate biosynthetic process GO:0090407 143 0.046
single organism biosynthetic process GO:0044711 342 0.046
Rat
anatomical structure homeostasis GO:0060249 29 0.046
response to monosaccharide GO:0034284 159 0.045
programmed cell death GO:0012501 392 0.045
response to cadmium ion GO:0046686 35 0.045
small molecule biosynthetic process GO:0044283 124 0.045
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.045
regulation of apoptotic process GO:0042981 335 0.044
multicellular organismal homeostasis GO:0048871 49 0.044
positive regulation of cell communication GO:0010647 271 0.041
metal ion homeostasis GO:0055065 186 0.041
kidney epithelium development GO:0072073 19 0.041
cellular response to stress GO:0033554 269 0.041
Human
organic acid biosynthetic process GO:0016053 83 0.041
Rat
negative regulation of apoptotic process GO:0043066 181 0.039
regulation of signal transduction GO:0009966 318 0.039
cation transport GO:0006812 382 0.037
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.037
protein complex subunit organization GO:0071822 302 0.037
chemical homeostasis GO:0048878 292 0.036
alpha amino acid metabolic process GO:1901605 71 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
renal system development GO:0072001 67 0.034
gland development GO:0048732 155 0.034
macromolecular complex assembly GO:0065003 273 0.034
response to lead ion GO:0010288 33 0.033
anion transport GO:0006820 178 0.033
multi organism reproductive process GO:0044703 262 0.033
cellular component biogenesis GO:0044085 368 0.032
cellular lipid catabolic process GO:0044242 37 0.032
cellular response to inorganic substance GO:0071241 65 0.031
cellular ketone metabolic process GO:0042180 51 0.031
urogenital system development GO:0001655 78 0.031
cell projection organization GO:0030030 302 0.031
response to hypoxia GO:0001666 231 0.030
brain development GO:0007420 247 0.030
positive regulation of transport GO:0051050 245 0.029
protein homooligomerization GO:0051260 91 0.029
multicellular organism reproduction GO:0032504 233 0.029
cellular amine metabolic process GO:0044106 38 0.028
response to wounding GO:0009611 254 0.028
response to axon injury GO:0048678 59 0.027
reactive oxygen species metabolic process GO:0072593 37 0.027
protein complex assembly GO:0006461 263 0.027
heterocycle catabolic process GO:0046700 167 0.027
response to molecule of bacterial origin GO:0002237 194 0.026
negative regulation of cell death GO:0060548 229 0.026
regulation of immune system process GO:0002682 123 0.026
secondary metabolic process GO:0019748 15 0.026
regulation of neurogenesis GO:0050767 247 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
liver development GO:0001889 90 0.025
response to decreased oxygen levels GO:0036293 237 0.025
steroid biosynthetic process GO:0006694 48 0.025
heart morphogenesis GO:0003007 3 0.024
negative regulation of metabolic process GO:0009892 331 0.024
lipid biosynthetic process GO:0008610 128 0.024
Rat
androgen metabolic process GO:0008209 14 0.024
regulation of programmed cell death GO:0043067 341 0.024
development of primary sexual characteristics GO:0045137 107 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
single organism behavior GO:0044708 130 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
synaptic transmission GO:0007268 235 0.023
reproduction GO:0000003 245 0.023
dna modification GO:0006304 12 0.023
phenol containing compound metabolic process GO:0018958 30 0.023
amine metabolic process GO:0009308 38 0.022
oligodendrocyte differentiation GO:0048709 32 0.022
response to nitrosative stress GO:0051409 2 0.022
telencephalon development GO:0021537 62 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
protein complex biogenesis GO:0070271 263 0.022
regulation of cell proliferation GO:0042127 359 0.022
multicellular organism growth GO:0035264 1 0.022
intracellular transport GO:0046907 185 0.022
fatty acid oxidation GO:0019395 29 0.022
sexual reproduction GO:0019953 148 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
negative regulation of oxidoreductase activity GO:0051354 4 0.021
positive regulation of developmental process GO:0051094 283 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
metal ion transport GO:0030001 289 0.021
single organism intracellular transport GO:1902582 166 0.021
nucleic acid templated transcription GO:0097659 379 0.021
immune system process GO:0002376 204 0.021
neurological system process GO:0050877 219 0.020
sorbitol metabolic process GO:0006060 1 0.019
neuron differentiation GO:0030182 368 0.019
regulation of cell differentiation GO:0045595 320 0.019
response to lipopolysaccharide GO:0032496 191 0.019
cation homeostasis GO:0055080 195 0.019
protein homotetramerization GO:0051289 25 0.019
cellular chemical homeostasis GO:0055082 247 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
gamete generation GO:0007276 124 0.018
cellular homeostasis GO:0019725 252 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
female pregnancy GO:0007565 122 0.018
lipid modification GO:0030258 52 0.018
reproductive structure development GO:0048608 128 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
regulation of phosphorylation GO:0042325 248 0.018
regulation of lipid biosynthetic process GO:0046890 38 0.018
molting cycle process GO:0022404 2 0.018
fatty acid beta oxidation GO:0006635 22 0.017
phenylpropanoid catabolic process GO:0046271 3 0.017
regulation of cell development GO:0060284 263 0.017
mapk cascade GO:0000165 140 0.017
amp metabolic process GO:0046033 8 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of protein metabolic process GO:0051246 289 0.017
regulation of multicellular organismal development GO:2000026 376 0.016
transmembrane transport GO:0055085 412 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
negative regulation of cell communication GO:0010648 158 0.016
cofactor metabolic process GO:0051186 95 0.016
gonad development GO:0008406 104 0.016
apoptotic process GO:0006915 381 0.016
response to potassium ion GO:0035864 9 0.016
positive regulation of nervous system development GO:0051962 178 0.016
developmental process involved in reproduction GO:0003006 159 0.016
response to reactive oxygen species GO:0000302 120 0.016
protein phosphorylation GO:0006468 345 0.015
monosaccharide metabolic process GO:0005996 61 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of signaling GO:0023056 270 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
ion homeostasis GO:0050801 212 0.015
alcohol metabolic process GO:0006066 77 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
protein refolding GO:0042026 3 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.015
ion transmembrane transport GO:0034220 365 0.015
response to purine containing compound GO:0014074 126 0.015
intracellular signal transduction GO:0035556 314 0.015
axis specification GO:0009798 4 0.015
negative regulation of stress activated mapk cascade GO:0032873 4 0.015
positive regulation of signal transduction GO:0009967 175 0.015
neuron projection development GO:0031175 273 0.015
secretion GO:0046903 307 0.015
regulation of map kinase activity GO:0043405 53 0.015
response to organophosphorus GO:0046683 102 0.014
epithelium development GO:0060429 96 0.014
hepaticobiliary system development GO:0061008 90 0.014
nonribosomal peptide biosynthetic process GO:0019184 3 0.014
behavior GO:0007610 205 0.014
response to aluminum ion GO:0010044 10 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of nervous system development GO:0051960 264 0.014
negative regulation of gene expression GO:0010629 199 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
peptide biosynthetic process GO:0043043 3 0.014
cell type specific apoptotic process GO:0097285 134 0.014
neuron development GO:0048666 286 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
mechanoreceptor differentiation GO:0042490 2 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
single organism reproductive process GO:0044702 297 0.014
amino acid betaine metabolic process GO:0006577 3 0.014
response to glucose GO:0009749 136 0.013
regulation of hormone levels GO:0010817 187 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of ion transport GO:0043269 245 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
organic hydroxy compound transport GO:0015850 77 0.013
sex differentiation GO:0007548 113 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
chemosensory behavior GO:0007635 2 0.013
leydig cell differentiation GO:0033327 8 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of rna metabolic process GO:0051252 391 0.013
cytokine production GO:0001816 61 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
rna metabolic process GO:0016070 406 0.013
organelle organization GO:0006996 266 0.013
kidney development GO:0001822 67 0.013
insecticide metabolic process GO:0017143 4 0.013
positive regulation of immune system process GO:0002684 90 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
regulation of transcription dna templated GO:0006355 374 0.012
regulation of neuron death GO:1901214 115 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of catalytic activity GO:0050790 304 0.012
head development GO:0060322 247 0.012
cellular component movement GO:0006928 248 0.012
organic anion transport GO:0015711 132 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
immune response GO:0006955 104 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
glutamine family amino acid biosynthetic process GO:0009084 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
response to starvation GO:0042594 59 0.012
growth GO:0040007 165 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of kinase activity GO:0043549 117 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
response to hexose GO:0009746 144 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.012
alpha amino acid biosynthetic process GO:1901607 23 0.012
cellular response to superoxide GO:0071451 6 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
benzene containing compound metabolic process GO:0042537 22 0.012
deoxyribonucleoside triphosphate metabolic process GO:0009200 6 0.012
erk1 and erk2 cascade GO:0070371 48 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
nitrogen compound transport GO:0071705 229 0.011
reproductive process GO:0022414 372 0.011
regulation of neuron projection development GO:0010975 161 0.011
rna biosynthetic process GO:0032774 380 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
hexose metabolic process GO:0019318 58 0.011
response to corticosterone GO:0051412 40 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
male gamete generation GO:0048232 99 0.011
regulation of response to stress GO:0080134 126 0.011
deoxyribose phosphate metabolic process GO:0019692 9 0.011
calcium ion transport GO:0006816 131 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
regulation of molecular function GO:0065009 398 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
catecholamine metabolic process GO:0006584 19 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
nucleotide metabolic process GO:0009117 279 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
regulation of catabolic process GO:0009894 113 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
response to catechin GO:1902168 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
alditol metabolic process GO:0019400 4 0.011
action potential GO:0001508 54 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
protein tetramerization GO:0051262 38 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
macromolecule localization GO:0033036 252 0.010
positive regulation of protein modification process GO:0031401 142 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
response to osmotic stress GO:0006970 42 0.010
circulatory system process GO:0003013 183 0.010
purine containing compound metabolic process GO:0072521 253 0.010
negative regulation of secretion GO:0051048 82 0.010
inflammatory response GO:0006954 150 0.010
Rat
negative regulation of cell proliferation GO:0008285 119 0.010
cytoplasmic transport GO:0016482 115 0.010
2 deoxyribonucleotide metabolic process GO:0009394 9 0.010
regulation of protein modification process GO:0031399 194 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
olfactory behavior GO:0042048 2 0.010
auditory receptor cell differentiation GO:0042491 2 0.010
regulation of neuron differentiation GO:0045664 208 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
axon development GO:0061564 96 0.010
regulation of immune response GO:0050776 55 0.010

Mgst1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
inherited metabolic disorder DOID:655 0 0.048
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020