Rattus norvegicus

39 known processes

Timp4

tissue inhibitor of metalloproteinase 4

Timp4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.094
positive regulation of cellular biosynthetic process GO:0031328 295 0.085
Rat
regulation of rna biosynthetic process GO:2001141 381 0.076
single organism biosynthetic process GO:0044711 342 0.075
Rat
oxoacid metabolic process GO:0043436 290 0.072
organic acid metabolic process GO:0006082 292 0.064
regulation of molecular function GO:0065009 398 0.063
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.056
transcription dna templated GO:0006351 377 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
Rat
carboxylic acid metabolic process GO:0019752 289 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
Rat
macromolecule localization GO:0033036 252 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.041
Rat
rna metabolic process GO:0016070 406 0.041
positive regulation of rna biosynthetic process GO:1902680 197 0.040
organophosphate metabolic process GO:0019637 370 0.040
Rat
intracellular signal transduction GO:0035556 314 0.039
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
Rat
rna biosynthetic process GO:0032774 380 0.036
transcription from rna polymerase ii promoter GO:0006366 252 0.036
regulation of cell differentiation GO:0045595 320 0.036
Rat
negative regulation of signaling GO:0023057 157 0.033
Rat
positive regulation of rna metabolic process GO:0051254 203 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
Rat
nucleotide metabolic process GO:0009117 279 0.031
Rat
fatty acid metabolic process GO:0006631 99 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
Rat
positive regulation of gene expression GO:0010628 244 0.030
negative regulation of metabolic process GO:0009892 331 0.030
Rat
ras protein signal transduction GO:0007265 29 0.030
Rat
positive regulation of cell proliferation GO:0008284 249 0.030
aging GO:0007568 241 0.029
Rat
positive regulation of biosynthetic process GO:0009891 319 0.028
Rat
establishment of tissue polarity GO:0007164 2 0.028
multicellular organism reproduction GO:0032504 233 0.028
positive regulation of transcription dna templated GO:0045893 197 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
response to other organism GO:0051707 220 0.026
cellular catabolic process GO:0044248 295 0.026
nucleic acid templated transcription GO:0097659 379 0.026
multi organism reproductive process GO:0044703 262 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
Rat
regulation of hydrolase activity GO:0051336 143 0.025
Rat
positive regulation of cell communication GO:0010647 271 0.025
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regeneration GO:0031099 163 0.025
Rat
cellular amine metabolic process GO:0044106 38 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.025
regulation of transcription dna templated GO:0006355 374 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
regulation of rna metabolic process GO:0051252 391 0.024
reproductive process GO:0022414 372 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Rat
positive regulation of molecular function GO:0044093 230 0.024
Rat
cellular response to endogenous stimulus GO:0071495 377 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
Rat
response to estradiol GO:0032355 164 0.023
cellular response to stress GO:0033554 269 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
neuron differentiation GO:0030182 368 0.022
Rat
programmed cell death GO:0012501 392 0.022
Rat
response to nutrient levels GO:0031667 370 0.022
Rat
single organism organelle organization GO:1902589 180 0.022
response to extracellular stimulus GO:0009991 380 0.022
Rat
lipid metabolic process GO:0006629 283 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
cellular homeostasis GO:0019725 252 0.021
organic substance catabolic process GO:1901575 316 0.021
cardiac conduction GO:0061337 2 0.021
response to estrogen GO:0043627 232 0.021
Rat
single organism catabolic process GO:0044712 283 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
Rat
protein phosphorylation GO:0006468 345 0.021
metal ion homeostasis GO:0055065 186 0.020
catabolic process GO:0009056 351 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
chemical homeostasis GO:0048878 292 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
Rat
cation transport GO:0006812 382 0.020
negative regulation of gene expression GO:0010629 199 0.020
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of catalytic activity GO:0050790 304 0.020
Rat
negative regulation of cell communication GO:0010648 158 0.019
Rat
amine metabolic process GO:0009308 38 0.019
peptide secretion GO:0002790 86 0.019
regulation of cell proliferation GO:0042127 359 0.019
Rat
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of transport GO:0051051 136 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of cell development GO:0060284 263 0.018
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
regulation of synaptic transmission GO:0050804 141 0.018
transmembrane transport GO:0055085 412 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
oxidation reduction process GO:0055114 304 0.018
regulation of phosphorylation GO:0042325 248 0.018
Rat
cellular component biogenesis GO:0044085 368 0.017
single organism behavior GO:0044708 130 0.017
response to peptide GO:1901652 292 0.017
peptide hormone secretion GO:0030072 84 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
Rat
response to ketone GO:1901654 182 0.017
reproduction GO:0000003 245 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
Rat
positive regulation of phosphorylation GO:0042327 177 0.017
Rat
purine containing compound metabolic process GO:0072521 253 0.017
Rat
inorganic ion transmembrane transport GO:0098660 229 0.017
neuron projection development GO:0031175 273 0.017
lipid storage GO:0019915 1 0.017
cellular lipid metabolic process GO:0044255 208 0.017
central nervous system development GO:0007417 311 0.017
small gtpase mediated signal transduction GO:0007264 36 0.016
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to peptide hormone GO:0043434 278 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
response to carbohydrate GO:0009743 183 0.016
ion homeostasis GO:0050801 212 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
regulation of apoptotic process GO:0042981 335 0.016
Rat
cellular response to oxygen containing compound GO:1901701 386 0.016
response to nutrient GO:0007584 248 0.016
Rat
negative regulation of molecular function GO:0044092 133 0.016
Rat
protein complex assembly GO:0006461 263 0.016
regulation of membrane potential GO:0042391 110 0.015
secretion GO:0046903 307 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
heterocycle catabolic process GO:0046700 167 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
positive regulation of secretion GO:0051047 140 0.015
positive regulation of nervous system development GO:0051962 178 0.015
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
carboxylic acid catabolic process GO:0046395 49 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
response to glucocorticoid GO:0051384 223 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
Rat
cellular component assembly GO:0022607 360 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.014
ion transmembrane transport GO:0034220 365 0.014
protein localization GO:0008104 191 0.014
response to bacterium GO:0009617 200 0.014
neurological system process GO:0050877 219 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
Rat
cellular response to hormone stimulus GO:0032870 247 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
regulation of programmed cell death GO:0043067 341 0.014
Rat
regulation of nervous system development GO:0051960 264 0.014
Rat
regulation of neurogenesis GO:0050767 247 0.014
Rat
axis specification GO:0009798 4 0.014
multicellular organismal signaling GO:0035637 44 0.014
multi multicellular organism process GO:0044706 138 0.014
wound healing GO:0042060 122 0.014
Rat
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of cellular component organization GO:0051128 368 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
Rat
transmission of nerve impulse GO:0019226 42 0.014
metal ion transport GO:0030001 289 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
protein complex biogenesis GO:0070271 263 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
sexual reproduction GO:0019953 148 0.013
cellular ion homeostasis GO:0006873 184 0.013
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.013
regulation of growth GO:0040008 105 0.013
circulatory system process GO:0003013 183 0.013
rhythmic process GO:0048511 156 0.013
response to wounding GO:0009611 254 0.013
Rat
regulation of anatomical structure size GO:0090066 135 0.013
homeostatic process GO:0042592 331 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of signaling GO:0023056 270 0.013
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
Rat
regulation of protein modification process GO:0031399 194 0.012
regulation of blood circulation GO:1903522 110 0.012
nucleoside metabolic process GO:0009116 179 0.012
neuronal action potential GO:0019228 35 0.012
cytoplasmic transport GO:0016482 115 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
anterior posterior pattern specification GO:0009952 1 0.012
peptidyl amino acid modification GO:0018193 126 0.012
cell projection organization GO:0030030 302 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
Rat
cellular chemical homeostasis GO:0055082 247 0.012
maintenance of location GO:0051235 17 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
membrane repolarization GO:0086009 1 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
regulation of peptide secretion GO:0002791 82 0.012
macromolecular complex assembly GO:0065003 273 0.011
regulation of cellular component movement GO:0051270 150 0.011
male gamete generation GO:0048232 99 0.011
gamete generation GO:0007276 124 0.011
female pregnancy GO:0007565 122 0.011
cell communication involved in cardiac conduction GO:0086065 2 0.011
regulation of ion transport GO:0043269 245 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
action potential GO:0001508 54 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
protein oligomerization GO:0051259 191 0.011
positive regulation of cell development GO:0010720 176 0.011
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
Rat
carbohydrate metabolic process GO:0005975 130 0.011
response to fatty acid GO:0070542 65 0.011
bone development GO:0060348 25 0.011
myelination GO:0042552 39 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
protein complex subunit organization GO:0071822 302 0.011
hormone secretion GO:0046879 115 0.011
regulation of neuron differentiation GO:0045664 208 0.011
Rat
regulation of protein metabolic process GO:0051246 289 0.011
Rat
nucleoside catabolic process GO:0009164 126 0.011
organophosphate catabolic process GO:0046434 148 0.011
response to acid chemical GO:0001101 222 0.011
Rat
organic acid catabolic process GO:0016054 49 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cell cell signaling GO:0007267 335 0.011
response to vitamin GO:0033273 131 0.011
Rat
skeletal system development GO:0001501 41 0.011
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.011
negative regulation of developmental process GO:0051093 125 0.011
regulation of cell growth GO:0001558 85 0.011
response to inorganic substance GO:0010035 377 0.011
spermatogenesis GO:0007283 99 0.011
negative regulation of signal transduction GO:0009968 83 0.010
Rat
negative regulation of catalytic activity GO:0043086 103 0.010
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.010
response to monosaccharide GO:0034284 159 0.010
regulation of system process GO:0044057 208 0.010
positive regulation of protein modification process GO:0031401 142 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
Rat
negative regulation of cell death GO:0060548 229 0.010
Rat
cellular macromolecule localization GO:0070727 122 0.010
embryonic pattern specification GO:0009880 1 0.010

Timp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org