Rattus norvegicus

0 known processes

Txnrd3

thioredoxin reductase 3

Txnrd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.059
macromolecular complex subunit organization GO:0043933 339 0.055
negative regulation of cellular metabolic process GO:0031324 281 0.051
regulation of secretion GO:0051046 224 0.050
response to inorganic substance GO:0010035 377 0.048
oxoacid metabolic process GO:0043436 290 0.048
intracellular signal transduction GO:0035556 314 0.046
negative regulation of metabolic process GO:0009892 331 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.043
macromolecular complex assembly GO:0065003 273 0.041
neuron differentiation GO:0030182 368 0.040
transmembrane transport GO:0055085 412 0.040
organic acid metabolic process GO:0006082 292 0.039
neuron development GO:0048666 286 0.039
secretion GO:0046903 307 0.037
cellular component biogenesis GO:0044085 368 0.034
cellular ketone metabolic process GO:0042180 51 0.033
protein complex biogenesis GO:0070271 263 0.033
cellular amine metabolic process GO:0044106 38 0.033
cation transport GO:0006812 382 0.032
intracellular transport GO:0046907 185 0.032
protein complex subunit organization GO:0071822 302 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
reproductive process GO:0022414 372 0.030
cation transmembrane transport GO:0098655 263 0.029
lipid metabolic process GO:0006629 283 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
cell projection organization GO:0030030 302 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
catabolic process GO:0009056 351 0.028
amine metabolic process GO:0009308 38 0.028
regulation of cell proliferation GO:0042127 359 0.028
organic hydroxy compound metabolic process GO:1901615 115 0.027
neuron projection development GO:0031175 273 0.027
chemical homeostasis GO:0048878 292 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
protein complex assembly GO:0006461 263 0.026
cellular catabolic process GO:0044248 295 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
response to nutrient levels GO:0031667 370 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.025
positive regulation of cell communication GO:0010647 271 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
protein oligomerization GO:0051259 191 0.024
transcription dna templated GO:0006351 377 0.024
regulation of phosphate metabolic process GO:0019220 349 0.023
organophosphate metabolic process GO:0019637 370 0.023
behavior GO:0007610 205 0.023
cellular component assembly GO:0022607 360 0.023
nitrogen compound transport GO:0071705 229 0.022
central nervous system development GO:0007417 311 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
action potential GO:0001508 54 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
cell cell signaling GO:0007267 335 0.021
rna biosynthetic process GO:0032774 380 0.021
oxidation reduction process GO:0055114 304 0.021
regulation of transcription dna templated GO:0006355 374 0.021
regulation of rna metabolic process GO:0051252 391 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of programmed cell death GO:0043067 341 0.021
response to metal ion GO:0010038 253 0.021
single organism intracellular transport GO:1902582 166 0.021
programmed cell death GO:0012501 392 0.021
ion homeostasis GO:0050801 212 0.021
response to extracellular stimulus GO:0009991 380 0.021
secretion by cell GO:0032940 248 0.020
cellular lipid metabolic process GO:0044255 208 0.020
response to acid chemical GO:0001101 222 0.020
regulation of hormone levels GO:0010817 187 0.020
cellular response to stress GO:0033554 269 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
reproductive structure development GO:0048608 128 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
rna metabolic process GO:0016070 406 0.019
organic substance catabolic process GO:1901575 316 0.019
regulation of protein metabolic process GO:0051246 289 0.019
cellular component morphogenesis GO:0032989 155 0.019
regulation of cellular localization GO:0060341 263 0.019
development of primary sexual characteristics GO:0045137 107 0.019
organelle organization GO:0006996 266 0.019
negative regulation of cell communication GO:0010648 158 0.018
cell morphogenesis GO:0000902 142 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
response to oxygen levels GO:0070482 265 0.018
nucleic acid templated transcription GO:0097659 379 0.018
cellular response to lipid GO:0071396 201 0.018
regulation of secretion by cell GO:1903530 208 0.018
single organism catabolic process GO:0044712 283 0.018
positive regulation of signaling GO:0023056 270 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
transmission of nerve impulse GO:0019226 42 0.018
response to growth factor GO:0070848 189 0.018
cell part morphogenesis GO:0032990 123 0.018
response to decreased oxygen levels GO:0036293 237 0.018
response to ethanol GO:0045471 162 0.018
negative regulation of gene expression GO:0010629 199 0.018
regeneration GO:0031099 163 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
single organism biosynthetic process GO:0044711 342 0.017
tissue development GO:0009888 252 0.017
hormone transport GO:0009914 121 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
small molecule biosynthetic process GO:0044283 124 0.017
regulation of apoptotic process GO:0042981 335 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
neuron projection morphogenesis GO:0048812 122 0.017
anion transport GO:0006820 178 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
head development GO:0060322 247 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to peptide GO:1901652 292 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
macromolecule localization GO:0033036 252 0.016
cellular protein localization GO:0034613 122 0.016
brain development GO:0007420 247 0.016
ion transmembrane transport GO:0034220 365 0.016
response to peptide hormone GO:0043434 278 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
organic anion transport GO:0015711 132 0.016
regulation of homeostatic process GO:0032844 101 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
metal ion homeostasis GO:0055065 186 0.016
neurological system process GO:0050877 219 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
apoptotic process GO:0006915 381 0.016
heart morphogenesis GO:0003007 3 0.015
response to nutrient GO:0007584 248 0.015
regulation of system process GO:0044057 208 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of ion transport GO:0043269 245 0.015
single organism reproductive process GO:0044702 297 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of membrane potential GO:0042391 110 0.015
positive regulation of gene expression GO:0010628 244 0.015
signal release GO:0023061 145 0.014
axonogenesis GO:0007409 71 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
ras protein signal transduction GO:0007265 29 0.014
homeostatic process GO:0042592 331 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
response to cytokine GO:0034097 215 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
response to wounding GO:0009611 254 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
alcohol metabolic process GO:0006066 77 0.014
positive regulation of cell development GO:0010720 176 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
response to vitamin GO:0033273 131 0.014
carboxylic acid transport GO:0046942 115 0.014
sex differentiation GO:0007548 113 0.013
cell growth GO:0016049 104 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
metal ion transport GO:0030001 289 0.013
response to glucocorticoid GO:0051384 223 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
gland development GO:0048732 155 0.013
regulation of hydrolase activity GO:0051336 143 0.013
cellular homeostasis GO:0019725 252 0.013
response to organophosphorus GO:0046683 102 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
negative regulation of molecular function GO:0044092 133 0.013
immune system process GO:0002376 204 0.013
cellular cation homeostasis GO:0030003 180 0.013
response to ketone GO:1901654 182 0.013
aging GO:0007568 241 0.013
organic acid transport GO:0015849 116 0.013
axis specification GO:0009798 4 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
cation homeostasis GO:0055080 195 0.013
multi organism reproductive process GO:0044703 262 0.013
regulation of signal transduction GO:0009966 318 0.013
single organism organelle organization GO:1902589 180 0.013
peptide transport GO:0015833 97 0.013
positive regulation of developmental process GO:0051094 283 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of mapk cascade GO:0043408 116 0.012
regulation of cell growth GO:0001558 85 0.012
gastrulation GO:0007369 2 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
amide transport GO:0042886 105 0.012
male sex differentiation GO:0046661 64 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of neuron projection development GO:0010975 161 0.012
reproductive system development GO:0061458 128 0.012
neuronal action potential GO:0019228 35 0.012
positive regulation of nervous system development GO:0051962 178 0.012
hepaticobiliary system development GO:0061008 90 0.012
hormone secretion GO:0046879 115 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
positive regulation of molecular function GO:0044093 230 0.011
protein localization GO:0008104 191 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of phosphorylation GO:0042325 248 0.011
nucleotide metabolic process GO:0009117 279 0.011
gliogenesis GO:0042063 93 0.011
response to camp GO:0051591 91 0.011
negative regulation of signaling GO:0023057 157 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
response to reactive oxygen species GO:0000302 120 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
gonad development GO:0008406 104 0.011
lipid storage GO:0019915 1 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
gamete generation GO:0007276 124 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
response to purine containing compound GO:0014074 126 0.011
protein phosphorylation GO:0006468 345 0.011
positive regulation of signal transduction GO:0009967 175 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
multicellular organism reproduction GO:0032504 233 0.011
protein transport GO:0015031 132 0.011
cardiovascular system development GO:0072358 134 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
regulation of hormone secretion GO:0046883 106 0.011
heterocycle catabolic process GO:0046700 167 0.011
rhythmic process GO:0048511 156 0.011
liver development GO:0001889 90 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cellular chemical homeostasis GO:0055082 247 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
proteolysis GO:0006508 175 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
mapk cascade GO:0000165 140 0.011
cellular ion homeostasis GO:0006873 184 0.011
cell projection morphogenesis GO:0048858 123 0.011
positive regulation of hydrolase activity GO:0051345 86 0.010
aromatic compound catabolic process GO:0019439 168 0.010
peptide hormone secretion GO:0030072 84 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
regulation of neurogenesis GO:0050767 247 0.010
nucleoside metabolic process GO:0009116 179 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of catalytic activity GO:0050790 304 0.010
membrane organization GO:0061024 94 0.010
organophosphate catabolic process GO:0046434 148 0.010
regulation of nervous system development GO:0051960 264 0.010
purine containing compound metabolic process GO:0072521 253 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Txnrd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.018
disease of metabolism DOID:0014667 0 0.013
cardiovascular system disease DOID:1287 0 0.013
central nervous system disease DOID:331 0 0.012
inherited metabolic disorder DOID:655 0 0.012
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011