Rattus norvegicus

29 known processes

Dnase2b

deoxyribonuclease II beta

(Aliases: Dlad,UOX)

Dnase2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to lipopolysaccharide GO:0032496 191 0.246
oxoacid metabolic process GO:0043436 290 0.131
carboxylic acid metabolic process GO:0019752 289 0.127
ion homeostasis GO:0050801 212 0.125
neuron development GO:0048666 286 0.119
organic acid metabolic process GO:0006082 292 0.110
cell migration GO:0016477 197 0.089
urogenital system development GO:0001655 78 0.087
response to molecule of bacterial origin GO:0002237 194 0.085
positive regulation of cell proliferation GO:0008284 249 0.084
gonad development GO:0008406 104 0.082
response to external biotic stimulus GO:0043207 221 0.080
transmembrane transport GO:0055085 412 0.079
regulation of apoptotic process GO:0042981 335 0.074
metal ion homeostasis GO:0055065 186 0.071
response to bacterium GO:0009617 200 0.069
neuron differentiation GO:0030182 368 0.069
renal system development GO:0072001 67 0.069
positive regulation of multicellular organismal process GO:0051240 387 0.065
reproductive system development GO:0061458 128 0.061
g protein coupled receptor signaling pathway GO:0007186 242 0.060
programmed cell death GO:0012501 392 0.059
secretion by cell GO:0032940 248 0.059
anion transport GO:0006820 178 0.059
nitrogen compound transport GO:0071705 229 0.058
response to ketone GO:1901654 182 0.054
kidney development GO:0001822 67 0.053
neuron projection development GO:0031175 273 0.051
response to growth factor GO:0070848 189 0.050
ion transmembrane transport GO:0034220 365 0.050
tissue development GO:0009888 252 0.050
chemical homeostasis GO:0048878 292 0.049
single organism biosynthetic process GO:0044711 342 0.048
single organism reproductive process GO:0044702 297 0.047
response to biotic stimulus GO:0009607 226 0.047
cellular amino acid metabolic process GO:0006520 107 0.046
organic substance catabolic process GO:1901575 316 0.044
homeostatic process GO:0042592 331 0.044
cellular response to endogenous stimulus GO:0071495 377 0.044
apoptotic process GO:0006915 381 0.043
cellular chemical homeostasis GO:0055082 247 0.042
reproduction GO:0000003 245 0.042
regulation of secretion by cell GO:1903530 208 0.041
response to hypoxia GO:0001666 231 0.040
positive regulation of developmental process GO:0051094 283 0.040
nucleic acid templated transcription GO:0097659 379 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
regulation of blood pressure GO:0008217 83 0.039
anatomical structure morphogenesis GO:0009653 298 0.039
catabolic process GO:0009056 351 0.039
regulation of multicellular organismal development GO:2000026 376 0.038
cell motility GO:0048870 202 0.038
regeneration GO:0031099 163 0.037
developmental process involved in reproduction GO:0003006 159 0.037
carboxylic acid biosynthetic process GO:0046394 83 0.036
cellular ketone metabolic process GO:0042180 51 0.035
regulation of metal ion transport GO:0010959 118 0.035
anion transmembrane transport GO:0098656 77 0.035
single organism catabolic process GO:0044712 283 0.034
positive regulation of response to stimulus GO:0048584 285 0.034
protein complex subunit organization GO:0071822 302 0.034
cell projection organization GO:0030030 302 0.033
cation homeostasis GO:0055080 195 0.033
protein homooligomerization GO:0051260 91 0.032
positive regulation of signaling GO:0023056 270 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
metal ion transport GO:0030001 289 0.031
tissue remodeling GO:0048771 40 0.031
positive regulation of cell migration GO:0030335 96 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
sex differentiation GO:0007548 113 0.030
development of primary sexual characteristics GO:0045137 107 0.030
positive regulation of cell communication GO:0010647 271 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
response to peptide hormone GO:0043434 278 0.030
cellular catabolic process GO:0044248 295 0.030
regulation of cell differentiation GO:0045595 320 0.029
amide transport GO:0042886 105 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
cellular response to fluid shear stress GO:0071498 4 0.028
carboxylic acid transport GO:0046942 115 0.028
positive regulation of cell motility GO:2000147 97 0.028
negative regulation of chronic inflammatory response GO:0002677 2 0.028
regulation of programmed cell death GO:0043067 341 0.027
transcription dna templated GO:0006351 377 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
localization of cell GO:0051674 202 0.026
regulation of cellular component organization GO:0051128 368 0.026
intracellular signal transduction GO:0035556 314 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
cell growth GO:0016049 104 0.026
transmission of nerve impulse GO:0019226 42 0.026
regulation of mapk cascade GO:0043408 116 0.026
regulation of protein metabolic process GO:0051246 289 0.026
response to oxygen levels GO:0070482 265 0.025
regulation of ion transport GO:0043269 245 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
response to decreased oxygen levels GO:0036293 237 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
reproductive structure development GO:0048608 128 0.025
response to corticosteroid GO:0031960 235 0.025
macromolecule localization GO:0033036 252 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
regulation of cell proliferation GO:0042127 359 0.024
proteolysis GO:0006508 175 0.024
regulation of cell migration GO:0030334 128 0.024
cellular homeostasis GO:0019725 252 0.024
response to hyperoxia GO:0055093 45 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
regulation of locomotion GO:0040012 148 0.023
regulation of cell motility GO:2000145 131 0.023
nucleotide metabolic process GO:0009117 279 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
cell projection morphogenesis GO:0048858 123 0.022
protein oligomerization GO:0051259 191 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
amine metabolic process GO:0009308 38 0.022
lipid biosynthetic process GO:0008610 128 0.022
negative regulation of cell death GO:0060548 229 0.022
regulation of homeostatic process GO:0032844 101 0.022
central nervous system development GO:0007417 311 0.022
regulation of signal transduction GO:0009966 318 0.021
choline transport GO:0015871 4 0.021
cellular cation homeostasis GO:0030003 180 0.021
aging GO:0007568 241 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
cellular response to molecule of bacterial origin GO:0071219 56 0.021
response to monosaccharide GO:0034284 159 0.021
positive regulation of cell development GO:0010720 176 0.020
cell adhesion GO:0007155 110 0.020
organic hydroxy compound transport GO:0015850 77 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
neuronal action potential GO:0019228 35 0.020
myeloid leukocyte activation GO:0002274 36 0.020
organophosphate metabolic process GO:0019637 370 0.020
positive regulation of nervous system development GO:0051962 178 0.020
cellular amine metabolic process GO:0044106 38 0.019
organic acid biosynthetic process GO:0016053 83 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
organ morphogenesis GO:0009887 75 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
amino acid transport GO:0006865 70 0.019
growth GO:0040007 165 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
negative regulation of long term synaptic potentiation GO:1900272 1 0.019
response to oxidative stress GO:0006979 186 0.019
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.019
calcium ion homeostasis GO:0055074 162 0.019
regulation of cellular localization GO:0060341 263 0.018
regulation of secretion GO:0051046 224 0.018
regulation of phosphorylation GO:0042325 248 0.018
circulatory system development GO:0072359 134 0.018
response to metal ion GO:0010038 253 0.018
organic anion transport GO:0015711 132 0.018
action potential GO:0001508 54 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
cellular component morphogenesis GO:0032989 155 0.018
regulation of organ formation GO:0003156 2 0.018
regulation of immune system process GO:0002682 123 0.017
purine containing compound metabolic process GO:0072521 253 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
negative regulation of secretion GO:0051048 82 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
signal release GO:0023061 145 0.017
positive regulation of transport GO:0051050 245 0.017
glutathione transport GO:0034635 2 0.017
cellular component biogenesis GO:0044085 368 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
response to ethanol GO:0045471 162 0.017
secretion GO:0046903 307 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
small molecule catabolic process GO:0044282 59 0.017
multi organism reproductive process GO:0044703 262 0.016
nucleoside metabolic process GO:0009116 179 0.016
neurological system process GO:0050877 219 0.016
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.016
hormone transport GO:0009914 121 0.016
protein localization GO:0008104 191 0.016
regulation of cell development GO:0060284 263 0.016
peptide transport GO:0015833 97 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
cell part morphogenesis GO:0032990 123 0.016
regulation of nervous system development GO:0051960 264 0.016
protein transport GO:0015031 132 0.016
negative regulation of transport GO:0051051 136 0.016
regulation of anatomical structure size GO:0090066 135 0.016
cellular response to lipid GO:0071396 201 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
small molecule biosynthetic process GO:0044283 124 0.016
angioblast cell migration GO:0035476 1 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
biological adhesion GO:0022610 110 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
muscle cell proliferation GO:0033002 84 0.016
cellular response to stress GO:0033554 269 0.016
cell morphogenesis GO:0000902 142 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
regulation of response to stress GO:0080134 126 0.015
positive regulation of behavior GO:0048520 38 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
cellular response to alcohol GO:0097306 87 0.015
regulation of synaptic transmission GO:0050804 141 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
male sex differentiation GO:0046661 64 0.015
neuron projection morphogenesis GO:0048812 122 0.015
response to glucose GO:0009749 136 0.014
sodium ion transport GO:0006814 82 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
regulation of neurogenesis GO:0050767 247 0.014
regulation of cell growth GO:0001558 85 0.014
response to fatty acid GO:0070542 65 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
protein complex assembly GO:0006461 263 0.014
regulation of protein localization GO:0032880 81 0.014
single organism intracellular transport GO:1902582 166 0.014
rna biosynthetic process GO:0032774 380 0.014
myelination GO:0042552 39 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
response to other organism GO:0051707 220 0.014
synaptic transmission GO:0007268 235 0.014
muscle system process GO:0003012 115 0.014
response to wounding GO:0009611 254 0.014
circulatory system process GO:0003013 183 0.014
ras protein signal transduction GO:0007265 29 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
response to extracellular stimulus GO:0009991 380 0.014
cellular response to growth factor stimulus GO:0071363 162 0.013
autophagic cell death GO:0048102 4 0.013
multicellular organism reproduction GO:0032504 233 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cardiovascular system development GO:0072358 134 0.013
female pregnancy GO:0007565 122 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of transcription dna templated GO:0006355 374 0.013
lipid transport GO:0006869 61 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
neutrophil apoptotic process GO:0001781 4 0.013
positive regulation of gene expression GO:0010628 244 0.013
negative regulation of metabolic process GO:0009892 331 0.013
response to glucocorticoid GO:0051384 223 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
macromolecular complex assembly GO:0065003 273 0.013
ensheathment of neurons GO:0007272 40 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
head development GO:0060322 247 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
epithelial cell differentiation GO:0030855 71 0.013
cation transport GO:0006812 382 0.012
dna metabolic process GO:0006259 96 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
gliogenesis GO:0042063 93 0.012
sodium independent organic anion transport GO:0043252 2 0.012
multicellular organismal signaling GO:0035637 44 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
sexual reproduction GO:0019953 148 0.012
lipid localization GO:0010876 62 0.012
response to radiation GO:0009314 137 0.012
drug transmembrane transport GO:0006855 13 0.012
forebrain development GO:0030900 98 0.012
positive regulation of cell death GO:0010942 184 0.012
vasculature development GO:0001944 70 0.012
regulation of membrane potential GO:0042391 110 0.012
gamete generation GO:0007276 124 0.012
positive regulation of immune system process GO:0002684 90 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
vascular process in circulatory system GO:0003018 96 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
sensory perception of bitter taste GO:0050913 4 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
negative regulation of developmental process GO:0051093 125 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
leukocyte migration GO:0050900 38 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
negative regulation of gene expression GO:0010629 199 0.012
locomotion GO:0040011 237 0.012
regulation of body fluid levels GO:0050878 90 0.012
positive regulation of isotype switching GO:0045830 1 0.011
blood vessel morphogenesis GO:0048514 58 0.011
epithelium development GO:0060429 96 0.011
response to estrogen GO:0043627 232 0.011
t cell chemotaxis GO:0010818 2 0.011
striated muscle tissue development GO:0014706 58 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to estradiol GO:0032355 164 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
protein phosphorylation GO:0006468 345 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
establishment of protein localization GO:0045184 141 0.011
response to carbohydrate GO:0009743 183 0.011
cellular ion homeostasis GO:0006873 184 0.011
regulation of catalytic activity GO:0050790 304 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of glomerulus development GO:0090193 4 0.011
positive regulation of protein metabolic process GO:0051247 178 0.010
rhythmic process GO:0048511 156 0.010
monocarboxylic acid transport GO:0015718 52 0.010
cytoplasmic transport GO:0016482 115 0.010
vesicle mediated transport GO:0016192 181 0.010
positive regulation of blood circulation GO:1903524 65 0.010
hormone secretion GO:0046879 115 0.010
regulation of tube size GO:0035150 89 0.010
response to molecule of fungal origin GO:0002238 3 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
oligopeptide transport GO:0006857 4 0.010
response to electrical stimulus GO:0051602 56 0.010
organ regeneration GO:0031100 101 0.010
sequestering of calcium ion GO:0051208 8 0.010
cellular lipid metabolic process GO:0044255 208 0.010
b cell activation involved in immune response GO:0002312 1 0.010
cofactor metabolic process GO:0051186 95 0.010
regulation of smooth muscle cell migration GO:0014910 36 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
regulation of neuron projection development GO:0010975 161 0.010
second messenger mediated signaling GO:0019932 51 0.010

Dnase2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.050
inherited metabolic disorder DOID:655 0 0.050
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.011