Rattus norvegicus

0 known processes

Siglec1

sialic acid binding Ig-like lectin 1, sialoadhesin

(Aliases: Sn)

Siglec1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
regulation of phosphate metabolic process GO:0019220 349 0.044
regulation of cell differentiation GO:0045595 320 0.042
cell projection organization GO:0030030 302 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
response to extracellular stimulus GO:0009991 380 0.038
organic acid metabolic process GO:0006082 292 0.038
programmed cell death GO:0012501 392 0.037
response to inorganic substance GO:0010035 377 0.036
neuron differentiation GO:0030182 368 0.036
rna metabolic process GO:0016070 406 0.036
regulation of cell proliferation GO:0042127 359 0.035
amine metabolic process GO:0009308 38 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
protein phosphorylation GO:0006468 345 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
rna biosynthetic process GO:0032774 380 0.034
cation transport GO:0006812 382 0.034
cellular amine metabolic process GO:0044106 38 0.034
oxoacid metabolic process GO:0043436 290 0.034
regulation of protein metabolic process GO:0051246 289 0.034
regulation of nervous system development GO:0051960 264 0.034
homeostatic process GO:0042592 331 0.034
regulation of apoptotic process GO:0042981 335 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
apoptotic process GO:0006915 381 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of molecular function GO:0065009 398 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
regulation of rna metabolic process GO:0051252 391 0.031
positive regulation of developmental process GO:0051094 283 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
reproductive process GO:0022414 372 0.031
regulation of transcription dna templated GO:0006355 374 0.031
central nervous system development GO:0007417 311 0.031
transmembrane transport GO:0055085 412 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
chemical homeostasis GO:0048878 292 0.031
neuron development GO:0048666 286 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
regulation of neurogenesis GO:0050767 247 0.030
regulation of programmed cell death GO:0043067 341 0.030
nucleic acid templated transcription GO:0097659 379 0.030
regulation of cellular component organization GO:0051128 368 0.030
cellular component assembly GO:0022607 360 0.029
transcription dna templated GO:0006351 377 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
organophosphate metabolic process GO:0019637 370 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
neuron projection development GO:0031175 273 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
regulation of signal transduction GO:0009966 318 0.029
positive regulation of gene expression GO:0010628 244 0.028
catabolic process GO:0009056 351 0.028
negative regulation of metabolic process GO:0009892 331 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of cell development GO:0060284 263 0.028
cellular component biogenesis GO:0044085 368 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
response to wounding GO:0009611 254 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
immune system process GO:0002376 204 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.027
single organism reproductive process GO:0044702 297 0.027
cellular ketone metabolic process GO:0042180 51 0.027
regulation of catalytic activity GO:0050790 304 0.027
locomotion GO:0040011 237 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
response to oxygen levels GO:0070482 265 0.027
cell cell signaling GO:0007267 335 0.027
secretion GO:0046903 307 0.026
response to biotic stimulus GO:0009607 226 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
cellular response to stress GO:0033554 269 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
cellular component movement GO:0006928 248 0.026
cation homeostasis GO:0055080 195 0.026
ion homeostasis GO:0050801 212 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
metal ion transport GO:0030001 289 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
regulation of phosphorylation GO:0042325 248 0.025
organelle organization GO:0006996 266 0.025
cellular homeostasis GO:0019725 252 0.025
regulation of cellular localization GO:0060341 263 0.025
single organism biosynthetic process GO:0044711 342 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
organic substance catabolic process GO:1901575 316 0.025
protein complex biogenesis GO:0070271 263 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
defense response GO:0006952 194 0.025
cation transmembrane transport GO:0098655 263 0.024
cellular chemical homeostasis GO:0055082 247 0.024
localization of cell GO:0051674 202 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
response to metal ion GO:0010038 253 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
macromolecular complex assembly GO:0065003 273 0.024
positive regulation of molecular function GO:0044093 230 0.024
response to nutrient GO:0007584 248 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
regulation of protein modification process GO:0031399 194 0.023
response to hypoxia GO:0001666 231 0.023
cell motility GO:0048870 202 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
response to decreased oxygen levels GO:0036293 237 0.023
cellular cation homeostasis GO:0030003 180 0.023
response to peptide GO:1901652 292 0.023
ras protein signal transduction GO:0007265 29 0.022
regulation of secretion GO:0051046 224 0.022
tissue development GO:0009888 252 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of neuron differentiation GO:0045664 208 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cell migration GO:0016477 197 0.022
nucleotide metabolic process GO:0009117 279 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
cellular catabolic process GO:0044248 295 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
response to external biotic stimulus GO:0043207 221 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
response to ketone GO:1901654 182 0.021
reproduction GO:0000003 245 0.021
positive regulation of cell death GO:0010942 184 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
single organism catabolic process GO:0044712 283 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
secretion by cell GO:0032940 248 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
response to other organism GO:0051707 220 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
divalent inorganic cation transport GO:0072511 134 0.021
cellular ion homeostasis GO:0006873 184 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
nitrogen compound transport GO:0071705 229 0.020
gland development GO:0048732 155 0.020
cellular response to lipid GO:0071396 201 0.020
regulation of neuron projection development GO:0010975 161 0.020
brain development GO:0007420 247 0.020
response to oxidative stress GO:0006979 186 0.020
metal ion homeostasis GO:0055065 186 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
multi organism reproductive process GO:0044703 262 0.020
response to bacterium GO:0009617 200 0.020
positive regulation of transport GO:0051050 245 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
negative regulation of cell death GO:0060548 229 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
response to cytokine GO:0034097 215 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of cell projection organization GO:0031344 175 0.019
protein complex assembly GO:0006461 263 0.019
regulation of ion transport GO:0043269 245 0.019
response to peptide hormone GO:0043434 278 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to growth factor GO:0070848 189 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
aging GO:0007568 241 0.019
blood circulation GO:0008015 183 0.019
neurological system process GO:0050877 219 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
response to ethanol GO:0045471 162 0.019
intracellular transport GO:0046907 185 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
regulation of system process GO:0044057 208 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
calcium ion transport GO:0006816 131 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
response to lipopolysaccharide GO:0032496 191 0.019
macromolecule localization GO:0033036 252 0.018
head development GO:0060322 247 0.018
positive regulation of signaling GO:0023056 270 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
inflammatory response GO:0006954 150 0.018
single organism organelle organization GO:1902589 180 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
response to estrogen GO:0043627 232 0.018
positive regulation of nervous system development GO:0051962 178 0.018
single organism intracellular transport GO:1902582 166 0.018
response to toxic substance GO:0009636 133 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of locomotion GO:0040012 148 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
response to acid chemical GO:0001101 222 0.018
cellular response to organic cyclic compound GO:0071407 202 0.017
calcium ion homeostasis GO:0055074 162 0.017
negative regulation of developmental process GO:0051093 125 0.017
behavior GO:0007610 205 0.017
divalent metal ion transport GO:0070838 132 0.017
positive regulation of protein modification process GO:0031401 142 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
anion transport GO:0006820 178 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.017
positive regulation of cell development GO:0010720 176 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
protein oligomerization GO:0051259 191 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.016
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
response to estradiol GO:0032355 164 0.016
cardiovascular system development GO:0072358 134 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
circulatory system development GO:0072359 134 0.016
growth GO:0040007 165 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
regulation of hormone levels GO:0010817 187 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
development of primary sexual characteristics GO:0045137 107 0.016
negative regulation of gene expression GO:0010629 199 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
lipid metabolic process GO:0006629 283 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
heart morphogenesis GO:0003007 3 0.016
negative regulation of innate immune response GO:0045824 4 0.016
regeneration GO:0031099 163 0.016
circulatory system process GO:0003013 183 0.016
gonad development GO:0008406 104 0.016
negative regulation of transport GO:0051051 136 0.016
regulation of anatomical structure size GO:0090066 135 0.015
reproductive system development GO:0061458 128 0.015
immune response GO:0006955 104 0.015
nucleoside metabolic process GO:0009116 179 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
proteolysis GO:0006508 175 0.015
synaptic transmission GO:0007268 235 0.015
regulation of hydrolase activity GO:0051336 143 0.015
protein localization GO:0008104 191 0.015
peptidyl amino acid modification GO:0018193 126 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
sex differentiation GO:0007548 113 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
regulation of immune system process GO:0002682 123 0.015
negative regulation of cell communication GO:0010648 158 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
mapk cascade GO:0000165 140 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
limb morphogenesis GO:0035108 4 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
heterocycle catabolic process GO:0046700 167 0.015
aromatic compound catabolic process GO:0019439 168 0.015
cell morphogenesis GO:0000902 142 0.015
cell part morphogenesis GO:0032990 123 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
regulation of neuron death GO:1901214 115 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to carbohydrate GO:0009743 183 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
negative regulation of signaling GO:0023057 157 0.015
regulation of response to stress GO:0080134 126 0.014
response to glucocorticoid GO:0051384 223 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cell projection morphogenesis GO:0048858 123 0.014
salivary gland development GO:0007431 3 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of membrane potential GO:0042391 110 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
rhythmic process GO:0048511 156 0.014
positive regulation of signal transduction GO:0009967 175 0.014
female pregnancy GO:0007565 122 0.014
eye morphogenesis GO:0048592 4 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
anterior posterior pattern specification GO:0009952 1 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular response to external stimulus GO:0071496 118 0.014
hormone transport GO:0009914 121 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
reproductive structure development GO:0048608 128 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
response to hexose GO:0009746 144 0.013
regulation of homeostatic process GO:0032844 101 0.013
spindle organization GO:0007051 2 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
neuron projection morphogenesis GO:0048812 122 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
response to purine containing compound GO:0014074 126 0.013
developmental process involved in reproduction GO:0003006 159 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of cellular component movement GO:0051270 150 0.013
response to vitamin GO:0033273 131 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
response to glucose GO:0009749 136 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
response to reactive oxygen species GO:0000302 120 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
cellular component morphogenesis GO:0032989 155 0.013
response to monosaccharide GO:0034284 159 0.013
negative regulation of molecular function GO:0044092 133 0.013
regulation of response to external stimulus GO:0032101 106 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
cellular lipid metabolic process GO:0044255 208 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
response to alkaloid GO:0043279 132 0.013
response to radiation GO:0009314 137 0.013
axon development GO:0061564 96 0.013
vascular process in circulatory system GO:0003018 96 0.013
sensory perception GO:0007600 101 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
response to corticosteroid GO:0031960 235 0.013
regulation of synaptic transmission GO:0050804 141 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of protein kinase activity GO:0045859 105 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
carboxylic acid transport GO:0046942 115 0.012
cell activation GO:0001775 97 0.012
regulation of kinase activity GO:0043549 117 0.012
multi multicellular organism process GO:0044706 138 0.012
regulation of transferase activity GO:0051338 123 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
cellular response to peptide GO:1901653 133 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
oxidation reduction process GO:0055114 304 0.012
muscle system process GO:0003012 115 0.012
nucleotide catabolic process GO:0009166 139 0.012
gamete generation GO:0007276 124 0.012
liver development GO:0001889 90 0.012
signal release GO:0023061 145 0.012
regulation of catabolic process GO:0009894 113 0.012
hepaticobiliary system development GO:0061008 90 0.012
establishment of protein localization GO:0045184 141 0.012
cell cycle checkpoint GO:0000075 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
vesicle mediated transport GO:0016192 181 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
axonogenesis GO:0007409 71 0.012
purine containing compound catabolic process GO:0072523 138 0.012
neuron death GO:0070997 127 0.012
sequestering of calcium ion GO:0051208 8 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to amino acid GO:0043200 75 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
cytoskeleton organization GO:0007010 111 0.011
gliogenesis GO:0042063 93 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
chromosome segregation GO:0007059 2 0.011
cell type specific apoptotic process GO:0097285 134 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
chemotaxis GO:0006935 66 0.011
axis specification GO:0009798 4 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of mapk cascade GO:0043408 116 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
protein transport GO:0015031 132 0.011
cellular protein localization GO:0034613 122 0.011
wound healing GO:0042060 122 0.011
positive regulation of locomotion GO:0040017 102 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of secretion GO:0051047 140 0.011
actin filament based process GO:0030029 86 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
positive regulation of ion transport GO:0043270 94 0.011
organic anion transport GO:0015711 132 0.011
forebrain development GO:0030900 98 0.011
rho protein signal transduction GO:0007266 11 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
taxis GO:0042330 67 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
hormone secretion GO:0046879 115 0.011
cell adhesion GO:0007155 110 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
organophosphate catabolic process GO:0046434 148 0.011
organic acid transport GO:0015849 116 0.011
appendage morphogenesis GO:0035107 4 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to temperature stimulus GO:0009266 94 0.011
biological adhesion GO:0022610 110 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
cell growth GO:0016049 104 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
epithelium development GO:0060429 96 0.010
carbohydrate metabolic process GO:0005975 130 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of cell migration GO:0030334 128 0.010
cytokine biosynthetic process GO:0042089 3 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
chemosensory behavior GO:0007635 2 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
motor neuron axon guidance GO:0008045 1 0.010
gastrulation GO:0007369 2 0.010
muscle structure development GO:0061061 87 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
membrane organization GO:0061024 94 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to organophosphorus GO:0046683 102 0.010
peptide transport GO:0015833 97 0.010
lipid storage GO:0019915 1 0.010
cell cycle GO:0007049 101 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
glycosyl compound catabolic process GO:1901658 126 0.010

Siglec1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.010
disease of cellular proliferation DOID:14566 0 0.010