Rattus norvegicus

0 known processes

Afap1l2

actin filament associated protein 1-like 2

(Aliases: RGD1310668)

Afap1l2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 110 0.117
cellular component movement GO:0006928 248 0.090
non canonical wnt signaling pathway GO:0035567 3 0.088
gland development GO:0048732 155 0.082
cellular component biogenesis GO:0044085 368 0.079
cellular component assembly GO:0022607 360 0.075
nucleic acid templated transcription GO:0097659 379 0.074
Human
regulation of cellular component movement GO:0051270 150 0.073
anatomical structure morphogenesis GO:0009653 298 0.069
positive regulation of intracellular signal transduction GO:1902533 138 0.068
regulation of signal transduction GO:0009966 318 0.067
Human
regulation of molecular function GO:0065009 398 0.058
Human
biological adhesion GO:0022610 110 0.057
organic substance catabolic process GO:1901575 316 0.054
motor neuron axon guidance GO:0008045 1 0.053
positive regulation of phosphate metabolic process GO:0045937 262 0.053
Human
regulation of cellular component organization GO:0051128 368 0.052
positive regulation of developmental process GO:0051094 283 0.051
regulation of rna biosynthetic process GO:2001141 381 0.051
Human
regulation of canonical wnt signaling pathway GO:0060828 4 0.051
positive regulation of signaling GO:0023056 270 0.049
Human
cell projection organization GO:0030030 302 0.048
myelination GO:0042552 39 0.048
axon ensheathment GO:0008366 40 0.047
cellular response to oxygen containing compound GO:1901701 386 0.046
catabolic process GO:0009056 351 0.046
neuron development GO:0048666 286 0.045
positive regulation of cell communication GO:0010647 271 0.044
Human
multicellular organismal signaling GO:0035637 44 0.043
regulation of anatomical structure morphogenesis GO:0022603 141 0.043
positive regulation of phosphorylation GO:0042327 177 0.043
Human
response to peptide hormone GO:0043434 278 0.042
organic acid metabolic process GO:0006082 292 0.041
organophosphate metabolic process GO:0019637 370 0.041
gliogenesis GO:0042063 93 0.041
response to toxic substance GO:0009636 133 0.040
neuron differentiation GO:0030182 368 0.040
action potential GO:0001508 54 0.039
response to nutrient levels GO:0031667 370 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
localization of cell GO:0051674 202 0.038
organelle organization GO:0006996 266 0.038
regulation of transferase activity GO:0051338 123 0.038
Human
positive regulation of catalytic activity GO:0043085 184 0.038
Human
cell migration GO:0016477 197 0.038
positive regulation of cellular component movement GO:0051272 102 0.037
cellular response to lipid GO:0071396 201 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
Human
regulation of phosphorylation GO:0042325 248 0.037
Human
regulation of phosphorus metabolic process GO:0051174 349 0.036
Human
regulation of multicellular organismal development GO:2000026 376 0.036
cellular amino acid metabolic process GO:0006520 107 0.035
head development GO:0060322 247 0.035
amine metabolic process GO:0009308 38 0.034
positive regulation of cell death GO:0010942 184 0.034
reproductive process GO:0022414 372 0.034
protein complex biogenesis GO:0070271 263 0.034
central nervous system development GO:0007417 311 0.033
cell substrate adhesion GO:0031589 29 0.033
intracellular signal transduction GO:0035556 314 0.033
locomotion GO:0040011 237 0.033
neuron projection development GO:0031175 273 0.033
apoptotic process GO:0006915 381 0.033
regulation of phosphate metabolic process GO:0019220 349 0.032
Human
positive regulation of molecular function GO:0044093 230 0.032
Human
brain development GO:0007420 247 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
protein complex subunit organization GO:0071822 302 0.031
glial cell differentiation GO:0010001 65 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
Human
gastrulation GO:0007369 2 0.031
regulation of cell motility GO:2000145 131 0.031
response to extracellular stimulus GO:0009991 380 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
Human
negative regulation of response to stimulus GO:0048585 155 0.030
wnt signaling pathway calcium modulating pathway GO:0007223 1 0.030
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.030
response to wounding GO:0009611 254 0.029
regulation of rna metabolic process GO:0051252 391 0.029
Human
regulation of nervous system development GO:0051960 264 0.028
regulation of membrane potential GO:0042391 110 0.028
single organism reproductive process GO:0044702 297 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
positive regulation of apoptotic process GO:0043065 154 0.027
protein phosphorylation GO:0006468 345 0.027
Human
negative regulation of nervous system development GO:0051961 79 0.027
small gtpase mediated signal transduction GO:0007264 36 0.027
regulation of neuron differentiation GO:0045664 208 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
rna metabolic process GO:0016070 406 0.026
Human
cell cell signaling GO:0007267 335 0.025
anterior posterior pattern specification GO:0009952 1 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
transmission of nerve impulse GO:0019226 42 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
Human
metal ion homeostasis GO:0055065 186 0.025
hepaticobiliary system development GO:0061008 90 0.025
single organism organelle organization GO:1902589 180 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
cell morphogenesis GO:0000902 142 0.025
axon development GO:0061564 96 0.025
response to oxygen levels GO:0070482 265 0.025
regulation of protein kinase activity GO:0045859 105 0.025
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
Human
programmed cell death GO:0012501 392 0.024
regulation of transcription dna templated GO:0006355 374 0.024
Human
regulation of apoptotic process GO:0042981 335 0.024
protein oligomerization GO:0051259 191 0.024
regulation of synaptic transmission GO:0050804 141 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
Human
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of cell projection organization GO:0031344 175 0.023
cellular component morphogenesis GO:0032989 155 0.023
response to estradiol GO:0032355 164 0.023
cell part morphogenesis GO:0032990 123 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
Human
cell cycle GO:0007049 101 0.023
Human
negative regulation of multicellular organismal process GO:0051241 203 0.023
ensheathment of neurons GO:0007272 40 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
response to estrogen GO:0043627 232 0.023
protein localization GO:0008104 191 0.023
response to insulin GO:0032868 133 0.023
regulation of protein metabolic process GO:0051246 289 0.023
Human
negative regulation of osteoblast differentiation GO:0045668 2 0.022
regulation of cell development GO:0060284 263 0.022
cellular catabolic process GO:0044248 295 0.022
oxoacid metabolic process GO:0043436 290 0.022
cytoskeleton organization GO:0007010 111 0.022
cytosolic calcium ion homeostasis GO:0051480 140 0.022
regulation of cell differentiation GO:0045595 320 0.022
single organism catabolic process GO:0044712 283 0.022
positive regulation of protein modification process GO:0031401 142 0.022
Human
cell morphogenesis involved in differentiation GO:0000904 119 0.022
cellular response to alcohol GO:0097306 87 0.022
homeostatic process GO:0042592 331 0.022
regulation of cell proliferation GO:0042127 359 0.022
regulation of neuron projection development GO:0010975 161 0.022
regulation of programmed cell death GO:0043067 341 0.022
epithelium development GO:0060429 96 0.021
regulation of homeostatic process GO:0032844 101 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
synaptic transmission GO:0007268 235 0.021
neuronal action potential GO:0019228 35 0.021
positive regulation of signal transduction GO:0009967 175 0.020
Human
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of mapk cascade GO:0043408 116 0.020
transcription dna templated GO:0006351 377 0.020
Human
multi organism reproductive process GO:0044703 262 0.020
response to decreased oxygen levels GO:0036293 237 0.020
nucleotide metabolic process GO:0009117 279 0.020
cellular protein localization GO:0034613 122 0.020
regulation of locomotion GO:0040012 148 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
metanephric s shaped body morphogenesis GO:0072284 2 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
Human
reproductive structure development GO:0048608 128 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cell motility GO:0048870 202 0.020
response to glucocorticoid GO:0051384 223 0.019
taxis GO:0042330 67 0.019
cellular macromolecule localization GO:0070727 122 0.019
cellular amine metabolic process GO:0044106 38 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
response to nutrient GO:0007584 248 0.019
cation transport GO:0006812 382 0.019
regulation of stem cell differentiation GO:2000736 2 0.019
response to hypoxia GO:0001666 231 0.019
establishment of tissue polarity GO:0007164 2 0.019
positive regulation of protein metabolic process GO:0051247 178 0.018
Human
intracellular transport GO:0046907 185 0.018
ras protein signal transduction GO:0007265 29 0.018
neurological system process GO:0050877 219 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of body fluid levels GO:0050878 90 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
Human
regulation of catabolic process GO:0009894 113 0.018
regulation of neurogenesis GO:0050767 247 0.018
cellular response to steroid hormone stimulus GO:0071383 93 0.018
regulation of cell migration GO:0030334 128 0.018
cellular response to external stimulus GO:0071496 118 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
regulation of catalytic activity GO:0050790 304 0.018
Human
regulation of establishment of planar polarity GO:0090175 2 0.018
cellular response to stress GO:0033554 269 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
Human
cellular response to peptide GO:1901653 133 0.017
macromolecule localization GO:0033036 252 0.017
appendage morphogenesis GO:0035107 4 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
regulation of cell adhesion GO:0030155 52 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
response to vitamin GO:0033273 131 0.017
forebrain development GO:0030900 98 0.017
ion homeostasis GO:0050801 212 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
Human
regulation of synaptic plasticity GO:0048167 70 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
positive regulation of mapk cascade GO:0043410 92 0.016
cellular ketone metabolic process GO:0042180 51 0.016
membrane organization GO:0061024 94 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.016
female pregnancy GO:0007565 122 0.016
single organismal cell cell adhesion GO:0016337 42 0.016
protein transport GO:0015031 132 0.016
single organism cell adhesion GO:0098602 46 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
positive regulation of kinase activity GO:0033674 77 0.016
Human
purine containing compound metabolic process GO:0072521 253 0.016
rna biosynthetic process GO:0032774 380 0.016
Human
response to ketone GO:1901654 182 0.016
response to corticosteroid GO:0031960 235 0.016
nucleoside metabolic process GO:0009116 179 0.016
response to acid chemical GO:0001101 222 0.016
positive regulation of gene expression GO:0010628 244 0.016
Human
macromolecular complex assembly GO:0065003 273 0.016
establishment of protein localization GO:0045184 141 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
proteolysis GO:0006508 175 0.015
cell activation GO:0001775 97 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
cellular homeostasis GO:0019725 252 0.015
regulation of response to stress GO:0080134 126 0.015
negative regulation of signaling GO:0023057 157 0.015
regulation of system process GO:0044057 208 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of behavior GO:0050795 61 0.015
regulation of response to external stimulus GO:0032101 106 0.015
actin filament based process GO:0030029 86 0.015
response to peptide GO:1901652 292 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
neuron death GO:0070997 127 0.015
growth GO:0040007 165 0.015
positive regulation of transferase activity GO:0051347 81 0.015
Human
wound healing GO:0042060 122 0.014
positive regulation of cell migration GO:0030335 96 0.014
cell junction organization GO:0034330 21 0.014
liver development GO:0001889 90 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
respiratory system development GO:0060541 45 0.014
chemical homeostasis GO:0048878 292 0.014
cell matrix adhesion GO:0007160 19 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
Human
cardiovascular system development GO:0072358 134 0.014
synapse assembly GO:0007416 29 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
Human
positive regulation of cell development GO:0010720 176 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
digestive tract development GO:0048565 39 0.013
positive regulation of nervous system development GO:0051962 178 0.013
axis specification GO:0009798 4 0.013
positive regulation of cytokine production GO:0001819 42 0.013
Human
response to ethanol GO:0045471 162 0.013
axonogenesis GO:0007409 71 0.013
aging GO:0007568 241 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to oxidative stress GO:0006979 186 0.013
ovulation cycle GO:0042698 67 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
actin cytoskeleton organization GO:0030036 73 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
Human
single organism biosynthetic process GO:0044711 342 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
multicellular organism reproduction GO:0032504 233 0.013
regulation of response to wounding GO:1903034 69 0.012
mitotic spindle organization GO:0007052 2 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of cell death GO:0060548 229 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
regulation of secretion GO:0051046 224 0.012
regulation of cytokine production GO:0001817 56 0.012
Human
mapk cascade GO:0000165 140 0.012
response to metal ion GO:0010038 253 0.012
sex differentiation GO:0007548 113 0.012
salivary gland development GO:0007431 3 0.012
chemotaxis GO:0006935 66 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
synapse organization GO:0050808 46 0.012
positive regulation of catabolic process GO:0009896 78 0.012
formation of primary germ layer GO:0001704 1 0.012
single organism intracellular transport GO:1902582 166 0.012
s shaped body morphogenesis GO:0072050 2 0.012
response to inorganic substance GO:0010035 377 0.012
response to growth factor GO:0070848 189 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
embryonic hindlimb morphogenesis GO:0035116 2 0.012
calcium ion transport GO:0006816 131 0.012
neural crest cell differentiation GO:0014033 2 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of locomotion GO:0040017 102 0.012
positive regulation of cell adhesion GO:0045785 30 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
regulation of intracellular transport GO:0032386 65 0.012
myoblast fusion GO:0007520 2 0.011
organ regeneration GO:0031100 101 0.011
cytoplasmic transport GO:0016482 115 0.011
reproductive system development GO:0061458 128 0.011
single organism membrane organization GO:0044802 74 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
gonad development GO:0008406 104 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
muscle contraction GO:0006936 88 0.011
digestive system development GO:0055123 41 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
Human
cellular lipid metabolic process GO:0044255 208 0.011
developmental process involved in reproduction GO:0003006 159 0.011
circulatory system development GO:0072359 134 0.011
regulation of map kinase activity GO:0043405 53 0.011
platelet aggregation GO:0070527 4 0.011
positive regulation of transport GO:0051050 245 0.011
positive regulation of neuron death GO:1901216 43 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of growth GO:0040008 105 0.011
secretion GO:0046903 307 0.011
regulation of hydrolase activity GO:0051336 143 0.011
angiogenesis GO:0001525 53 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
regulation of protein modification process GO:0031399 194 0.011
Human
heart morphogenesis GO:0003007 3 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
response to temperature stimulus GO:0009266 94 0.011
cellular response to acid chemical GO:0071229 75 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
hemostasis GO:0007599 26 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
protein homooligomerization GO:0051260 91 0.011
neural crest cell development GO:0014032 2 0.011
regeneration GO:0031099 163 0.011
transmembrane transport GO:0055085 412 0.011
purine containing compound catabolic process GO:0072523 138 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
Human
kidney mesenchyme development GO:0072074 2 0.010
rho protein signal transduction GO:0007266 11 0.010
response to external biotic stimulus GO:0043207 221 0.010
leukocyte migration GO:0050900 38 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
tube formation GO:0035148 3 0.010
coagulation GO:0050817 28 0.010
negative regulation of cell development GO:0010721 82 0.010
palate development GO:0060021 2 0.010

Afap1l2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.011
sensory system disease DOID:0050155 0 0.011