Rattus norvegicus

26 known processes

Sipa1

signal-induced proliferation-associated 1

(Aliases: Spa1)

Sipa1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.102
transcription dna templated GO:0006351 377 0.092
immune system process GO:0002376 204 0.088
regulation of rna metabolic process GO:0051252 391 0.087
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.086
positive regulation of biosynthetic process GO:0009891 319 0.081
regulation of nucleic acid templated transcription GO:1903506 380 0.081
nucleic acid templated transcription GO:0097659 379 0.074
rna metabolic process GO:0016070 406 0.073
positive regulation of nucleic acid templated transcription GO:1903508 197 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
rna biosynthetic process GO:0032774 380 0.060
positive regulation of rna metabolic process GO:0051254 203 0.059
positive regulation of transcription dna templated GO:0045893 197 0.059
regulation of phosphorus metabolic process GO:0051174 349 0.056
cellular response to stress GO:0033554 269 0.056
regulation of multicellular organismal development GO:2000026 376 0.055
apoptotic process GO:0006915 381 0.055
positive regulation of rna biosynthetic process GO:1902680 197 0.053
cellular component biogenesis GO:0044085 368 0.052
regulation of cell differentiation GO:0045595 320 0.051
positive regulation of gene expression GO:0010628 244 0.048
carbohydrate derivative metabolic process GO:1901135 346 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
homeostatic process GO:0042592 331 0.046
cellular component assembly GO:0022607 360 0.045
intracellular signal transduction GO:0035556 314 0.045
brain development GO:0007420 247 0.044
behavior GO:0007610 205 0.044
cellular ion homeostasis GO:0006873 184 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
organic acid metabolic process GO:0006082 292 0.039
regulation of cellular component organization GO:0051128 368 0.039
nucleoside triphosphate metabolic process GO:0009141 144 0.039
organophosphate metabolic process GO:0019637 370 0.038
anterior posterior pattern specification GO:0009952 1 0.038
response to growth factor GO:0070848 189 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.038
catabolic process GO:0009056 351 0.037
programmed cell death GO:0012501 392 0.037
response to nutrient levels GO:0031667 370 0.036
calcium ion homeostasis GO:0055074 162 0.036
response to monosaccharide GO:0034284 159 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
positive regulation of developmental process GO:0051094 283 0.035
response to external biotic stimulus GO:0043207 221 0.035
sensory organ development GO:0007423 74 0.035
oxoacid metabolic process GO:0043436 290 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.033
regulation of cell development GO:0060284 263 0.033
camera type eye development GO:0043010 48 0.032
calcium ion transport GO:0006816 131 0.032
cellular amine metabolic process GO:0044106 38 0.032
central nervous system development GO:0007417 311 0.032
cellular homeostasis GO:0019725 252 0.032
negative regulation of metabolic process GO:0009892 331 0.031
head development GO:0060322 247 0.031
positive regulation of cell differentiation GO:0045597 217 0.031
reproduction GO:0000003 245 0.031
purine ribonucleoside metabolic process GO:0046128 168 0.031
ribose phosphate metabolic process GO:0019693 235 0.031
divalent metal ion transport GO:0070838 132 0.031
response to inorganic substance GO:0010035 377 0.030
single organism reproductive process GO:0044702 297 0.030
negative regulation of gene expression GO:0010629 199 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.029
chemical homeostasis GO:0048878 292 0.028
reproductive process GO:0022414 372 0.028
ras protein signal transduction GO:0007265 29 0.028
protein localization GO:0008104 191 0.028
axis specification GO:0009798 4 0.028
regulation of programmed cell death GO:0043067 341 0.028
regulation of secretion by cell GO:1903530 208 0.027
response to biotic stimulus GO:0009607 226 0.027
response to extracellular stimulus GO:0009991 380 0.027
regulation of purine nucleotide metabolic process GO:1900542 115 0.027
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
neurological system process GO:0050877 219 0.026
regulation of apoptotic process GO:0042981 335 0.026
protein complex subunit organization GO:0071822 302 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
single organism catabolic process GO:0044712 283 0.025
regulation of neuron differentiation GO:0045664 208 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
cellular chemical homeostasis GO:0055082 247 0.025
ion homeostasis GO:0050801 212 0.025
cellular amino acid metabolic process GO:0006520 107 0.024
purine containing compound metabolic process GO:0072521 253 0.024
organelle organization GO:0006996 266 0.024
response to metal ion GO:0010038 253 0.024
metal ion homeostasis GO:0055065 186 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
secretion GO:0046903 307 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
regulation of neurogenesis GO:0050767 247 0.024
cation transport GO:0006812 382 0.024
nucleoside metabolic process GO:0009116 179 0.024
regulation of neuron projection development GO:0010975 161 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
negative regulation of cell death GO:0060548 229 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
regulation of signal transduction GO:0009966 318 0.023
positive regulation of cell development GO:0010720 176 0.023
protein complex assembly GO:0006461 263 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
regulation of ion transport GO:0043269 245 0.023
response to hexose GO:0009746 144 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
neuron differentiation GO:0030182 368 0.022
regulation of transcription dna templated GO:0006355 374 0.022
sequestering of calcium ion GO:0051208 8 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
response to carbohydrate GO:0009743 183 0.022
cellular component movement GO:0006928 248 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
regulation of secretion GO:0051046 224 0.022
macromolecule localization GO:0033036 252 0.022
transmembrane transport GO:0055085 412 0.021
response to cytokine GO:0034097 215 0.021
secretion by cell GO:0032940 248 0.021
nitrogen compound transport GO:0071705 229 0.021
single organism biosynthetic process GO:0044711 342 0.021
macromolecular complex assembly GO:0065003 273 0.021
multi organism reproductive process GO:0044703 262 0.021
vesicle mediated transport GO:0016192 181 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
negative regulation of transport GO:0051051 136 0.021
b cell differentiation GO:0030183 2 0.021
lipid metabolic process GO:0006629 283 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
metal ion transport GO:0030001 289 0.020
protein complex biogenesis GO:0070271 263 0.020
positive regulation of transport GO:0051050 245 0.020
multicellular organism reproduction GO:0032504 233 0.020
intracellular transport GO:0046907 185 0.020
cation homeostasis GO:0055080 195 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
organophosphate catabolic process GO:0046434 148 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
cellular catabolic process GO:0044248 295 0.019
nucleotide metabolic process GO:0009117 279 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
single organism intracellular transport GO:1902582 166 0.019
maintenance of location GO:0051235 17 0.019
sequestering of metal ion GO:0051238 9 0.019
single organism behavior GO:0044708 130 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
cellular lipid metabolic process GO:0044255 208 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
multicellular organism growth GO:0035264 1 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cell type specific apoptotic process GO:0097285 134 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
embryonic pattern specification GO:0009880 1 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
amine metabolic process GO:0009308 38 0.017
cell morphogenesis GO:0000902 142 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
dna metabolic process GO:0006259 96 0.017
cell migration GO:0016477 197 0.016
single organism organelle organization GO:1902589 180 0.016
regulation of homeostatic process GO:0032844 101 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
aging GO:0007568 241 0.016
regulation of nervous system development GO:0051960 264 0.016
response to other organism GO:0051707 220 0.016
positive regulation of immunoglobulin production GO:0002639 4 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
response to glucocorticoid GO:0051384 223 0.016
growth GO:0040007 165 0.016
response to hypoxia GO:0001666 231 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
b cell mediated immunity GO:0019724 4 0.016
defense response GO:0006952 194 0.016
renal system development GO:0072001 67 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
regulation of isotype switching GO:0045191 1 0.016
organ morphogenesis GO:0009887 75 0.015
regeneration GO:0031099 163 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
negative regulation of signal transduction GO:0009968 83 0.015
response to acid chemical GO:0001101 222 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
regulation of cellular localization GO:0060341 263 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
developmental process involved in reproduction GO:0003006 159 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
response to ketone GO:1901654 182 0.015
response to decreased oxygen levels GO:0036293 237 0.015
positive regulation of molecular function GO:0044093 230 0.015
rhythmic process GO:0048511 156 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
organic substance catabolic process GO:1901575 316 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
localization of cell GO:0051674 202 0.014
cellular response to lipid GO:0071396 201 0.014
ion transmembrane transport GO:0034220 365 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
divalent inorganic cation transport GO:0072511 134 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
wound healing GO:0042060 122 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
regulation of immunoglobulin production GO:0002637 4 0.014
cell motility GO:0048870 202 0.014
cytoplasmic transport GO:0016482 115 0.014
response to peptide GO:1901652 292 0.014
cell cycle GO:0007049 101 0.014
protein phosphorylation GO:0006468 345 0.014
negative regulation of developmental process GO:0051093 125 0.014
nucleoside catabolic process GO:0009164 126 0.013
regulation of molecular function GO:0065009 398 0.013
mapk cascade GO:0000165 140 0.013
positive regulation of gtpase activity GO:0043547 47 0.013
response to bacterium GO:0009617 200 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
cell cycle checkpoint GO:0000075 2 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
immunoglobulin mediated immune response GO:0016064 4 0.013
cellular ketone metabolic process GO:0042180 51 0.013
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.013
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of ras gtpase activity GO:0032320 28 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to glucose GO:0009749 136 0.013
regulation of phosphorylation GO:0042325 248 0.013
gamete generation GO:0007276 124 0.013
regulation of blood vessel endothelial cell migration GO:0043535 4 0.013
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of cell cycle GO:0051726 73 0.012
response to nutrient GO:0007584 248 0.012
response to estrogen GO:0043627 232 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
immune system development GO:0002520 41 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
response to ethanol GO:0045471 162 0.012
glycerolipid metabolic process GO:0046486 67 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
phospholipid metabolic process GO:0006644 61 0.012
cardiovascular system development GO:0072358 134 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
response to radiation GO:0009314 137 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
aromatic compound catabolic process GO:0019439 168 0.012
regulation of organelle organization GO:0033043 80 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
response to corticosteroid GO:0031960 235 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
digestive system development GO:0055123 41 0.012
tissue development GO:0009888 252 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of gtpase activity GO:0043087 57 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
negative regulation of homeostatic process GO:0032845 47 0.011
eye development GO:0001654 50 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to oxygen levels GO:0070482 265 0.011
cell activation GO:0001775 97 0.011
regulation of membrane potential GO:0042391 110 0.011
multi multicellular organism process GO:0044706 138 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of catalytic activity GO:0050790 304 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
cell projection organization GO:0030030 302 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
regulation of embryonic development GO:0045995 2 0.011
positive regulation of nervous system development GO:0051962 178 0.011
sex differentiation GO:0007548 113 0.011
odontogenesis GO:0042476 32 0.011
leukocyte differentiation GO:0002521 30 0.011
neuron projection development GO:0031175 273 0.011
calcium ion transport into cytosol GO:0060402 38 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
chromatin modification GO:0016568 33 0.011
protein oligomerization GO:0051259 191 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
positive regulation of catabolic process GO:0009896 78 0.011
response to wounding GO:0009611 254 0.011
nucleotide catabolic process GO:0009166 139 0.011
response to peptide hormone GO:0043434 278 0.010
regulation of calcium ion transport GO:0051924 77 0.010
response to transforming growth factor beta GO:0071559 46 0.010
cellular protein complex assembly GO:0043623 44 0.010
positive regulation of signal transduction GO:0009967 175 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
locomotion GO:0040011 237 0.010
embryonic axis specification GO:0000578 1 0.010
cellular protein localization GO:0034613 122 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
regulation of ras protein signal transduction GO:0046578 45 0.010
positive regulation of cell death GO:0010942 184 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
cellular response to alcohol GO:0097306 87 0.010
bmp signaling pathway GO:0030509 4 0.010

Sipa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.013