Rattus norvegicus

0 known processes

Spint2

serine peptidase inhibitor, Kunitz type, 2

(Aliases: Pb,MGC72638,HAI-2)

Spint2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate metabolic process GO:0019637 370 0.088
head development GO:0060322 247 0.059
chemical homeostasis GO:0048878 292 0.052
protein complex biogenesis GO:0070271 263 0.051
regulation of apoptotic process GO:0042981 335 0.050
response to acid chemical GO:0001101 222 0.049
immune system process GO:0002376 204 0.048
neuron development GO:0048666 286 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.043
response to peptide GO:1901652 292 0.043
catabolic process GO:0009056 351 0.040
nucleoside phosphate metabolic process GO:0006753 283 0.039
neuron differentiation GO:0030182 368 0.038
regulation of cellular component organization GO:0051128 368 0.037
organophosphate biosynthetic process GO:0090407 143 0.037
cellular homeostasis GO:0019725 252 0.037
central nervous system development GO:0007417 311 0.037
carbohydrate metabolic process GO:0005975 130 0.036
reproductive process GO:0022414 372 0.036
oxidation reduction process GO:0055114 304 0.036
cell projection organization GO:0030030 302 0.036
cellular amine metabolic process GO:0044106 38 0.036
regulation of cell projection organization GO:0031344 175 0.036
response to hexose GO:0009746 144 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of programmed cell death GO:0043067 341 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
protein phosphorylation GO:0006468 345 0.034
cellular chemical homeostasis GO:0055082 247 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
programmed cell death GO:0012501 392 0.033
regulation of cell differentiation GO:0045595 320 0.032
amine metabolic process GO:0009308 38 0.032
regulation of molecular function GO:0065009 398 0.032
negative regulation of signaling GO:0023057 157 0.032
brain development GO:0007420 247 0.032
protein complex subunit organization GO:0071822 302 0.032
response to other organism GO:0051707 220 0.032
response to ketone GO:1901654 182 0.031
response to oxygen levels GO:0070482 265 0.031
single organism reproductive process GO:0044702 297 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.030
protein complex assembly GO:0006461 263 0.030
cellular response to hormone stimulus GO:0032870 247 0.029
cellular component biogenesis GO:0044085 368 0.029
neuron projection development GO:0031175 273 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
single organism carbohydrate metabolic process GO:0044723 118 0.028
homeostatic process GO:0042592 331 0.027
cell migration GO:0016477 197 0.027
forebrain development GO:0030900 98 0.027
nitrogen compound transport GO:0071705 229 0.026
wound healing GO:0042060 122 0.026
organonitrogen compound biosynthetic process GO:1901566 167 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
regulation of cell development GO:0060284 263 0.025
gland development GO:0048732 155 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
response to fatty acid GO:0070542 65 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
response to carbohydrate GO:0009743 183 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
regulation of neurogenesis GO:0050767 247 0.024
multicellular organism reproduction GO:0032504 233 0.024
response to inorganic substance GO:0010035 377 0.023
apoptotic process GO:0006915 381 0.023
organic substance catabolic process GO:1901575 316 0.023
organelle organization GO:0006996 266 0.023
positive regulation of camp metabolic process GO:0030816 31 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
cyclic nucleotide metabolic process GO:0009187 80 0.022
regulation of cell proliferation GO:0042127 359 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
multi organism reproductive process GO:0044703 262 0.022
response to purine containing compound GO:0014074 126 0.022
regulation of locomotion GO:0040012 148 0.022
macromolecule localization GO:0033036 252 0.021
regulation of neuron projection development GO:0010975 161 0.021
acrosome assembly GO:0001675 3 0.021
localization of cell GO:0051674 202 0.021
response to wounding GO:0009611 254 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular response to lipid GO:0071396 201 0.021
reproductive system development GO:0061458 128 0.020
cellular catabolic process GO:0044248 295 0.020
single organism biosynthetic process GO:0044711 342 0.020
regulation of signal transduction GO:0009966 318 0.020
purine containing compound metabolic process GO:0072521 253 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
response to retinoic acid GO:0032526 63 0.020
regulation of cellular component movement GO:0051270 150 0.020
positive regulation of developmental process GO:0051094 283 0.019
single organism catabolic process GO:0044712 283 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
cellular ketone metabolic process GO:0042180 51 0.019
cell motility GO:0048870 202 0.019
transmembrane transport GO:0055085 412 0.019
gamete generation GO:0007276 124 0.019
response to extracellular stimulus GO:0009991 380 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
positive regulation of signaling GO:0023056 270 0.019
anion transport GO:0006820 178 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
cation transport GO:0006812 382 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
protein autophosphorylation GO:0046777 66 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
negative regulation of molecular function GO:0044092 133 0.018
negative regulation of cell death GO:0060548 229 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
ion transmembrane transport GO:0034220 365 0.018
macromolecular complex assembly GO:0065003 273 0.018
peptide secretion GO:0002790 86 0.018
response to external biotic stimulus GO:0043207 221 0.017
regulation of nervous system development GO:0051960 264 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
cellular component assembly GO:0022607 360 0.017
ribonucleotide biosynthetic process GO:0009260 85 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
cofactor metabolic process GO:0051186 95 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
intracellular signal transduction GO:0035556 314 0.017
negative regulation of cell communication GO:0010648 158 0.017
regulation of catalytic activity GO:0050790 304 0.017
response to nutrient levels GO:0031667 370 0.017
developmental process involved in reproduction GO:0003006 159 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
regulation of protein metabolic process GO:0051246 289 0.016
negative regulation of metabolic process GO:0009892 331 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
cellular component movement GO:0006928 248 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
regulation of immune system process GO:0002682 123 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
positive regulation of gene expression GO:0010628 244 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
sexual reproduction GO:0019953 148 0.016
oxoacid metabolic process GO:0043436 290 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
regulation of cell migration GO:0030334 128 0.016
secretion by cell GO:0032940 248 0.015
sensory organ development GO:0007423 74 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of cell development GO:0010720 176 0.015
response to peptide hormone GO:0043434 278 0.015
response to glucose GO:0009749 136 0.015
response to testosterone GO:0033574 55 0.015
ion homeostasis GO:0050801 212 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of neuron differentiation GO:0045664 208 0.015
signal release GO:0023061 145 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
calcium ion homeostasis GO:0055074 162 0.015
metal ion transport GO:0030001 289 0.014
metal ion homeostasis GO:0055065 186 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
response to ethanol GO:0045471 162 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
cellular amide metabolic process GO:0043603 44 0.014
cellular cation homeostasis GO:0030003 180 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
heart morphogenesis GO:0003007 3 0.014
regulation of kinase activity GO:0043549 117 0.014
cell cell signaling GO:0007267 335 0.014
regulation of rna metabolic process GO:0051252 391 0.014
retinoic acid metabolic process GO:0042573 13 0.014
carboxylic acid transport GO:0046942 115 0.014
protein oligomerization GO:0051259 191 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
cellular ion homeostasis GO:0006873 184 0.014
amide transport GO:0042886 105 0.014
arp2 3 complex mediated actin nucleation GO:0034314 2 0.014
regulation of cellular localization GO:0060341 263 0.014
response to glucocorticoid GO:0051384 223 0.014
lipid metabolic process GO:0006629 283 0.014
response to hypoxia GO:0001666 231 0.014
response to toxic substance GO:0009636 133 0.014
organic acid metabolic process GO:0006082 292 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
tissue development GO:0009888 252 0.014
cellular response to stress GO:0033554 269 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
macroautophagy GO:0016236 4 0.013
regulation of hormone levels GO:0010817 187 0.013
kidney development GO:0001822 67 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
cellular response to drug GO:0035690 30 0.013
response to axon injury GO:0048678 59 0.013
response to organophosphorus GO:0046683 102 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of cell motility GO:2000145 131 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
tube development GO:0035295 89 0.013
intracellular transport GO:0046907 185 0.013
reproduction GO:0000003 245 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
regulation of body fluid levels GO:0050878 90 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
response to biotic stimulus GO:0009607 226 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of cell communication GO:0010647 271 0.012
cellular component morphogenesis GO:0032989 155 0.012
regulation of hormone secretion GO:0046883 106 0.012
gastrulation GO:0007369 2 0.012
cellular response to acid chemical GO:0071229 75 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
regulation of phosphorylation GO:0042325 248 0.012
proteolysis GO:0006508 175 0.012
response to growth factor GO:0070848 189 0.012
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
glycogen metabolic process GO:0005977 23 0.012
axis specification GO:0009798 4 0.012
male gamete generation GO:0048232 99 0.012
peptide hormone secretion GO:0030072 84 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
locomotion GO:0040011 237 0.012
peptide transport GO:0015833 97 0.012
regulation of peptide secretion GO:0002791 82 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
spermatogenesis GO:0007283 99 0.012
cellular response to nutrient levels GO:0031669 60 0.012
anion transmembrane transport GO:0098656 77 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
response to camp GO:0051591 91 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
organic acid transport GO:0015849 116 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
positive regulation of molecular function GO:0044093 230 0.011
glucan metabolic process GO:0044042 23 0.011
hormone secretion GO:0046879 115 0.011
coenzyme metabolic process GO:0006732 86 0.011
response to amine GO:0014075 46 0.011
regulation of immune response GO:0050776 55 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
renal system development GO:0072001 67 0.011
positive regulation of transport GO:0051050 245 0.011
transcription dna templated GO:0006351 377 0.011
camp metabolic process GO:0046058 63 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
regulation of synaptic transmission GO:0050804 141 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of camp metabolic process GO:0030814 43 0.011
response to corticosteroid GO:0031960 235 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
response to lipopolysaccharide GO:0032496 191 0.011
secretion GO:0046903 307 0.011
cytoplasmic transport GO:0016482 115 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
reproductive structure development GO:0048608 128 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.010
positive regulation of cell death GO:0010942 184 0.010
cellular lipid metabolic process GO:0044255 208 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
response to insulin GO:0032868 133 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
glucose homeostasis GO:0042593 75 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
regulation of cellular component size GO:0032535 51 0.010

Spint2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.027
disease of metabolism DOID:0014667 0 0.027
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013