Rattus norvegicus

37 known processes

Cyp2e1

cytochrome P450, family 2, subfamily e, polypeptide 1

(Aliases: Cyp2e)

Cyp2e1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chlorinated hydrocarbon metabolic process GO:0042196 4 0.856
Rat
oxoacid metabolic process GO:0043436 290 0.849
Rat
alkaloid metabolic process GO:0009820 3 0.794
Rat
long chain fatty acid metabolic process GO:0001676 32 0.771
Rat
carboxylic acid metabolic process GO:0019752 289 0.698
Rat
drug metabolic process GO:0017144 11 0.660
Human Rat
organic acid metabolic process GO:0006082 292 0.635
Rat
response to peptide GO:1901652 292 0.596
Rat
coenzyme metabolic process GO:0006732 86 0.511
exogenous drug catabolic process GO:0042738 1 0.484
halogenated hydrocarbon metabolic process GO:0042197 4 0.476
Rat
linoleic acid metabolic process GO:0043651 4 0.466
cellular amino acid metabolic process GO:0006520 107 0.374
cofactor metabolic process GO:0051186 95 0.372
cellular lipid metabolic process GO:0044255 208 0.371
nicotine metabolic process GO:0018933 1 0.354
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.344
trichloroethylene metabolic process GO:0018979 1 0.322
Rat
response to insulin GO:0032868 133 0.321
Rat
arachidonic acid metabolic process GO:0019369 20 0.283
Rat
drug catabolic process GO:0042737 1 0.268
sulfur compound metabolic process GO:0006790 70 0.267
liver development GO:0001889 90 0.260
Rat
naphthalene containing compound metabolic process GO:0090420 2 0.259
Rat
small molecule catabolic process GO:0044282 59 0.244
unsaturated fatty acid metabolic process GO:0033559 39 0.229
Rat
xenobiotic metabolic process GO:0006805 19 0.226
response to xenobiotic stimulus GO:0009410 23 0.225
lipid metabolic process GO:0006629 283 0.223
response to acid chemical GO:0001101 222 0.221
response to metal ion GO:0010038 253 0.189
Rat
catabolic process GO:0009056 351 0.181
response to peptide hormone GO:0043434 278 0.174
Rat
oxidation reduction process GO:0055114 304 0.174
alpha amino acid metabolic process GO:1901605 71 0.162
pyridine containing compound metabolic process GO:0072524 32 0.155
Rat
fatty acid metabolic process GO:0006631 99 0.148
Rat
lauric acid metabolic process GO:0048252 4 0.137
monocarboxylic acid metabolic process GO:0032787 152 0.135
Rat
cellular response to oxygen containing compound GO:1901701 386 0.134
gland development GO:0048732 155 0.124
Rat
epoxygenase p450 pathway GO:0019373 1 0.122
Rat
naphthalene metabolic process GO:0018931 2 0.119
Rat
steroid metabolic process GO:0008202 73 0.119
Human
cellular response to peptide GO:1901653 133 0.116
organ regeneration GO:0031100 101 0.114
regeneration GO:0031099 163 0.111
response to cesium ion GO:0010164 2 0.109
Rat
acylglycerol metabolic process GO:0006639 21 0.109
aromatic amino acid family catabolic process GO:0009074 7 0.106
cellular response to xenobiotic stimulus GO:0071466 19 0.101
fatty acid derivative metabolic process GO:1901568 38 0.100
Rat
cellular response to lipid GO:0071396 201 0.100
hepaticobiliary system development GO:0061008 90 0.095
Rat
neutral lipid metabolic process GO:0006638 21 0.094
amine metabolic process GO:0009308 38 0.091
regulation of phosphate metabolic process GO:0019220 349 0.088
icosanoid metabolic process GO:0006690 38 0.087
Rat
response to testosterone GO:0033574 55 0.083
Rat
response to toxic substance GO:0009636 133 0.080
nucleobase containing small molecule metabolic process GO:0055086 316 0.080
small molecule biosynthetic process GO:0044283 124 0.078
cellular catabolic process GO:0044248 295 0.076
response to ethanol GO:0045471 162 0.074
single organism biosynthetic process GO:0044711 342 0.070
development of primary sexual characteristics GO:0045137 107 0.067
response to inorganic substance GO:0010035 377 0.063
cellular ketone metabolic process GO:0042180 51 0.062
response to camp GO:0051591 91 0.060
organophosphate metabolic process GO:0019637 370 0.059
triglyceride metabolic process GO:0006641 21 0.059
response to sulfur dioxide GO:0010477 3 0.058
Rat
protein oligomerization GO:0051259 191 0.058
cellular response to external stimulus GO:0071496 118 0.057
monosaccharide metabolic process GO:0005996 61 0.057
regulation of cellular amino acid metabolic process GO:0006521 2 0.056
single organism catabolic process GO:0044712 283 0.056
secondary metabolic process GO:0019748 15 0.055
Rat
multi organism reproductive process GO:0044703 262 0.055
Rat
aromatic amino acid family metabolic process GO:0009072 9 0.054
glycerolipid metabolic process GO:0046486 67 0.054
response to oxygen levels GO:0070482 265 0.053
calcitriol biosynthetic process from calciol GO:0036378 2 0.052
neurological system process GO:0050877 219 0.052
response to glucocorticoid GO:0051384 223 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.051
regulation of cellular amine metabolic process GO:0033238 8 0.051
carboxylic acid biosynthetic process GO:0046394 83 0.051
single organism carbohydrate metabolic process GO:0044723 118 0.050
organic acid biosynthetic process GO:0016053 83 0.050
response to extracellular stimulus GO:0009991 380 0.049
protein complex biogenesis GO:0070271 263 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.048
response to transition metal nanoparticle GO:1990267 122 0.048
developmental process involved in reproduction GO:0003006 159 0.045
nitrogen compound transport GO:0071705 229 0.045
regulation of molecular function GO:0065009 398 0.044
organic hydroxy compound metabolic process GO:1901615 115 0.044
Rat
cellular macromolecule localization GO:0070727 122 0.044
response to nutrient levels GO:0031667 370 0.043
response to corticosteroid GO:0031960 235 0.041
regulation of hormone levels GO:0010817 187 0.039
response to estrogen GO:0043627 232 0.038
purine containing compound metabolic process GO:0072521 253 0.038
cellular amine metabolic process GO:0044106 38 0.038
protein homooligomerization GO:0051260 91 0.038
aromatic compound catabolic process GO:0019439 168 0.037
chemical homeostasis GO:0048878 292 0.037
cellular response to nitrogen compound GO:1901699 210 0.037
organic cyclic compound catabolic process GO:1901361 175 0.035
carbohydrate metabolic process GO:0005975 130 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.034
Rat
pyruvate metabolic process GO:0006090 27 0.034
hexose biosynthetic process GO:0019319 15 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
4 chlorobiphenyl metabolic process GO:0018880 1 0.031
response to insecticide GO:0017085 21 0.031
defense response GO:0006952 194 0.031
carboxylic acid catabolic process GO:0046395 49 0.030
nicotinamide nucleotide metabolic process GO:0046496 28 0.030
hexose metabolic process GO:0019318 58 0.030
establishment of tissue polarity GO:0007164 2 0.030
macromolecular complex assembly GO:0065003 273 0.029
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.029
phenylpropanoid metabolic process GO:0009698 5 0.029
Rat
cellular response to insulin stimulus GO:0032869 81 0.029
cellular response to organic cyclic compound GO:0071407 202 0.029
homeostatic process GO:0042592 331 0.029
thioester metabolic process GO:0035383 28 0.028
benzene containing compound metabolic process GO:0042537 22 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
gluconeogenesis GO:0006094 15 0.028
oxidoreduction coenzyme metabolic process GO:0006733 31 0.028
cellular hormone metabolic process GO:0034754 49 0.028
response to growth factor GO:0070848 189 0.028
response to starvation GO:0042594 59 0.027
central nervous system development GO:0007417 311 0.027
peptide transport GO:0015833 97 0.027
serine family amino acid biosynthetic process GO:0009070 4 0.026
regulation of phosphorylation GO:0042325 248 0.026
protein complex assembly GO:0006461 263 0.025
nucleotide metabolic process GO:0009117 279 0.025
response to platinum ion GO:0070541 4 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
response to nutrient GO:0007584 248 0.025
organic hydroxy compound biosynthetic process GO:1901617 51 0.025
Rat
cell cell signaling GO:0007267 335 0.024
reproductive process GO:0022414 372 0.024
Rat
ribonucleoside metabolic process GO:0009119 174 0.024
sulfation GO:0051923 2 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
hormone secretion GO:0046879 115 0.023
nucleoside metabolic process GO:0009116 179 0.023
aging GO:0007568 241 0.023
Rat
single organism reproductive process GO:0044702 297 0.023
biphenyl catabolic process GO:0070980 2 0.022
secretion GO:0046903 307 0.022
fluorene metabolic process GO:0018917 1 0.022
hormone transport GO:0009914 121 0.022
cellular response to testosterone stimulus GO:0071394 5 0.022
phenol containing compound metabolic process GO:0018958 30 0.022
Rat
monosaccharide biosynthetic process GO:0046364 16 0.022
choline transport GO:0015871 4 0.022
ion homeostasis GO:0050801 212 0.021
response to monosaccharide GO:0034284 159 0.021
protein tetramerization GO:0051262 38 0.021
amide transport GO:0042886 105 0.021
cellular response to iron ion starvation GO:0010106 1 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
biphenyl metabolic process GO:0018879 10 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
reproductive structure development GO:0048608 128 0.020
transmission of nerve impulse GO:0019226 42 0.020
cellular protein localization GO:0034613 122 0.020
peptidyl amino acid modification GO:0018193 126 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
t cell tolerance induction GO:0002517 3 0.020
response to organophosphorus GO:0046683 102 0.020
regulation of signal transduction GO:0009966 318 0.020
hormone catabolic process GO:0042447 2 0.019
heterocycle catabolic process GO:0046700 167 0.019
response to mercury ion GO:0046689 15 0.019
behavior GO:0007610 205 0.019
4 nitrophenol metabolic process GO:0018960 1 0.019
protein homotetramerization GO:0051289 25 0.018
positive regulation of tolerance induction GO:0002645 1 0.018
blood circulation GO:0008015 183 0.018
response to external biotic stimulus GO:0043207 221 0.018
cellular modified amino acid metabolic process GO:0006575 61 0.018
multi multicellular organism process GO:0044706 138 0.018
Rat
response to radiation GO:0009314 137 0.018
Rat
cellular component biogenesis GO:0044085 368 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
regulation of apoptotic process GO:0042981 335 0.017
dicarboxylic acid metabolic process GO:0043648 42 0.017
response to ionizing radiation GO:0010212 59 0.017
Rat
positive regulation of catalytic activity GO:0043085 184 0.017
multicellular organismal homeostasis GO:0048871 49 0.017
regulation of transferase activity GO:0051338 123 0.017
terpenoid metabolic process GO:0006721 37 0.017
Human Rat
antral ovarian follicle growth GO:0001547 3 0.017
peptidyl tyrosine modification GO:0018212 72 0.016
response to vitamin e GO:0033197 24 0.016
response to zinc ion GO:0010043 39 0.016
isoprenoid metabolic process GO:0006720 45 0.016
Human Rat
regulation of peptide transport GO:0090087 87 0.016
glucose metabolic process GO:0006006 52 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
regulation of programmed cell death GO:0043067 341 0.016
rhythmic process GO:0048511 156 0.016
insecticide metabolic process GO:0017143 4 0.016
regulation of gluconeogenesis GO:0006111 4 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
apoptotic process GO:0006915 381 0.016
regulation of catalytic activity GO:0050790 304 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
negative regulation of metabolic process GO:0009892 331 0.015
response to carbohydrate GO:0009743 183 0.015
negative regulation of innate immune response GO:0045824 4 0.015
response to purine containing compound GO:0014074 126 0.015
secondary alcohol metabolic process GO:1902652 2 0.015
response to lead ion GO:0010288 33 0.015
tolerance induction dependent upon immune response GO:0002461 2 0.015
response to biotic stimulus GO:0009607 226 0.015
action potential GO:0001508 54 0.015
organic substance catabolic process GO:1901575 316 0.015
reproduction GO:0000003 245 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
response to amino acid GO:0043200 75 0.014
reproductive system development GO:0061458 128 0.014
response to hexose GO:0009746 144 0.014
insulin secretion GO:0030073 69 0.014
regulation of protein modification process GO:0031399 194 0.014
lipid storage GO:0019915 1 0.014
sex differentiation GO:0007548 113 0.014
cellular modified amino acid catabolic process GO:0042219 1 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
anatomical structure homeostasis GO:0060249 29 0.014
programmed cell death GO:0012501 392 0.014
multicellular organism reproduction GO:0032504 233 0.014
response to ddt GO:0046680 1 0.013
coumarin metabolic process GO:0009804 5 0.013
Rat
androgen metabolic process GO:0008209 14 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
heart development GO:0007507 72 0.013
response to glucose GO:0009749 136 0.013
transmembrane transport GO:0055085 412 0.013
isoquinoline alkaloid metabolic process GO:0033076 2 0.013
catechol containing compound metabolic process GO:0009712 19 0.013
Rat
one carbon compound transport GO:0019755 5 0.013
anatomical structure morphogenesis GO:0009653 298 0.012
immune system process GO:0002376 204 0.012
glial cell differentiation GO:0010001 65 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of insulin secretion GO:0050796 65 0.012
sensory perception of smell GO:0007608 5 0.012
phenol containing compound biosynthetic process GO:0046189 9 0.012
Rat
cellular response to nutrient levels GO:0031669 60 0.012
fatty acid catabolic process GO:0009062 26 0.012
sensory perception GO:0007600 101 0.012
response to alkaloid GO:0043279 132 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
regulation of blood circulation GO:1903522 110 0.012
xenobiotic catabolic process GO:0042178 7 0.012
fructose 2 6 bisphosphate metabolic process GO:0006003 2 0.012
circadian rhythm GO:0007623 88 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
peptide secretion GO:0002790 86 0.012
negative regulation of cell differentiation GO:0045596 99 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
alpha amino acid catabolic process GO:1901606 20 0.011
neurotransmitter uptake GO:0001504 3 0.011
intracellular protein transport GO:0006886 79 0.011
spermatogenesis GO:0007283 99 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
pyridine nucleotide metabolic process GO:0019362 28 0.011
oxidative demethylation GO:0070989 2 0.011
response to genistein GO:0033595 4 0.011
toxin catabolic process GO:0009407 1 0.011
response to fatty acid GO:0070542 65 0.011
male gonad development GO:0008584 59 0.010
protein complex subunit organization GO:0071822 302 0.010
lipid oxidation GO:0034440 30 0.010
negative regulation of protein import into nucleus translocation GO:0033159 1 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
intracellular transport GO:0046907 185 0.010
regulation of system process GO:0044057 208 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
catecholamine metabolic process GO:0006584 19 0.010
Rat
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.010
catecholamine biosynthetic process GO:0042423 9 0.010
Rat
protein transport GO:0015031 132 0.010
response to oxidative stress GO:0006979 186 0.010
protein targeting GO:0006605 61 0.010
cellular alcohol biosynthetic process GO:0044108 2 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
lipid catabolic process GO:0016042 46 0.010
protein localization GO:0008104 191 0.010
pyrimidine nucleobase catabolic process GO:0006208 3 0.010

Cyp2e1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.040
nutrition disease DOID:374 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
renal tubular transport disease DOID:447 0 0.015
kidney disease DOID:557 0 0.015
disease of anatomical entity DOID:7 0 0.015
urinary system disease DOID:18 0 0.015
long qt syndrome DOID:2843 0 0.012