Rattus norvegicus

0 known processes

Gen1

Gen homolog 1, endonuclease (Drosophila)

(Aliases: RGD1559792)

Gen1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.112
carboxylic acid metabolic process GO:0019752 289 0.098
organic acid metabolic process GO:0006082 292 0.065
cellular amino acid metabolic process GO:0006520 107 0.044
lipid metabolic process GO:0006629 283 0.039
regulation of rna metabolic process GO:0051252 391 0.039
response to external biotic stimulus GO:0043207 221 0.038
regulation of cell development GO:0060284 263 0.038
regulation of neurogenesis GO:0050767 247 0.037
monocarboxylic acid metabolic process GO:0032787 152 0.037
organic anion transport GO:0015711 132 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.037
regulation of nervous system development GO:0051960 264 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
positive regulation of cell proliferation GO:0008284 249 0.034
cellular response to oxygen containing compound GO:1901701 386 0.033
nitrogen compound transport GO:0071705 229 0.032
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.032
cellular amine metabolic process GO:0044106 38 0.030
positive regulation of cell development GO:0010720 176 0.029
positive regulation of developmental process GO:0051094 283 0.029
programmed cell death GO:0012501 392 0.028
response to bacterium GO:0009617 200 0.028
cellular component assembly GO:0022607 360 0.028
secretion by cell GO:0032940 248 0.028
rna metabolic process GO:0016070 406 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of rna biosynthetic process GO:2001141 381 0.027
catabolic process GO:0009056 351 0.027
rna biosynthetic process GO:0032774 380 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
regulation of catalytic activity GO:0050790 304 0.027
cellular component biogenesis GO:0044085 368 0.026
regulation of neuron differentiation GO:0045664 208 0.026
neuron projection development GO:0031175 273 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
regulation of programmed cell death GO:0043067 341 0.025
metal ion homeostasis GO:0055065 186 0.025
cellular ketone metabolic process GO:0042180 51 0.025
negative regulation of metabolic process GO:0009892 331 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
apoptotic process GO:0006915 381 0.024
intracellular signal transduction GO:0035556 314 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
response to biotic stimulus GO:0009607 226 0.023
negative regulation of innate immune response GO:0045824 4 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
cellular response to stress GO:0033554 269 0.023
response to insulin GO:0032868 133 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.022
response to peptide hormone GO:0043434 278 0.022
amide transport GO:0042886 105 0.022
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.022
regulation of transcription dna templated GO:0006355 374 0.022
protein complex subunit organization GO:0071822 302 0.022
cation transport GO:0006812 382 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
organic substance catabolic process GO:1901575 316 0.021
response to inorganic substance GO:0010035 377 0.021
positive regulation of molecular function GO:0044093 230 0.021
chemical homeostasis GO:0048878 292 0.021
response to oxidative stress GO:0006979 186 0.021
neuron differentiation GO:0030182 368 0.020
protein phosphorylation GO:0006468 345 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
oxidation reduction process GO:0055114 304 0.020
protein oligomerization GO:0051259 191 0.020
ras protein signal transduction GO:0007265 29 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
response to ethanol GO:0045471 162 0.020
carboxylic acid transport GO:0046942 115 0.020
response to other organism GO:0051707 220 0.020
macromolecular complex assembly GO:0065003 273 0.020
organic acid transport GO:0015849 116 0.020
cellular component movement GO:0006928 248 0.019
locomotion GO:0040011 237 0.019
amine metabolic process GO:0009308 38 0.019
protein complex assembly GO:0006461 263 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
transcription dna templated GO:0006351 377 0.019
positive regulation of nervous system development GO:0051962 178 0.019
response to nutrient levels GO:0031667 370 0.019
protein complex biogenesis GO:0070271 263 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
metal ion transport GO:0030001 289 0.019
regulation of cell proliferation GO:0042127 359 0.018
nucleic acid templated transcription GO:0097659 379 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
homeostatic process GO:0042592 331 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
response to ketone GO:1901654 182 0.018
response to oxygen levels GO:0070482 265 0.018
cellular chemical homeostasis GO:0055082 247 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of signal transduction GO:0009966 318 0.018
cellular homeostasis GO:0019725 252 0.017
protein heterooligomerization GO:0051291 89 0.017
single organism biosynthetic process GO:0044711 342 0.017
regulation of cellular component organization GO:0051128 368 0.017
response to acid chemical GO:0001101 222 0.017
response to metal ion GO:0010038 253 0.017
regulation of apoptotic process GO:0042981 335 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
cell migration GO:0016477 197 0.017
anion transport GO:0006820 178 0.017
single organism catabolic process GO:0044712 283 0.017
fatty acid metabolic process GO:0006631 99 0.017
reproductive process GO:0022414 372 0.017
response to monosaccharide GO:0034284 159 0.017
regulation of cell differentiation GO:0045595 320 0.017
brain development GO:0007420 247 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
positive regulation of signaling GO:0023056 270 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of signal transduction GO:0009967 175 0.016
response to carbohydrate GO:0009743 183 0.016
calcium ion homeostasis GO:0055074 162 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of gene expression GO:0010629 199 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
defense response GO:0006952 194 0.016
cofactor metabolic process GO:0051186 95 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
regulation of neuron projection development GO:0010975 161 0.016
response to corticosteroid GO:0031960 235 0.016
cell projection organization GO:0030030 302 0.015
positive regulation of cell communication GO:0010647 271 0.015
response to hypoxia GO:0001666 231 0.015
positive regulation of gene expression GO:0010628 244 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
regulation of protein metabolic process GO:0051246 289 0.015
aging GO:0007568 241 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
regulation of cell projection organization GO:0031344 175 0.015
regulation of protein modification process GO:0031399 194 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
neuron development GO:0048666 286 0.015
multi organism reproductive process GO:0044703 262 0.015
secretion GO:0046903 307 0.015
cellular catabolic process GO:0044248 295 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
central nervous system development GO:0007417 311 0.015
response to decreased oxygen levels GO:0036293 237 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
regulation of phosphorylation GO:0042325 248 0.014
purine containing compound metabolic process GO:0072521 253 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
negative regulation of response to tumor cell GO:0002835 2 0.014
peptide transport GO:0015833 97 0.014
cell motility GO:0048870 202 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
positive regulation of cell death GO:0010942 184 0.014
response to estrogen GO:0043627 232 0.014
negative regulation of transport GO:0051051 136 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
regulation of locomotion GO:0040012 148 0.014
cellular cation homeostasis GO:0030003 180 0.014
cellular ion homeostasis GO:0006873 184 0.014
regulation of molecular function GO:0065009 398 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of immune response to tumor cell GO:0002837 3 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
immune response GO:0006955 104 0.013
nucleotide metabolic process GO:0009117 279 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
neuron death GO:0070997 127 0.013
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.013
single organism behavior GO:0044708 130 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
peptide hormone secretion GO:0030072 84 0.012
leukocyte cell cell adhesion GO:0007159 4 0.012
synaptic transmission GO:0007268 235 0.012
positive regulation of protein modification process GO:0031401 142 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.012
localization of cell GO:0051674 202 0.012
carboxylic acid catabolic process GO:0046395 49 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of defense response GO:0031347 68 0.012
innate immune response GO:0045087 35 0.012
mapk cascade GO:0000165 140 0.012
response to hexose GO:0009746 144 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of neuron death GO:1901214 115 0.012
signal release GO:0023061 145 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
cation homeostasis GO:0055080 195 0.012
cell activation GO:0001775 97 0.012
salivary gland development GO:0007431 3 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
response to growth factor GO:0070848 189 0.012
circulatory system process GO:0003013 183 0.012
negative regulation of neuron death GO:1901215 69 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
ion homeostasis GO:0050801 212 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
hormone metabolic process GO:0042445 69 0.012
positive regulation of catalytic activity GO:0043085 184 0.011
lipid storage GO:0019915 1 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
developmental process involved in reproduction GO:0003006 159 0.011
molting cycle process GO:0022404 2 0.011
spindle organization GO:0007051 2 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
cell cell signaling GO:0007267 335 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
immunoglobulin mediated immune response GO:0016064 4 0.011
immune system process GO:0002376 204 0.011
sulfur compound metabolic process GO:0006790 70 0.011
regulation of response to tumor cell GO:0002834 3 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
negative regulation of cell death GO:0060548 229 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of blood pressure GO:0008217 83 0.011
heart morphogenesis GO:0003007 3 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
response to glucose GO:0009749 136 0.011
regulation of membrane potential GO:0042391 110 0.011
insulin secretion GO:0030073 69 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to radiation GO:0009314 137 0.011
response to lipopolysaccharide GO:0032496 191 0.011
head development GO:0060322 247 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
response to reactive oxygen species GO:0000302 120 0.010
hair cycle GO:0042633 3 0.010
behavior GO:0007610 205 0.010
cellular response to external stimulus GO:0071496 118 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
negative regulation of immune response to tumor cell GO:0002838 2 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
peptidyl amino acid modification GO:0018193 126 0.010
regeneration GO:0031099 163 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of protein kinase activity GO:0045859 105 0.010
macromolecule localization GO:0033036 252 0.010
response to nutrient GO:0007584 248 0.010
negative regulation of cell communication GO:0010648 158 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
regulation of cellular localization GO:0060341 263 0.010
response to mechanical stimulus GO:0009612 134 0.010
response to alkaloid GO:0043279 132 0.010
response to estradiol GO:0032355 164 0.010
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.010
hormone secretion GO:0046879 115 0.010
lipid localization GO:0010876 62 0.010
cell type specific apoptotic process GO:0097285 134 0.010
response to molecule of bacterial origin GO:0002237 194 0.010

Gen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.012
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011