Rattus norvegicus

167 known processes

Pde2a

phosphodiesterase 2A, cGMP-stimulated

(Aliases: Pde2a2,Pde2)

Pde2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.457
regulation of signal transduction GO:0009966 318 0.241
regulation of phosphate metabolic process GO:0019220 349 0.205
positive regulation of multicellular organismal process GO:0051240 387 0.187
Rat
ribonucleotide metabolic process GO:0009259 231 0.184
regulation of multicellular organismal development GO:2000026 376 0.175
macromolecule localization GO:0033036 252 0.164
regulation of cellular component organization GO:0051128 368 0.163
purine containing compound metabolic process GO:0072521 253 0.142
neuron differentiation GO:0030182 368 0.133
purine nucleotide metabolic process GO:0006163 229 0.129
regulation of molecular function GO:0065009 398 0.122
regulation of cell development GO:0060284 263 0.122
programmed cell death GO:0012501 392 0.119
Rat
regulation of intracellular signal transduction GO:1902531 218 0.116
regulation of phosphorus metabolic process GO:0051174 349 0.114
localization of cell GO:0051674 202 0.110
organophosphate metabolic process GO:0019637 370 0.109
cellular macromolecule localization GO:0070727 122 0.108
regulation of nervous system development GO:0051960 264 0.107
purine ribonucleotide metabolic process GO:0009150 227 0.106
regulation of catalytic activity GO:0050790 304 0.105
neuron projection development GO:0031175 273 0.103
response to extracellular stimulus GO:0009991 380 0.102
protein phosphorylation GO:0006468 345 0.099
nucleotide metabolic process GO:0009117 279 0.098
g protein coupled receptor signaling pathway GO:0007186 242 0.098
positive regulation of phosphorus metabolic process GO:0010562 262 0.098
nucleoside phosphate metabolic process GO:0006753 283 0.096
positive regulation of molecular function GO:0044093 230 0.092
nucleobase containing small molecule metabolic process GO:0055086 316 0.089
organic substance catabolic process GO:1901575 316 0.088
central nervous system development GO:0007417 311 0.088
ribose phosphate metabolic process GO:0019693 235 0.087
positive regulation of developmental process GO:0051094 283 0.086
lipid metabolic process GO:0006629 283 0.086
homeostatic process GO:0042592 331 0.086
carbohydrate derivative metabolic process GO:1901135 346 0.086
ribonucleotide catabolic process GO:0009261 136 0.083
purine ribonucleotide catabolic process GO:0009154 136 0.083
positive regulation of phosphate metabolic process GO:0045937 262 0.082
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.081
regulation of neurogenesis GO:0050767 247 0.081
cellular catabolic process GO:0044248 295 0.080
small gtpase mediated signal transduction GO:0007264 36 0.079
locomotion GO:0040011 237 0.078
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.078
cell projection organization GO:0030030 302 0.078
regulation of cell differentiation GO:0045595 320 0.078
catabolic process GO:0009056 351 0.077
single organism organelle organization GO:1902589 180 0.077
cellular protein localization GO:0034613 122 0.077
regulation of nucleic acid templated transcription GO:1903506 380 0.076
Human
nucleoside phosphate catabolic process GO:1901292 140 0.074
aromatic compound catabolic process GO:0019439 168 0.073
organonitrogen compound catabolic process GO:1901565 179 0.073
cell morphogenesis GO:0000902 142 0.073
organic acid metabolic process GO:0006082 292 0.072
protein localization GO:0008104 191 0.071
carboxylic acid metabolic process GO:0019752 289 0.070
apoptotic process GO:0006915 381 0.069
Rat
purine containing compound catabolic process GO:0072523 138 0.068
cellular lipid metabolic process GO:0044255 208 0.068
synaptic transmission GO:0007268 235 0.067
transcription dna templated GO:0006351 377 0.066
Human
cell migration GO:0016477 197 0.066
regulation of cellular component movement GO:0051270 150 0.065
regulation of cellular localization GO:0060341 263 0.064
Human
organophosphate catabolic process GO:0046434 148 0.064
regulation of nucleotide metabolic process GO:0006140 117 0.064
ribonucleoside metabolic process GO:0009119 174 0.063
circulatory system process GO:0003013 183 0.063
Human Rat
single organism catabolic process GO:0044712 283 0.062
cellular component biogenesis GO:0044085 368 0.062
regulation of locomotion GO:0040012 148 0.062
organelle organization GO:0006996 266 0.062
transmembrane transport GO:0055085 412 0.061
cell projection morphogenesis GO:0048858 123 0.061
nucleoside triphosphate catabolic process GO:0009143 123 0.060
neuron development GO:0048666 286 0.060
chemical homeostasis GO:0048878 292 0.060
positive regulation of biosynthetic process GO:0009891 319 0.059
cellular amino acid metabolic process GO:0006520 107 0.059
nucleobase containing compound catabolic process GO:0034655 152 0.059
brain development GO:0007420 247 0.058
negative regulation of developmental process GO:0051093 125 0.058
ribonucleoside catabolic process GO:0042454 126 0.058
nucleoside triphosphate metabolic process GO:0009141 144 0.058
nucleotide catabolic process GO:0009166 139 0.057
negative regulation of cell communication GO:0010648 158 0.057
positive regulation of protein phosphorylation GO:0001934 135 0.057
purine nucleoside catabolic process GO:0006152 124 0.056
purine ribonucleoside catabolic process GO:0046130 124 0.056
oxoacid metabolic process GO:0043436 290 0.056
positive regulation of transport GO:0051050 245 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
cellular component movement GO:0006928 248 0.055
nucleoside metabolic process GO:0009116 179 0.054
head development GO:0060322 247 0.054
response to nutrient levels GO:0031667 370 0.054
purine nucleoside triphosphate catabolic process GO:0009146 122 0.053
positive regulation of response to stimulus GO:0048584 285 0.053
Mouse Rat
organic cyclic compound catabolic process GO:1901361 175 0.053
cell motility GO:0048870 202 0.052
negative regulation of multicellular organismal process GO:0051241 203 0.052
regulation of apoptotic process GO:0042981 335 0.051
Rat
forebrain development GO:0030900 98 0.051
carbohydrate derivative catabolic process GO:1901136 147 0.051
response to nutrient GO:0007584 248 0.051
reproductive process GO:0022414 372 0.051
protein complex biogenesis GO:0070271 263 0.050
rna metabolic process GO:0016070 406 0.049
Human
glycosyl compound metabolic process GO:1901657 182 0.049
regulation of rna metabolic process GO:0051252 391 0.049
Human
regulation of cell motility GO:2000145 131 0.049
cellular response to stress GO:0033554 269 0.049
regulation of rna biosynthetic process GO:2001141 381 0.049
Human
rna biosynthetic process GO:0032774 380 0.048
Human
ribonucleoside triphosphate catabolic process GO:0009203 122 0.048
regulation of phosphorylation GO:0042325 248 0.048
regulation of purine nucleotide metabolic process GO:1900542 115 0.048
purine nucleoside metabolic process GO:0042278 169 0.048
negative regulation of metabolic process GO:0009892 331 0.047
ras protein signal transduction GO:0007265 29 0.047
amine metabolic process GO:0009308 38 0.046
neuron projection morphogenesis GO:0048812 122 0.046
positive regulation of catalytic activity GO:0043085 184 0.046
immune system process GO:0002376 204 0.046
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.045
regulation of neuron differentiation GO:0045664 208 0.045
cellular component morphogenesis GO:0032989 155 0.044
regulation of neuron projection development GO:0010975 161 0.044
negative regulation of response to stimulus GO:0048585 155 0.044
response to oxygen levels GO:0070482 265 0.044
Rat
regulation of catabolic process GO:0009894 113 0.044
vesicle mediated transport GO:0016192 181 0.044
response to metal ion GO:0010038 253 0.044
regulation of cell projection organization GO:0031344 175 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.043
positive regulation of cellular component organization GO:0051130 200 0.043
response to carbohydrate GO:0009743 183 0.042
nucleoside catabolic process GO:0009164 126 0.042
response to purine containing compound GO:0014074 126 0.042
Human
single organism behavior GO:0044708 130 0.041
Rat
regulation of small gtpase mediated signal transduction GO:0051056 48 0.041
single organism biosynthetic process GO:0044711 342 0.041
cellular amine metabolic process GO:0044106 38 0.041
behavior GO:0007610 205 0.041
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.040
reproduction GO:0000003 245 0.040
regulation of protein phosphorylation GO:0001932 183 0.040
regulation of anatomical structure size GO:0090066 135 0.040
Rat
macromolecular complex assembly GO:0065003 273 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
purine ribonucleoside metabolic process GO:0046128 168 0.039
positive regulation of phosphorylation GO:0042327 177 0.039
single organism membrane organization GO:0044802 74 0.039
positive regulation of signaling GO:0023056 270 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
positive regulation of cell communication GO:0010647 271 0.038
nucleic acid templated transcription GO:0097659 379 0.038
Human
intracellular transport GO:0046907 185 0.037
organic hydroxy compound metabolic process GO:1901615 115 0.037
protein complex subunit organization GO:0071822 302 0.037
purine nucleotide catabolic process GO:0006195 136 0.037
regulation of cell migration GO:0030334 128 0.037
glycosyl compound catabolic process GO:1901658 126 0.037
cation homeostasis GO:0055080 195 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
cell morphogenesis involved in differentiation GO:0000904 119 0.037
positive regulation of nervous system development GO:0051962 178 0.037
ion transmembrane transport GO:0034220 365 0.036
negative regulation of cell death GO:0060548 229 0.036
cellular component assembly GO:0022607 360 0.036
protein transport GO:0015031 132 0.036
positive regulation of cell differentiation GO:0045597 217 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
protein complex assembly GO:0006461 263 0.035
regulation of secretion by cell GO:1903530 208 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
heterocycle catabolic process GO:0046700 167 0.034
positive regulation of neurogenesis GO:0050769 165 0.034
cellular homeostasis GO:0019725 252 0.034
regulation of protein metabolic process GO:0051246 289 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.033
single organism reproductive process GO:0044702 297 0.033
membrane organization GO:0061024 94 0.033
positive regulation of gene expression GO:0010628 244 0.033
Mouse
cation transport GO:0006812 382 0.032
regulation of protein modification process GO:0031399 194 0.032
positive regulation of hydrolase activity GO:0051345 86 0.032
regulation of ion transport GO:0043269 245 0.032
negative regulation of gene expression GO:0010629 199 0.032
Human
regulation of gtpase activity GO:0043087 57 0.032
multi organism reproductive process GO:0044703 262 0.032
cellular ion homeostasis GO:0006873 184 0.031
cellular ketone metabolic process GO:0042180 51 0.031
immune response GO:0006955 104 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
nitrogen compound transport GO:0071705 229 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.030
defecation GO:0030421 1 0.030
regulation of programmed cell death GO:0043067 341 0.030
Rat
cation transmembrane transport GO:0098655 263 0.030
regulation of membrane potential GO:0042391 110 0.030
innate immune response GO:0045087 35 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
positive regulation of gtpase activity GO:0043547 47 0.030
cell part morphogenesis GO:0032990 123 0.029
growth GO:0040007 165 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
gtp catabolic process GO:0006184 71 0.028
guanosine containing compound metabolic process GO:1901068 74 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
cardiovascular system development GO:0072358 134 0.028
regulation of cell proliferation GO:0042127 359 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
Human
neurological system process GO:0050877 219 0.028
Rat
regulation of purine nucleotide catabolic process GO:0033121 65 0.028
response to peptide GO:1901652 292 0.028
positive regulation of nucleotide metabolic process GO:0045981 91 0.028
positive regulation of cell development GO:0010720 176 0.028
negative regulation of cell development GO:0010721 82 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
response to acid chemical GO:0001101 222 0.027
negative regulation of transport GO:0051051 136 0.027
Human
regulation of hydrolase activity GO:0051336 143 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of response to stress GO:0080134 126 0.027
Mouse Rat
regulation of organelle organization GO:0033043 80 0.026
negative regulation of signaling GO:0023057 157 0.026
multicellular organism reproduction GO:0032504 233 0.026
regulation of nucleotide catabolic process GO:0030811 65 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
Human
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
Human
protein oligomerization GO:0051259 191 0.026
response to peptide hormone GO:0043434 278 0.026
telencephalon development GO:0021537 62 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
regulation of synaptic transmission GO:0050804 141 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
establishment of protein localization GO:0045184 141 0.025
positive regulation of protein modification process GO:0031401 142 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
positive regulation of cell migration GO:0030335 96 0.025
tissue development GO:0009888 252 0.025
cell cell signaling GO:0007267 335 0.025
cell cycle GO:0007049 101 0.025
cellular response to lipid GO:0071396 201 0.025
Mouse
guanosine containing compound catabolic process GO:1901069 71 0.024
positive regulation of ras gtpase activity GO:0032320 28 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
positive regulation of cellular component movement GO:0051272 102 0.024
locomotory exploration behavior GO:0035641 1 0.024
mapk cascade GO:0000165 140 0.024
tube formation GO:0035148 3 0.024
memory GO:0007613 54 0.024
Rat
positive regulation of secretion GO:0051047 140 0.024
single organism cellular localization GO:1902580 102 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Human
negative regulation of apoptotic process GO:0043066 181 0.023
positive regulation of neuron differentiation GO:0045666 126 0.023
cytoskeleton organization GO:0007010 111 0.023
ribonucleotide biosynthetic process GO:0009260 85 0.023
regulation of ras gtpase activity GO:0032318 32 0.023
regulation of defense response GO:0031347 68 0.022
Mouse Rat
regulation of transcription dna templated GO:0006355 374 0.022
Human
actin filament based process GO:0030029 86 0.022
response to lipopolysaccharide GO:0032496 191 0.022
Mouse Rat
peptidyl amino acid modification GO:0018193 126 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
secretion GO:0046903 307 0.022
positive regulation of cell projection organization GO:0031346 111 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
response to bacterium GO:0009617 200 0.022
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
positive regulation of gtp catabolic process GO:0033126 48 0.022
response to hypoxia GO:0001666 231 0.022
Rat
negative regulation of programmed cell death GO:0043069 183 0.022
response to organophosphorus GO:0046683 102 0.022
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
Human
response to external biotic stimulus GO:0043207 221 0.021
Mouse Rat
multi multicellular organism process GO:0044706 138 0.021
regulation of growth GO:0040008 105 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.021
regulation of lipid metabolic process GO:0019216 68 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of secretion GO:0051046 224 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.021
cognition GO:0050890 92 0.021
Rat
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.021
response to inorganic substance GO:0010035 377 0.021
adult locomotory behavior GO:0008344 4 0.021
small molecule biosynthetic process GO:0044283 124 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
gtp metabolic process GO:0046039 72 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
Human Mouse
negative regulation of neuron differentiation GO:0045665 62 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
regulation of transferase activity GO:0051338 123 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
positive regulation of ion transport GO:0043270 94 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
protein autophosphorylation GO:0046777 66 0.020
response to cytokine GO:0034097 215 0.020
Human
regulation of cell cycle GO:0051726 73 0.020
anatomical structure formation involved in morphogenesis GO:0048646 83 0.020
calcium ion homeostasis GO:0055074 162 0.020
learning or memory GO:0007611 90 0.019
Rat
response to other organism GO:0051707 220 0.019
Mouse Rat
learning GO:0007612 33 0.019
defense response GO:0006952 194 0.019
Mouse Rat
peptide hormone secretion GO:0030072 84 0.019
response to camp GO:0051591 91 0.019
regulation of kinase activity GO:0043549 117 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
alcohol metabolic process GO:0006066 77 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
regulation of immune system process GO:0002682 123 0.019
response to estrogen GO:0043627 232 0.019
positive regulation of cell motility GO:2000147 97 0.019
regulation of cell morphogenesis GO:0022604 77 0.019
negative regulation of biosynthetic process GO:0009890 168 0.018
response to glucocorticoid GO:0051384 223 0.018
response to decreased oxygen levels GO:0036293 237 0.018
Rat
rhythmic process GO:0048511 156 0.018
neuron neuron synaptic transmission GO:0007270 60 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
response to toxic substance GO:0009636 133 0.018
rho protein signal transduction GO:0007266 11 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.018
blood circulation GO:0008015 183 0.018
Human Rat
wound healing GO:0042060 122 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
neuron death GO:0070997 127 0.018
response to insulin GO:0032868 133 0.018
response to monosaccharide GO:0034284 159 0.018
response to reactive oxygen species GO:0000302 120 0.018
response to light stimulus GO:0009416 52 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
Rat
regulation of dendrite development GO:0050773 59 0.018
ion homeostasis GO:0050801 212 0.017
axis specification GO:0009798 4 0.017
hormone transport GO:0009914 121 0.017
anion transport GO:0006820 178 0.017
glycerolipid metabolic process GO:0046486 67 0.017
epithelium development GO:0060429 96 0.017
actin cytoskeleton organization GO:0030036 73 0.017
positive regulation of immune system process GO:0002684 90 0.017
regulation of synapse maturation GO:0090128 2 0.017
multicellular organism growth GO:0035264 1 0.017
regeneration GO:0031099 163 0.017
sexual reproduction GO:0019953 148 0.017
vasculogenesis GO:0001570 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
double strand break repair GO:0006302 1 0.017
regulation of behavior GO:0050795 61 0.017
cyclic purine nucleotide metabolic process GO:0052652 62 0.017
positive regulation of catabolic process GO:0009896 78 0.017
positive regulation of synapse maturation GO:0090129 2 0.017
positive regulation of synaptic transmission GO:0050806 62 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
axonogenesis GO:0007409 71 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
negative regulation of nervous system development GO:0051961 79 0.016
relaxation of muscle GO:0090075 4 0.016
organic acid transport GO:0015849 116 0.016
neuromuscular process GO:0050905 2 0.016
heart morphogenesis GO:0003007 3 0.016
cell fate determination GO:0001709 2 0.016
regulation of gtp catabolic process GO:0033124 58 0.016
gamete generation GO:0007276 124 0.016
signal release GO:0023061 145 0.016
positive regulation of receptor activity GO:2000273 4 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
Human
cyclic nucleotide metabolic process GO:0009187 80 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
taxis GO:0042330 67 0.016
positive regulation of transferase activity GO:0051347 81 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
cell growth GO:0016049 104 0.015
response to glucose GO:0009749 136 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of cell death GO:0010942 184 0.015
Rat
response to molecule of bacterial origin GO:0002237 194 0.015
Mouse Rat
secretion by cell GO:0032940 248 0.015
peptide secretion GO:0002790 86 0.015
endocytosis GO:0006897 84 0.015
anterior posterior pattern specification GO:0009952 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
neuron apoptotic process GO:0051402 88 0.015
response to corticosteroid GO:0031960 235 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
carbohydrate metabolic process GO:0005975 130 0.015
sensory perception GO:0007600 101 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
Rat
regulation of hormone levels GO:0010817 187 0.015
response to radiation GO:0009314 137 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
Human
regulation of homeostatic process GO:0032844 101 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
protein targeting GO:0006605 61 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
positive regulation of kinase activity GO:0033674 77 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
Human
developmental growth GO:0048589 100 0.015
axon development GO:0061564 96 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
response to wounding GO:0009611 254 0.014
Mouse Rat
cell cycle checkpoint GO:0000075 2 0.014
proteolysis GO:0006508 175 0.014
cellular cation homeostasis GO:0030003 180 0.014
positive regulation of locomotion GO:0040017 102 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of protein localization GO:0032880 81 0.014
Human
cellular carbohydrate metabolic process GO:0044262 72 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
positive regulation of nucleotide catabolic process GO:0030813 53 0.014
phospholipid metabolic process GO:0006644 61 0.014
regulation of receptor activity GO:0010469 29 0.014
regulation of hormone secretion GO:0046883 106 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
muscle system process GO:0003012 115 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
cytoplasmic transport GO:0016482 115 0.014
dendrite development GO:0016358 72 0.014
sensory organ development GO:0007423 74 0.014
spindle organization GO:0007051 2 0.014
cell type specific apoptotic process GO:0097285 134 0.014
divalent inorganic cation transport GO:0072511 134 0.013
regulation of ras protein signal transduction GO:0046578 45 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
cellular chemical homeostasis GO:0055082 247 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to oxidative stress GO:0006979 186 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
maintenance of location GO:0051235 17 0.013
ameboidal type cell migration GO:0001667 26 0.013
negative regulation of innate immune response GO:0045824 4 0.013
dna metabolic process GO:0006259 96 0.013
regulation of body fluid levels GO:0050878 90 0.013
regulation of peptide secretion GO:0002791 82 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
carboxylic acid transport GO:0046942 115 0.013
aging GO:0007568 241 0.013
spermatogenesis GO:0007283 99 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
response to hexose GO:0009746 144 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of angiogenesis GO:0045765 39 0.013
exploration behavior GO:0035640 1 0.013
response to calcium ion GO:0051592 59 0.013
calcium ion transport GO:0006816 131 0.013
response to biotic stimulus GO:0009607 226 0.013
Mouse Rat
cell cycle process GO:0022402 57 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to growth factor GO:0070848 189 0.012
Human
male gamete generation GO:0048232 99 0.012
muscle contraction GO:0006936 88 0.012
reproductive structure development GO:0048608 128 0.012
regulation of neuron death GO:1901214 115 0.012
positive regulation of angiogenesis GO:0045766 28 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
positive regulation of rho gtpase activity GO:0032321 13 0.012
regulation of protein kinase activity GO:0045859 105 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
Human
regulation of cellular component biogenesis GO:0044087 86 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012

Pde2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
central nervous system disease DOID:331 0 0.016
disease of cellular proliferation DOID:14566 0 0.014