Rattus norvegicus

89 known processes

Psmc5

proteasome (prosome, macropain) 26S subunit, ATPase, 5

(Aliases: Sug1)

Psmc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription initiation from rna polymerase ii promoter GO:0006367 3 0.978
Yeast
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 3 0.897
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.794
atp catabolic process GO:0006200 54 0.756
dna templated transcription initiation GO:0006352 4 0.709
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 55 0.659
ribonucleoside triphosphate catabolic process GO:0009203 122 0.615
purine nucleoside triphosphate catabolic process GO:0009146 122 0.588
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 3 0.537
Yeast
organophosphate catabolic process GO:0046434 148 0.502
ribonucleoside triphosphate metabolic process GO:0009199 141 0.486
nucleoside phosphate catabolic process GO:1901292 140 0.452
nucleoside monophosphate catabolic process GO:0009125 56 0.448
purine nucleoside catabolic process GO:0006152 124 0.417
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.405
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.346
atp metabolic process GO:0046034 72 0.321
carbohydrate derivative catabolic process GO:1901136 147 0.307
cellular catabolic process GO:0044248 295 0.294
purine nucleotide metabolic process GO:0006163 229 0.274
macromolecule catabolic process GO:0009057 58 0.267
Human Yeast
purine ribonucleotide catabolic process GO:0009154 136 0.264
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.261
dna templated transcriptional preinitiation complex assembly GO:0070897 3 0.249
Yeast
ribonucleotide catabolic process GO:0009261 136 0.243
protein localization GO:0008104 191 0.240
nucleobase containing compound catabolic process GO:0034655 152 0.235
cellular response to stress GO:0033554 269 0.227
Yeast Fly
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 3 0.226
Yeast
nucleoside triphosphate metabolic process GO:0009141 144 0.222
purine containing compound metabolic process GO:0072521 253 0.218
purine nucleoside monophosphate metabolic process GO:0009126 84 0.211
rna metabolic process GO:0016070 406 0.209
Yeast Mouse
ribonucleoside catabolic process GO:0042454 126 0.207
organic cyclic compound catabolic process GO:1901361 175 0.202
aromatic compound catabolic process GO:0019439 168 0.201
heterocycle catabolic process GO:0046700 167 0.200
purine ribonucleotide metabolic process GO:0009150 227 0.197
purine ribonucleoside catabolic process GO:0046130 124 0.196
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.191
cellular macromolecule catabolic process GO:0044265 29 0.191
Human Yeast
transcription dna templated GO:0006351 377 0.190
Yeast Mouse
purine nucleotide catabolic process GO:0006195 136 0.184
purine ribonucleoside metabolic process GO:0046128 168 0.182
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.175
Yeast
modification dependent macromolecule catabolic process GO:0043632 14 0.173
Human Yeast
organic substance catabolic process GO:1901575 316 0.169
regulation of cellular component organization GO:0051128 368 0.162
positive regulation of biosynthetic process GO:0009891 319 0.161
Yeast
positive regulation of dna templated transcription initiation GO:2000144 3 0.161
Yeast
macromolecule localization GO:0033036 252 0.158
nucleotide metabolic process GO:0009117 279 0.153
catabolic process GO:0009056 351 0.151
ribonucleoside metabolic process GO:0009119 174 0.143
nucleoside catabolic process GO:0009164 126 0.140
organophosphate metabolic process GO:0019637 370 0.139
regulation of transcription dna templated GO:0006355 374 0.137
Yeast Mouse
nucleoside triphosphate catabolic process GO:0009143 123 0.134
response to peptide hormone GO:0043434 278 0.133
positive regulation of cellular component organization GO:0051130 200 0.132
purine nucleoside metabolic process GO:0042278 169 0.130
nucleotide catabolic process GO:0009166 139 0.128
carbohydrate derivative metabolic process GO:1901135 346 0.128
cellular nitrogen compound catabolic process GO:0044270 163 0.127
regulation of nucleic acid templated transcription GO:1903506 380 0.125
Yeast Mouse
cellular protein catabolic process GO:0044257 19 0.121
Human Yeast
eye morphogenesis GO:0048592 4 0.119
macromolecular complex subunit organization GO:0043933 339 0.117
Yeast
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.116
Yeast
regulation of rna metabolic process GO:0051252 391 0.113
Yeast Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.110
Human Yeast
nucleoside monophosphate biosynthetic process GO:0009124 28 0.110
nucleoside metabolic process GO:0009116 179 0.109
inorganic ion transmembrane transport GO:0098660 229 0.109
ribonucleotide biosynthetic process GO:0009260 85 0.107
positive regulation of gene expression GO:0010628 244 0.107
Yeast
modification dependent protein catabolic process GO:0019941 14 0.106
Human Yeast
regulation of cellular protein metabolic process GO:0032268 267 0.103
negative regulation of biosynthetic process GO:0009890 168 0.099
Mouse
purine nucleotide biosynthetic process GO:0006164 83 0.093
protein localization to organelle GO:0033365 57 0.089
regulation of cell differentiation GO:0045595 320 0.087
transmembrane transport GO:0055085 412 0.086
mitotic spindle organization GO:0007052 2 0.086
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.084
Mouse
purine containing compound catabolic process GO:0072523 138 0.084
spindle organization GO:0007051 2 0.083
regulation of cell development GO:0060284 263 0.083
glycosyl compound catabolic process GO:1901658 126 0.083
nucleobase containing small molecule metabolic process GO:0055086 316 0.082
purine nucleoside triphosphate metabolic process GO:0009144 141 0.079
cellular component assembly GO:0022607 360 0.079
macromolecular complex assembly GO:0065003 273 0.079
Yeast
transcription from rna polymerase ii promoter GO:0006366 252 0.079
Yeast
single organism cellular localization GO:1902580 102 0.077
double strand break repair GO:0006302 1 0.076
secretion by cell GO:0032940 248 0.076
purine nucleoside biosynthetic process GO:0042451 21 0.075
reproductive process GO:0022414 372 0.073
Worm
positive regulation of protein dephosphorylation GO:0035307 4 0.073
retinal cell programmed cell death GO:0046666 1 0.072
ribose phosphate metabolic process GO:0019693 235 0.072
programmed cell death GO:0012501 392 0.071
multicellular organism reproduction GO:0032504 233 0.069
protein transport GO:0015031 132 0.067
ribonucleoside monophosphate catabolic process GO:0009158 55 0.065
positive regulation of rna metabolic process GO:0051254 203 0.064
Yeast
regulation of cell proliferation GO:0042127 359 0.063
positive regulation of hydrolase activity GO:0051345 86 0.063
organonitrogen compound catabolic process GO:1901565 179 0.063
ribonucleotide metabolic process GO:0009259 231 0.063
regulation of rna biosynthetic process GO:2001141 381 0.063
Yeast Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.062
Yeast
cellular protein localization GO:0034613 122 0.062
sexual reproduction GO:0019953 148 0.062
positive regulation of cellular component biogenesis GO:0044089 55 0.061
negative regulation of multicellular organismal process GO:0051241 203 0.059
amp metabolic process GO:0046033 8 0.058
protein complex assembly GO:0006461 263 0.057
Yeast
regulation of catabolic process GO:0009894 113 0.056
glycosyl compound metabolic process GO:1901657 182 0.056
negative regulation of cell differentiation GO:0045596 99 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.055
Yeast
regulation of stem cell differentiation GO:2000736 2 0.055
regulation of phosphate metabolic process GO:0019220 349 0.054
chromosome segregation GO:0007059 2 0.053
rna biosynthetic process GO:0032774 380 0.053
Yeast Mouse
mitochondrion organization GO:0007005 35 0.053
cation transmembrane transport GO:0098655 263 0.053
secretion GO:0046903 307 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
Yeast
establishment of chromosome localization GO:0051303 1 0.052
cellular macromolecular complex assembly GO:0034622 58 0.052
Yeast
protein complex biogenesis GO:0070271 263 0.050
Yeast
regulation of protein metabolic process GO:0051246 289 0.050
regulation of protein phosphatase type 2a activity GO:0034047 2 0.050
single organism intracellular transport GO:1902582 166 0.049
multicellular organismal reproductive process GO:0048609 233 0.047
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.046
Yeast
membrane fusion GO:0061025 26 0.045
purine ribonucleoside biosynthetic process GO:0046129 21 0.045
positive regulation of catalytic activity GO:0043085 184 0.045
reproduction GO:0000003 245 0.044
Worm
apoptotic process GO:0006915 381 0.044
pyrimidine ribonucleoside triphosphate biosynthetic process GO:0009209 2 0.044
nucleotide biosynthetic process GO:0009165 98 0.043
proteolysis GO:0006508 175 0.042
Human Yeast Fly
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
inorganic cation transmembrane transport GO:0098662 202 0.041
nucleic acid templated transcription GO:0097659 379 0.041
Yeast Mouse
proteasomal protein catabolic process GO:0010498 8 0.041
Human Yeast
growth GO:0040007 165 0.040
protein complex subunit organization GO:0071822 302 0.039
Yeast
calcium ion transport GO:0006816 131 0.038
cation transport GO:0006812 382 0.038
organelle assembly GO:0070925 22 0.037
vesicle mediated transport GO:0016192 181 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.035
intracellular protein transport GO:0006886 79 0.035
multi organism reproductive process GO:0044703 262 0.035
carbohydrate derivative biosynthetic process GO:1901137 124 0.035
golgi organization GO:0007030 17 0.035
ribonucleoside biosynthetic process GO:0042455 25 0.035
establishment of protein localization GO:0045184 141 0.035
regulation of dna templated transcription initiation GO:2000142 3 0.034
Yeast
protein catabolic process GO:0030163 30 0.033
Human Yeast
cellular response to dna damage stimulus GO:0006974 19 0.033
Yeast Fly
protein secretion GO:0009306 34 0.032
osteoblast differentiation GO:0001649 26 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.032
Human Yeast
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
Yeast
male mating behavior GO:0060179 3 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.031
Yeast
organelle organization GO:0006996 266 0.031
Yeast
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.030
purine nucleoside diphosphate metabolic process GO:0009135 9 0.030
regulation of protein catabolic process GO:0042176 16 0.029
cell cycle GO:0007049 101 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
anatomical structure morphogenesis GO:0009653 298 0.028
embryo development GO:0009790 49 0.028
Worm
positive regulation of protein metabolic process GO:0051247 178 0.027
regulation of programmed cell death GO:0043067 341 0.026
cellular response to lipid GO:0071396 201 0.026
ion transmembrane transport GO:0034220 365 0.026
nucleoside monophosphate metabolic process GO:0009123 93 0.026
cellular component biogenesis GO:0044085 368 0.025
purine ribonucleotide biosynthetic process GO:0009152 81 0.025
metal ion transport GO:0030001 289 0.025
regulation of hydrolase activity GO:0051336 143 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
negative regulation of metabolic process GO:0009892 331 0.024
Mouse
aging GO:0007568 241 0.023
regulation of protein modification process GO:0031399 194 0.023
protein prenylation GO:0018342 4 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
regulation of phosphorylation GO:0042325 248 0.022
ras protein signal transduction GO:0007265 29 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
membrane organization GO:0061024 94 0.022
intracellular signal transduction GO:0035556 314 0.021
neuron development GO:0048666 286 0.021
gamete generation GO:0007276 124 0.021
cellular macromolecule localization GO:0070727 122 0.020
mitochondrial transport GO:0006839 19 0.020
negative regulation of signaling GO:0023057 157 0.020
protein phosphorylation GO:0006468 345 0.019
maintenance of location GO:0051235 17 0.019
gtp metabolic process GO:0046039 72 0.019
regulation of transferase activity GO:0051338 123 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
Yeast
nucleoside phosphate metabolic process GO:0006753 283 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.018
regulation of growth GO:0040008 105 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
positive regulation of protein modification process GO:0031401 142 0.018
positive regulation of cell death GO:0010942 184 0.017
intracellular transport GO:0046907 185 0.017
protein processing GO:0016485 68 0.017
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
Mouse
regulation of transmembrane transporter activity GO:0022898 49 0.017
protein maturation GO:0051604 68 0.017
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.017
locomotion GO:0040011 237 0.017
Worm
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of neurogenesis GO:0050767 247 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.016
asymmetric stem cell division GO:0098722 2 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
Yeast
regulation of catalytic activity GO:0050790 304 0.016
cytoskeleton organization GO:0007010 111 0.016
cellular component movement GO:0006928 248 0.016
cardiovascular system development GO:0072358 134 0.016
chromatin assembly or disassembly GO:0006333 1 0.015
cellular protein complex assembly GO:0043623 44 0.015
Yeast
negative regulation of autophagy GO:0010507 1 0.015
purine ribonucleoside diphosphate metabolic process GO:0009179 9 0.015
response to ethanol GO:0045471 162 0.015
single organism reproductive process GO:0044702 297 0.015
Worm
negative regulation of cell proliferation GO:0008285 119 0.015
organ regeneration GO:0031100 101 0.014
positive regulation of cell growth GO:0030307 44 0.014
positive regulation of developmental process GO:0051094 283 0.014
organelle fusion GO:0048284 17 0.014
homeostatic process GO:0042592 331 0.014
cytoplasmic transport GO:0016482 115 0.014
negative regulation of cell communication GO:0010648 158 0.013
organ morphogenesis GO:0009887 75 0.013
chordate embryonic development GO:0043009 18 0.013
divalent metal ion transport GO:0070838 132 0.013
negative regulation of signal transduction GO:0009968 83 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
male gamete generation GO:0048232 99 0.013
development of primary sexual characteristics GO:0045137 107 0.013
Worm
somatic stem cell division GO:0048103 2 0.013
microtubule based process GO:0007017 36 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
Mouse
histone methylation GO:0016571 3 0.013
spermatogenesis GO:0007283 99 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
cell cycle process GO:0022402 57 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of molecular function GO:0044093 230 0.012
Yeast
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
developmental programmed cell death GO:0010623 2 0.012
reproductive structure development GO:0048608 128 0.012
Worm
regulation of signal transduction GO:0009966 318 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
regulation of cell growth GO:0001558 85 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of retinal cell programmed cell death GO:0046668 1 0.012
regulation of proteolysis GO:0030162 66 0.012
response to acid chemical GO:0001101 222 0.012
regulation of response to reactive oxygen species GO:1901031 3 0.011
regulation of epithelial to mesenchymal transition GO:0010717 2 0.011
camp biosynthetic process GO:0006171 47 0.011
associative learning GO:0008306 19 0.011
response to activity GO:0014823 73 0.011
receptor mediated endocytosis GO:0006898 42 0.011
regulation of apoptotic process GO:0042981 335 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.011
endocytosis GO:0006897 84 0.011
nucleoside biosynthetic process GO:0009163 25 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
positive regulation of nervous system development GO:0051962 178 0.011
chemosensory behavior GO:0007635 2 0.011
response to peptide GO:1901652 292 0.011
mitotic cell cycle GO:0000278 49 0.011
regulation of system process GO:0044057 208 0.010
ubiquitin dependent protein catabolic process GO:0006511 14 0.010
Human Yeast
maintenance of protein location in cell GO:0032507 7 0.010
ovulation cycle GO:0042698 67 0.010
mitotic cell cycle process GO:1903047 35 0.010
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
cellular response to external stimulus GO:0071496 118 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
negative regulation of cell death GO:0060548 229 0.010

Psmc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.011