Rattus norvegicus

0 known processes

Wdtc1

WD and tetratricopeptide repeats 1

Wdtc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.110
regulation of signal transduction GO:0009966 318 0.109
regulation of nucleic acid templated transcription GO:1903506 380 0.108
regulation of rna metabolic process GO:0051252 391 0.105
rna biosynthetic process GO:0032774 380 0.100
regulation of rna biosynthetic process GO:2001141 381 0.100
positive regulation of rna biosynthetic process GO:1902680 197 0.097
nucleic acid templated transcription GO:0097659 379 0.090
regulation of transcription dna templated GO:0006355 374 0.081
cellular component assembly GO:0022607 360 0.073
organic substance catabolic process GO:1901575 316 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
neuron differentiation GO:0030182 368 0.072
catabolic process GO:0009056 351 0.071
regulation of molecular function GO:0065009 398 0.067
positive regulation of cellular biosynthetic process GO:0031328 295 0.066
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.062
rna metabolic process GO:0016070 406 0.058
cellular catabolic process GO:0044248 295 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.056
positive regulation of nucleic acid templated transcription GO:1903508 197 0.056
organic acid metabolic process GO:0006082 292 0.055
positive regulation of biosynthetic process GO:0009891 319 0.053
positive regulation of transcription dna templated GO:0045893 197 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.051
regulation of cellular ketone metabolic process GO:0010565 27 0.051
amine metabolic process GO:0009308 38 0.050
positive regulation of response to stimulus GO:0048584 285 0.050
single organism catabolic process GO:0044712 283 0.049
oxoacid metabolic process GO:0043436 290 0.048
apoptotic process GO:0006915 381 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.047
carboxylic acid metabolic process GO:0019752 289 0.046
protein complex assembly GO:0006461 263 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
tissue development GO:0009888 252 0.042
positive regulation of gene expression GO:0010628 244 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.040
regulation of protein metabolic process GO:0051246 289 0.039
cellular component biogenesis GO:0044085 368 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
regulation of cell cycle GO:0051726 73 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
cellular amine metabolic process GO:0044106 38 0.038
ribose phosphate metabolic process GO:0019693 235 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
macromolecular complex subunit organization GO:0043933 339 0.037
cellular ketone metabolic process GO:0042180 51 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
protein phosphorylation GO:0006468 345 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
intracellular signal transduction GO:0035556 314 0.034
blood circulation GO:0008015 183 0.034
positive regulation of rna metabolic process GO:0051254 203 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
positive regulation of signaling GO:0023056 270 0.033
positive regulation of cell communication GO:0010647 271 0.033
programmed cell death GO:0012501 392 0.033
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
single organism biosynthetic process GO:0044711 342 0.032
cell cell signaling GO:0007267 335 0.032
organelle organization GO:0006996 266 0.031
regulation of cellular component organization GO:0051128 368 0.031
response to nutrient levels GO:0031667 370 0.031
positive regulation of signal transduction GO:0009967 175 0.031
neurological system process GO:0050877 219 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
regulation of programmed cell death GO:0043067 341 0.030
macromolecule localization GO:0033036 252 0.030
Fly
protein complex biogenesis GO:0070271 263 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
regulation of system process GO:0044057 208 0.030
chemical homeostasis GO:0048878 292 0.029
cell projection organization GO:0030030 302 0.029
cellular component movement GO:0006928 248 0.029
negative regulation of g0 to g1 transition GO:0070317 1 0.028
central nervous system development GO:0007417 311 0.028
ion transmembrane transport GO:0034220 365 0.028
protein localization GO:0008104 191 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
regulation of cell differentiation GO:0045595 320 0.027
negative regulation of metabolic process GO:0009892 331 0.027
regulation of phosphorylation GO:0042325 248 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
response to inorganic substance GO:0010035 377 0.026
Fly
cell cycle GO:0007049 101 0.026
regulation of cell development GO:0060284 263 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
peptide biosynthetic process GO:0043043 3 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
secretion GO:0046903 307 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
brain development GO:0007420 247 0.024
protein complex subunit organization GO:0071822 302 0.024
cellular response to insulin stimulus GO:0032869 81 0.024
organophosphate metabolic process GO:0019637 370 0.024
response to peptide hormone GO:0043434 278 0.024
positive regulation of transport GO:0051050 245 0.024
action potential GO:0001508 54 0.023
response to acid chemical GO:0001101 222 0.023
Fly
response to biotic stimulus GO:0009607 226 0.023
neuron development GO:0048666 286 0.023
cell growth GO:0016049 104 0.023
anion transport GO:0006820 178 0.022
macromolecule catabolic process GO:0009057 58 0.022
cellular response to stress GO:0033554 269 0.022
cardiovascular system development GO:0072358 134 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of secretion GO:0051046 224 0.021
regulation of protein modification process GO:0031399 194 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
response to cytokine GO:0034097 215 0.021
proteolysis GO:0006508 175 0.021
negative regulation of developmental process GO:0051093 125 0.021
reproductive process GO:0022414 372 0.020
peptidyl amino acid modification GO:0018193 126 0.020
transmembrane transport GO:0055085 412 0.020
response to external biotic stimulus GO:0043207 221 0.020
response to extracellular stimulus GO:0009991 380 0.020
positive regulation of developmental process GO:0051094 283 0.020
regulation of nervous system development GO:0051960 264 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
regulation of blood circulation GO:1903522 110 0.020
cell migration GO:0016477 197 0.019
cell projection morphogenesis GO:0048858 123 0.019
response to other organism GO:0051707 220 0.019
positive regulation of molecular function GO:0044093 230 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
establishment of protein localization GO:0045184 141 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of neurogenesis GO:0050767 247 0.019
protein transport GO:0015031 132 0.019
localization of cell GO:0051674 202 0.019
regulation of g0 to g1 transition GO:0070316 3 0.019
synaptic transmission GO:0007268 235 0.019
membrane repolarization GO:0086009 1 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of neuron projection development GO:0010975 161 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
growth GO:0040007 165 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
heart process GO:0003015 57 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
nucleotide metabolic process GO:0009117 279 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
regulation of catalytic activity GO:0050790 304 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
chromosome segregation GO:0007059 2 0.018
response to hexose GO:0009746 144 0.018
secretion by cell GO:0032940 248 0.018
response to wounding GO:0009611 254 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
locomotion GO:0040011 237 0.018
ion homeostasis GO:0050801 212 0.018
response to metal ion GO:0010038 253 0.018
head development GO:0060322 247 0.018
cation transport GO:0006812 382 0.018
regulation of apoptotic process GO:0042981 335 0.017
regulation of cell proliferation GO:0042127 359 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
vesicle mediated transport GO:0016192 181 0.017
neuron projection development GO:0031175 273 0.017
heterocycle catabolic process GO:0046700 167 0.017
olfactory learning GO:0008355 1 0.017
ras protein signal transduction GO:0007265 29 0.017
immune system process GO:0002376 204 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
endocytosis GO:0006897 84 0.017
response to peptide GO:1901652 292 0.017
multi organism reproductive process GO:0044703 262 0.016
carboxylic acid biosynthetic process GO:0046394 83 0.016
cellular protein catabolic process GO:0044257 19 0.016
response to growth factor GO:0070848 189 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
regulation of neuron differentiation GO:0045664 208 0.016
chemosensory behavior GO:0007635 2 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
circulatory system development GO:0072359 134 0.016
regulation of secretion by cell GO:1903530 208 0.016
regulation of cellular localization GO:0060341 263 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of cell death GO:0010942 184 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
purine containing compound metabolic process GO:0072521 253 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
lipid metabolic process GO:0006629 283 0.016
Fly
multicellular organismal signaling GO:0035637 44 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cell cycle process GO:0022402 57 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
circulatory system process GO:0003013 183 0.015
response to estrogen GO:0043627 232 0.015
regulation of ion transport GO:0043269 245 0.015
organic acid biosynthetic process GO:0016053 83 0.015
cellular response to peptide GO:1901653 133 0.015
adult locomotory behavior GO:0008344 4 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.014
positive regulation of protein modification process GO:0031401 142 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
muscle system process GO:0003012 115 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of secretion GO:0051047 140 0.014
non canonical wnt signaling pathway GO:0035567 3 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
embryonic pattern specification GO:0009880 1 0.014
spindle organization GO:0007051 2 0.014
cellular response to external stimulus GO:0071496 118 0.014
olfactory behavior GO:0042048 2 0.014
cation transmembrane transport GO:0098655 263 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of catabolic process GO:0009894 113 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
metal ion transport GO:0030001 289 0.014
regulation of anatomical structure size GO:0090066 135 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
transmission of nerve impulse GO:0019226 42 0.013
response to monosaccharide GO:0034284 159 0.013
developmental growth GO:0048589 100 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
multicellular organism reproduction GO:0032504 233 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
regulation of membrane potential GO:0042391 110 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
single organism behavior GO:0044708 130 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
heart morphogenesis GO:0003007 3 0.013
negative regulation of signaling GO:0023057 157 0.013
homeostatic process GO:0042592 331 0.012
mitotic spindle organization GO:0007052 2 0.012
single organism organelle organization GO:1902589 180 0.012
multicellular organism growth GO:0035264 1 0.012
nitrogen compound transport GO:0071705 229 0.012
cardiac conduction GO:0061337 2 0.012
negative regulation of organ growth GO:0046621 3 0.012
regulation of protein kinase activity GO:0045859 105 0.012
positive regulation of transferase activity GO:0051347 81 0.012
nucleotide catabolic process GO:0009166 139 0.012
dendrite morphogenesis GO:0048813 43 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regulation of hydrolase activity GO:0051336 143 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
aging GO:0007568 241 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular component morphogenesis GO:0032989 155 0.012
anterior posterior pattern specification GO:0009952 1 0.012
cell morphogenesis GO:0000902 142 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
defense response GO:0006952 194 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
aromatic compound catabolic process GO:0019439 168 0.011
epithelium development GO:0060429 96 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
positive regulation of catabolic process GO:0009896 78 0.011
intracellular transport GO:0046907 185 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
response to glucose GO:0009749 136 0.011
amide biosynthetic process GO:0043604 10 0.011
regulation of kinase activity GO:0043549 117 0.011
response to nutrient GO:0007584 248 0.011
fatty acid metabolic process GO:0006631 99 0.011
neuron projection morphogenesis GO:0048812 122 0.011
axis specification GO:0009798 4 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
insulin receptor signaling pathway GO:0008286 24 0.011
regulation of transmembrane transport GO:0034762 122 0.011
regulation of hormone levels GO:0010817 187 0.011
purine containing compound catabolic process GO:0072523 138 0.011
lipid biosynthetic process GO:0008610 128 0.011
dendrite development GO:0016358 72 0.011
regulation of cell growth GO:0001558 85 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
regulation of peptide secretion GO:0002791 82 0.011
gamete generation GO:0007276 124 0.011
reproduction GO:0000003 245 0.011
regulation of transferase activity GO:0051338 123 0.011
intracellular protein transport GO:0006886 79 0.010
negative regulation of transport GO:0051051 136 0.010
lipid storage GO:0019915 1 0.010
Fly
gland development GO:0048732 155 0.010
cellular ion homeostasis GO:0006873 184 0.010
regulation of chromosome segregation GO:0051983 1 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
organophosphate catabolic process GO:0046434 148 0.010
muscle structure development GO:0061061 87 0.010
regulation of mapk cascade GO:0043408 116 0.010
negative regulation of molecular function GO:0044092 133 0.010
cell part morphogenesis GO:0032990 123 0.010

Wdtc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
sensory system disease DOID:0050155 0 0.016
neuromuscular disease DOID:440 0 0.014
neuropathy DOID:870 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
musculoskeletal system disease DOID:17 0 0.012
central nervous system disease DOID:331 0 0.011
charcot marie tooth disease type 2 DOID:0050539 0 0.010