Rattus norvegicus

78 known processes

Hmgb2

high mobility group box 2

(Aliases: MGC125103,MGC108899,Hmg2)

Hmgb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to heat GO:0009408 60 0.404
mrna metabolic process GO:0016071 20 0.305
negative regulation of cellular biosynthetic process GO:0031327 161 0.246
Human
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.173
Human
regulation of programmed cell death GO:0043067 341 0.168
Mouse
regulation of cellular component organization GO:0051128 368 0.157
central nervous system development GO:0007417 311 0.142
regulation of organelle organization GO:0033043 80 0.135
regulation of protein metabolic process GO:0051246 289 0.130
chromatin assembly or disassembly GO:0006333 1 0.128
negative regulation of cellular metabolic process GO:0031324 281 0.120
Human
negative regulation of rna splicing GO:0033119 3 0.119
organ regeneration GO:0031100 101 0.117
negative regulation of biosynthetic process GO:0009890 168 0.112
Human
regeneration GO:0031099 163 0.111
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.108
response to peptide GO:1901652 292 0.102
nucleic acid templated transcription GO:0097659 379 0.102
rna metabolic process GO:0016070 406 0.100
positive regulation of gene expression GO:0010628 244 0.099
aging GO:0007568 241 0.097
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.096
cell cycle GO:0007049 101 0.090
single organism reproductive process GO:0044702 297 0.089
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.088
Human
cellular response to endogenous stimulus GO:0071495 377 0.088
negative regulation of rna metabolic process GO:0051253 123 0.083
Human
brain development GO:0007420 247 0.077
negative regulation of gene expression GO:0010629 199 0.074
Human
regulation of apoptotic process GO:0042981 335 0.074
Mouse
response to wounding GO:0009611 254 0.074
head development GO:0060322 247 0.074
organelle organization GO:0006996 266 0.073
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.071
Human Mouse
cytoskeleton organization GO:0007010 111 0.068
negative regulation of macromolecule metabolic process GO:0010605 260 0.067
Human
mrna processing GO:0006397 14 0.065
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.063
single organism organelle organization GO:1902589 180 0.062
Mouse
dna packaging GO:0006323 4 0.061
dna metabolic process GO:0006259 96 0.061
regulation of multicellular organismal development GO:2000026 376 0.060
Human
rna biosynthetic process GO:0032774 380 0.057
positive regulation of biosynthetic process GO:0009891 319 0.057
response to temperature stimulus GO:0009266 94 0.057
regulation of dna metabolic process GO:0051052 60 0.056
hemidesmosome assembly GO:0031581 1 0.054
cell type specific apoptotic process GO:0097285 134 0.053
regulation of cell differentiation GO:0045595 320 0.053
Human
striated muscle tissue development GO:0014706 58 0.053
negative regulation of protein metabolic process GO:0051248 114 0.053
cell cycle checkpoint GO:0000075 2 0.052
cellular response to organonitrogen compound GO:0071417 197 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.051
cellular component assembly GO:0022607 360 0.048
response to peptide hormone GO:0043434 278 0.045
regulation of mrna splicing via spliceosome GO:0048024 3 0.045
macromolecular complex assembly GO:0065003 273 0.043
multi organism reproductive process GO:0044703 262 0.042
Mouse
spermatogenesis GO:0007283 99 0.041
Mouse
reproduction GO:0000003 245 0.041
Mouse
positive regulation of lipid catabolic process GO:0050996 4 0.041
cellular response to nitrogen compound GO:1901699 210 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
negative regulation of metabolic process GO:0009892 331 0.041
Human
protein complex assembly GO:0006461 263 0.040
growth GO:0040007 165 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
programmed cell death GO:0012501 392 0.037
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.037
positive regulation of developmental process GO:0051094 283 0.036
Human
striated muscle cell development GO:0055002 26 0.035
reproductive process GO:0022414 372 0.035
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
Human
mesenchymal cell proliferation GO:0010463 4 0.034
transcription dna templated GO:0006351 377 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
positive regulation of neurogenesis GO:0050769 165 0.033
regulation of rna metabolic process GO:0051252 391 0.033
neuron differentiation GO:0030182 368 0.033
positive regulation of cell proliferation GO:0008284 249 0.032
Human
chromosome segregation GO:0007059 2 0.032
protein homooligomerization GO:0051260 91 0.032
axis specification GO:0009798 4 0.031
response to estradiol GO:0032355 164 0.031
regulation of response to stress GO:0080134 126 0.031
circadian rhythm GO:0007623 88 0.030
response to cytokine GO:0034097 215 0.030
gamete generation GO:0007276 124 0.030
Mouse
dna replication GO:0006260 37 0.030
regulation of neurogenesis GO:0050767 247 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
regulation of cell proliferation GO:0042127 359 0.028
Human
regulation of transcription dna templated GO:0006355 374 0.028
muscle structure development GO:0061061 87 0.028
regulation of cell development GO:0060284 263 0.028
negative regulation of cell cycle phase transition GO:1901988 4 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
Human
chromatin remodeling GO:0006338 3 0.027
regulation of cell cycle GO:0051726 73 0.027
apoptotic process GO:0006915 381 0.027
Mouse
anatomical structure morphogenesis GO:0009653 298 0.026
response to extracellular stimulus GO:0009991 380 0.026
female sex differentiation GO:0046660 59 0.025
negative regulation of transcription dna templated GO:0045892 116 0.024
Human
response to acid chemical GO:0001101 222 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
rna localization GO:0006403 4 0.023
protein complex biogenesis GO:0070271 263 0.023
positive regulation of nervous system development GO:0051962 178 0.023
cellular component biogenesis GO:0044085 368 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
Human
lens development in camera type eye GO:0002088 13 0.021
protein complex subunit organization GO:0071822 302 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
regulation of growth GO:0040008 105 0.021
regulation of catalytic activity GO:0050790 304 0.021
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
Human Mouse
anterior posterior pattern specification GO:0009952 1 0.020
positive regulation of cell development GO:0010720 176 0.020
negative regulation of cell death GO:0060548 229 0.020
Mouse
macromolecule localization GO:0033036 252 0.020
muscle organ development GO:0007517 50 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
response to interleukin 1 GO:0070555 55 0.020
reproductive structure development GO:0048608 128 0.020
Mouse
sensory organ development GO:0007423 74 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
Human
response to nutrient levels GO:0031667 370 0.019
chromatin organization GO:0006325 34 0.019
multicellular organism reproduction GO:0032504 233 0.019
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.019
response to hydrogen peroxide GO:0042542 89 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
negative regulation of molecular function GO:0044092 133 0.019
cellular component morphogenesis GO:0032989 155 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.019
Human
positive regulation of protein metabolic process GO:0051247 178 0.018
response to cadmium ion GO:0046686 35 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.018
neuron development GO:0048666 286 0.018
sex differentiation GO:0007548 113 0.018
Mouse
response to insulin GO:0032868 133 0.018
regulation of cytoskeleton organization GO:0051493 49 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
Human Mouse
regulation of cell projection organization GO:0031344 175 0.017
reproductive system development GO:0061458 128 0.017
Mouse
gonad development GO:0008406 104 0.017
Mouse
innate immune response GO:0045087 35 0.017
regulation of striated muscle tissue development GO:0016202 25 0.016
regulation of muscle tissue development GO:1901861 25 0.016
protein localization to chromosome centromeric region GO:0071459 1 0.016
endoplasmic reticulum to cytosol transport GO:1903513 4 0.016
response to inorganic substance GO:0010035 377 0.016
chromatin modification GO:0016568 33 0.016
embryonic pattern specification GO:0009880 1 0.015
wound healing GO:0042060 122 0.015
nucleic acid transport GO:0050657 3 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
Human
response to metal ion GO:0010038 253 0.015
sexual reproduction GO:0019953 148 0.015
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of nervous system development GO:0051960 264 0.014
gliogenesis GO:0042063 93 0.014
regulation of molecular function GO:0065009 398 0.014
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
developmental process involved in reproduction GO:0003006 159 0.014
Mouse
camera type eye development GO:0043010 48 0.014
male gamete generation GO:0048232 99 0.014
Mouse
cellular macromolecule localization GO:0070727 122 0.014
protein localization GO:0008104 191 0.014
muscle cell development GO:0055001 26 0.014
regulation of mrna processing GO:0050684 5 0.014
mitotic cell cycle GO:0000278 49 0.013
cell cycle g1 s phase transition GO:0044843 13 0.013
rna processing GO:0006396 22 0.013
rhythmic process GO:0048511 156 0.013
tissue development GO:0009888 252 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
chemotaxis GO:0006935 66 0.013
Human
response to estrogen GO:0043627 232 0.013
regulation of neuron differentiation GO:0045664 208 0.013
pyrimidine nucleobase metabolic process GO:0006206 8 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
regulation of response to wounding GO:1903034 69 0.013
positive regulation of organelle organization GO:0010638 48 0.013
rna splicing GO:0008380 11 0.013
response to reactive oxygen species GO:0000302 120 0.013
calcium ion transport GO:0006816 131 0.013
muscle tissue development GO:0060537 58 0.012
positive regulation of dna metabolic process GO:0051054 39 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
positive regulation of lipid metabolic process GO:0045834 33 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
positive regulation of fibroblast proliferation GO:0048146 15 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of inflammatory response GO:0050727 48 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
response to oxidative stress GO:0006979 186 0.012
cell projection organization GO:0030030 302 0.011
myeloid cell apoptotic process GO:0033028 6 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
regulation of defense response GO:0031347 68 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
Mouse
cardiac muscle tissue growth GO:0055017 20 0.011
embryonic axis specification GO:0000578 1 0.011
dna conformation change GO:0071103 10 0.011
mitotic dna damage checkpoint GO:0044773 1 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
response to oxygen levels GO:0070482 265 0.011
cardiac cell development GO:0055006 16 0.011
mrna stabilization GO:0048255 2 0.011
nucleosome organization GO:0034728 1 0.010
protein oligomerization GO:0051259 191 0.010
positive regulation of programmed cell death GO:0043068 157 0.010

Hmgb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org