Rattus norvegicus

0 known processes

Atxn2

ataxin 2

(Aliases: Sca2)

Atxn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.132
organic acid metabolic process GO:0006082 292 0.113
carboxylic acid metabolic process GO:0019752 289 0.096
synaptic growth at neuromuscular junction GO:0051124 1 0.089
regulation of signal transduction GO:0009966 318 0.077
cell projection organization GO:0030030 302 0.076
cellular response to endogenous stimulus GO:0071495 377 0.075
neuron development GO:0048666 286 0.070
protein phosphorylation GO:0006468 345 0.068
neuron differentiation GO:0030182 368 0.066
regulation of rna metabolic process GO:0051252 391 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.064
positive regulation of phosphate metabolic process GO:0045937 262 0.063
cell projection morphogenesis GO:0048858 123 0.061
regulation of cellular ketone metabolic process GO:0010565 27 0.060
regulation of multicellular organismal development GO:2000026 376 0.059
regulation of cell differentiation GO:0045595 320 0.058
regulation of cellular component organization GO:0051128 368 0.057
neuron projection development GO:0031175 273 0.056
anatomical structure morphogenesis GO:0009653 298 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.055
intracellular signal transduction GO:0035556 314 0.054
positive regulation of developmental process GO:0051094 283 0.054
positive regulation of phosphorylation GO:0042327 177 0.053
transcription dna templated GO:0006351 377 0.053
regulation of intracellular signal transduction GO:1902531 218 0.051
regulation of programmed cell death GO:0043067 341 0.050
rna biosynthetic process GO:0032774 380 0.048
regulation of apoptotic process GO:0042981 335 0.047
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
regulation of cell development GO:0060284 263 0.046
regulation of rna biosynthetic process GO:2001141 381 0.045
cellular catabolic process GO:0044248 295 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.044
programmed cell death GO:0012501 392 0.043
catabolic process GO:0009056 351 0.043
positive regulation of molecular function GO:0044093 230 0.043
regulation of phosphorylation GO:0042325 248 0.042
neurological system process GO:0050877 219 0.042
amine metabolic process GO:0009308 38 0.040
regulation of transcription dna templated GO:0006355 374 0.040
cellular amine metabolic process GO:0044106 38 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
negative regulation of cell communication GO:0010648 158 0.039
ribonucleotide metabolic process GO:0009259 231 0.038
regulation of hydrolase activity GO:0051336 143 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
positive regulation of cell differentiation GO:0045597 217 0.036
regulation of protein metabolic process GO:0051246 289 0.036
regulation of protein modification process GO:0031399 194 0.036
cellular component morphogenesis GO:0032989 155 0.036
cellular component movement GO:0006928 248 0.035
regulation of system process GO:0044057 208 0.035
positive regulation of cell death GO:0010942 184 0.035
cellular component biogenesis GO:0044085 368 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
organic substance catabolic process GO:1901575 316 0.034
cell part morphogenesis GO:0032990 123 0.034
regulation of neuron projection development GO:0010975 161 0.034
cellular component assembly GO:0022607 360 0.034
single organism carbohydrate metabolic process GO:0044723 118 0.034
regulation of neuron differentiation GO:0045664 208 0.033
cellular response to lipid GO:0071396 201 0.033
regulation of molecular function GO:0065009 398 0.033
regulation of synaptic transmission GO:0050804 141 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
carbohydrate metabolic process GO:0005975 130 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
regulation of nervous system development GO:0051960 264 0.032
negative regulation of signal transduction GO:0009968 83 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
rna metabolic process GO:0016070 406 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
single organism catabolic process GO:0044712 283 0.031
behavior GO:0007610 205 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
oxidation reduction process GO:0055114 304 0.031
protein complex biogenesis GO:0070271 263 0.030
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
response to extracellular stimulus GO:0009991 380 0.030
positive regulation of cell development GO:0010720 176 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
negative regulation of signaling GO:0023057 157 0.029
apoptotic process GO:0006915 381 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
cellular response to stress GO:0033554 269 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of cellular component movement GO:0051270 150 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
purine containing compound metabolic process GO:0072521 253 0.027
regulation of cell projection organization GO:0031344 175 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
regulation of proteasomal protein catabolic process GO:0061136 4 0.027
cellular ketone metabolic process GO:0042180 51 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
protein complex assembly GO:0006461 263 0.026
macromolecular complex assembly GO:0065003 273 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
multi organism reproductive process GO:0044703 262 0.026
positive regulation of gene expression GO:0010628 244 0.025
regulation of neurogenesis GO:0050767 247 0.025
nucleic acid templated transcription GO:0097659 379 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
single organism biosynthetic process GO:0044711 342 0.025
regulation of catalytic activity GO:0050790 304 0.025
non canonical wnt signaling pathway GO:0035567 3 0.025
synaptic transmission GO:0007268 235 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
response to growth factor GO:0070848 189 0.025
cellular lipid metabolic process GO:0044255 208 0.025
positive regulation of cell communication GO:0010647 271 0.025
single organism reproductive process GO:0044702 297 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
positive regulation of programmed cell death GO:0043068 157 0.024
regulation of catabolic process GO:0009894 113 0.024
response to inorganic substance GO:0010035 377 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
locomotion GO:0040011 237 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
response to hypoxia GO:0001666 231 0.024
negative regulation of cell death GO:0060548 229 0.024
cognition GO:0050890 92 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.024
positive regulation of signaling GO:0023056 270 0.024
regulation of membrane potential GO:0042391 110 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.023
regulation of cell growth GO:0001558 85 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
organophosphate metabolic process GO:0019637 370 0.022
nucleotide metabolic process GO:0009117 279 0.022
response to metal ion GO:0010038 253 0.022
peptidyl amino acid modification GO:0018193 126 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
response to nutrient levels GO:0031667 370 0.022
heterocycle catabolic process GO:0046700 167 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
lipid metabolic process GO:0006629 283 0.022
positive regulation of hydrolase activity GO:0051345 86 0.022
regulation of anatomical structure size GO:0090066 135 0.022
regulation of cell morphogenesis GO:0022604 77 0.022
brain development GO:0007420 247 0.021
negative regulation of metabolic process GO:0009892 331 0.021
cell migration GO:0016477 197 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
ion homeostasis GO:0050801 212 0.021
cell morphogenesis GO:0000902 142 0.021
negative regulation of transport GO:0051051 136 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to oxygen levels GO:0070482 265 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
reproduction GO:0000003 245 0.021
cell growth GO:0016049 104 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
regulation of hormone levels GO:0010817 187 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
negative regulation of gene expression GO:0010629 199 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
mapk cascade GO:0000165 140 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
single organism behavior GO:0044708 130 0.020
regulation of homeostatic process GO:0032844 101 0.020
reproductive process GO:0022414 372 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
dendrite morphogenesis GO:0048813 43 0.020
tissue development GO:0009888 252 0.019
response to acid chemical GO:0001101 222 0.019
olfactory learning GO:0008355 1 0.019
single organism intracellular transport GO:1902582 166 0.019
cell cell signaling GO:0007267 335 0.019
ras protein signal transduction GO:0007265 29 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
cell motility GO:0048870 202 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
signal transduction by phosphorylation GO:0023014 144 0.018
learning or memory GO:0007611 90 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
chromosome segregation GO:0007059 2 0.018
transmembrane transport GO:0055085 412 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
regulation of blood circulation GO:1903522 110 0.018
aromatic compound catabolic process GO:0019439 168 0.018
regulation of growth GO:0040008 105 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
intracellular transport GO:0046907 185 0.018
central nervous system development GO:0007417 311 0.018
axonogenesis GO:0007409 71 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
rhythmic process GO:0048511 156 0.017
positive regulation of protein modification process GO:0031401 142 0.017
localization of cell GO:0051674 202 0.017
growth GO:0040007 165 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of cell proliferation GO:0042127 359 0.017
cellular homeostasis GO:0019725 252 0.017
positive regulation of nervous system development GO:0051962 178 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of catabolic process GO:0009896 78 0.017
negative regulation of developmental process GO:0051093 125 0.017
cation transport GO:0006812 382 0.017
protein complex subunit organization GO:0071822 302 0.017
regulation of secretion GO:0051046 224 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
dendrite development GO:0016358 72 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
regulation of cell size GO:0008361 37 0.016
gastrulation GO:0007369 2 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.016
forebrain development GO:0030900 98 0.016
developmental growth GO:0048589 100 0.016
cardiovascular system development GO:0072358 134 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
calcium ion homeostasis GO:0055074 162 0.016
regeneration GO:0031099 163 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of stem cell differentiation GO:2000736 2 0.015
axon development GO:0061564 96 0.015
actin filament based process GO:0030029 86 0.015
head development GO:0060322 247 0.015
regulation of ion transport GO:0043269 245 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
protein oligomerization GO:0051259 191 0.015
regulation of kinase activity GO:0043549 117 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
chemosensory behavior GO:0007635 2 0.015
embryonic pattern specification GO:0009880 1 0.015
cellular chemical homeostasis GO:0055082 247 0.015
ion transmembrane transport GO:0034220 365 0.015
regulation of cellular localization GO:0060341 263 0.015
regulation of chromosome segregation GO:0051983 1 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of cell cycle GO:0051726 73 0.015
nucleoside metabolic process GO:0009116 179 0.015
muscle system process GO:0003012 115 0.015
proteolysis GO:0006508 175 0.015
response to glucocorticoid GO:0051384 223 0.015
mesoderm development GO:0007498 2 0.015
negative regulation of neurogenesis GO:0050768 78 0.014
biological adhesion GO:0022610 110 0.014
response to insulin GO:0032868 133 0.014
cellular ion homeostasis GO:0006873 184 0.014
axis specification GO:0009798 4 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to wounding GO:0009611 254 0.014
cytoplasmic transport GO:0016482 115 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
nucleoside catabolic process GO:0009164 126 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
response to corticosteroid GO:0031960 235 0.014
homeostatic process GO:0042592 331 0.014
response to toxic substance GO:0009636 133 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
reproductive structure development GO:0048608 128 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
spindle organization GO:0007051 2 0.014
heart morphogenesis GO:0003007 3 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of molecular function GO:0044092 133 0.014
chemical homeostasis GO:0048878 292 0.014
metal ion transport GO:0030001 289 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
action potential GO:0001508 54 0.014
intracellular protein transport GO:0006886 79 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
regulation of mapk cascade GO:0043408 116 0.013
regulation of axon extension GO:0030516 24 0.013
response to ethanol GO:0045471 162 0.013
eye morphogenesis GO:0048592 4 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
organelle organization GO:0006996 266 0.013
response to peptide GO:1901652 292 0.013
neuron projection morphogenesis GO:0048812 122 0.013
cellular protein localization GO:0034613 122 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of growth GO:0045927 55 0.013
multicellular organism growth GO:0035264 1 0.013
circulatory system development GO:0072359 134 0.013
purine containing compound catabolic process GO:0072523 138 0.013
multicellular organism reproduction GO:0032504 233 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to lipopolysaccharide GO:0032496 191 0.013
negative regulation of cell differentiation GO:0045596 99 0.012
sex differentiation GO:0007548 113 0.012
monosaccharide metabolic process GO:0005996 61 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
dephosphorylation GO:0016311 98 0.012
male gamete generation GO:0048232 99 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
gamete generation GO:0007276 124 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
response to cytokine GO:0034097 215 0.012
cellular macromolecule localization GO:0070727 122 0.012
response to nutrient GO:0007584 248 0.012
sexual reproduction GO:0019953 148 0.012
regulation of dendrite morphogenesis GO:0048814 33 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
maintenance of location GO:0051235 17 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
second messenger mediated signaling GO:0019932 51 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of cell migration GO:0030334 128 0.012
circulatory system process GO:0003013 183 0.012
ribonucleotide catabolic process GO:0009261 136 0.011
macromolecule localization GO:0033036 252 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
regulation of cell motility GO:2000145 131 0.011
circadian rhythm GO:0007623 88 0.011
regulation of cellular component size GO:0032535 51 0.011
developmental growth involved in morphogenesis GO:0060560 33 0.011
rho protein signal transduction GO:0007266 11 0.011
metal ion homeostasis GO:0055065 186 0.011
cytoskeleton organization GO:0007010 111 0.011
cellular response to alcohol GO:0097306 87 0.011
hormone metabolic process GO:0042445 69 0.011
regulation of metal ion transport GO:0010959 118 0.011
regulation of developmental growth GO:0048638 45 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
positive regulation of ion transport GO:0043270 94 0.011
cell cycle GO:0007049 101 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
sequestering of metal ion GO:0051238 9 0.011
response to alkaloid GO:0043279 132 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
response to hexose GO:0009746 144 0.011
regulation of muscle system process GO:0090257 79 0.011
olfactory behavior GO:0042048 2 0.011
lipid biosynthetic process GO:0008610 128 0.011
neuronal action potential GO:0019228 35 0.011
fatty acid metabolic process GO:0006631 99 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
cellular response to acid chemical GO:0071229 75 0.011
positive regulation of signal transduction GO:0009967 175 0.011
regulation of gtpase activity GO:0043087 57 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of hormone secretion GO:0046883 106 0.011
gonad development GO:0008406 104 0.011
bmp signaling pathway GO:0030509 4 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
synapse assembly GO:0007416 29 0.010
appendage morphogenesis GO:0035107 4 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
small molecule biosynthetic process GO:0044283 124 0.010
regulation of protein kinase activity GO:0045859 105 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
carbohydrate catabolic process GO:0016052 40 0.010
protein autophosphorylation GO:0046777 66 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
regulation of extent of cell growth GO:0061387 25 0.010
negative regulation of nervous system development GO:0051961 79 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
protein localization GO:0008104 191 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
establishment of protein localization to organelle GO:0072594 44 0.010
peptidyl serine phosphorylation GO:0018105 33 0.010
response to other organism GO:0051707 220 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
somatic stem cell maintenance GO:0035019 2 0.010
negative regulation of neuron differentiation GO:0045665 62 0.010

Atxn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.017
central nervous system disease DOID:331 0 0.012
sensory system disease DOID:0050155 0 0.011