Rattus norvegicus

40 known processes

Gnrh1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

(Aliases: Rgnrhg1,Gnrh,Lhrh,Gnrha)

Gnrh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism catabolic process GO:0044712 283 0.173
ion transmembrane transport GO:0034220 365 0.140
metal ion transport GO:0030001 289 0.134
carboxylic acid metabolic process GO:0019752 289 0.107
organic substance catabolic process GO:1901575 316 0.092
cardiac muscle contraction GO:0060048 27 0.083
vesicle mediated transport GO:0016192 181 0.066
cation transport GO:0006812 382 0.065
regulation of vesicle mediated transport GO:0060627 81 0.064
transmembrane transport GO:0055085 412 0.064
regulation of neurogenesis GO:0050767 247 0.059
cardiac muscle cell contraction GO:0086003 10 0.059
tissue development GO:0009888 252 0.058
brain development GO:0007420 247 0.055
steroid biosynthetic process GO:0006694 48 0.053
steroid metabolic process GO:0008202 73 0.052
regulation of cellular ketone metabolic process GO:0010565 27 0.050
cellular ion homeostasis GO:0006873 184 0.050
regulation of cellular component organization GO:0051128 368 0.049
hormone metabolic process GO:0042445 69 0.049
regulation of phosphate metabolic process GO:0019220 349 0.049
protein complex assembly GO:0006461 263 0.047
response to organophosphorus GO:0046683 102 0.046
regulation of striated muscle contraction GO:0006942 21 0.045
lipid biosynthetic process GO:0008610 128 0.045
positive regulation of biosynthetic process GO:0009891 319 0.042
single organism biosynthetic process GO:0044711 342 0.041
negative regulation of gene expression GO:0010629 199 0.041
homeostatic process GO:0042592 331 0.040
lipid metabolic process GO:0006629 283 0.039
striated muscle contraction GO:0006941 44 0.039
intracellular transport GO:0046907 185 0.038
actin mediated cell contraction GO:0070252 12 0.038
response to acid chemical GO:0001101 222 0.036
catabolic process GO:0009056 351 0.036
cation transmembrane transport GO:0098655 263 0.035
organic acid metabolic process GO:0006082 292 0.035
regulation of phosphorylation GO:0042325 248 0.035
divalent inorganic cation homeostasis GO:0072507 165 0.034
anatomical structure morphogenesis GO:0009653 298 0.034
regulation of cell development GO:0060284 263 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
macromolecular complex assembly GO:0065003 273 0.034
carbohydrate metabolic process GO:0005975 130 0.033
calcium ion transport GO:0006816 131 0.033
thyroid gland development GO:0030878 1 0.033
response to carbohydrate GO:0009743 183 0.032
response to hexose GO:0009746 144 0.032
reproductive process GO:0022414 372 0.032
oxoacid metabolic process GO:0043436 290 0.031
regulation of system process GO:0044057 208 0.031
negative regulation of response to stimulus GO:0048585 155 0.030
nitrogen compound transport GO:0071705 229 0.030
monocarboxylic acid metabolic process GO:0032787 152 0.030
purine ribonucleotide biosynthetic process GO:0009152 81 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
cellular ketone metabolic process GO:0042180 51 0.030
divalent metal ion transport GO:0070838 132 0.030
single organism intracellular transport GO:1902582 166 0.030
organic cyclic compound catabolic process GO:1901361 175 0.029
blood circulation GO:0008015 183 0.029
regulation of molecular function GO:0065009 398 0.029
aromatic compound catabolic process GO:0019439 168 0.029
response to increased oxygen levels GO:0036296 45 0.028
response to inorganic substance GO:0010035 377 0.028
ribonucleotide metabolic process GO:0009259 231 0.027
cellular chemical homeostasis GO:0055082 247 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
regulation of blood circulation GO:1903522 110 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.026
regulation of cellular localization GO:0060341 263 0.026
response to purine containing compound GO:0014074 126 0.026
telencephalon development GO:0021537 62 0.026
potassium ion transport GO:0006813 97 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.025
inorganic cation transmembrane transport GO:0098662 202 0.025
cardiac ventricle development GO:0003231 1 0.025
ribonucleotide biosynthetic process GO:0009260 85 0.025
central nervous system development GO:0007417 311 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
chemical homeostasis GO:0048878 292 0.025
response to cytokine GO:0034097 215 0.025
cell cell signaling GO:0007267 335 0.024
purine containing compound metabolic process GO:0072521 253 0.024
ribose phosphate metabolic process GO:0019693 235 0.023
insulin secretion GO:0030073 69 0.023
oxidation reduction process GO:0055114 304 0.023
heart process GO:0003015 57 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
response to radiation GO:0009314 137 0.023
organophosphate metabolic process GO:0019637 370 0.023
response to hyperoxia GO:0055093 45 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
response to nutrient levels GO:0031667 370 0.022
glucose homeostasis GO:0042593 75 0.022
negative regulation of metabolic process GO:0009892 331 0.022
heart morphogenesis GO:0003007 3 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
cellular homeostasis GO:0019725 252 0.021
regulation of heart contraction GO:0008016 48 0.021
programmed cell death GO:0012501 392 0.021
regulation of ion transport GO:0043269 245 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
cellular catabolic process GO:0044248 295 0.021
response to monosaccharide GO:0034284 159 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
regulation of signal transduction GO:0009966 318 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
neurological system process GO:0050877 219 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
heart contraction GO:0060047 57 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
heterocycle catabolic process GO:0046700 167 0.020
divalent inorganic cation transport GO:0072511 134 0.020
purine nucleotide biosynthetic process GO:0006164 83 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
organelle organization GO:0006996 266 0.020
response to ethanol GO:0045471 162 0.020
rna biosynthetic process GO:0032774 380 0.020
leukocyte cell cell adhesion GO:0007159 4 0.020
cellular component movement GO:0006928 248 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
response to peptide GO:1901652 292 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
reactive nitrogen species metabolic process GO:2001057 1 0.019
muscle tissue morphogenesis GO:0060415 1 0.019
positive regulation of molecular function GO:0044093 230 0.019
protein complex biogenesis GO:0070271 263 0.019
mechanoreceptor differentiation GO:0042490 2 0.019
cell projection organization GO:0030030 302 0.019
positive regulation of cell differentiation GO:0045597 217 0.018
adult locomotory behavior GO:0008344 4 0.018
neuron differentiation GO:0030182 368 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cellular lipid metabolic process GO:0044255 208 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
multicellular organismal signaling GO:0035637 44 0.017
muscle system process GO:0003012 115 0.017
positive regulation of cell communication GO:0010647 271 0.017
response to oxygen levels GO:0070482 265 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
regulation of cardiac muscle contraction GO:0055117 17 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
positive regulation of long term synaptic potentiation GO:1900273 4 0.017
regulation of hormone levels GO:0010817 187 0.017
cellular response to stress GO:0033554 269 0.017
response to glucose GO:0009749 136 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
regulation of transmembrane transport GO:0034762 122 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
response to metal ion GO:0010038 253 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
proteolysis GO:0006508 175 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
organophosphate catabolic process GO:0046434 148 0.015
amine metabolic process GO:0009308 38 0.015
positive regulation of lyase activity GO:0051349 15 0.015
peptide secretion GO:0002790 86 0.015
regulation of muscle system process GO:0090257 79 0.015
circulatory system process GO:0003013 183 0.015
regulation of nervous system development GO:0051960 264 0.015
epithelium development GO:0060429 96 0.015
carbohydrate homeostasis GO:0033500 75 0.015
anterior posterior pattern specification GO:0009952 1 0.015
neuron projection development GO:0031175 273 0.015
actin filament based process GO:0030029 86 0.015
nucleic acid templated transcription GO:0097659 379 0.015
maintenance of location GO:0051235 17 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of neuron projection development GO:0010975 161 0.015
response to decreased oxygen levels GO:0036293 237 0.015
myosin filament organization GO:0031033 2 0.015
reproductive structure development GO:0048608 128 0.015
positive regulation of cell death GO:0010942 184 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cellular hormone metabolic process GO:0034754 49 0.015
regulation of peptide secretion GO:0002791 82 0.015
response to peptide hormone GO:0043434 278 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
sequestering of metal ion GO:0051238 9 0.014
head development GO:0060322 247 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
positive regulation of developmental process GO:0051094 283 0.014
membrane repolarization GO:0086009 1 0.014
response to bacterium GO:0009617 200 0.014
regulation of cardiac muscle cell contraction GO:0086004 11 0.014
positive regulation of nervous system development GO:0051962 178 0.014
transcription dna templated GO:0006351 377 0.014
nucleotide metabolic process GO:0009117 279 0.014
sleep GO:0030431 30 0.014
sensory perception of pain GO:0019233 73 0.014
fertilization GO:0009566 3 0.014
cgmp biosynthetic process GO:0006182 15 0.014
regulation of sodium ion transport GO:0002028 21 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of actin filament based movement GO:1903115 12 0.013
positive regulation of cation channel activity GO:2001259 11 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
regulation of lipid biosynthetic process GO:0046890 38 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
monosaccharide metabolic process GO:0005996 61 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
response to extracellular stimulus GO:0009991 380 0.013
regulation of calcium ion transport GO:0051924 77 0.013
regulation of catalytic activity GO:0050790 304 0.013
organic acid catabolic process GO:0016054 49 0.013
peptide transport GO:0015833 97 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
limbic system development GO:0021761 38 0.013
regulation of rna metabolic process GO:0051252 391 0.013
cellular response to carbohydrate stimulus GO:0071322 72 0.013
positive regulation of signal transduction GO:0009967 175 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
growth GO:0040007 165 0.012
response to camp GO:0051591 91 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
nucleoside catabolic process GO:0009164 126 0.012
lipid storage GO:0019915 1 0.012
defense response GO:0006952 194 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
carboxylic acid transport GO:0046942 115 0.012
purine nucleoside monophosphate catabolic process GO:0009128 55 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
negative adaptation of signaling pathway GO:0022401 10 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
gamete generation GO:0007276 124 0.012
cytoplasmic transport GO:0016482 115 0.012
actin filament based movement GO:0030048 16 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
regulation of blood pressure GO:0008217 83 0.012
l glutamate import GO:0051938 2 0.012
regulation of organelle organization GO:0033043 80 0.012
cardiac muscle tissue morphogenesis GO:0055008 1 0.012
reproductive system development GO:0061458 128 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of cell differentiation GO:0045595 320 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of cell proliferation GO:0042127 359 0.011
sex differentiation GO:0007548 113 0.011
muscle structure development GO:0061061 87 0.011
intracellular signal transduction GO:0035556 314 0.011
regulation of mapk cascade GO:0043408 116 0.011
calcium ion import GO:0070509 22 0.011
response to glucocorticoid GO:0051384 223 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
purine containing compound catabolic process GO:0072523 138 0.011
optic nerve development GO:0021554 3 0.011
response to calcium ion GO:0051592 59 0.011
tube formation GO:0035148 3 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
cation homeostasis GO:0055080 195 0.011
regulation of programmed cell death GO:0043067 341 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
regulation of metal ion transport GO:0010959 118 0.011
peptide hormone secretion GO:0030072 84 0.011
response to estradiol GO:0032355 164 0.010
detection of temperature stimulus GO:0016048 4 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
negative regulation of transport GO:0051051 136 0.010
cellular amine metabolic process GO:0044106 38 0.010
sodium ion transport GO:0006814 82 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
positive regulation of gene expression GO:0010628 244 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cardiac chamber development GO:0003205 1 0.010
response to external biotic stimulus GO:0043207 221 0.010
cardiovascular system development GO:0072358 134 0.010
cardiac muscle cell development GO:0055013 16 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.010
single organism reproductive process GO:0044702 297 0.010
negative regulation of cell death GO:0060548 229 0.010
g protein coupled receptor internalization GO:0002031 3 0.010
cellular response to monosaccharide stimulus GO:0071326 67 0.010
negative regulation of cell communication GO:0010648 158 0.010
positive regulation of cell development GO:0010720 176 0.010

Gnrh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.114
cardiovascular system disease DOID:1287 0 0.114
heart disease DOID:114 0 0.041
disease of metabolism DOID:0014667 0 0.035
congenital heart disease DOID:1682 0 0.018
heart septal defect DOID:1681 0 0.018
endocrine system disease DOID:28 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
cardiomyopathy DOID:0050700 0 0.013
dilated cardiomyopathy DOID:12930 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
central nervous system disease DOID:331 0 0.012
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012