Rattus norvegicus

0 known processes

Cyth2

cytohesin 2

(Aliases: Pscd2,Arno,Sec7,Sec7B)

Cyth2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.321
regulation of rna biosynthetic process GO:2001141 381 0.282
rna biosynthetic process GO:0032774 380 0.268
regulation of nucleic acid templated transcription GO:1903506 380 0.267
transcription dna templated GO:0006351 377 0.208
nucleic acid templated transcription GO:0097659 379 0.182
macromolecular complex subunit organization GO:0043933 339 0.171
regulation of rna metabolic process GO:0051252 391 0.168
single organism organelle organization GO:1902589 180 0.163
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.160
rna metabolic process GO:0016070 406 0.148
transcription from rna polymerase ii promoter GO:0006366 252 0.146
positive regulation of biosynthetic process GO:0009891 319 0.145
regulation of cellular component organization GO:0051128 368 0.129
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.115
negative regulation of metabolic process GO:0009892 331 0.110
negative regulation of cellular metabolic process GO:0031324 281 0.107
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.096
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.095
Mouse
negative regulation of rna metabolic process GO:0051253 123 0.095
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.094
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.094
positive regulation of rna metabolic process GO:0051254 203 0.088
positive regulation of cellular biosynthetic process GO:0031328 295 0.083
negative regulation of gene expression GO:0010629 199 0.082
organelle organization GO:0006996 266 0.081
Fly
regulation of molecular function GO:0065009 398 0.079
Mouse Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.079
positive regulation of rna biosynthetic process GO:1902680 197 0.074
negative regulation of cellular biosynthetic process GO:0031327 161 0.073
protein complex subunit organization GO:0071822 302 0.073
positive regulation of nucleic acid templated transcription GO:1903508 197 0.071
cell type specific apoptotic process GO:0097285 134 0.070
cellular amino acid metabolic process GO:0006520 107 0.070
positive regulation of gene expression GO:0010628 244 0.068
regulation of hydrolase activity GO:0051336 143 0.067
Mouse
neuron death GO:0070997 127 0.063
regulation of catalytic activity GO:0050790 304 0.061
Mouse Fly
protein phosphorylation GO:0006468 345 0.061
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
Mouse
regulation of programmed cell death GO:0043067 341 0.060
regulation of apoptotic process GO:0042981 335 0.059
organic acid metabolic process GO:0006082 292 0.059
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.058
apoptotic process GO:0006915 381 0.057
central nervous system development GO:0007417 311 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.053
Mouse Fly
positive regulation of transcription dna templated GO:0045893 197 0.052
negative regulation of cell death GO:0060548 229 0.052
negative regulation of biosynthetic process GO:0009890 168 0.052
intracellular transport GO:0046907 185 0.051
reproductive process GO:0022414 372 0.051
oxoacid metabolic process GO:0043436 290 0.051
cellular response to oxygen containing compound GO:1901701 386 0.050
neuron differentiation GO:0030182 368 0.050
macromolecular complex assembly GO:0065003 273 0.050
carboxylic acid metabolic process GO:0019752 289 0.050
cellular component movement GO:0006928 248 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.049
regulation of cell differentiation GO:0045595 320 0.047
programmed cell death GO:0012501 392 0.047
cell projection organization GO:0030030 302 0.046
negative regulation of rna biosynthetic process GO:1902679 118 0.046
regulation of neuron death GO:1901214 115 0.046
cellular response to endogenous stimulus GO:0071495 377 0.046
regulation of protein modification process GO:0031399 194 0.045
Fly
regulation of protein phosphorylation GO:0001932 183 0.044
Fly
regulation of multicellular organismal development GO:2000026 376 0.043
cellular amine metabolic process GO:0044106 38 0.042
cellular ketone metabolic process GO:0042180 51 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.042
positive regulation of cell differentiation GO:0045597 217 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.041
regulation of phosphate metabolic process GO:0019220 349 0.041
Mouse Fly
head development GO:0060322 247 0.040
tissue development GO:0009888 252 0.039
cellular response to lipid GO:0071396 201 0.039
protein localization GO:0008104 191 0.038
cytoskeleton organization GO:0007010 111 0.038
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.038
Fly
regulation of cellular localization GO:0060341 263 0.038
negative regulation of apoptotic process GO:0043066 181 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
neuron development GO:0048666 286 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
Mouse Fly
cellular response to hormone stimulus GO:0032870 247 0.036
cellular catabolic process GO:0044248 295 0.036
Mouse
response to nutrient GO:0007584 248 0.035
cell cycle GO:0007049 101 0.035
macromolecule localization GO:0033036 252 0.035
multi organism reproductive process GO:0044703 262 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
Fly
cellular response to stress GO:0033554 269 0.035
multicellular organism reproduction GO:0032504 233 0.034
regulation of protein metabolic process GO:0051246 289 0.034
Fly
growth GO:0040007 165 0.034
Fly
brain development GO:0007420 247 0.034
response to acid chemical GO:0001101 222 0.034
positive regulation of protein metabolic process GO:0051247 178 0.033
Fly
response to corticosteroid GO:0031960 235 0.031
response to nutrient levels GO:0031667 370 0.031
neuron apoptotic process GO:0051402 88 0.030
cellular component assembly GO:0022607 360 0.030
cellular lipid metabolic process GO:0044255 208 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
Mouse Fly
regulation of signal transduction GO:0009966 318 0.030
Fly
single organism reproductive process GO:0044702 297 0.030
intracellular signal transduction GO:0035556 314 0.030
Fly
response to extracellular stimulus GO:0009991 380 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
regulation of nervous system development GO:0051960 264 0.029
amine metabolic process GO:0009308 38 0.029
cellular component biogenesis GO:0044085 368 0.029
protein complex biogenesis GO:0070271 263 0.029
response to glucocorticoid GO:0051384 223 0.029
regulation of cell development GO:0060284 263 0.028
developmental process involved in reproduction GO:0003006 159 0.028
single organism biosynthetic process GO:0044711 342 0.027
homeostatic process GO:0042592 331 0.027
response to estrogen GO:0043627 232 0.027
positive regulation of protein modification process GO:0031401 142 0.027
Fly
cellular response to organic cyclic compound GO:0071407 202 0.027
response to inorganic substance GO:0010035 377 0.027
locomotion GO:0040011 237 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of proteasomal protein catabolic process GO:0061136 4 0.026
neuron projection development GO:0031175 273 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
Fly
regulation of growth GO:0040008 105 0.025
Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
anterior posterior pattern specification GO:0009952 1 0.025
cation transport GO:0006812 382 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
Mouse Fly
positive regulation of response to stimulus GO:0048584 285 0.024
Fly
catabolic process GO:0009056 351 0.024
Mouse
response to peptide GO:1901652 292 0.024
cellular component morphogenesis GO:0032989 155 0.024
sexual reproduction GO:0019953 148 0.024
small molecule biosynthetic process GO:0044283 124 0.024
reproduction GO:0000003 245 0.023
aging GO:0007568 241 0.023
positive regulation of developmental process GO:0051094 283 0.023
Fly
axis specification GO:0009798 4 0.023
cell growth GO:0016049 104 0.023
double strand break repair GO:0006302 1 0.023
protein oligomerization GO:0051259 191 0.023
regulation of neuron apoptotic process GO:0043523 83 0.023
regulation of organelle organization GO:0033043 80 0.023
Fly
metal ion transport GO:0030001 289 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
embryonic pattern specification GO:0009880 1 0.022
single organism catabolic process GO:0044712 283 0.022
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.022
Mouse
lipid metabolic process GO:0006629 283 0.022
positive regulation of molecular function GO:0044093 230 0.022
Mouse Fly
response to reactive oxygen species GO:0000302 120 0.022
chemical homeostasis GO:0048878 292 0.021
regulation of neuron differentiation GO:0045664 208 0.021
cellular homeostasis GO:0019725 252 0.021
muscle structure development GO:0061061 87 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.021
Fly
cellular protein localization GO:0034613 122 0.021
positive regulation of cell development GO:0010720 176 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of cell death GO:0010942 184 0.021
lipid biosynthetic process GO:0008610 128 0.021
regulation of cell growth GO:0001558 85 0.020
regulation of cell projection organization GO:0031344 175 0.020
regulation of cell proliferation GO:0042127 359 0.020
regulation of transferase activity GO:0051338 123 0.020
Fly
response to peptide hormone GO:0043434 278 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
Mouse
purine containing compound metabolic process GO:0072521 253 0.020
Mouse
organic substance catabolic process GO:1901575 316 0.020
Mouse
positive regulation of phosphorylation GO:0042327 177 0.020
Fly
negative regulation of protein metabolic process GO:0051248 114 0.020
cell motility GO:0048870 202 0.020
response to wounding GO:0009611 254 0.019
oxidation reduction process GO:0055114 304 0.019
proteolysis GO:0006508 175 0.019
cellular chemical homeostasis GO:0055082 247 0.019
regulation of system process GO:0044057 208 0.019
response to ketone GO:1901654 182 0.019
response to growth factor GO:0070848 189 0.019
purine ribonucleoside catabolic process GO:0046130 124 0.019
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of neurogenesis GO:0050767 247 0.019
response to dexamethasone GO:0071548 49 0.019
negative regulation of signal transduction GO:0009968 83 0.019
organophosphate metabolic process GO:0019637 370 0.019
Mouse
regulation of phosphorylation GO:0042325 248 0.018
Fly
response to oxidative stress GO:0006979 186 0.018
vesicle mediated transport GO:0016192 181 0.018
Fly
positive regulation of cell projection organization GO:0031346 111 0.018
chromatin organization GO:0006325 34 0.018
single organism intracellular transport GO:1902582 166 0.018
nucleotide metabolic process GO:0009117 279 0.018
Mouse
protein autophosphorylation GO:0046777 66 0.018
striated muscle tissue development GO:0014706 58 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
gamete generation GO:0007276 124 0.018
protein heterooligomerization GO:0051291 89 0.018
positive regulation of programmed cell death GO:0043068 157 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of nervous system development GO:0051962 178 0.017
reproductive system development GO:0061458 128 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
heterocycle catabolic process GO:0046700 167 0.017
Mouse
spindle organization GO:0007051 2 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
ion transmembrane transport GO:0034220 365 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
Mouse
response to oxygen levels GO:0070482 265 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
transmembrane transport GO:0055085 412 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
Mouse
cell morphogenesis GO:0000902 142 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.015
cell adhesion GO:0007155 110 0.015
positive regulation of transport GO:0051050 245 0.015
gonad development GO:0008406 104 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.015
negative regulation of neuron death GO:1901215 69 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
neuron projection morphogenesis GO:0048812 122 0.015
endocytosis GO:0006897 84 0.015
Fly
regulation of protein localization GO:0032880 81 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
response to estradiol GO:0032355 164 0.015
protein complex assembly GO:0006461 263 0.015
response to cytokine GO:0034097 215 0.014
chromatin modification GO:0016568 33 0.014
ras protein signal transduction GO:0007265 29 0.014
secretion GO:0046903 307 0.014
mitotic spindle organization GO:0007052 2 0.014
multicellular organism growth GO:0035264 1 0.014
Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.014
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.014
Mouse
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.014
localization of cell GO:0051674 202 0.014
single organism cellular localization GO:1902580 102 0.014
cellular modified amino acid biosynthetic process GO:0042398 18 0.014
alternative mrna splicing via spliceosome GO:0000380 4 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
Mouse
negative regulation of rna splicing GO:0033119 3 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
Mouse
regulation of neuron projection development GO:0010975 161 0.014
cell part morphogenesis GO:0032990 123 0.014
response to radiation GO:0009314 137 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
eye morphogenesis GO:0048592 4 0.014
cytoplasmic transport GO:0016482 115 0.014
response to fatty acid GO:0070542 65 0.013
negative regulation of molecular function GO:0044092 133 0.013
axonogenesis GO:0007409 71 0.013
negative regulation of developmental process GO:0051093 125 0.013
dna metabolic process GO:0006259 96 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
alcohol metabolic process GO:0006066 77 0.013
response to vitamin GO:0033273 131 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of ion transport GO:0043269 245 0.013
insulin like growth factor receptor signaling pathway GO:0048009 3 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.013
Mouse
muscle system process GO:0003012 115 0.013
cell migration GO:0016477 197 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
Mouse
cellular macromolecule localization GO:0070727 122 0.013
response to metal ion GO:0010038 253 0.013
cell cycle process GO:0022402 57 0.013
development of primary sexual characteristics GO:0045137 107 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
Mouse
cellular response to nitrogen compound GO:1901699 210 0.012
cation homeostasis GO:0055080 195 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
Mouse
regulation of response to stress GO:0080134 126 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of proteolysis GO:0030162 66 0.012
asymmetric protein localization GO:0008105 2 0.012
response to decreased oxygen levels GO:0036293 237 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
Mouse
meiotic cell cycle process GO:1903046 3 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
biological adhesion GO:0022610 110 0.012
actin filament based process GO:0030029 86 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
response to hypoxia GO:0001666 231 0.012
regulation of secretion by cell GO:1903530 208 0.012
circulatory system development GO:0072359 134 0.012
histone modification GO:0016570 30 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
Mouse
protein maturation GO:0051604 68 0.012
heart morphogenesis GO:0003007 3 0.012
chemotaxis GO:0006935 66 0.012
regulation of synaptic transmission GO:0050804 141 0.012
response to hexose GO:0009746 144 0.012
regulation of protein kinase activity GO:0045859 105 0.011
Fly
muscle tissue development GO:0060537 58 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
Fly
chromosome segregation GO:0007059 2 0.011
protein dna complex disassembly GO:0032986 1 0.011
mrna processing GO:0006397 14 0.011
forebrain development GO:0030900 98 0.011
nucleoside metabolic process GO:0009116 179 0.011
Mouse
calcium ion homeostasis GO:0055074 162 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
dephosphorylation GO:0016311 98 0.011
response to hydrogen peroxide GO:0042542 89 0.011
regulation of ubiquitin protein transferase activity GO:0051438 1 0.011
cellular ion homeostasis GO:0006873 184 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
Mouse
negative regulation of phosphorylation GO:0042326 57 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
Fly
reactive nitrogen species metabolic process GO:2001057 1 0.011
secretion by cell GO:0032940 248 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.010
response to external biotic stimulus GO:0043207 221 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
circadian regulation of gene expression GO:0032922 3 0.010
ion homeostasis GO:0050801 212 0.010
response to carbohydrate GO:0009743 183 0.010
developmental growth GO:0048589 100 0.010
Fly
carbohydrate metabolic process GO:0005975 130 0.010
regulation of kinase activity GO:0043549 117 0.010
Fly
regulation of anatomical structure size GO:0090066 135 0.010
reproductive structure development GO:0048608 128 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
negative regulation of transport GO:0051051 136 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
Mouse

Cyth2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.011