Rattus norvegicus

0 known processes

Tbx1

T-box 1

Tbx1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.155
regulation of nucleic acid templated transcription GO:1903506 380 0.125
Human Rat Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.124
Human Fly
cellular amino acid metabolic process GO:0006520 107 0.117
regulation of transcription dna templated GO:0006355 374 0.110
Human Rat Fly
tissue development GO:0009888 252 0.105
nucleic acid templated transcription GO:0097659 379 0.102
Human Rat Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.094
Rat
carboxylic acid metabolic process GO:0019752 289 0.086
reproductive process GO:0022414 372 0.085
organic acid metabolic process GO:0006082 292 0.082
central nervous system development GO:0007417 311 0.080
positive regulation of cell proliferation GO:0008284 249 0.078
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.074
Human Fly
positive regulation of biosynthetic process GO:0009891 319 0.074
Human Fly
negative regulation of metabolic process GO:0009892 331 0.073
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.070
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.069
regulation of rna biosynthetic process GO:2001141 381 0.067
Human Rat Fly
anterior posterior pattern specification GO:0009952 1 0.064
cellular component movement GO:0006928 248 0.063
rna biosynthetic process GO:0032774 380 0.063
Human Rat Fly
transcription dna templated GO:0006351 377 0.063
Human Rat Fly
negative regulation of ion transport GO:0043271 51 0.059
regulation of ion transport GO:0043269 245 0.058
response to other organism GO:0051707 220 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
Human Fly
carbohydrate derivative metabolic process GO:1901135 346 0.053
regulation of molecular function GO:0065009 398 0.052
neuron differentiation GO:0030182 368 0.052
negative regulation of cell death GO:0060548 229 0.050
Rat
single organism biosynthetic process GO:0044711 342 0.048
amine metabolic process GO:0009308 38 0.046
brain development GO:0007420 247 0.046
head development GO:0060322 247 0.045
programmed cell death GO:0012501 392 0.045
Rat
rna metabolic process GO:0016070 406 0.041
Human Rat Fly
single organism reproductive process GO:0044702 297 0.041
cell part morphogenesis GO:0032990 123 0.040
apoptotic process GO:0006915 381 0.039
Rat
regulation of rna metabolic process GO:0051252 391 0.039
Human Rat Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.039
cellular ketone metabolic process GO:0042180 51 0.038
carboxylic acid transport GO:0046942 115 0.037
monocarboxylic acid metabolic process GO:0032787 152 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.036
Rat Fly
cellular amine metabolic process GO:0044106 38 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
cell cell signaling GO:0007267 335 0.035
single organism intracellular transport GO:1902582 166 0.035
cell projection organization GO:0030030 302 0.034
regulation of metal ion transport GO:0010959 118 0.033
negative regulation of gene expression GO:0010629 199 0.031
Rat
fatty acid metabolic process GO:0006631 99 0.031
retina development in camera type eye GO:0060041 27 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.031
Human Fly
regulation of neurogenesis GO:0050767 247 0.031
negative regulation of biosynthetic process GO:0009890 168 0.030
Rat
negative regulation of molecular function GO:0044092 133 0.030
positive regulation of rna metabolic process GO:0051254 203 0.029
Human Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.029
positive regulation of transcription dna templated GO:0045893 197 0.028
Human Fly
anion transport GO:0006820 178 0.028
ribonucleotide metabolic process GO:0009259 231 0.027
rhythmic process GO:0048511 156 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
negative regulation of amine transport GO:0051953 24 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
epithelium development GO:0060429 96 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
Rat
organic acid transport GO:0015849 116 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
cellular chemical homeostasis GO:0055082 247 0.025
multi organism reproductive process GO:0044703 262 0.025
regulation of apoptotic process GO:0042981 335 0.025
Rat
cellular metal ion homeostasis GO:0006875 172 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
Human Fly
secretion GO:0046903 307 0.024
regulation of cell proliferation GO:0042127 359 0.024
development of primary sexual characteristics GO:0045137 107 0.024
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
male sex differentiation GO:0046661 64 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
Rat
positive regulation of developmental process GO:0051094 283 0.023
regulation of neuron death GO:1901214 115 0.023
cellular ion homeostasis GO:0006873 184 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
Rat
smooth muscle cell proliferation GO:0048659 77 0.022
response to lipopolysaccharide GO:0032496 191 0.022
gland development GO:0048732 155 0.021
Human
regulation of locomotion GO:0040012 148 0.021
neuron projection development GO:0031175 273 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
Rat
cellular response to growth factor stimulus GO:0071363 162 0.021
alcohol metabolic process GO:0006066 77 0.021
response to nutrient levels GO:0031667 370 0.021
eye morphogenesis GO:0048592 4 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.020
regulation of phosphorylation GO:0042325 248 0.020
intracellular transport GO:0046907 185 0.020
transmembrane transport GO:0055085 412 0.020
cation homeostasis GO:0055080 195 0.020
homeostatic process GO:0042592 331 0.020
protein phosphorylation GO:0006468 345 0.019
response to nutrient GO:0007584 248 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
response to ethanol GO:0045471 162 0.019
dna metabolic process GO:0006259 96 0.019
reproduction GO:0000003 245 0.019
developmental process involved in reproduction GO:0003006 159 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
regulation of hormone levels GO:0010817 187 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
cell motility GO:0048870 202 0.018
reproductive system development GO:0061458 128 0.018
cellular homeostasis GO:0019725 252 0.018
cellular cation homeostasis GO:0030003 180 0.018
response to external biotic stimulus GO:0043207 221 0.018
gonad development GO:0008406 104 0.018
myeloid leukocyte differentiation GO:0002573 20 0.018
embryonic pattern specification GO:0009880 1 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
camera type eye development GO:0043010 48 0.017
hematopoietic or lymphoid organ development GO:0048534 36 0.017
Human
ribose phosphate metabolic process GO:0019693 235 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
female pregnancy GO:0007565 122 0.017
response to retinoic acid GO:0032526 63 0.017
Rat
response to wounding GO:0009611 254 0.017
positive regulation of transport GO:0051050 245 0.017
nucleotide metabolic process GO:0009117 279 0.017
multicellular organism reproduction GO:0032504 233 0.017
metal ion transport GO:0030001 289 0.017
organophosphate metabolic process GO:0019637 370 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
hormone metabolic process GO:0042445 69 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
response to cytokine GO:0034097 215 0.016
cellular response to lipid GO:0071396 201 0.016
Rat
chemical homeostasis GO:0048878 292 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
nucleoside metabolic process GO:0009116 179 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
regulation of neuron differentiation GO:0045664 208 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
cell projection morphogenesis GO:0048858 123 0.016
cytoplasmic transport GO:0016482 115 0.016
negative regulation of signal transduction GO:0009968 83 0.015
regulation of secretion GO:0051046 224 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
regulation of cell differentiation GO:0045595 320 0.015
inflammatory response GO:0006954 150 0.015
calcium ion transport GO:0006816 131 0.015
cell type specific apoptotic process GO:0097285 134 0.015
sensory organ development GO:0007423 74 0.015
male gonad development GO:0008584 59 0.015
amide transport GO:0042886 105 0.015
lipid storage GO:0019915 1 0.015
metal ion homeostasis GO:0055065 186 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
axis specification GO:0009798 4 0.014
organelle organization GO:0006996 266 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
Rat Fly
divalent inorganic cation homeostasis GO:0072507 165 0.014
negative regulation of transport GO:0051051 136 0.014
intracellular signal transduction GO:0035556 314 0.014
multicellular organismal signaling GO:0035637 44 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
myeloid cell differentiation GO:0030099 22 0.014
response to acid chemical GO:0001101 222 0.014
Rat
neuron death GO:0070997 127 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
Human Fly
regulation of nervous system development GO:0051960 264 0.014
transmission of nerve impulse GO:0019226 42 0.014
positive regulation of molecular function GO:0044093 230 0.013
regeneration GO:0031099 163 0.013
neuron development GO:0048666 286 0.013
urogenital system development GO:0001655 78 0.013
retinal ganglion cell axon guidance GO:0031290 1 0.013
purine containing compound metabolic process GO:0072521 253 0.013
neuronal action potential GO:0019228 35 0.013
localization of cell GO:0051674 202 0.013
protein processing GO:0016485 68 0.013
cellular response to corticosteroid stimulus GO:0071384 69 0.013
cation transport GO:0006812 382 0.013
regulation of cell development GO:0060284 263 0.013
cellular lipid metabolic process GO:0044255 208 0.013
taxis GO:0042330 67 0.013
calcium ion import GO:0070509 22 0.013
hormone transport GO:0009914 121 0.013
action potential GO:0001508 54 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
immune system development GO:0002520 41 0.013
Human
inorganic ion transmembrane transport GO:0098660 229 0.013
response to estradiol GO:0032355 164 0.013
divalent metal ion transport GO:0070838 132 0.013
lipid metabolic process GO:0006629 283 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
regulation of signal transduction GO:0009966 318 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
positive regulation of cell communication GO:0010647 271 0.012
response to hexose GO:0009746 144 0.012
divalent inorganic cation transport GO:0072511 134 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
eye development GO:0001654 50 0.012
response to glucose GO:0009749 136 0.012
hormone secretion GO:0046879 115 0.012
epithelial cell differentiation GO:0030855 71 0.012
peptidyl amino acid modification GO:0018193 126 0.012
leukocyte activation GO:0045321 76 0.012
response to growth factor GO:0070848 189 0.012
macromolecular complex assembly GO:0065003 273 0.012
locomotion GO:0040011 237 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
response to temperature stimulus GO:0009266 94 0.012
regulation of neuron projection development GO:0010975 161 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
Rat
positive regulation of gene expression GO:0010628 244 0.012
Human Fly
regulation of programmed cell death GO:0043067 341 0.012
Rat
response to biotic stimulus GO:0009607 226 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
chemotaxis GO:0006935 66 0.012
monovalent inorganic cation transport GO:0015672 172 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
reproductive structure development GO:0048608 128 0.011
regulation of catalytic activity GO:0050790 304 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
Fly
positive regulation of signaling GO:0023056 270 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
sex differentiation GO:0007548 113 0.011
regulation of calcium ion transport GO:0051924 77 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to fatty acid GO:0070542 65 0.011
forebrain development GO:0030900 98 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of intracellular transport GO:0032386 65 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
Rat
response to hypoxia GO:0001666 231 0.011
negative regulation of secretion GO:0051048 82 0.011
macromolecule localization GO:0033036 252 0.011
regulation of hydrolase activity GO:0051336 143 0.011
second messenger mediated signaling GO:0019932 51 0.011
regulation of receptor activity GO:0010469 29 0.010
regulation of protein metabolic process GO:0051246 289 0.010
ion homeostasis GO:0050801 212 0.010
cellular response to stress GO:0033554 269 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
cell migration GO:0016477 197 0.010
response to bacterium GO:0009617 200 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
cell morphogenesis GO:0000902 142 0.010
calcium ion homeostasis GO:0055074 162 0.010

Tbx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.037
disease of anatomical entity DOID:7 0 0.037
Human
nervous system disease DOID:863 0 0.037
eye and adnexa disease DOID:1492 0 0.027
eye disease DOID:5614 0 0.024
disease of metabolism DOID:0014667 0 0.016