Rattus norvegicus

9 known processes

Tbx5

T-box 5

Tbx5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.121
Human Rat
reproductive process GO:0022414 372 0.076
positive regulation of biosynthetic process GO:0009891 319 0.074
Human
carboxylic acid metabolic process GO:0019752 289 0.068
g protein coupled receptor signaling pathway GO:0007186 242 0.065
cell cell signaling GO:0007267 335 0.065
Human
regulation of cell proliferation GO:0042127 359 0.059
Human
cellular homeostasis GO:0019725 252 0.058
response to hypoxia GO:0001666 231 0.057
positive regulation of cell communication GO:0010647 271 0.055
positive regulation of gene expression GO:0010628 244 0.054
Human
cellular component movement GO:0006928 248 0.051
Human
regulation of programmed cell death GO:0043067 341 0.050
Rat
central nervous system development GO:0007417 311 0.050
nucleic acid templated transcription GO:0097659 379 0.049
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
Human
positive regulation of developmental process GO:0051094 283 0.049
Human
rna metabolic process GO:0016070 406 0.048
Human Rat
regulation of neurogenesis GO:0050767 247 0.048
positive regulation of cell differentiation GO:0045597 217 0.048
Human
regulation of rna metabolic process GO:0051252 391 0.048
Human Rat
regulation of rna biosynthetic process GO:2001141 381 0.048
Human Rat
regulation of nervous system development GO:0051960 264 0.047
intracellular signal transduction GO:0035556 314 0.047
rna biosynthetic process GO:0032774 380 0.047
Human Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
Human
neurological system process GO:0050877 219 0.045
cellular response to oxygen containing compound GO:1901701 386 0.044
Rat
transcription dna templated GO:0006351 377 0.044
Human Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.044
cellular component assembly GO:0022607 360 0.043
response to inorganic substance GO:0010035 377 0.042
neuron differentiation GO:0030182 368 0.042
oxoacid metabolic process GO:0043436 290 0.042
cation transport GO:0006812 382 0.041
single organism reproductive process GO:0044702 297 0.041
brain development GO:0007420 247 0.041
cellular ion homeostasis GO:0006873 184 0.039
response to oxygen levels GO:0070482 265 0.039
response to decreased oxygen levels GO:0036293 237 0.038
multicellular organismal reproductive process GO:0048609 233 0.038
anatomical structure morphogenesis GO:0009653 298 0.036
Human
organelle organization GO:0006996 266 0.036
regulation of transcription dna templated GO:0006355 374 0.036
Human Rat
positive regulation of transport GO:0051050 245 0.036
cell projection organization GO:0030030 302 0.036
regulation of cell differentiation GO:0045595 320 0.036
Human
regulation of cellular component organization GO:0051128 368 0.036
response to extracellular stimulus GO:0009991 380 0.036
programmed cell death GO:0012501 392 0.035
Human Rat
reproduction GO:0000003 245 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
regulation of cell development GO:0060284 263 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.035
Human
divalent inorganic cation homeostasis GO:0072507 165 0.035
negative regulation of cell death GO:0060548 229 0.034
Rat
multi organism reproductive process GO:0044703 262 0.034
aging GO:0007568 241 0.033
homeostatic process GO:0042592 331 0.033
oxidation reduction process GO:0055114 304 0.033
cellular response to lipid GO:0071396 201 0.033
Rat
cellular metal ion homeostasis GO:0006875 172 0.032
cation homeostasis GO:0055080 195 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
Human Rat
positive regulation of cellular component organization GO:0051130 200 0.031
response to lipopolysaccharide GO:0032496 191 0.031
regulation of catalytic activity GO:0050790 304 0.031
regulation of neuron differentiation GO:0045664 208 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
Human
signal transduction by phosphorylation GO:0023014 144 0.030
positive regulation of cell development GO:0010720 176 0.030
response to other organism GO:0051707 220 0.030
response to biotic stimulus GO:0009607 226 0.030
regulation of secretion by cell GO:1903530 208 0.030
regulation of cellular component movement GO:0051270 150 0.030
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
Rat
head development GO:0060322 247 0.029
mapk cascade GO:0000165 140 0.029
cellular cation homeostasis GO:0030003 180 0.029
cellular amino acid metabolic process GO:0006520 107 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
Human Rat
response to molecule of bacterial origin GO:0002237 194 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
Human
developmental process involved in reproduction GO:0003006 159 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
response to toxic substance GO:0009636 133 0.027
negative regulation of metabolic process GO:0009892 331 0.027
Rat
cellular response to stress GO:0033554 269 0.027
organic acid metabolic process GO:0006082 292 0.027
positive regulation of nervous system development GO:0051962 178 0.027
regulation of behavior GO:0050795 61 0.027
neuron projection development GO:0031175 273 0.027
regulation of cellular localization GO:0060341 263 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
transmembrane transport GO:0055085 412 0.027
response to external biotic stimulus GO:0043207 221 0.026
secretion by cell GO:0032940 248 0.026
multicellular organism reproduction GO:0032504 233 0.026
regulation of secretion GO:0051046 224 0.026
gland development GO:0048732 155 0.025
response to wounding GO:0009611 254 0.025
metal ion transport GO:0030001 289 0.025
calcium ion homeostasis GO:0055074 162 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of protein metabolic process GO:0051246 289 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of signaling GO:0023056 270 0.025
catabolic process GO:0009056 351 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
Rat
biological adhesion GO:0022610 110 0.024
response to ketone GO:1901654 182 0.024
metal ion homeostasis GO:0055065 186 0.024
protein phosphorylation GO:0006468 345 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
Rat
cellular response to organic cyclic compound GO:0071407 202 0.024
regulation of signal transduction GO:0009966 318 0.024
localization of cell GO:0051674 202 0.024
Human
positive regulation of rna metabolic process GO:0051254 203 0.024
Human
negative regulation of transcription dna templated GO:0045892 116 0.024
Rat
positive regulation of signal transduction GO:0009967 175 0.024
response to mechanical stimulus GO:0009612 134 0.023
regulation of hormone levels GO:0010817 187 0.023
ion transmembrane transport GO:0034220 365 0.023
taxis GO:0042330 67 0.023
response to nutrient levels GO:0031667 370 0.023
negative regulation of signaling GO:0023057 157 0.023
cell migration GO:0016477 197 0.023
Human
negative regulation of multicellular organismal process GO:0051241 203 0.023
Human
cellular calcium ion homeostasis GO:0006874 160 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
secretion GO:0046903 307 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
Human
divalent metal ion transport GO:0070838 132 0.023
neuron development GO:0048666 286 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
amine metabolic process GO:0009308 38 0.022
negative regulation of gene expression GO:0010629 199 0.022
Rat
multi multicellular organism process GO:0044706 138 0.022
cellular amine metabolic process GO:0044106 38 0.022
male sex differentiation GO:0046661 64 0.022
ion homeostasis GO:0050801 212 0.022
defense response GO:0006952 194 0.022
chemical homeostasis GO:0048878 292 0.021
sexual reproduction GO:0019953 148 0.021
response to peptide hormone GO:0043434 278 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
nitrogen compound transport GO:0071705 229 0.021
regulation of response to external stimulus GO:0032101 106 0.021
response to estrogen GO:0043627 232 0.021
divalent inorganic cation transport GO:0072511 134 0.021
cellular catabolic process GO:0044248 295 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.020
Rat
immune system process GO:0002376 204 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
vesicle mediated transport GO:0016192 181 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
response to cytokine GO:0034097 215 0.020
protein complex assembly GO:0006461 263 0.020
cellular lipid metabolic process GO:0044255 208 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
cellular glucan metabolic process GO:0006073 23 0.020
cellular component biogenesis GO:0044085 368 0.020
negative regulation of cell communication GO:0010648 158 0.020
calcium ion transport GO:0006816 131 0.020
response to bacterium GO:0009617 200 0.020
synaptic transmission GO:0007268 235 0.020
regulation of neuron projection development GO:0010975 161 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
positive regulation of phosphorylation GO:0042327 177 0.019
regulation of synaptic transmission GO:0050804 141 0.019
regulation of chemotaxis GO:0050920 29 0.019
positive regulation of locomotion GO:0040017 102 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
reproductive system development GO:0061458 128 0.019
apoptotic process GO:0006915 381 0.019
Human Rat
positive regulation of transcription dna templated GO:0045893 197 0.019
Human
regulation of cell projection organization GO:0031344 175 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of secretion GO:0051047 140 0.019
regulation of molecular function GO:0065009 398 0.019
cellular response to external stimulus GO:0071496 118 0.019
response to peptide GO:1901652 292 0.019
protein oligomerization GO:0051259 191 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular ketone metabolic process GO:0042180 51 0.018
tissue development GO:0009888 252 0.018
Human
response to acid chemical GO:0001101 222 0.018
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
Human
response to growth factor GO:0070848 189 0.018
macromolecule localization GO:0033036 252 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
single organism catabolic process GO:0044712 283 0.017
tube development GO:0035295 89 0.017
regulation of neuron death GO:1901214 115 0.017
positive regulation of transferase activity GO:0051347 81 0.017
regulation of system process GO:0044057 208 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
organic substance catabolic process GO:1901575 316 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of response to stress GO:0080134 126 0.017
cell motility GO:0048870 202 0.017
Human
positive regulation of neuron differentiation GO:0045666 126 0.017
lipid metabolic process GO:0006629 283 0.017
behavior GO:0007610 205 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
gastrulation GO:0007369 2 0.017
anterior posterior pattern specification GO:0009952 1 0.017
growth GO:0040007 165 0.017
Human
positive regulation of secretion by cell GO:1903532 128 0.017
regulation of locomotion GO:0040012 148 0.016
Human
endocytosis GO:0006897 84 0.016
cellular protein localization GO:0034613 122 0.016
cell part morphogenesis GO:0032990 123 0.016
positive regulation of cell motility GO:2000147 97 0.016
neuron projection morphogenesis GO:0048812 122 0.016
proteolysis GO:0006508 175 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
cellular chemical homeostasis GO:0055082 247 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
single organism organelle organization GO:1902589 180 0.016
telencephalon development GO:0021537 62 0.016
response to metal ion GO:0010038 253 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
positive regulation of mapk cascade GO:0043410 92 0.015
chemotaxis GO:0006935 66 0.015
response to glucocorticoid GO:0051384 223 0.015
gamete generation GO:0007276 124 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
Rat
forebrain development GO:0030900 98 0.015
nucleotide metabolic process GO:0009117 279 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
cardiovascular system development GO:0072358 134 0.015
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of apoptotic process GO:0042981 335 0.015
Rat
female pregnancy GO:0007565 122 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
Rat
response to corticosteroid GO:0031960 235 0.015
positive regulation of behavior GO:0048520 38 0.015
regulation of protein modification process GO:0031399 194 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of phosphorylation GO:0042325 248 0.015
multicellular organism growth GO:0035264 1 0.015
epithelial cell differentiation GO:0030855 71 0.014
epithelium development GO:0060429 96 0.014
Human
dephosphorylation GO:0016311 98 0.014
nucleoside metabolic process GO:0009116 179 0.014
protein localization GO:0008104 191 0.014
developmental growth GO:0048589 100 0.014
Human
gliogenesis GO:0042063 93 0.014
regulation of transferase activity GO:0051338 123 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
establishment of protein localization GO:0045184 141 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
hormone transport GO:0009914 121 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
Human
purine ribonucleoside metabolic process GO:0046128 168 0.014
cell chemotaxis GO:0060326 31 0.014
cell adhesion GO:0007155 110 0.014
ras protein signal transduction GO:0007265 29 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
glycogen metabolic process GO:0005977 23 0.014
regulation of inflammatory response GO:0050727 48 0.014
protein localization to membrane GO:0072657 36 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of cell death GO:0010942 184 0.014
spermatogenesis GO:0007283 99 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
Rat
purine nucleotide metabolic process GO:0006163 229 0.013
regulation of mapk cascade GO:0043408 116 0.013
purine containing compound metabolic process GO:0072521 253 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Rat
positive regulation of fatty acid beta oxidation GO:0032000 4 0.013
adult locomotory behavior GO:0008344 4 0.013
hormone metabolic process GO:0042445 69 0.013
male gonad development GO:0008584 59 0.013
cell activation GO:0001775 97 0.013
organic anion transport GO:0015711 132 0.013
single organism intracellular transport GO:1902582 166 0.013
negative regulation of response to external stimulus GO:0032102 37 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of defense response GO:0031347 68 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
axis specification GO:0009798 4 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
Rat
carbohydrate metabolic process GO:0005975 130 0.013
regulation of homeostatic process GO:0032844 101 0.013
signal release GO:0023061 145 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
response to nutrient GO:0007584 248 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
response to radiation GO:0009314 137 0.012
blood vessel morphogenesis GO:0048514 58 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
formation of primary germ layer GO:0001704 1 0.012
membrane organization GO:0061024 94 0.012
heart morphogenesis GO:0003007 3 0.012
regulation of hydrolase activity GO:0051336 143 0.012
vascular process in circulatory system GO:0003018 96 0.012
negative regulation of transport GO:0051051 136 0.012
cell growth GO:0016049 104 0.012
response to amino acid GO:0043200 75 0.012
reproductive structure development GO:0048608 128 0.012
cytoplasmic transport GO:0016482 115 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
regulation of peptide transport GO:0090087 87 0.012
angiogenesis GO:0001525 53 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
Rat
generation of precursor metabolites and energy GO:0006091 62 0.012
regulation of hormone secretion GO:0046883 106 0.012
lipid biosynthetic process GO:0008610 128 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
cellular component morphogenesis GO:0032989 155 0.012
purine nucleoside monophosphate catabolic process GO:0009128 55 0.012
anion transport GO:0006820 178 0.012
organophosphate metabolic process GO:0019637 370 0.012
sensory organ development GO:0007423 74 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.012
regulation of catabolic process GO:0009894 113 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
dendrite development GO:0016358 72 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of cell migration GO:0030335 96 0.011
regulation of calcium ion transport GO:0051924 77 0.011
steroid metabolic process GO:0008202 73 0.011
response to ammonium ion GO:0060359 71 0.011
regeneration GO:0031099 163 0.011
response to dexamethasone GO:0071548 49 0.011
male gamete generation GO:0048232 99 0.011
regulation of protein kinase activity GO:0045859 105 0.011
wound healing GO:0042060 122 0.011
aromatic compound catabolic process GO:0019439 168 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
renal system development GO:0072001 67 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
regulation of cell migration GO:0030334 128 0.011
Human
cellular macromolecule localization GO:0070727 122 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
organic acid catabolic process GO:0016054 49 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
neuron death GO:0070997 127 0.011
lymphocyte chemotaxis GO:0048247 3 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of cell motility GO:2000145 131 0.011
Human
organic cyclic compound catabolic process GO:1901361 175 0.011
artery smooth muscle contraction GO:0014824 4 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
circulatory system development GO:0072359 134 0.011
Human
response to alkaloid GO:0043279 132 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of kinase activity GO:0043549 117 0.011
chromosome segregation GO:0007059 2 0.011
cellular response to nutrient levels GO:0031669 60 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
lymphocyte migration GO:0072676 3 0.011
negative regulation of cell development GO:0010721 82 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
single organismal cell cell adhesion GO:0016337 42 0.010
organ morphogenesis GO:0009887 75 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010
cell projection morphogenesis GO:0048858 123 0.010
single organism biosynthetic process GO:0044711 342 0.010
peptide hormone secretion GO:0030072 84 0.010
regulation of homotypic cell cell adhesion GO:0034110 4 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
organ regeneration GO:0031100 101 0.010

Tbx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016