Rattus norvegicus

0 known processes

Rasal2

RAS protein activator like 2

Rasal2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.077
rna biosynthetic process GO:0032774 380 0.063
regulation of phosphate metabolic process GO:0019220 349 0.062
Rat
protein phosphorylation GO:0006468 345 0.058
regulation of transcription dna templated GO:0006355 374 0.055
regulation of cellular component organization GO:0051128 368 0.055
Rat
anatomical structure morphogenesis GO:0009653 298 0.053
purine containing compound metabolic process GO:0072521 253 0.052
Rat
regulation of molecular function GO:0065009 398 0.049
Rat
cellular component movement GO:0006928 248 0.048
cellular component assembly GO:0022607 360 0.043
protein complex subunit organization GO:0071822 302 0.043
negative regulation of cell death GO:0060548 229 0.043
cell motility GO:0048870 202 0.042
ribonucleotide catabolic process GO:0009261 136 0.041
Rat
regulation of apoptotic process GO:0042981 335 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.040
Rat
neuron differentiation GO:0030182 368 0.040
cation transport GO:0006812 382 0.040
regulation of multicellular organismal development GO:2000026 376 0.039
cell morphogenesis involved in differentiation GO:0000904 119 0.038
negative regulation of metabolic process GO:0009892 331 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
programmed cell death GO:0012501 392 0.037
reproductive process GO:0022414 372 0.036
regulation of catalytic activity GO:0050790 304 0.036
Rat
macromolecular complex assembly GO:0065003 273 0.035
neuron development GO:0048666 286 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
Rat
head development GO:0060322 247 0.034
nucleic acid templated transcription GO:0097659 379 0.034
multi organism reproductive process GO:0044703 262 0.034
ribonucleotide metabolic process GO:0009259 231 0.033
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
Rat
regulation of cell differentiation GO:0045595 320 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
Rat
central nervous system development GO:0007417 311 0.032
positive regulation of molecular function GO:0044093 230 0.032
Rat
cell projection morphogenesis GO:0048858 123 0.032
single organism reproductive process GO:0044702 297 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
Rat
multicellular organismal reproductive process GO:0048609 233 0.032
macromolecule localization GO:0033036 252 0.032
cell migration GO:0016477 197 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.031
Rat
organophosphate metabolic process GO:0019637 370 0.031
Rat
regulation of neurogenesis GO:0050767 247 0.031
cell projection organization GO:0030030 302 0.031
regulation of protein modification process GO:0031399 194 0.030
regulation of cell proliferation GO:0042127 359 0.030
amine metabolic process GO:0009308 38 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
positive regulation of developmental process GO:0051094 283 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
nucleobase containing compound catabolic process GO:0034655 152 0.028
Rat
intracellular signal transduction GO:0035556 314 0.028
Rat
regulation of rna metabolic process GO:0051252 391 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
Rat
regulation of programmed cell death GO:0043067 341 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
Rat
cellular amine metabolic process GO:0044106 38 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
Rat
positive regulation of response to stimulus GO:0048584 285 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
transmembrane transport GO:0055085 412 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
brain development GO:0007420 247 0.026
catabolic process GO:0009056 351 0.026
Rat
ribonucleoside metabolic process GO:0009119 174 0.026
Rat
macromolecular complex subunit organization GO:0043933 339 0.026
membrane organization GO:0061024 94 0.025
eye morphogenesis GO:0048592 4 0.025
apoptotic process GO:0006915 381 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
locomotion GO:0040011 237 0.025
cellular response to stress GO:0033554 269 0.025
protein autophosphorylation GO:0046777 66 0.025
peptidyl amino acid modification GO:0018193 126 0.025
aging GO:0007568 241 0.024
transcription dna templated GO:0006351 377 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
localization of cell GO:0051674 202 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
Rat
organelle organization GO:0006996 266 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
neuron projection development GO:0031175 273 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
regulation of hydrolase activity GO:0051336 143 0.024
Rat
cellular amino acid metabolic process GO:0006520 107 0.024
chemical homeostasis GO:0048878 292 0.024
cell part morphogenesis GO:0032990 123 0.024
regulation of nervous system development GO:0051960 264 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
metal ion transport GO:0030001 289 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of cellular localization GO:0060341 263 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
neurological system process GO:0050877 219 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
Rat
response to wounding GO:0009611 254 0.022
purine containing compound catabolic process GO:0072523 138 0.022
Rat
axon development GO:0061564 96 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
cellular ketone metabolic process GO:0042180 51 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
protein complex assembly GO:0006461 263 0.022
intracellular transport GO:0046907 185 0.022
oxoacid metabolic process GO:0043436 290 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
positive regulation of cellular component organization GO:0051130 200 0.021
negative regulation of cell communication GO:0010648 158 0.021
Rat
sexual reproduction GO:0019953 148 0.021
secretion GO:0046903 307 0.021
purine nucleoside metabolic process GO:0042278 169 0.021
Rat
regulation of protein phosphorylation GO:0001932 183 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
Rat
cellular response to lipid GO:0071396 201 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of gene expression GO:0010628 244 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
Rat
cellular component biogenesis GO:0044085 368 0.020
regulation of cell development GO:0060284 263 0.020
regulation of signal transduction GO:0009966 318 0.020
Rat
heterocycle catabolic process GO:0046700 167 0.020
Rat
developmental process involved in reproduction GO:0003006 159 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
reproduction GO:0000003 245 0.020
regulation of protein metabolic process GO:0051246 289 0.020
positive regulation of nervous system development GO:0051962 178 0.019
forebrain development GO:0030900 98 0.019
organic acid metabolic process GO:0006082 292 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
Rat
response to metal ion GO:0010038 253 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
Rat
positive regulation of signaling GO:0023056 270 0.019
positive regulation of signal transduction GO:0009967 175 0.019
cell cell signaling GO:0007267 335 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
cellular component morphogenesis GO:0032989 155 0.018
nucleotide metabolic process GO:0009117 279 0.018
Rat
ras protein signal transduction GO:0007265 29 0.018
Rat
negative regulation of response to stimulus GO:0048585 155 0.018
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
Rat
organic anion transport GO:0015711 132 0.018
protein complex biogenesis GO:0070271 263 0.018
response to biotic stimulus GO:0009607 226 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
neuron projection morphogenesis GO:0048812 122 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
single organism catabolic process GO:0044712 283 0.018
Rat
positive regulation of cell development GO:0010720 176 0.018
positive regulation of cell communication GO:0010647 271 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
Rat
single organism biosynthetic process GO:0044711 342 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.017
regulation of neuron differentiation GO:0045664 208 0.017
aromatic compound catabolic process GO:0019439 168 0.017
Rat
multicellular organism reproduction GO:0032504 233 0.017
gastrulation GO:0007369 2 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
Rat
glycosyl compound catabolic process GO:1901658 126 0.017
Rat
single organism intracellular transport GO:1902582 166 0.017
gamete generation GO:0007276 124 0.017
behavior GO:0007610 205 0.017
cellular chemical homeostasis GO:0055082 247 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
multicellular organism growth GO:0035264 1 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
Rat
organophosphate catabolic process GO:0046434 148 0.016
Rat
ion homeostasis GO:0050801 212 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
Rat
response to extracellular stimulus GO:0009991 380 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
Rat
secretion by cell GO:0032940 248 0.016
response to growth factor GO:0070848 189 0.016
Rat
positive regulation of cell death GO:0010942 184 0.016
single organism behavior GO:0044708 130 0.016
single organism organelle organization GO:1902589 180 0.016
sensory organ development GO:0007423 74 0.016
tissue development GO:0009888 252 0.016
calcium ion transport GO:0006816 131 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
Rat
response to nutrient GO:0007584 248 0.016
synaptic transmission GO:0007268 235 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
taxis GO:0042330 67 0.016
ribonucleoside catabolic process GO:0042454 126 0.015
Rat
positive regulation of neurogenesis GO:0050769 165 0.015
ion transmembrane transport GO:0034220 365 0.015
positive regulation of catabolic process GO:0009896 78 0.015
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.015
mapk cascade GO:0000165 140 0.015
cation homeostasis GO:0055080 195 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
Rat
multicellular organismal signaling GO:0035637 44 0.015
developmental growth GO:0048589 100 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
Rat
regulation of kinase activity GO:0043549 117 0.015
divalent metal ion transport GO:0070838 132 0.015
response to inorganic substance GO:0010035 377 0.015
response to bacterium GO:0009617 200 0.015
circulatory system development GO:0072359 134 0.014
cellular catabolic process GO:0044248 295 0.014
Rat
positive regulation of apoptotic process GO:0043065 154 0.014
metal ion homeostasis GO:0055065 186 0.014
regeneration GO:0031099 163 0.014
proteolysis GO:0006508 175 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of system process GO:0044057 208 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
Rat
positive regulation of catalytic activity GO:0043085 184 0.014
Rat
nucleoside catabolic process GO:0009164 126 0.014
Rat
cellular macromolecular complex assembly GO:0034622 58 0.014
regulation of secretion GO:0051046 224 0.014
transmission of nerve impulse GO:0019226 42 0.014
cellular cation homeostasis GO:0030003 180 0.014
action potential GO:0001508 54 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
Rat
heart morphogenesis GO:0003007 3 0.013
cytoskeleton organization GO:0007010 111 0.013
nitrogen compound transport GO:0071705 229 0.013
cardiovascular system development GO:0072358 134 0.013
calcium ion homeostasis GO:0055074 162 0.013
vesicle mediated transport GO:0016192 181 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
anterior posterior pattern specification GO:0009952 1 0.013
axis specification GO:0009798 4 0.013
cellular macromolecule localization GO:0070727 122 0.013
negative regulation of developmental process GO:0051093 125 0.013
carboxylic acid transport GO:0046942 115 0.013
negative regulation of molecular function GO:0044092 133 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
anion transport GO:0006820 178 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
Rat
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
Rat
maintenance of location GO:0051235 17 0.013
regulation of phosphorylation GO:0042325 248 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
alternative mrna splicing via spliceosome GO:0000380 4 0.013
regulation of hormone levels GO:0010817 187 0.013
ribonucleoside monophosphate catabolic process GO:0009158 55 0.013
cell adhesion GO:0007155 110 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
response to estrogen GO:0043627 232 0.013
response to peptide hormone GO:0043434 278 0.012
organic hydroxy compound transport GO:0015850 77 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
nucleoside metabolic process GO:0009116 179 0.012
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
Rat
embryonic pattern specification GO:0009880 1 0.012
regulation of mapk cascade GO:0043408 116 0.012
cell morphogenesis GO:0000902 142 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
Rat
rho protein signal transduction GO:0007266 11 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
divalent inorganic cation transport GO:0072511 134 0.012
camera type eye morphogenesis GO:0048593 2 0.012
response to oxidative stress GO:0006979 186 0.012
response to decreased oxygen levels GO:0036293 237 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
positive regulation of protein modification process GO:0031401 142 0.012
gonad development GO:0008406 104 0.012
negative regulation of gene expression GO:0010629 199 0.012
gland development GO:0048732 155 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to carbohydrate GO:0009743 183 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
spermatogenesis GO:0007283 99 0.011
lipid storage GO:0019915 1 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
regulation of ion transport GO:0043269 245 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
cytoplasmic transport GO:0016482 115 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of signaling GO:0023057 157 0.011
Rat
reproductive system development GO:0061458 128 0.011
tube development GO:0035295 89 0.011
single organism cellular localization GO:1902580 102 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
response to external biotic stimulus GO:0043207 221 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
Rat
male gamete generation GO:0048232 99 0.011
regulation of neuron projection development GO:0010975 161 0.011
organic substance catabolic process GO:1901575 316 0.011
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
Rat
actin cytoskeleton organization GO:0030036 73 0.011
sex differentiation GO:0007548 113 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
male mating behavior GO:0060179 3 0.011
neuronal action potential GO:0019228 35 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.011
immune system process GO:0002376 204 0.011
growth GO:0040007 165 0.011
Rat
negative regulation of transport GO:0051051 136 0.011
neuromuscular process GO:0050905 2 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
Rat
response to cytokine GO:0034097 215 0.010
regulation of locomotion GO:0040012 148 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
organic acid transport GO:0015849 116 0.010
response to peptide GO:1901652 292 0.010
regulation of cellular component movement GO:0051270 150 0.010
positive regulation of growth GO:0045927 55 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
protein localization GO:0008104 191 0.010
chemosensory behavior GO:0007635 2 0.010
response to acid chemical GO:0001101 222 0.010
circulatory system process GO:0003013 183 0.010
regulation of neuron death GO:1901214 115 0.010
inner ear morphogenesis GO:0042472 1 0.010
nucleotide catabolic process GO:0009166 139 0.010
Rat
gliogenesis GO:0042063 93 0.010
defense response GO:0006952 194 0.010
regulation of secretion by cell GO:1903530 208 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
sequestering of metal ion GO:0051238 9 0.010
regulation of cell projection organization GO:0031344 175 0.010

Rasal2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cardiovascular system disease DOID:1287 0 0.012
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011
disease of cellular proliferation DOID:14566 0 0.010