Rattus norvegicus

0 known processes

Tlk2

tousled-like kinase 2

Tlk2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.241
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.188
transcription from rna polymerase ii promoter GO:0006366 252 0.187
regulation of rna metabolic process GO:0051252 391 0.159
transcription dna templated GO:0006351 377 0.155
intracellular signal transduction GO:0035556 314 0.151
regulation of rna biosynthetic process GO:2001141 381 0.132
rna metabolic process GO:0016070 406 0.121
nucleic acid templated transcription GO:0097659 379 0.118
positive regulation of response to stimulus GO:0048584 285 0.118
positive regulation of gene expression GO:0010628 244 0.117
rna biosynthetic process GO:0032774 380 0.114
positive regulation of signaling GO:0023056 270 0.110
macromolecular complex subunit organization GO:0043933 339 0.096
positive regulation of cell communication GO:0010647 271 0.093
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.083
positive regulation of nucleic acid templated transcription GO:1903508 197 0.083
regulation of nucleic acid templated transcription GO:1903506 380 0.082
protein phosphorylation GO:0006468 345 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.079
regulation of phosphorus metabolic process GO:0051174 349 0.078
regulation of phosphorylation GO:0042325 248 0.077
positive regulation of biosynthetic process GO:0009891 319 0.074
positive regulation of cellular biosynthetic process GO:0031328 295 0.070
cellular component biogenesis GO:0044085 368 0.069
cellular component assembly GO:0022607 360 0.069
programmed cell death GO:0012501 392 0.068
regulation of apoptotic process GO:0042981 335 0.067
positive regulation of phosphorus metabolic process GO:0010562 262 0.064
regulation of cellular component organization GO:0051128 368 0.063
cellular ketone metabolic process GO:0042180 51 0.061
positive regulation of rna metabolic process GO:0051254 203 0.058
positive regulation of phosphate metabolic process GO:0045937 262 0.057
apoptotic process GO:0006915 381 0.057
regulation of phosphate metabolic process GO:0019220 349 0.056
regulation of transforming growth factor beta3 production GO:0032910 2 0.054
negative regulation of nucleic acid templated transcription GO:1903507 117 0.052
amine metabolic process GO:0009308 38 0.052
negative regulation of biosynthetic process GO:0009890 168 0.052
regulation of programmed cell death GO:0043067 341 0.051
metal ion transport GO:0030001 289 0.051
negative regulation of macromolecule metabolic process GO:0010605 260 0.050
macromolecular complex assembly GO:0065003 273 0.049
regulation of cellular amino acid metabolic process GO:0006521 2 0.048
positive regulation of rna biosynthetic process GO:1902680 197 0.047
positive regulation of signal transduction GO:0009967 175 0.047
ras protein signal transduction GO:0007265 29 0.046
positive regulation of transcription dna templated GO:0045893 197 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.045
regulation of protein metabolic process GO:0051246 289 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
organic substance catabolic process GO:1901575 316 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
regulation of protein phosphorylation GO:0001932 183 0.040
positive regulation of phosphorylation GO:0042327 177 0.039
negative regulation of metabolic process GO:0009892 331 0.039
single organism organelle organization GO:1902589 180 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.037
regulation of cell development GO:0060284 263 0.037
positive regulation of cellular component organization GO:0051130 200 0.037
intracellular transport GO:0046907 185 0.036
cation transport GO:0006812 382 0.036
protein autophosphorylation GO:0046777 66 0.036
single organism reproductive process GO:0044702 297 0.036
protein complex biogenesis GO:0070271 263 0.036
carboxylic acid metabolic process GO:0019752 289 0.035
regulation of protein modification process GO:0031399 194 0.033
peptidyl amino acid modification GO:0018193 126 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
organic acid metabolic process GO:0006082 292 0.032
signal transduction by phosphorylation GO:0023014 144 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
regulation of signal transduction GO:0009966 318 0.031
central nervous system development GO:0007417 311 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
positive regulation of apoptotic process GO:0043065 154 0.031
protein complex subunit organization GO:0071822 302 0.031
reproduction GO:0000003 245 0.030
chromosome segregation GO:0007059 2 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
oxoacid metabolic process GO:0043436 290 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
negative regulation of gene expression GO:0010629 199 0.029
cell projection organization GO:0030030 302 0.029
regulation of cell differentiation GO:0045595 320 0.028
nucleocytoplasmic transport GO:0006913 48 0.028
cellular amine metabolic process GO:0044106 38 0.028
positive regulation of molecular function GO:0044093 230 0.028
regulation of cellular localization GO:0060341 263 0.028
regulation of neurogenesis GO:0050767 247 0.028
behavior GO:0007610 205 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of molecular function GO:0065009 398 0.027
reproductive process GO:0022414 372 0.026
proteolysis GO:0006508 175 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
cellular macromolecular complex assembly GO:0034622 58 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
cation transmembrane transport GO:0098655 263 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
defense response GO:0006952 194 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
response to oxygen levels GO:0070482 265 0.024
response to growth factor GO:0070848 189 0.023
response to cytokine GO:0034097 215 0.023
b cell differentiation GO:0030183 2 0.023
regulation of nervous system development GO:0051960 264 0.023
protein complex assembly GO:0006461 263 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
positive regulation of cell death GO:0010942 184 0.023
positive regulation of programmed cell death GO:0043068 157 0.022
neuron differentiation GO:0030182 368 0.022
transmembrane transport GO:0055085 412 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
response to inorganic substance GO:0010035 377 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
neuron projection development GO:0031175 273 0.022
catabolic process GO:0009056 351 0.022
response to biotic stimulus GO:0009607 226 0.022
peptidyl tyrosine phosphorylation GO:0018108 72 0.022
cellular response to oxygen containing compound GO:1901701 386 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
ion transmembrane transport GO:0034220 365 0.021
organelle organization GO:0006996 266 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
response to metal ion GO:0010038 253 0.019
positive regulation of developmental process GO:0051094 283 0.019
cellular catabolic process GO:0044248 295 0.019
actin filament based process GO:0030029 86 0.019
positive regulation of transport GO:0051050 245 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
mapk cascade GO:0000165 140 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
single organism intracellular transport GO:1902582 166 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
chemical homeostasis GO:0048878 292 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
nuclear transport GO:0051169 49 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
cellular chemical homeostasis GO:0055082 247 0.016
response to ethanol GO:0045471 162 0.016
macromolecule localization GO:0033036 252 0.016
positive regulation of protein modification process GO:0031401 142 0.016
lipid metabolic process GO:0006629 283 0.016
cellular response to lipid GO:0071396 201 0.016
cellular response to stress GO:0033554 269 0.016
cell fate determination GO:0001709 2 0.016
homeostatic process GO:0042592 331 0.016
multicellular organism reproduction GO:0032504 233 0.016
cellular response to cytokine stimulus GO:0071345 127 0.015
brain development GO:0007420 247 0.015
multicellular organism growth GO:0035264 1 0.015
immune system process GO:0002376 204 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
negative regulation of molecular function GO:0044092 133 0.015
positive regulation of cytokine production GO:0001819 42 0.015
response to hexose GO:0009746 144 0.014
response to glucose GO:0009749 136 0.014
negative regulation of cell death GO:0060548 229 0.014
cellular component morphogenesis GO:0032989 155 0.014
organophosphate metabolic process GO:0019637 370 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of mapk cascade GO:0043408 116 0.014
dephosphorylation GO:0016311 98 0.014
immune response GO:0006955 104 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cytoplasmic transport GO:0016482 115 0.014
response to toxic substance GO:0009636 133 0.014
calcium ion transport GO:0006816 131 0.014
developmental process involved in reproduction GO:0003006 159 0.014
macromolecule catabolic process GO:0009057 58 0.014
regulation of catalytic activity GO:0050790 304 0.014
negative regulation of cell communication GO:0010648 158 0.014
cellular response to alcohol GO:0097306 87 0.014
protein import into nucleus GO:0006606 35 0.013
response to decreased oxygen levels GO:0036293 237 0.013
regulation of cell projection organization GO:0031344 175 0.013
sexual reproduction GO:0019953 148 0.013
anterior posterior pattern specification GO:0009952 1 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
regulation of cytokine production GO:0001817 56 0.013
response to wounding GO:0009611 254 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of cell development GO:0010720 176 0.013
cell cycle GO:0007049 101 0.013
response to nutrient levels GO:0031667 370 0.013
response to radiation GO:0009314 137 0.013
muscle system process GO:0003012 115 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of hydrolase activity GO:0051336 143 0.012
negative regulation of signaling GO:0023057 157 0.012
neuron development GO:0048666 286 0.012
mrna metabolic process GO:0016071 20 0.012
head development GO:0060322 247 0.012
regulation of transferase activity GO:0051338 123 0.012
response to monosaccharide GO:0034284 159 0.012
aromatic compound catabolic process GO:0019439 168 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of system process GO:0044057 208 0.012
response to estradiol GO:0032355 164 0.012
cellular macromolecule catabolic process GO:0044265 29 0.012
single organism cellular localization GO:1902580 102 0.012
response to external biotic stimulus GO:0043207 221 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
response to estrogen GO:0043627 232 0.011
response to hypoxia GO:0001666 231 0.011
regulation of organelle organization GO:0033043 80 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
divalent inorganic cation transport GO:0072511 134 0.011
spindle organization GO:0007051 2 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
gamete generation GO:0007276 124 0.011
secretion GO:0046903 307 0.011
cell growth GO:0016049 104 0.011
regulation of transmembrane transport GO:0034762 122 0.011
growth GO:0040007 165 0.011
dna metabolic process GO:0006259 96 0.011
cellular protein complex assembly GO:0043623 44 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
divalent metal ion transport GO:0070838 132 0.011
cation homeostasis GO:0055080 195 0.011
carbohydrate metabolic process GO:0005975 130 0.011
lipid modification GO:0030258 52 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
regulation of nucleocytoplasmic transport GO:0046822 28 0.010
axis specification GO:0009798 4 0.010
nitrogen compound transport GO:0071705 229 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
vesicle mediated transport GO:0016192 181 0.010
ion homeostasis GO:0050801 212 0.010
sex differentiation GO:0007548 113 0.010
regulation of ion transmembrane transporter activity GO:0032412 48 0.010
cellular homeostasis GO:0019725 252 0.010
negative regulation of transport GO:0051051 136 0.010

Tlk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org