Rattus norvegicus

43 known processes

Mre11a

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

(Aliases: Mre11)

Mre11a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.094
anatomical structure morphogenesis GO:0009653 298 0.082
cellular component biogenesis GO:0044085 368 0.080
single organism biosynthetic process GO:0044711 342 0.075
single organism reproductive process GO:0044702 297 0.069
organic acid metabolic process GO:0006082 292 0.069
rna metabolic process GO:0016070 406 0.066
secretion GO:0046903 307 0.062
macromolecular complex assembly GO:0065003 273 0.061
vesicle mediated transport GO:0016192 181 0.061
regulation of cellular localization GO:0060341 263 0.059
secretion by cell GO:0032940 248 0.057
multicellular organism reproduction GO:0032504 233 0.056
neuron development GO:0048666 286 0.056
nucleobase containing small molecule metabolic process GO:0055086 316 0.055
reproductive process GO:0022414 372 0.054
regulation of cell differentiation GO:0045595 320 0.053
protein complex assembly GO:0006461 263 0.053
regulation of cellular component organization GO:0051128 368 0.052
regulation of multicellular organismal development GO:2000026 376 0.048
cellular response to stress GO:0033554 269 0.048
cellular component assembly GO:0022607 360 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
oxoacid metabolic process GO:0043436 290 0.048
negative regulation of metabolic process GO:0009892 331 0.048
organophosphate metabolic process GO:0019637 370 0.048
organelle organization GO:0006996 266 0.047
organelle localization GO:0051640 55 0.044
cellular ketone metabolic process GO:0042180 51 0.044
reproduction GO:0000003 245 0.044
regulation of neurogenesis GO:0050767 247 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
regulation of secretion by cell GO:1903530 208 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.041
brain development GO:0007420 247 0.041
tissue development GO:0009888 252 0.041
positive regulation of cell communication GO:0010647 271 0.041
positive regulation of signaling GO:0023056 270 0.040
nucleoside phosphate metabolic process GO:0006753 283 0.039
response to extracellular stimulus GO:0009991 380 0.039
regulation of nervous system development GO:0051960 264 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
intracellular signal transduction GO:0035556 314 0.038
regulation of neuron differentiation GO:0045664 208 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
chromosome segregation GO:0007059 2 0.038
cell cell signaling GO:0007267 335 0.037
single organism cellular localization GO:1902580 102 0.036
single organism catabolic process GO:0044712 283 0.036
response to wounding GO:0009611 254 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
single organism organelle organization GO:1902589 180 0.036
neuron projection development GO:0031175 273 0.034
regulation of signal transduction GO:0009966 318 0.034
multi organism reproductive process GO:0044703 262 0.034
amine metabolic process GO:0009308 38 0.034
apoptotic process GO:0006915 381 0.034
protein complex biogenesis GO:0070271 263 0.033
synaptic transmission GO:0007268 235 0.033
embryonic pattern specification GO:0009880 1 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
developmental process involved in reproduction GO:0003006 159 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
cell projection organization GO:0030030 302 0.032
rhythmic process GO:0048511 156 0.031
establishment of organelle localization GO:0051656 37 0.031
programmed cell death GO:0012501 392 0.031
regulation of apoptotic process GO:0042981 335 0.031
cellular lipid metabolic process GO:0044255 208 0.030
anterior posterior pattern specification GO:0009952 1 0.030
regulation of programmed cell death GO:0043067 341 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.029
response to decreased oxygen levels GO:0036293 237 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
regulation of transcription dna templated GO:0006355 374 0.029
response to peptide GO:1901652 292 0.029
organic substance catabolic process GO:1901575 316 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
regulation of cell projection organization GO:0031344 175 0.029
protein localization GO:0008104 191 0.028
nucleotide metabolic process GO:0009117 279 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of cell development GO:0060284 263 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
response to nutrient levels GO:0031667 370 0.027
protein complex subunit organization GO:0071822 302 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
response to oxidative stress GO:0006979 186 0.027
response to ketone GO:1901654 182 0.027
response to peptide hormone GO:0043434 278 0.027
signal release GO:0023061 145 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
rna biosynthetic process GO:0032774 380 0.026
head development GO:0060322 247 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
protein oligomerization GO:0051259 191 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
gland development GO:0048732 155 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
positive regulation of secretion GO:0051047 140 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
gonad development GO:0008406 104 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
positive regulation of developmental process GO:0051094 283 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
multicellular organism growth GO:0035264 1 0.024
regulation of neuron projection development GO:0010975 161 0.024
cellular amine metabolic process GO:0044106 38 0.024
chemical homeostasis GO:0048878 292 0.024
positive regulation of nervous system development GO:0051962 178 0.023
regulation of secretion GO:0051046 224 0.023
response to oxygen levels GO:0070482 265 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
central nervous system development GO:0007417 311 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
regulation of hormone levels GO:0010817 187 0.022
intracellular transport GO:0046907 185 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
coenzyme metabolic process GO:0006732 86 0.022
nucleic acid templated transcription GO:0097659 379 0.022
cellular macromolecule localization GO:0070727 122 0.021
regulation of molecular function GO:0065009 398 0.021
lipid biosynthetic process GO:0008610 128 0.021
response to estradiol GO:0032355 164 0.021
nitrogen compound transport GO:0071705 229 0.021
cell cycle checkpoint GO:0000075 2 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
neuron apoptotic process GO:0051402 88 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
oxidation reduction process GO:0055114 304 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
response to glucocorticoid GO:0051384 223 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
positive regulation of cell development GO:0010720 176 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
negative regulation of gene expression GO:0010629 199 0.020
cellular chemical homeostasis GO:0055082 247 0.020
neuron projection morphogenesis GO:0048812 122 0.020
gamete generation GO:0007276 124 0.020
negative regulation of developmental process GO:0051093 125 0.019
regulation of protein metabolic process GO:0051246 289 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
protein transport GO:0015031 132 0.019
transcription dna templated GO:0006351 377 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
lipid metabolic process GO:0006629 283 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
axis specification GO:0009798 4 0.019
sexual reproduction GO:0019953 148 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
telencephalon development GO:0021537 62 0.019
positive regulation of molecular function GO:0044093 230 0.019
response to nutrient GO:0007584 248 0.019
single organism intracellular transport GO:1902582 166 0.019
cellular response to endogenous stimulus GO:0071495 377 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
single organism membrane organization GO:0044802 74 0.018
negative regulation of transport GO:0051051 136 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
tube development GO:0035295 89 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
epithelium development GO:0060429 96 0.018
regulation of sister chromatid segregation GO:0033045 1 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
macromolecule localization GO:0033036 252 0.018
response to reactive oxygen species GO:0000302 120 0.018
regulation of synaptic transmission GO:0050804 141 0.017
cellular catabolic process GO:0044248 295 0.017
response to ethanol GO:0045471 162 0.017
regulation of cell proliferation GO:0042127 359 0.017
small molecule biosynthetic process GO:0044283 124 0.017
catabolic process GO:0009056 351 0.017
purine containing compound metabolic process GO:0072521 253 0.017
response to inorganic substance GO:0010035 377 0.017
eye morphogenesis GO:0048592 4 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
metal ion transport GO:0030001 289 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
response to alkaloid GO:0043279 132 0.016
single organism behavior GO:0044708 130 0.016
membrane organization GO:0061024 94 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
small molecule catabolic process GO:0044282 59 0.016
cell cycle GO:0007049 101 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
regulation of locomotion GO:0040012 148 0.016
regulation of membrane potential GO:0042391 110 0.016
dna integrity checkpoint GO:0031570 2 0.015
protein heterooligomerization GO:0051291 89 0.015
synaptic vesicle endocytosis GO:0048488 4 0.015
response to temperature stimulus GO:0009266 94 0.015
mitotic sister chromatid separation GO:0051306 1 0.015
memory GO:0007613 54 0.015
sex differentiation GO:0007548 113 0.015
behavior GO:0007610 205 0.015
cell part morphogenesis GO:0032990 123 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
cellular protein localization GO:0034613 122 0.015
aging GO:0007568 241 0.015
cofactor metabolic process GO:0051186 95 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
response to acid chemical GO:0001101 222 0.015
cytoskeleton dependent cytokinesis GO:0061640 2 0.015
monosaccharide metabolic process GO:0005996 61 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
regulation of mitotic sister chromatid separation GO:0010965 1 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.014
development of primary sexual characteristics GO:0045137 107 0.014
regulation of homeostatic process GO:0032844 101 0.014
regulation of peptide transport GO:0090087 87 0.014
endocytosis GO:0006897 84 0.014
olfactory learning GO:0008355 1 0.014
peptide secretion GO:0002790 86 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
cell adhesion GO:0007155 110 0.014
positive regulation of cell death GO:0010942 184 0.014
dna metabolic process GO:0006259 96 0.014
sulfur compound metabolic process GO:0006790 70 0.014
nucleoside metabolic process GO:0009116 179 0.014
wound healing GO:0042060 122 0.014
peptidyl amino acid modification GO:0018193 126 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
cellular component morphogenesis GO:0032989 155 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
protein targeting GO:0006605 61 0.014
metaphase anaphase transition of cell cycle GO:0044784 1 0.014
response to growth factor GO:0070848 189 0.014
regulation of response to stress GO:0080134 126 0.013
cellular component movement GO:0006928 248 0.013
forebrain development GO:0030900 98 0.013
response to hexose GO:0009746 144 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
response to toxic substance GO:0009636 133 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
hormone secretion GO:0046879 115 0.013
meiotic cell cycle process GO:1903046 3 0.013
alcohol metabolic process GO:0006066 77 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
reproductive system development GO:0061458 128 0.013
exocytosis GO:0006887 60 0.013
organ regeneration GO:0031100 101 0.013
regulation of insulin secretion GO:0050796 65 0.013
regulation of anatomical structure size GO:0090066 135 0.013
biological adhesion GO:0022610 110 0.013
actin filament based process GO:0030029 86 0.013
organophosphate catabolic process GO:0046434 148 0.013
positive regulation of gene expression GO:0010628 244 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
positive regulation of transcription dna templated GO:0045893 197 0.012
reproductive structure development GO:0048608 128 0.012
chromosome organization GO:0051276 36 0.012
cell type specific apoptotic process GO:0097285 134 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
hormone transport GO:0009914 121 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
purine containing compound catabolic process GO:0072523 138 0.012
regulation of phosphorylation GO:0042325 248 0.012
ras protein signal transduction GO:0007265 29 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
establishment of vesicle localization GO:0051650 31 0.012
cytoplasmic transport GO:0016482 115 0.012
negative regulation of nervous system development GO:0051961 79 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
insulin secretion GO:0030073 69 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
regulation of protein transport GO:0051223 68 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
nucleoside catabolic process GO:0009164 126 0.012
amide transport GO:0042886 105 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
response to glucose GO:0009749 136 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of mitotic sister chromatid segregation GO:0033047 1 0.012
digestive system development GO:0055123 41 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
response to heat GO:0009408 60 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
pteridine containing compound metabolic process GO:0042558 14 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
tetrahydrofolate metabolic process GO:0046653 9 0.011
transmembrane transport GO:0055085 412 0.011
regulation of body fluid levels GO:0050878 90 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of growth GO:0040008 105 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
chromosome separation GO:0051304 1 0.011
regulation of dendrite development GO:0050773 59 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
establishment of protein localization to organelle GO:0072594 44 0.011
regulation of exocytosis GO:0017157 37 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
rna localization GO:0006403 4 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
peptide transport GO:0015833 97 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
positive regulation of signal transduction GO:0009967 175 0.011
hexose metabolic process GO:0019318 58 0.011
single organism cell adhesion GO:0098602 46 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.011
regulation of peptide secretion GO:0002791 82 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of cell development GO:0010721 82 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
response to fatty acid GO:0070542 65 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of chromosome segregation GO:0051983 1 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
circulatory system development GO:0072359 134 0.010
mapk cascade GO:0000165 140 0.010
carboxylic acid catabolic process GO:0046395 49 0.010
actin cytoskeleton organization GO:0030036 73 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
spindle organization GO:0007051 2 0.010
response to hypoxia GO:0001666 231 0.010
male gamete generation GO:0048232 99 0.010
response to ammonium ion GO:0060359 71 0.010
response to vitamin GO:0033273 131 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
regulation of hormone secretion GO:0046883 106 0.010
cognition GO:0050890 92 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
lipid storage GO:0019915 1 0.010

Mre11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.022
central nervous system disease DOID:331 0 0.015
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011