Rattus norvegicus

0 known processes

Npas2

neuronal PAS domain protein 2

Npas2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.071
regulation of multicellular organismal development GO:2000026 376 0.071
carboxylic acid metabolic process GO:0019752 289 0.067
transcription dna templated GO:0006351 377 0.067
Human Rat
regulation of rna metabolic process GO:0051252 391 0.064
Human Rat
apoptotic process GO:0006915 381 0.059
oxoacid metabolic process GO:0043436 290 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
Human Rat
regulation of programmed cell death GO:0043067 341 0.054
central nervous system development GO:0007417 311 0.051
organic acid metabolic process GO:0006082 292 0.051
regulation of nervous system development GO:0051960 264 0.050
regulation of cellular ketone metabolic process GO:0010565 27 0.049
cell projection organization GO:0030030 302 0.049
regulation of cell differentiation GO:0045595 320 0.048
cellular ketone metabolic process GO:0042180 51 0.048
regulation of transcription dna templated GO:0006355 374 0.048
Human Rat
anatomical structure morphogenesis GO:0009653 298 0.047
regulation of cellular component organization GO:0051128 368 0.046
cellular amino acid metabolic process GO:0006520 107 0.045
amine metabolic process GO:0009308 38 0.045
regulation of cell development GO:0060284 263 0.044
single organism biosynthetic process GO:0044711 342 0.043
regulation of phosphate metabolic process GO:0019220 349 0.043
nucleic acid templated transcription GO:0097659 379 0.042
Human Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
organic substance catabolic process GO:1901575 316 0.041
neuron projection development GO:0031175 273 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.041
rna biosynthetic process GO:0032774 380 0.040
Human Rat
cellular amine metabolic process GO:0044106 38 0.040
regulation of apoptotic process GO:0042981 335 0.040
rna metabolic process GO:0016070 406 0.039
Human Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.039
Human Rat
positive regulation of cell development GO:0010720 176 0.039
positive regulation of biosynthetic process GO:0009891 319 0.038
Human Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.038
Human Rat
positive regulation of developmental process GO:0051094 283 0.038
positive regulation of gene expression GO:0010628 244 0.038
Human Rat
regulation of neurogenesis GO:0050767 247 0.037
cation transport GO:0006812 382 0.036
response to extracellular stimulus GO:0009991 380 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
cellular catabolic process GO:0044248 295 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
programmed cell death GO:0012501 392 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
Human Rat
regulation of molecular function GO:0065009 398 0.033
regulation of cell projection organization GO:0031344 175 0.033
negative regulation of gene expression GO:0010629 199 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
Human Rat
positive regulation of nervous system development GO:0051962 178 0.032
regulation of signal transduction GO:0009966 318 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
Human Rat
regulation of hormone levels GO:0010817 187 0.032
cell cell signaling GO:0007267 335 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
Human
chemical homeostasis GO:0048878 292 0.031
cell morphogenesis GO:0000902 142 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
nitrogen compound transport GO:0071705 229 0.030
neuron development GO:0048666 286 0.030
regulation of cellular localization GO:0060341 263 0.030
lipid metabolic process GO:0006629 283 0.029
ion transmembrane transport GO:0034220 365 0.029
regulation of catalytic activity GO:0050790 304 0.029
response to nutrient levels GO:0031667 370 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
Human Rat
negative regulation of metabolic process GO:0009892 331 0.028
catabolic process GO:0009056 351 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
cellular response to stress GO:0033554 269 0.028
Human
positive regulation of rna metabolic process GO:0051254 203 0.028
Human Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.028
head development GO:0060322 247 0.027
behavior GO:0007610 205 0.027
protein complex biogenesis GO:0070271 263 0.027
cellular component biogenesis GO:0044085 368 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
Human Rat
secretion GO:0046903 307 0.027
regulation of neuron differentiation GO:0045664 208 0.026
cell part morphogenesis GO:0032990 123 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
carbohydrate metabolic process GO:0005975 130 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
homeostatic process GO:0042592 331 0.026
negative regulation of cell death GO:0060548 229 0.026
Human
negative regulation of multicellular organismal process GO:0051241 203 0.026
positive regulation of transport GO:0051050 245 0.025
single organism catabolic process GO:0044712 283 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
ion homeostasis GO:0050801 212 0.025
protein phosphorylation GO:0006468 345 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
metal ion transport GO:0030001 289 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.024
secretion by cell GO:0032940 248 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
circulatory system development GO:0072359 134 0.024
regulation of cell proliferation GO:0042127 359 0.024
cardiovascular system development GO:0072358 134 0.024
response to growth factor GO:0070848 189 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
Human Rat
positive regulation of neurogenesis GO:0050769 165 0.024
positive regulation of molecular function GO:0044093 230 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
transmembrane transport GO:0055085 412 0.024
organophosphate metabolic process GO:0019637 370 0.024
cellular component assembly GO:0022607 360 0.024
response to biotic stimulus GO:0009607 226 0.024
intracellular signal transduction GO:0035556 314 0.024
cellular lipid metabolic process GO:0044255 208 0.023
regulation of neuron projection development GO:0010975 161 0.023
tissue development GO:0009888 252 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of protein metabolic process GO:0051246 289 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
cellular chemical homeostasis GO:0055082 247 0.023
defense response GO:0006952 194 0.023
regulation of secretion by cell GO:1903530 208 0.022
protein complex assembly GO:0006461 263 0.022
response to nutrient GO:0007584 248 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
negative regulation of developmental process GO:0051093 125 0.022
cellular component movement GO:0006928 248 0.022
positive regulation of cell death GO:0010942 184 0.022
reproduction GO:0000003 245 0.022
proteolysis GO:0006508 175 0.021
brain development GO:0007420 247 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
response to wounding GO:0009611 254 0.021
response to carbohydrate GO:0009743 183 0.021
negative regulation of cell communication GO:0010648 158 0.021
positive regulation of neuron differentiation GO:0045666 126 0.021
multicellular organism reproduction GO:0032504 233 0.021
single organism intracellular transport GO:1902582 166 0.021
signal release GO:0023061 145 0.021
intracellular transport GO:0046907 185 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
fatty acid metabolic process GO:0006631 99 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
axon development GO:0061564 96 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
response to hypoxia GO:0001666 231 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
regulation of catabolic process GO:0009894 113 0.020
protein complex subunit organization GO:0071822 302 0.020
ras protein signal transduction GO:0007265 29 0.020
cation homeostasis GO:0055080 195 0.020
divalent metal ion transport GO:0070838 132 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
single organism reproductive process GO:0044702 297 0.020
lipid biosynthetic process GO:0008610 128 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
cell projection morphogenesis GO:0048858 123 0.019
oxidation reduction process GO:0055114 304 0.019
cellular homeostasis GO:0019725 252 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
Human
response to external biotic stimulus GO:0043207 221 0.019
negative regulation of signaling GO:0023057 157 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
Human
regulation of secretion GO:0051046 224 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
cell growth GO:0016049 104 0.019
regulation of response to stress GO:0080134 126 0.018
Human
reproductive process GO:0022414 372 0.018
single organism behavior GO:0044708 130 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
negative regulation of transport GO:0051051 136 0.018
cellular ion homeostasis GO:0006873 184 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
nucleotide metabolic process GO:0009117 279 0.018
macromolecular complex assembly GO:0065003 273 0.018
gastrulation GO:0007369 2 0.018
negative regulation of nervous system development GO:0051961 79 0.018
protein localization GO:0008104 191 0.018
regulation of phosphorylation GO:0042325 248 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
Human
cell morphogenesis involved in differentiation GO:0000904 119 0.017
response to oxygen levels GO:0070482 265 0.017
multi organism reproductive process GO:0044703 262 0.017
cognition GO:0050890 92 0.017
regulation of peptide transport GO:0090087 87 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
cellular cation homeostasis GO:0030003 180 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
regulation of hormone secretion GO:0046883 106 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to ketone GO:1901654 182 0.017
regulation of cell growth GO:0001558 85 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
response to decreased oxygen levels GO:0036293 237 0.017
response to other organism GO:0051707 220 0.017
amide transport GO:0042886 105 0.017
cellular component morphogenesis GO:0032989 155 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
neuron projection morphogenesis GO:0048812 122 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
neurological system process GO:0050877 219 0.016
regulation of system process GO:0044057 208 0.016
learning or memory GO:0007611 90 0.016
macromolecule localization GO:0033036 252 0.016
locomotion GO:0040011 237 0.016
multicellular organism growth GO:0035264 1 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
hormone secretion GO:0046879 115 0.016
regulation of membrane potential GO:0042391 110 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
peptide transport GO:0015833 97 0.016
response to bacterium GO:0009617 200 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
purine containing compound metabolic process GO:0072521 253 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
establishment of protein localization GO:0045184 141 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of hydrolase activity GO:0051336 143 0.015
chemotaxis GO:0006935 66 0.015
cation transmembrane transport GO:0098655 263 0.015
cytoplasmic transport GO:0016482 115 0.015
localization of cell GO:0051674 202 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
eye morphogenesis GO:0048592 4 0.015
metal ion homeostasis GO:0055065 186 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
negative regulation of cell development GO:0010721 82 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
aging GO:0007568 241 0.014
inflammatory response GO:0006954 150 0.014
heart morphogenesis GO:0003007 3 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
calcium ion transport GO:0006816 131 0.014
heterocycle catabolic process GO:0046700 167 0.014
anion transport GO:0006820 178 0.014
positive regulation of protein modification process GO:0031401 142 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
response to hexose GO:0009746 144 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to monosaccharide GO:0034284 159 0.014
organelle organization GO:0006996 266 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of insulin secretion GO:0050796 65 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
hormone transport GO:0009914 121 0.013
positive regulation of signaling GO:0023056 270 0.013
cell activation GO:0001775 97 0.013
growth GO:0040007 165 0.013
response to cytokine GO:0034097 215 0.013
regeneration GO:0031099 163 0.013
mapk cascade GO:0000165 140 0.013
cell migration GO:0016477 197 0.013
protein transport GO:0015031 132 0.013
single organism organelle organization GO:1902589 180 0.013
gamete generation GO:0007276 124 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
insulin secretion GO:0030073 69 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
peptide hormone secretion GO:0030072 84 0.013
gland development GO:0048732 155 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
response to estrogen GO:0043627 232 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of secretion GO:0051047 140 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
response to peptide GO:1901652 292 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
cell adhesion GO:0007155 110 0.013
cellular response to lipid GO:0071396 201 0.013
dendrite development GO:0016358 72 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of secretion GO:0051048 82 0.013
blood vessel morphogenesis GO:0048514 58 0.013
coenzyme metabolic process GO:0006732 86 0.012
positive regulation of cell communication GO:0010647 271 0.012
chemosensory behavior GO:0007635 2 0.012
divalent inorganic cation transport GO:0072511 134 0.012
peptide secretion GO:0002790 86 0.012
axis specification GO:0009798 4 0.012
aromatic compound catabolic process GO:0019439 168 0.012
organophosphate catabolic process GO:0046434 148 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of anatomical structure size GO:0090066 135 0.012
cellular protein localization GO:0034613 122 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of peptide secretion GO:0002791 82 0.012
synaptic transmission GO:0007268 235 0.012
response to peptide hormone GO:0043434 278 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
multicellular organismal signaling GO:0035637 44 0.012
response to acid chemical GO:0001101 222 0.012
response to glucose GO:0009749 136 0.012
response to inorganic substance GO:0010035 377 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
sexual reproduction GO:0019953 148 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
epithelium development GO:0060429 96 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
response to activity GO:0014823 73 0.012
cofactor metabolic process GO:0051186 95 0.012
regulation of growth GO:0040008 105 0.012
cellular response to peptide GO:1901653 133 0.012
small molecule biosynthetic process GO:0044283 124 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
forebrain development GO:0030900 98 0.012
transmission of nerve impulse GO:0019226 42 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
cellular response to organonitrogen compound GO:0071417 197 0.011
developmental growth GO:0048589 100 0.011
peptidyl amino acid modification GO:0018193 126 0.011
muscle cell proliferation GO:0033002 84 0.011
anterior posterior pattern specification GO:0009952 1 0.011
telencephalon development GO:0021537 62 0.011
taxis GO:0042330 67 0.011
positive regulation of signal transduction GO:0009967 175 0.011
nucleoside metabolic process GO:0009116 179 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
cellular response to external stimulus GO:0071496 118 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
salivary gland development GO:0007431 3 0.011
regulation of mapk cascade GO:0043408 116 0.011
purine containing compound catabolic process GO:0072523 138 0.011
spermatogenesis GO:0007283 99 0.011
axonogenesis GO:0007409 71 0.011
neuronal action potential GO:0019228 35 0.011
regulation of transferase activity GO:0051338 123 0.011
blood vessel development GO:0001568 69 0.011
sodium ion transport GO:0006814 82 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
male gamete generation GO:0048232 99 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of locomotion GO:0040012 148 0.011
response to corticosteroid GO:0031960 235 0.011
lipid storage GO:0019915 1 0.011
response to metal ion GO:0010038 253 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
regulation of metal ion transport GO:0010959 118 0.011
biological adhesion GO:0022610 110 0.011
cell motility GO:0048870 202 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of rna metabolic process GO:0051253 123 0.010
macromolecule catabolic process GO:0009057 58 0.010
rhythmic process GO:0048511 156 0.010
Rat
organic acid biosynthetic process GO:0016053 83 0.010
regulation of homeostatic process GO:0032844 101 0.010
olfactory behavior GO:0042048 2 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
nuclear transport GO:0051169 49 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
embryonic pattern specification GO:0009880 1 0.010
cellular macromolecule localization GO:0070727 122 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
response to vitamin GO:0033273 131 0.010
reproductive structure development GO:0048608 128 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
gliogenesis GO:0042063 93 0.010
memory GO:0007613 54 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
response to estradiol GO:0032355 164 0.010
vasculature development GO:0001944 70 0.010
organ morphogenesis GO:0009887 75 0.010
response to lipopolysaccharide GO:0032496 191 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
protein oligomerization GO:0051259 191 0.010
phospholipid metabolic process GO:0006644 61 0.010
cellular response to insulin stimulus GO:0032869 81 0.010

Npas2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.016
disease of metabolism DOID:0014667 0 0.013
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.011