Rattus norvegicus

0 known processes

Stk3

serine/threonine kinase 3 (STE20 homolog, yeast)

(Aliases: MST2)

Stk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.161
immune system process GO:0002376 204 0.153
Mouse
catabolic process GO:0009056 351 0.125
regulation of cell development GO:0060284 263 0.118
homeostatic process GO:0042592 331 0.116
regulation of nervous system development GO:0051960 264 0.106
anatomical structure morphogenesis GO:0009653 298 0.099
Mouse
neuron differentiation GO:0030182 368 0.096
positive regulation of multicellular organismal process GO:0051240 387 0.091
response to lipopolysaccharide GO:0032496 191 0.088
organelle organization GO:0006996 266 0.087
regulation of multicellular organismal development GO:2000026 376 0.080
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.078
response to mechanical stimulus GO:0009612 134 0.078
cellular response to insulin stimulus GO:0032869 81 0.076
positive regulation of response to stimulus GO:0048584 285 0.074
Mouse
secretion GO:0046903 307 0.073
regulation of neuron differentiation GO:0045664 208 0.069
cell cell signaling GO:0007267 335 0.067
dna metabolic process GO:0006259 96 0.065
cell morphogenesis GO:0000902 142 0.065
immune response GO:0006955 104 0.063
cardiovascular system development GO:0072358 134 0.063
Mouse
regulation of homeostatic process GO:0032844 101 0.059
eye morphogenesis GO:0048592 4 0.059
single organism intracellular transport GO:1902582 166 0.058
cellular catabolic process GO:0044248 295 0.058
negative regulation of signal transduction GO:0009968 83 0.057
Human Mouse
regulation of rna metabolic process GO:0051252 391 0.056
Human
negative regulation of multicellular organismal process GO:0051241 203 0.055
Mouse
cellular component biogenesis GO:0044085 368 0.052
neuron development GO:0048666 286 0.051
synaptic growth at neuromuscular junction GO:0051124 1 0.050
response to biotic stimulus GO:0009607 226 0.050
nucleotide metabolic process GO:0009117 279 0.050
nitrogen compound transport GO:0071705 229 0.049
regulation of system process GO:0044057 208 0.049
organic acid metabolic process GO:0006082 292 0.048
single organism catabolic process GO:0044712 283 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.047
cellular component movement GO:0006928 248 0.047
intracellular transport GO:0046907 185 0.046
positive regulation of transport GO:0051050 245 0.046
transmembrane transport GO:0055085 412 0.045
blood circulation GO:0008015 183 0.044
proteolysis GO:0006508 175 0.044
neuron projection morphogenesis GO:0048812 122 0.044
response to peptide hormone GO:0043434 278 0.043
brain development GO:0007420 247 0.043
synaptic transmission GO:0007268 235 0.043
regulation of cellular localization GO:0060341 263 0.043
circadian sleep wake cycle process GO:0022410 21 0.042
regulation of cell differentiation GO:0045595 320 0.041
Human
response to external biotic stimulus GO:0043207 221 0.040
programmed cell death GO:0012501 392 0.040
Mouse
macromolecule localization GO:0033036 252 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.040
blood vessel development GO:0001568 69 0.040
positive regulation of cell differentiation GO:0045597 217 0.039
Human
head development GO:0060322 247 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
circulatory system process GO:0003013 183 0.039
rna metabolic process GO:0016070 406 0.039
Human
response to inorganic substance GO:0010035 377 0.038
oxoacid metabolic process GO:0043436 290 0.038
secretion by cell GO:0032940 248 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
ion transmembrane transport GO:0034220 365 0.037
cofactor metabolic process GO:0051186 95 0.037
synapse organization GO:0050808 46 0.037
regulation of neurogenesis GO:0050767 247 0.037
response to toxic substance GO:0009636 133 0.037
positive regulation of cell proliferation GO:0008284 249 0.037
response to oxidative stress GO:0006979 186 0.037
rhythmic behavior GO:0007622 24 0.036
negative regulation of cell death GO:0060548 229 0.036
erythrocyte differentiation GO:0030218 1 0.036
cellular response to peptide GO:1901653 133 0.036
chemical homeostasis GO:0048878 292 0.035
metal ion homeostasis GO:0055065 186 0.035
protein localization GO:0008104 191 0.035
central nervous system development GO:0007417 311 0.035
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
cellular amino acid metabolic process GO:0006520 107 0.034
cation transport GO:0006812 382 0.034
regulation of molecular function GO:0065009 398 0.034
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.034
protein catabolic process GO:0030163 30 0.034
regulation of secretion GO:0051046 224 0.034
nucleic acid templated transcription GO:0097659 379 0.033
Human
regulation of cellular component organization GO:0051128 368 0.033
ion homeostasis GO:0050801 212 0.033
positive regulation of signaling GO:0023056 270 0.033
Mouse
positive regulation of molecular function GO:0044093 230 0.033
Human
response to reactive oxygen species GO:0000302 120 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
cell projection organization GO:0030030 302 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
Human
regulation of cell cycle GO:0051726 73 0.031
circulatory system development GO:0072359 134 0.031
Mouse
positive regulation of developmental process GO:0051094 283 0.031
Human
myeloid cell differentiation GO:0030099 22 0.031
response to oxygen levels GO:0070482 265 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
signal release GO:0023061 145 0.030
cation transmembrane transport GO:0098655 263 0.030
positive regulation of gene expression GO:0010628 244 0.030
single organism reproductive process GO:0044702 297 0.030
Mouse
regulation of membrane potential GO:0042391 110 0.029
locomotion GO:0040011 237 0.029
Worm
purine ribonucleotide metabolic process GO:0009150 227 0.029
apoptotic process GO:0006915 381 0.029
Mouse
rna biosynthetic process GO:0032774 380 0.029
Human
response to other organism GO:0051707 220 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
Mouse
response to insulin GO:0032868 133 0.028
response to bacterium GO:0009617 200 0.028
regulation of intracellular signal transduction GO:1902531 218 0.027
Mouse
establishment of protein localization GO:0045184 141 0.027
protein transport GO:0015031 132 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
neuron projection development GO:0031175 273 0.027
cell part morphogenesis GO:0032990 123 0.026
cellular component assembly GO:0022607 360 0.026
embryonic placenta development GO:0001892 1 0.026
Mouse
response to hydrogen peroxide GO:0042542 89 0.026
vesicle mediated transport GO:0016192 181 0.026
regulation of protein modification process GO:0031399 194 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
response to decreased oxygen levels GO:0036293 237 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.025
Mouse
reproduction GO:0000003 245 0.025
cell projection morphogenesis GO:0048858 123 0.025
regulation of synaptic transmission GO:0050804 141 0.025
negative regulation of growth GO:0045926 37 0.025
Mouse
neural crest cell differentiation GO:0014033 2 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.024
Human
positive regulation of protein metabolic process GO:0051247 178 0.024
regulation of secretion by cell GO:1903530 208 0.024
cellular ion homeostasis GO:0006873 184 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
intracellular signal transduction GO:0035556 314 0.024
Human Mouse
positive regulation of cell communication GO:0010647 271 0.024
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
regulation of protein metabolic process GO:0051246 289 0.024
regulation of response to stress GO:0080134 126 0.024
Mouse
neurological system process GO:0050877 219 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
response to growth factor GO:0070848 189 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
regulation of catalytic activity GO:0050790 304 0.023
cytoplasmic transport GO:0016482 115 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
reproductive process GO:0022414 372 0.023
Mouse
response to cytokine GO:0034097 215 0.023
sensory organ development GO:0007423 74 0.023
Zebrafish
positive regulation of secretion by cell GO:1903532 128 0.022
metal ion transport GO:0030001 289 0.022
coenzyme metabolic process GO:0006732 86 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
response to acid chemical GO:0001101 222 0.022
tube development GO:0035295 89 0.022
Mouse
single organism behavior GO:0044708 130 0.022
neuromuscular synaptic transmission GO:0007274 2 0.022
negative regulation of signaling GO:0023057 157 0.022
Human Mouse
organophosphate metabolic process GO:0019637 370 0.021
positive regulation of cell development GO:0010720 176 0.021
positive regulation of secretion GO:0051047 140 0.021
protein complex biogenesis GO:0070271 263 0.021
eye development GO:0001654 50 0.021
Zebrafish
cytoskeleton organization GO:0007010 111 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
vasculature development GO:0001944 70 0.021
blood vessel morphogenesis GO:0048514 58 0.021
circadian sleep wake cycle sleep GO:0050802 21 0.021
erythrocyte homeostasis GO:0034101 2 0.020
circadian rhythm GO:0007623 88 0.020
protein complex assembly GO:0006461 263 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
immune system development GO:0002520 41 0.020
Mouse
hematopoietic or lymphoid organ development GO:0048534 36 0.020
Mouse
regulation of blood circulation GO:1903522 110 0.020
response to hypoxia GO:0001666 231 0.020
response to wounding GO:0009611 254 0.020
action potential GO:0001508 54 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
protein heterooligomerization GO:0051291 89 0.019
multi multicellular organism process GO:0044706 138 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
cellular chemical homeostasis GO:0055082 247 0.019
cellular response to stress GO:0033554 269 0.019
Mouse
ras protein signal transduction GO:0007265 29 0.019
response to extracellular stimulus GO:0009991 380 0.019
response to estrogen GO:0043627 232 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
olfactory learning GO:0008355 1 0.019
localization of cell GO:0051674 202 0.019
behavior GO:0007610 205 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
Mouse
multi organism reproductive process GO:0044703 262 0.018
regulation of apoptotic process GO:0042981 335 0.018
Mouse
cellular cation homeostasis GO:0030003 180 0.018
regulation of growth GO:0040008 105 0.018
Mouse
response to metal ion GO:0010038 253 0.018
axonogenesis GO:0007409 71 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.018
cation homeostasis GO:0055080 195 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
protein complex subunit organization GO:0071822 302 0.018
cell migration GO:0016477 197 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
axis specification GO:0009798 4 0.018
monovalent inorganic cation transport GO:0015672 172 0.017
developmental growth GO:0048589 100 0.017
Mouse
regulation of cell proliferation GO:0042127 359 0.017
Mouse
negative regulation of cell communication GO:0010648 158 0.017
Human Mouse
regulation of response to external stimulus GO:0032101 106 0.017
response to peptide GO:1901652 292 0.017
negative regulation of metabolic process GO:0009892 331 0.017
regulation of signal transduction GO:0009966 318 0.017
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
developmental process involved in reproduction GO:0003006 159 0.017
Mouse
regulation of mapk cascade GO:0043408 116 0.017
Mouse
cellular response to peptide hormone stimulus GO:0071375 120 0.017
regulation of catabolic process GO:0009894 113 0.017
cellular amine metabolic process GO:0044106 38 0.017
regulation of blood pressure GO:0008217 83 0.017
peptide biosynthetic process GO:0043043 3 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
amine metabolic process GO:0009308 38 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
cellular component morphogenesis GO:0032989 155 0.016
negative regulation of transport GO:0051051 136 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
locomotor rhythm GO:0045475 1 0.016
neural crest cell development GO:0014032 2 0.016
regulation of transcription dna templated GO:0006355 374 0.016
Human
regulation of locomotion GO:0040012 148 0.016
membrane organization GO:0061024 94 0.016
purine containing compound metabolic process GO:0072521 253 0.016
homeostasis of number of cells GO:0048872 10 0.016
cell cycle process GO:0022402 57 0.015
response to purine containing compound GO:0014074 126 0.015
response to nutrient levels GO:0031667 370 0.015
learning or memory GO:0007611 90 0.015
positive regulation of protein modification process GO:0031401 142 0.015
respiratory system development GO:0060541 45 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
chemosensory behavior GO:0007635 2 0.015
regulation of body fluid levels GO:0050878 90 0.015
oxidation reduction process GO:0055114 304 0.015
cellular response to external stimulus GO:0071496 118 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of hormone levels GO:0010817 187 0.015
rhythmic process GO:0048511 156 0.015
positive regulation of immune system process GO:0002684 90 0.015
mapk cascade GO:0000165 140 0.015
Mouse
response to ethanol GO:0045471 162 0.015
protein oligomerization GO:0051259 191 0.015
potassium ion transport GO:0006813 97 0.015
circadian sleep wake cycle GO:0042745 23 0.015
regulation of cellular component movement GO:0051270 150 0.015
response to estradiol GO:0032355 164 0.015
cell motility GO:0048870 202 0.014
renal system process GO:0003014 40 0.014
retina development in camera type eye GO:0060041 27 0.014
hormone transport GO:0009914 121 0.014
rna localization GO:0006403 4 0.014
cellular response to lipid GO:0071396 201 0.014
regulation of anatomical structure size GO:0090066 135 0.014
intracellular receptor signaling pathway GO:0030522 35 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of metal ion transport GO:0010959 118 0.014
forebrain development GO:0030900 98 0.014
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
intracellular protein transport GO:0006886 79 0.014
regulation of ion transport GO:0043269 245 0.014
anterior posterior pattern specification GO:0009952 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
cellular homeostasis GO:0019725 252 0.014
protein maturation GO:0051604 68 0.014
multicellular organism reproduction GO:0032504 233 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
Mouse
mammary gland epithelium development GO:0061180 1 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
regulation of immune system process GO:0002682 123 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
positive regulation of nervous system development GO:0051962 178 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
learning GO:0007612 33 0.013
positive regulation of catabolic process GO:0009896 78 0.013
camera type eye development GO:0043010 48 0.013
Zebrafish
regulation of dendrite morphogenesis GO:0048814 33 0.013
positive regulation of homeostatic process GO:0032846 49 0.013
regulation of transmembrane transport GO:0034762 122 0.013
cognition GO:0050890 92 0.013
gamete generation GO:0007276 124 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
hormone secretion GO:0046879 115 0.013
establishment of organelle localization GO:0051656 37 0.013
inflammatory response GO:0006954 150 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
ovulation cycle GO:0042698 67 0.012
regulation of cell migration GO:0030334 128 0.012
cellular lipid metabolic process GO:0044255 208 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regulation of neuron projection development GO:0010975 161 0.012
cellular amide metabolic process GO:0043603 44 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
microtubule based process GO:0007017 36 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
phospholipid metabolic process GO:0006644 61 0.012
response to radiation GO:0009314 137 0.012
protein phosphorylation GO:0006468 345 0.012
Human Worm
regulation of immune response GO:0050776 55 0.012
single organism biosynthetic process GO:0044711 342 0.012
axon guidance GO:0007411 24 0.012
nucleic acid transport GO:0050657 3 0.012
response to light stimulus GO:0009416 52 0.012
actin cytoskeleton organization GO:0030036 73 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
sexual reproduction GO:0019953 148 0.012
centrosome organization GO:0051297 1 0.011
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
cell cycle GO:0007049 101 0.011
liver development GO:0001889 90 0.011
ossification GO:0001503 70 0.011
negative regulation of nervous system development GO:0051961 79 0.011
response to corticosteroid GO:0031960 235 0.011
single organism cellular localization GO:1902580 102 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 118 0.011
response to ketone GO:1901654 182 0.011
cellular ketone metabolic process GO:0042180 51 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
salivary gland development GO:0007431 3 0.011
skeletal system development GO:0001501 41 0.011
regulation of stem cell proliferation GO:0072091 14 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
Mouse
positive regulation of lipid kinase activity GO:0090218 2 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of ion homeostasis GO:2000021 63 0.011
transmission of nerve impulse GO:0019226 42 0.011
hemopoiesis GO:0030097 34 0.011
Mouse
regulation of vasculature development GO:1901342 44 0.011
cellular macromolecule catabolic process GO:0044265 29 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
calcium ion transport GO:0006816 131 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
regulation of phosphorylation GO:0042325 248 0.011
Mouse
wound healing GO:0042060 122 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
regulation of neuron death GO:1901214 115 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of ion transmembrane transporter activity GO:0032412 48 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
regulation of cell growth GO:0001558 85 0.010
positive regulation of cytokine production GO:0001819 42 0.010
neuron death GO:0070997 127 0.010
defense response GO:0006952 194 0.010
carbohydrate homeostasis GO:0033500 75 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
olfactory behavior GO:0042048 2 0.010

Stk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014