Rattus norvegicus

0 known processes

Serpinb3

serine protease inhibitor B3

Serpinb3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.173
organic acid metabolic process GO:0006082 292 0.153
organic hydroxy compound metabolic process GO:1901615 115 0.141
regulation of cell differentiation GO:0045595 320 0.124
unsaturated fatty acid metabolic process GO:0033559 39 0.114
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.109
negative regulation of chronic inflammatory response GO:0002677 2 0.101
lipid metabolic process GO:0006629 283 0.095
chemical homeostasis GO:0048878 292 0.094
carboxylic acid transport GO:0046942 115 0.090
organic anion transport GO:0015711 132 0.087
response to nutrient levels GO:0031667 370 0.082
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.069
response to inorganic substance GO:0010035 377 0.069
multi organism reproductive process GO:0044703 262 0.067
divalent inorganic cation homeostasis GO:0072507 165 0.064
fatty acid metabolic process GO:0006631 99 0.064
transmembrane transport GO:0055085 412 0.063
positive regulation of transport GO:0051050 245 0.063
response to extracellular stimulus GO:0009991 380 0.062
lipid localization GO:0010876 62 0.061
positive regulation of biosynthetic process GO:0009891 319 0.060
immune system process GO:0002376 204 0.057
anion transport GO:0006820 178 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.055
cell motility GO:0048870 202 0.054
positive regulation of cell proliferation GO:0008284 249 0.053
fatty acid derivative metabolic process GO:1901568 38 0.052
organic acid transport GO:0015849 116 0.051
positive regulation of developmental process GO:0051094 283 0.050
regulation of hormone levels GO:0010817 187 0.050
neurological system process GO:0050877 219 0.050
organelle organization GO:0006996 266 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
response to peptide hormone GO:0043434 278 0.048
oxoacid metabolic process GO:0043436 290 0.048
defense response GO:0006952 194 0.047
negative regulation of response to tumor cell GO:0002835 2 0.046
rna biosynthetic process GO:0032774 380 0.046
cellular calcium ion homeostasis GO:0006874 160 0.046
icosanoid metabolic process GO:0006690 38 0.045
cellular amine metabolic process GO:0044106 38 0.045
cognition GO:0050890 92 0.043
regulation of rna metabolic process GO:0051252 391 0.041
kidney vasculature development GO:0061440 6 0.040
regulation of cell proliferation GO:0042127 359 0.040
response to peptide GO:1901652 292 0.039
response to oxidative stress GO:0006979 186 0.038
locomotion GO:0040011 237 0.038
lipid transport GO:0006869 61 0.038
calcium ion homeostasis GO:0055074 162 0.038
icosanoid biosynthetic process GO:0046456 18 0.037
single organism reproductive process GO:0044702 297 0.037
central nervous system development GO:0007417 311 0.036
monocarboxylic acid metabolic process GO:0032787 152 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
negative regulation of metabolic process GO:0009892 331 0.035
amine metabolic process GO:0009308 38 0.033
ovulation cycle GO:0042698 67 0.032
transforming growth factor beta1 production GO:0032905 2 0.032
glomerular mesangial cell proliferation GO:0072110 4 0.032
sexual reproduction GO:0019953 148 0.032
cellular component assembly GO:0022607 360 0.031
cellular component movement GO:0006928 248 0.031
response to wounding GO:0009611 254 0.030
response to ethanol GO:0045471 162 0.030
cellular response to hormone stimulus GO:0032870 247 0.029
positive regulation of gene expression GO:0010628 244 0.029
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
cytoskeleton organization GO:0007010 111 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
negative regulation of neutrophil apoptotic process GO:0033030 3 0.028
gland development GO:0048732 155 0.028
cellular response to nitrogen compound GO:1901699 210 0.027
negative regulation of gene expression GO:0010629 199 0.027
reproduction GO:0000003 245 0.026
cellular metal ion homeostasis GO:0006875 172 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
secretion GO:0046903 307 0.025
ion transmembrane transport GO:0034220 365 0.024
monocarboxylic acid transport GO:0015718 52 0.024
regulation of phosphorylation GO:0042325 248 0.024
negative regulation of innate immune response GO:0045824 4 0.024
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.024
glomerular mesangium development GO:0072109 4 0.024
tissue development GO:0009888 252 0.024
response to insulin GO:0032868 133 0.024
sensory organ development GO:0007423 74 0.023
micturition GO:0060073 4 0.023
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.023
sodium ion transmembrane transport GO:0035725 67 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of muscle contraction GO:0006937 53 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
cellular lipid metabolic process GO:0044255 208 0.023
reproductive process GO:0022414 372 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
single organism biosynthetic process GO:0044711 342 0.023
gamete generation GO:0007276 124 0.022
cell cycle GO:0007049 101 0.022
protein complex subunit organization GO:0071822 302 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
lipid biosynthetic process GO:0008610 128 0.022
cation transmembrane transport GO:0098655 263 0.022
positive regulation of camp mediated signaling GO:0043950 2 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
alcohol metabolic process GO:0006066 77 0.021
positive regulation of cell communication GO:0010647 271 0.021
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.020
positive regulation of glomerulus development GO:0090193 4 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
response to ketone GO:1901654 182 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
response to vitamin GO:0033273 131 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.019
positive regulation of protein modification process GO:0031401 142 0.019
ovulation cycle process GO:0022602 50 0.019
innate immune response GO:0045087 35 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
cardiovascular system development GO:0072358 134 0.019
angioblast cell migration GO:0035476 1 0.019
phasic smooth muscle contraction GO:0014821 3 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
regulation of cell development GO:0060284 263 0.019
inorganic ion transmembrane transport GO:0098660 229 0.018
rna metabolic process GO:0016070 406 0.018
regulation of signal transduction GO:0009966 318 0.018
leukotriene biosynthetic process GO:0019370 3 0.018
regulation of lipid metabolic process GO:0019216 68 0.018
negative regulation of long term synaptic potentiation GO:1900272 1 0.018
head development GO:0060322 247 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cation transport GO:0006812 382 0.018
sodium ion transport GO:0006814 82 0.018
actin filament based process GO:0030029 86 0.018
leukocyte activation GO:0045321 76 0.017
localization of cell GO:0051674 202 0.017
neuron development GO:0048666 286 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
protein phosphorylation GO:0006468 345 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
brain development GO:0007420 247 0.017
sequestering of metal ion GO:0051238 9 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
epithelial cell proliferation GO:0050673 54 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
response to biotic stimulus GO:0009607 226 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
response to cytokine GO:0034097 215 0.016
cellular response to stress GO:0033554 269 0.016
response to alkaloid GO:0043279 132 0.016
acute inflammatory response GO:0002526 58 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
heart morphogenesis GO:0003007 3 0.015
rhythmic process GO:0048511 156 0.015
metal ion homeostasis GO:0055065 186 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
renal system vasculature development GO:0061437 6 0.015
regulation of actin filament based process GO:0032970 42 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to metal ion GO:0010038 253 0.015
response to toxic substance GO:0009636 133 0.015
cellular component biogenesis GO:0044085 368 0.015
circulatory system development GO:0072359 134 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
regulation of response to stress GO:0080134 126 0.014
renal system development GO:0072001 67 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of lipid biosynthetic process GO:0046889 25 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
lipid storage GO:0019915 1 0.014
kidney development GO:0001822 67 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
regulation of epithelial cell proliferation GO:0050678 49 0.014
macromolecular complex assembly GO:0065003 273 0.014
response to nutrient GO:0007584 248 0.014
neuron differentiation GO:0030182 368 0.014
cellular response to lipid GO:0071396 201 0.014
response to osmotic stress GO:0006970 42 0.014
regulation of nervous system development GO:0051960 264 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
regulation of protein metabolic process GO:0051246 289 0.014
response to bacterium GO:0009617 200 0.013
regulation of immunoglobulin production GO:0002637 4 0.013
negative regulation of immune system process GO:0002683 39 0.013
liver development GO:0001889 90 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
multi multicellular organism process GO:0044706 138 0.013
eosinophil migration GO:0072677 3 0.013
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.013
urinary tract smooth muscle contraction GO:0014848 4 0.013
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.013
cell cell signaling GO:0007267 335 0.013
response to testosterone GO:0033574 55 0.013
eosinophil chemotaxis GO:0048245 3 0.013
ras protein signal transduction GO:0007265 29 0.013
cellular response to oxygen containing compound GO:1901701 386 0.013
fatty acid transport GO:0015908 25 0.013
nucleotide metabolic process GO:0009117 279 0.013
cell migration GO:0016477 197 0.013
erk1 and erk2 cascade GO:0070371 48 0.013
saliva secretion GO:0046541 3 0.013
steroid metabolic process GO:0008202 73 0.013
regulation of transforming growth factor beta1 production GO:0032908 2 0.013
maintenance of location GO:0051235 17 0.013
microglial cell activation GO:0001774 14 0.013
anatomical structure morphogenesis GO:0009653 298 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
negative regulation of cell death GO:0060548 229 0.012
mast cell migration GO:0097531 4 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
smooth muscle contraction involved in micturition GO:0060083 1 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of glomerulus development GO:0090192 4 0.012
gonad development GO:0008406 104 0.012
calcium ion transport GO:0006816 131 0.012
response to calcium ion GO:0051592 59 0.012
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.012
regulation of protein modification process GO:0031399 194 0.012
immune effector process GO:0002252 53 0.012
regulation of neurogenesis GO:0050767 247 0.012
positive regulation of cell development GO:0010720 176 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
cellular component morphogenesis GO:0032989 155 0.012
acid secretion GO:0046717 48 0.012
urogenital system development GO:0001655 78 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.012
transcription dna templated GO:0006351 377 0.012
intracellular transport GO:0046907 185 0.012
cellular response to alcohol GO:0097306 87 0.012
leukocyte cell cell adhesion GO:0007159 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
regulation of mapk cascade GO:0043408 116 0.012
regulation of apoptotic process GO:0042981 335 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of heart contraction GO:0008016 48 0.011
female pregnancy GO:0007565 122 0.011
regulation of innate immune response GO:0045088 15 0.011
regulation of receptor activity GO:0010469 29 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
cation homeostasis GO:0055080 195 0.011
response to external biotic stimulus GO:0043207 221 0.011
regulation of body fluid levels GO:0050878 90 0.011
hepaticobiliary system development GO:0061008 90 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of molecular function GO:0065009 398 0.011
learning or memory GO:0007611 90 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of anatomical structure size GO:0090066 135 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.011
hyperosmotic response GO:0006972 18 0.011
unsaturated fatty acid biosynthetic process GO:0006636 21 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
regulation of vascular permeability GO:0043114 10 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
sensory perception of bitter taste GO:0050913 4 0.011
small molecule catabolic process GO:0044282 59 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
camera type eye development GO:0043010 48 0.011
peristalsis GO:0030432 2 0.011
regulation of behavior GO:0050795 61 0.011
response to camp GO:0051591 91 0.011
biological adhesion GO:0022610 110 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.010
negative regulation of response to biotic stimulus GO:0002832 4 0.010
action potential GO:0001508 54 0.010
catabolic process GO:0009056 351 0.010
fatty acid derivative transport GO:1901571 15 0.010
reproductive structure development GO:0048608 128 0.010
regulation of immune system process GO:0002682 123 0.010
negative regulation of cell communication GO:0010648 158 0.010
response to estrogen GO:0043627 232 0.010
male sex differentiation GO:0046661 64 0.010
positive regulation of camp metabolic process GO:0030816 31 0.010

Serpinb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
integumentary system disease DOID:16 0 0.036
nervous system disease DOID:863 0 0.011