Rattus norvegicus

88 known processes

Serpinb7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

(Aliases: Megsin)

Serpinb7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of metabolic process GO:0009892 331 0.255
Rat
reproductive process GO:0022414 372 0.205
metal ion transport GO:0030001 289 0.162
response to lipopolysaccharide GO:0032496 191 0.135
cellular component movement GO:0006928 248 0.131
sodium ion transport GO:0006814 82 0.131
single organism biosynthetic process GO:0044711 342 0.116
multicellular organismal reproductive process GO:0048609 233 0.101
regulation of cell proliferation GO:0042127 359 0.101
regulation of multicellular organismal development GO:2000026 376 0.099
carboxylic acid metabolic process GO:0019752 289 0.095
multi organism reproductive process GO:0044703 262 0.089
positive regulation of biosynthetic process GO:0009891 319 0.087
regulation of molecular function GO:0065009 398 0.086
Rat
response to external biotic stimulus GO:0043207 221 0.084
cation transport GO:0006812 382 0.084
regulation of nucleic acid templated transcription GO:1903506 380 0.082
positive regulation of cell proliferation GO:0008284 249 0.082
lipid biosynthetic process GO:0008610 128 0.081
inorganic cation transmembrane transport GO:0098662 202 0.079
immune response GO:0006955 104 0.075
growth GO:0040007 165 0.074
rhythmic process GO:0048511 156 0.073
positive regulation of phosphorus metabolic process GO:0010562 262 0.072
organelle organization GO:0006996 266 0.071
reproduction GO:0000003 245 0.070
lipid metabolic process GO:0006629 283 0.068
cation transmembrane transport GO:0098655 263 0.065
positive regulation of developmental process GO:0051094 283 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.064
oxoacid metabolic process GO:0043436 290 0.059
regulation of growth GO:0040008 105 0.058
single organism reproductive process GO:0044702 297 0.058
regulation of programmed cell death GO:0043067 341 0.058
cellular component assembly GO:0022607 360 0.057
rna metabolic process GO:0016070 406 0.057
response to peptide hormone GO:0043434 278 0.056
locomotion GO:0040011 237 0.056
positive regulation of catalytic activity GO:0043085 184 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.055
organic acid metabolic process GO:0006082 292 0.055
immune system process GO:0002376 204 0.054
rna biosynthetic process GO:0032774 380 0.053
behavior GO:0007610 205 0.052
response to oxidative stress GO:0006979 186 0.052
regulation of rna biosynthetic process GO:2001141 381 0.051
positive regulation of response to stimulus GO:0048584 285 0.051
tissue development GO:0009888 252 0.050
negative regulation of apoptotic process GO:0043066 181 0.050
negative regulation of biosynthetic process GO:0009890 168 0.049
response to cytokine GO:0034097 215 0.048
regulation of apoptotic process GO:0042981 335 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.046
Rat
regulation of response to stress GO:0080134 126 0.045
multicellular organism reproduction GO:0032504 233 0.045
response to other organism GO:0051707 220 0.045
intracellular signal transduction GO:0035556 314 0.044
positive regulation of rna metabolic process GO:0051254 203 0.044
cellular response to endogenous stimulus GO:0071495 377 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
ion transmembrane transport GO:0034220 365 0.043
response to estrogen GO:0043627 232 0.043
multi multicellular organism process GO:0044706 138 0.042
regulation of rna metabolic process GO:0051252 391 0.041
cardiovascular system development GO:0072358 134 0.040
sexual reproduction GO:0019953 148 0.040
response to bacterium GO:0009617 200 0.040
epithelial cell differentiation GO:0030855 71 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
positive regulation of cell communication GO:0010647 271 0.039
regulation of cell growth GO:0001558 85 0.039
response to peptide GO:1901652 292 0.039
inorganic ion transmembrane transport GO:0098660 229 0.038
response to molecule of bacterial origin GO:0002237 194 0.038
cellular response to stress GO:0033554 269 0.038
response to insulin GO:0032868 133 0.038
non canonical wnt signaling pathway GO:0035567 3 0.038
regulation of cell differentiation GO:0045595 320 0.038
regulation of cell development GO:0060284 263 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
regulation of cell migration GO:0030334 128 0.037
multicellular organismal homeostasis GO:0048871 49 0.037
regulation of immune system process GO:0002682 123 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
positive regulation of protein metabolic process GO:0051247 178 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
regulation of epithelial cell proliferation GO:0050678 49 0.036
regulation of cell motility GO:2000145 131 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
nucleic acid templated transcription GO:0097659 379 0.035
negative regulation of programmed cell death GO:0043069 183 0.034
regulation of signal transduction GO:0009966 318 0.034
reproductive system development GO:0061458 128 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
regulation of protein metabolic process GO:0051246 289 0.033
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.032
gland development GO:0048732 155 0.032
regulation of lipid metabolic process GO:0019216 68 0.032
circulatory system development GO:0072359 134 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
regulation of neurogenesis GO:0050767 247 0.031
negative regulation of molecular function GO:0044092 133 0.031
Rat
response to reactive oxygen species GO:0000302 120 0.031
positive regulation of immune system process GO:0002684 90 0.030
cell cycle GO:0007049 101 0.030
monovalent inorganic cation transport GO:0015672 172 0.030
regulation of defense response GO:0031347 68 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
localization of cell GO:0051674 202 0.029
steroid metabolic process GO:0008202 73 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
negative regulation of cell death GO:0060548 229 0.029
female pregnancy GO:0007565 122 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
regulation of nervous system development GO:0051960 264 0.029
sex differentiation GO:0007548 113 0.029
single organism behavior GO:0044708 130 0.029
apoptotic process GO:0006915 381 0.029
response to antibiotic GO:0046677 39 0.029
taxis GO:0042330 67 0.028
nucleoside metabolic process GO:0009116 179 0.028
protein phosphorylation GO:0006468 345 0.028
homeostatic process GO:0042592 331 0.028
oxidation reduction process GO:0055114 304 0.028
cellular chemical homeostasis GO:0055082 247 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
negative regulation of vasculature development GO:1901343 11 0.027
single organism organelle organization GO:1902589 180 0.027
development of primary sexual characteristics GO:0045137 107 0.027
regulation of phosphorylation GO:0042325 248 0.026
transmembrane transport GO:0055085 412 0.026
cellular response to lipid GO:0071396 201 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
negative regulation of developmental process GO:0051093 125 0.025
positive regulation of leukocyte proliferation GO:0070665 20 0.025
positive regulation of molecular function GO:0044093 230 0.025
gonad development GO:0008406 104 0.025
developmental induction GO:0031128 2 0.025
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
inflammatory response GO:0006954 150 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
cellular amine metabolic process GO:0044106 38 0.024
response to biotic stimulus GO:0009607 226 0.024
phasic smooth muscle contraction GO:0014821 3 0.024
response to inorganic substance GO:0010035 377 0.024
programmed cell death GO:0012501 392 0.024
cellular ketone metabolic process GO:0042180 51 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.024
amine metabolic process GO:0009308 38 0.023
regulation of metal ion transport GO:0010959 118 0.023
transcription dna templated GO:0006351 377 0.023
regulation of homeostatic process GO:0032844 101 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
epithelium development GO:0060429 96 0.023
brain development GO:0007420 247 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
cell migration GO:0016477 197 0.022
negative regulation of neurogenesis GO:0050768 78 0.022
response to ketone GO:1901654 182 0.022
regulation of cellular component movement GO:0051270 150 0.021
nucleotide metabolic process GO:0009117 279 0.021
jak stat cascade GO:0007259 26 0.021
positive regulation of cell death GO:0010942 184 0.021
response to cold GO:0009409 29 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of leukocyte proliferation GO:0070663 26 0.021
neuron differentiation GO:0030182 368 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
synaptic transmission GO:0007268 235 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
cellular component morphogenesis GO:0032989 155 0.020
defense response GO:0006952 194 0.020
negative regulation of chronic inflammatory response GO:0002677 2 0.020
regulation of immune response to tumor cell GO:0002837 3 0.020
protein heterooligomerization GO:0051291 89 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
retinal metabolic process GO:0042574 3 0.020
reactive nitrogen species metabolic process GO:2001057 1 0.020
protein oligomerization GO:0051259 191 0.020
metal ion homeostasis GO:0055065 186 0.020
peptidyl amino acid modification GO:0018193 126 0.020
response to temperature stimulus GO:0009266 94 0.020
response to acid chemical GO:0001101 222 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
organophosphate metabolic process GO:0019637 370 0.019
neuron death GO:0070997 127 0.019
regulation of membrane potential GO:0042391 110 0.019
positive regulation of gene expression GO:0010628 244 0.019
regulation of reactive oxygen species metabolic process GO:2000377 26 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
regulation of protein kinase activity GO:0045859 105 0.019
regulation of system process GO:0044057 208 0.019
macromolecular complex assembly GO:0065003 273 0.019
ovulation cycle GO:0042698 67 0.019
gamete generation GO:0007276 124 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
saliva secretion GO:0046541 3 0.018
positive regulation of protein modification process GO:0031401 142 0.018
reproductive structure development GO:0048608 128 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
cell cell signaling GO:0007267 335 0.018
cell growth GO:0016049 104 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of ion transport GO:0043269 245 0.018
cation homeostasis GO:0055080 195 0.018
reactive oxygen species metabolic process GO:0072593 37 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
Rat
cellular response to interleukin 1 GO:0071347 37 0.018
head development GO:0060322 247 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.017
cell motility GO:0048870 202 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
regulation of immune response GO:0050776 55 0.017
purine containing compound metabolic process GO:0072521 253 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cell part morphogenesis GO:0032990 123 0.017
regulation of catalytic activity GO:0050790 304 0.017
Rat
positive regulation of cell development GO:0010720 176 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of transferase activity GO:0051338 123 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to radiation GO:0009314 137 0.016
divalent metal ion transport GO:0070838 132 0.016
protein complex assembly GO:0006461 263 0.016
positive regulation of lymphocyte proliferation GO:0050671 20 0.016
positive regulation of signal transduction GO:0009967 175 0.016
neuron development GO:0048666 286 0.016
regulation of transcription dna templated GO:0006355 374 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
male gamete generation GO:0048232 99 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.016
regulation of cell projection organization GO:0031344 175 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
Rat
neuron projection development GO:0031175 273 0.016
hormone biosynthetic process GO:0042446 25 0.016
regulation of vascular permeability GO:0043114 10 0.016
circulatory system process GO:0003013 183 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
regulation of mononuclear cell proliferation GO:0032944 26 0.016
negative regulation of innate immune response GO:0045824 4 0.016
negative regulation of gene expression GO:0010629 199 0.016
Rat
positive regulation of programmed cell death GO:0043068 157 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
protein maturation GO:0051604 68 0.015
Rat
spermatogenesis GO:0007283 99 0.015
alcohol metabolic process GO:0006066 77 0.015
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.015
innate immune response GO:0045087 35 0.015
positive regulation of growth GO:0045927 55 0.015
regulation of organ formation GO:0003156 2 0.015
steroid biosynthetic process GO:0006694 48 0.015
regulation of neuron projection development GO:0010975 161 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
macrophage activation GO:0042116 15 0.015
developmental process involved in reproduction GO:0003006 159 0.015
tissue remodeling GO:0048771 40 0.015
central nervous system development GO:0007417 311 0.015
response to ethanol GO:0045471 162 0.015
proteolysis GO:0006508 175 0.015
Rat
immune response to tumor cell GO:0002418 3 0.014
regulation of vasculature development GO:1901342 44 0.014
sensory perception GO:0007600 101 0.014
response to toxic substance GO:0009636 133 0.014
chemical homeostasis GO:0048878 292 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
negative regulation of cell projection organization GO:0031345 50 0.014
protein complex subunit organization GO:0071822 302 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
blood vessel development GO:0001568 69 0.014
calcium ion homeostasis GO:0055074 162 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
single organism intracellular transport GO:1902582 166 0.013
regulation of sensory perception GO:0051931 29 0.013
cellular ion homeostasis GO:0006873 184 0.013
chemotaxis GO:0006935 66 0.013
regulation of chronic inflammatory response GO:0002676 3 0.013
cell adhesion GO:0007155 110 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
response to tumor cell GO:0002347 4 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of cellular component organization GO:0051128 368 0.013
cytoskeleton organization GO:0007010 111 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
regulation of saliva secretion GO:0046877 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
response to extracellular stimulus GO:0009991 380 0.013
organ morphogenesis GO:0009887 75 0.013
regulation of synaptic transmission GO:0050804 141 0.013
response to purine containing compound GO:0014074 126 0.013
cellular hormone metabolic process GO:0034754 49 0.013
epithelial cell proliferation GO:0050673 54 0.013
positive regulation of cell motility GO:2000147 97 0.013
angioblast cell migration GO:0035476 1 0.013
negative regulation of neuron projection development GO:0010977 46 0.013
leukocyte activation GO:0045321 76 0.012
response to heat GO:0009408 60 0.012
multicellular organism growth GO:0035264 1 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
regulation of lymphocyte activation GO:0051249 34 0.012
hormone metabolic process GO:0042445 69 0.012
response to interleukin 1 GO:0070555 55 0.012
female gonad development GO:0008585 53 0.012
biological adhesion GO:0022610 110 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
angiogenesis GO:0001525 53 0.012
organic hydroxy compound transport GO:0015850 77 0.012
protein complex biogenesis GO:0070271 263 0.012
regulation of cell cycle GO:0051726 73 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.012
response to nutrient levels GO:0031667 370 0.012
lymphocyte migration GO:0072676 3 0.012
regulation of locomotion GO:0040012 148 0.012
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.012
positive regulation of mononuclear cell proliferation GO:0032946 20 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of body fluid levels GO:0050878 90 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
response to transforming growth factor beta GO:0071559 46 0.012
response to decreased oxygen levels GO:0036293 237 0.012
heart development GO:0007507 72 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
acid secretion GO:0046717 48 0.012
tube development GO:0035295 89 0.011
organic substance catabolic process GO:1901575 316 0.011
cellular response to alcohol GO:0097306 87 0.011
positive regulation of epithelial cell proliferation GO:0050679 32 0.011
unsaturated fatty acid metabolic process GO:0033559 39 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
muscle system process GO:0003012 115 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regeneration GO:0031099 163 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
mononuclear cell proliferation GO:0032943 29 0.011
organ formation GO:0048645 3 0.011
response to organophosphorus GO:0046683 102 0.011
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
response to growth factor GO:0070848 189 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of hormone levels GO:0010817 187 0.011
regulation of muscle system process GO:0090257 79 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
dorsal ventral axon guidance GO:0033563 1 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
regulation of proteolysis GO:0030162 66 0.011
Rat
response to starvation GO:0042594 59 0.011
coronary vasculature morphogenesis GO:0060977 3 0.011
negative regulation of cell growth GO:0030308 33 0.011
potassium ion transmembrane transport GO:0071805 71 0.011
organ induction GO:0001759 1 0.011
cellular lipid metabolic process GO:0044255 208 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
ovulation cycle process GO:0022602 50 0.010
kidney development GO:0001822 67 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
Rat
positive regulation of kinase activity GO:0033674 77 0.010
response to glucocorticoid GO:0051384 223 0.010
regulation of neurological system process GO:0031644 43 0.010
salivary gland development GO:0007431 3 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010

Serpinb7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
disease of metabolism DOID:0014667 0 0.018
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.013
inherited metabolic disorder DOID:655 0 0.012