Rattus norvegicus

150 known processes

Tp73

tumor protein p73

(Aliases: P73,Trp73)

Tp73 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.039
Human Rat
regulation of rna biosynthetic process GO:2001141 381 0.039
Human Rat
positive regulation of multicellular organismal process GO:0051240 387 0.038
cellular response to oxygen containing compound GO:1901701 386 0.036
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of cell proliferation GO:0042127 359 0.034
Human Rat
reproductive process GO:0022414 372 0.034
Rat
regulation of cellular component organization GO:0051128 368 0.033
programmed cell death GO:0012501 392 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
Human Rat
response to extracellular stimulus GO:0009991 380 0.032
Rat
rna biosynthetic process GO:0032774 380 0.032
Human Rat
negative regulation of metabolic process GO:0009892 331 0.032
Rat
response to metal ion GO:0010038 253 0.032
Rat
cellular component biogenesis GO:0044085 368 0.031
single organism reproductive process GO:0044702 297 0.031
Rat
multi organism reproductive process GO:0044703 262 0.031
Rat
aging GO:0007568 241 0.031
Rat
response to nutrient levels GO:0031667 370 0.031
Rat
cellular response to stress GO:0033554 269 0.030
Human Rat
cell projection organization GO:0030030 302 0.030
oxoacid metabolic process GO:0043436 290 0.030
reproduction GO:0000003 245 0.030
Rat
rna metabolic process GO:0016070 406 0.029
Human Rat
transcription dna templated GO:0006351 377 0.029
Human Rat
nucleic acid templated transcription GO:0097659 379 0.029
Human Rat
regulation of rna metabolic process GO:0051252 391 0.029
Human Rat
regulation of phosphorus metabolic process GO:0051174 349 0.029
response to peptide GO:1901652 292 0.028
intracellular signal transduction GO:0035556 314 0.028
regulation of neurogenesis GO:0050767 247 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.027
Rat
response to inorganic substance GO:0010035 377 0.027
Rat
chemical homeostasis GO:0048878 292 0.027
Rat
response to oxygen levels GO:0070482 265 0.027
Rat
response to nutrient GO:0007584 248 0.027
Rat
regulation of programmed cell death GO:0043067 341 0.027
neuron differentiation GO:0030182 368 0.027
regulation of protein metabolic process GO:0051246 289 0.027
regulation of apoptotic process GO:0042981 335 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
Human Rat
regulation of nervous system development GO:0051960 264 0.026
response to peptide hormone GO:0043434 278 0.026
response to wounding GO:0009611 254 0.026
Rat
cellular response to endogenous stimulus GO:0071495 377 0.026
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.026
Rat
response to decreased oxygen levels GO:0036293 237 0.026
multicellular organism reproduction GO:0032504 233 0.026
Rat
cellular amino acid metabolic process GO:0006520 107 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
carboxylic acid metabolic process GO:0019752 289 0.025
positive regulation of developmental process GO:0051094 283 0.025
neuron projection development GO:0031175 273 0.025
regulation of cell differentiation GO:0045595 320 0.025
response to bacterium GO:0009617 200 0.025
cellular component assembly GO:0022607 360 0.025
regulation of molecular function GO:0065009 398 0.025
response to hypoxia GO:0001666 231 0.025
regulation of transcription dna templated GO:0006355 374 0.025
Human Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
apoptotic process GO:0006915 381 0.025
regulation of cell development GO:0060284 263 0.025
tissue development GO:0009888 252 0.024
Human
cellular amine metabolic process GO:0044106 38 0.024
macromolecular complex assembly GO:0065003 273 0.024
localization of cell GO:0051674 202 0.024
Rat
neuron development GO:0048666 286 0.024
protein complex subunit organization GO:0071822 302 0.024
cellular response to lipid GO:0071396 201 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
organic acid metabolic process GO:0006082 292 0.023
cellular homeostasis GO:0019725 252 0.023
Rat
protein phosphorylation GO:0006468 345 0.023
brain development GO:0007420 247 0.023
organelle organization GO:0006996 266 0.023
organophosphate metabolic process GO:0019637 370 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
Human Rat
response to estrogen GO:0043627 232 0.023
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of gene expression GO:0010628 244 0.022
Human Rat
positive regulation of cell differentiation GO:0045597 217 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of catalytic activity GO:0050790 304 0.022
cell migration GO:0016477 197 0.022
Rat
anatomical structure morphogenesis GO:0009653 298 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
Human Rat
regulation of system process GO:0044057 208 0.022
homeostatic process GO:0042592 331 0.022
Rat
secretion GO:0046903 307 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Rat
catabolic process GO:0009056 351 0.021
cellular component movement GO:0006928 248 0.021
Rat
amine metabolic process GO:0009308 38 0.021
head development GO:0060322 247 0.021
cellular chemical homeostasis GO:0055082 247 0.021
Rat
neurological system process GO:0050877 219 0.021
protein complex assembly GO:0006461 263 0.021
cation transport GO:0006812 382 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
response to oxidative stress GO:0006979 186 0.021
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.021
transmembrane transport GO:0055085 412 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of neuron differentiation GO:0045664 208 0.021
cellular ion homeostasis GO:0006873 184 0.021
Rat
regulation of phosphate metabolic process GO:0019220 349 0.021
protein complex biogenesis GO:0070271 263 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
Human Rat
response to acid chemical GO:0001101 222 0.020
Rat
circulatory system process GO:0003013 183 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
Human Rat
metal ion transport GO:0030001 289 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
calcium ion homeostasis GO:0055074 162 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
central nervous system development GO:0007417 311 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
ion transmembrane transport GO:0034220 365 0.020
cellular cation homeostasis GO:0030003 180 0.020
Rat
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of signal transduction GO:0009966 318 0.020
anion transport GO:0006820 178 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
negative regulation of gene expression GO:0010629 199 0.019
Rat
locomotion GO:0040011 237 0.019
Rat
growth GO:0040007 165 0.019
Human
cell motility GO:0048870 202 0.019
Rat
blood circulation GO:0008015 183 0.019
ion homeostasis GO:0050801 212 0.019
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.019
response to growth factor GO:0070848 189 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to lipopolysaccharide GO:0032496 191 0.019
response to corticosteroid GO:0031960 235 0.019
negative regulation of cell death GO:0060548 229 0.019
cellular metal ion homeostasis GO:0006875 172 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to external biotic stimulus GO:0043207 221 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
positive regulation of molecular function GO:0044093 230 0.018
response to ethanol GO:0045471 162 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
cell cell signaling GO:0007267 335 0.017
response to other organism GO:0051707 220 0.017
single organism catabolic process GO:0044712 283 0.017
nitrogen compound transport GO:0071705 229 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
response to biotic stimulus GO:0009607 226 0.017
heart morphogenesis GO:0003007 3 0.017
regulation of cellular localization GO:0060341 263 0.017
regulation of phosphorylation GO:0042325 248 0.017
gland development GO:0048732 155 0.017
response to radiation GO:0009314 137 0.017
Rat
positive regulation of neurogenesis GO:0050769 165 0.017
cation transmembrane transport GO:0098655 263 0.017
protein oligomerization GO:0051259 191 0.017
immune system process GO:0002376 204 0.017
Rat
regulation of anatomical structure size GO:0090066 135 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
regulation of cell projection organization GO:0031344 175 0.016
cation homeostasis GO:0055080 195 0.016
Rat
positive regulation of transport GO:0051050 245 0.016
single organism biosynthetic process GO:0044711 342 0.016
multi multicellular organism process GO:0044706 138 0.016
response to glucocorticoid GO:0051384 223 0.016
proteolysis GO:0006508 175 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of developmental process GO:0051093 125 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
cellular catabolic process GO:0044248 295 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
Rat
intracellular transport GO:0046907 185 0.016
regeneration GO:0031099 163 0.016
response to carbohydrate GO:0009743 183 0.016
sexual reproduction GO:0019953 148 0.016
Rat
secretion by cell GO:0032940 248 0.016
regulation of secretion GO:0051046 224 0.016
metal ion homeostasis GO:0055065 186 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
Human Rat
macromolecule localization GO:0033036 252 0.016
ras protein signal transduction GO:0007265 29 0.016
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of cell communication GO:0010647 271 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
Rat
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
Rat
regulation of neuron projection development GO:0010975 161 0.016
cellular response to organic cyclic compound GO:0071407 202 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
Human Rat
behavior GO:0007610 205 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
defense response GO:0006952 194 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
Rat
response to ketone GO:1901654 182 0.015
response to purine containing compound GO:0014074 126 0.015
Rat
cellular response to growth factor stimulus GO:0071363 162 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of hydrolase activity GO:0051336 143 0.015
cell adhesion GO:0007155 110 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Rat
regulation of locomotion GO:0040012 148 0.015
Rat
reproductive structure development GO:0048608 128 0.015
gamete generation GO:0007276 124 0.015
Rat
calcium ion transport GO:0006816 131 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
regulation of protein modification process GO:0031399 194 0.014
epithelium development GO:0060429 96 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
developmental process involved in reproduction GO:0003006 159 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
divalent inorganic cation transport GO:0072511 134 0.014
wound healing GO:0042060 122 0.014
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
regulation of cellular component movement GO:0051270 150 0.014
Rat
regulation of secretion by cell GO:1903530 208 0.014
signal release GO:0023061 145 0.014
axis specification GO:0009798 4 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of signaling GO:0023056 270 0.014
circulatory system development GO:0072359 134 0.014
Human
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.014
Human Rat
divalent metal ion transport GO:0070838 132 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
Rat
purine containing compound metabolic process GO:0072521 253 0.014
sex differentiation GO:0007548 113 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of ion transport GO:0043269 245 0.014
response to estradiol GO:0032355 164 0.014
nucleoside metabolic process GO:0009116 179 0.014
synaptic transmission GO:0007268 235 0.014
response to alkaloid GO:0043279 132 0.014
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
Human Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
Rat
reproductive system development GO:0061458 128 0.013
cellular protein localization GO:0034613 122 0.013
cardiovascular system development GO:0072358 134 0.013
Human
regulation of immune system process GO:0002682 123 0.013
Rat
positive regulation of immune system process GO:0002684 90 0.013
Rat
glycosyl compound metabolic process GO:1901657 182 0.013
response to mechanical stimulus GO:0009612 134 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of cell motility GO:2000145 131 0.013
Rat
neuronal action potential GO:0019228 35 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
lipid metabolic process GO:0006629 283 0.013
action potential GO:0001508 54 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
Human Rat
response to cytokine GO:0034097 215 0.013
Rat
immune response GO:0006955 104 0.013
protein localization GO:0008104 191 0.013
cellular response to external stimulus GO:0071496 118 0.013
response to vitamin GO:0033273 131 0.013
Rat
spermatogenesis GO:0007283 99 0.013
Rat
regulation of hormone levels GO:0010817 187 0.013
organic anion transport GO:0015711 132 0.013
gastrulation GO:0007369 2 0.013
positive regulation of protein modification process GO:0031401 142 0.013
response to hexose GO:0009746 144 0.013
single organism organelle organization GO:1902589 180 0.013
negative regulation of transport GO:0051051 136 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
cellular component morphogenesis GO:0032989 155 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
cell projection morphogenesis GO:0048858 123 0.013
carboxylic acid transport GO:0046942 115 0.012
negative regulation of cell communication GO:0010648 158 0.012
female pregnancy GO:0007565 122 0.012
heterocycle catabolic process GO:0046700 167 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
male gamete generation GO:0048232 99 0.012
Rat
organonitrogen compound catabolic process GO:1901565 179 0.012
cellular response to peptide GO:1901653 133 0.012
single organism intracellular transport GO:1902582 166 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
Rat
positive regulation of locomotion GO:0040017 102 0.012
Rat
cellular response to cytokine stimulus GO:0071345 127 0.012
cell morphogenesis GO:0000902 142 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
negative regulation of molecular function GO:0044092 133 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of blood circulation GO:1903522 110 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
regulation of cell migration GO:0030334 128 0.012
Rat
cell part morphogenesis GO:0032990 123 0.012
biological adhesion GO:0022610 110 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
Human Rat
negative regulation of protein metabolic process GO:0051248 114 0.012
limb morphogenesis GO:0035108 4 0.012
cellular response to acid chemical GO:0071229 75 0.012
establishment of tissue polarity GO:0007164 2 0.012
forebrain development GO:0030900 98 0.012
response to organophosphorus GO:0046683 102 0.012
sensory perception GO:0007600 101 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
sequestering of calcium ion GO:0051208 8 0.011
cell growth GO:0016049 104 0.011
chromosome segregation GO:0007059 2 0.011
cytokine biosynthetic process GO:0042089 3 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
response to reactive oxygen species GO:0000302 120 0.011
transmission of nerve impulse GO:0019226 42 0.011
vascular process in circulatory system GO:0003018 96 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
positive regulation of secretion GO:0051047 140 0.011
dephosphorylation GO:0016311 98 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
muscle system process GO:0003012 115 0.011
sequestering of metal ion GO:0051238 9 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
tube development GO:0035295 89 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
cellular macromolecule localization GO:0070727 122 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
Rat
hormone transport GO:0009914 121 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of tube size GO:0035150 89 0.011
gliogenesis GO:0042063 93 0.011
neuron death GO:0070997 127 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
regulation of synaptic transmission GO:0050804 141 0.011
gonad development GO:0008406 104 0.011
positive regulation of cell motility GO:2000147 97 0.011
Rat
regulation of growth GO:0040008 105 0.011
Human
hormone secretion GO:0046879 115 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of homeostatic process GO:0032844 101 0.011
cell activation GO:0001775 97 0.011
rhythmic process GO:0048511 156 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to toxic substance GO:0009636 133 0.011
appendage morphogenesis GO:0035107 4 0.011
neuron projection morphogenesis GO:0048812 122 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
regulation of neuron death GO:1901214 115 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
organ morphogenesis GO:0009887 75 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
Rat
regulation of response to stress GO:0080134 126 0.011
response to insulin GO:0032868 133 0.011
chemosensory behavior GO:0007635 2 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
response to glucose GO:0009749 136 0.010
nucleotide catabolic process GO:0009166 139 0.010
regulation of body fluid levels GO:0050878 90 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
developmental growth GO:0048589 100 0.010
Human
positive regulation of cell projection organization GO:0031346 111 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
organophosphate catabolic process GO:0046434 148 0.010
regulation of blood vessel size GO:0050880 89 0.010
embryonic pattern specification GO:0009880 1 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
Rat
inorganic cation transmembrane transport GO:0098662 202 0.010
bmp signaling pathway GO:0030509 4 0.010
organic acid transport GO:0015849 116 0.010
negative regulation of signaling GO:0023057 157 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
cellular response to alcohol GO:0097306 87 0.010
oxidation reduction process GO:0055114 304 0.010
epithelial cell differentiation GO:0030855 71 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
coenzyme metabolic process GO:0006732 86 0.010
negative regulation of response to stimulus GO:0048585 155 0.010

Tp73 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.017
sensory system disease DOID:0050155 0 0.016
disease of metabolism DOID:0014667 0 0.014
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.011