Rattus norvegicus

0 known processes

Hrc

histidine rich calcium binding protein

Hrc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle contraction GO:0006941 44 0.243
muscle system process GO:0003012 115 0.166
cellular divalent inorganic cation homeostasis GO:0072503 162 0.115
regulation of programmed cell death GO:0043067 341 0.105
protein localization GO:0008104 191 0.102
calcium ion homeostasis GO:0055074 162 0.100
ion homeostasis GO:0050801 212 0.081
cellular ion homeostasis GO:0006873 184 0.080
cytosolic calcium ion homeostasis GO:0051480 140 0.079
muscle contraction GO:0006936 88 0.078
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.077
cellular catabolic process GO:0044248 295 0.077
muscle structure development GO:0061061 87 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.075
nucleotide metabolic process GO:0009117 279 0.071
macromolecule localization GO:0033036 252 0.069
ribose phosphate metabolic process GO:0019693 235 0.068
divalent inorganic cation transport GO:0072511 134 0.063
organelle organization GO:0006996 266 0.063
single organism reproductive process GO:0044702 297 0.063
regulation of ion transport GO:0043269 245 0.061
cellular component assembly GO:0022607 360 0.061
cellular metal ion homeostasis GO:0006875 172 0.060
nucleoside phosphate metabolic process GO:0006753 283 0.060
macromolecular complex subunit organization GO:0043933 339 0.059
regulation of cellular component movement GO:0051270 150 0.056
cellular macromolecule localization GO:0070727 122 0.054
response to mechanical stimulus GO:0009612 134 0.054
cellular component movement GO:0006928 248 0.053
cellular calcium ion homeostasis GO:0006874 160 0.052
reproductive system development GO:0061458 128 0.052
homeostatic process GO:0042592 331 0.052
metal ion homeostasis GO:0055065 186 0.051
actin mediated cell contraction GO:0070252 12 0.051
protein complex biogenesis GO:0070271 263 0.051
cellular homeostasis GO:0019725 252 0.051
divalent inorganic cation homeostasis GO:0072507 165 0.050
response to ketone GO:1901654 182 0.048
cellular cation homeostasis GO:0030003 180 0.048
regulation of cellular component organization GO:0051128 368 0.048
response to oxygen levels GO:0070482 265 0.047
cellular chemical homeostasis GO:0055082 247 0.047
cellular response to abiotic stimulus GO:0071214 85 0.047
organic substance catabolic process GO:1901575 316 0.046
organophosphate metabolic process GO:0019637 370 0.045
response to carbohydrate GO:0009743 183 0.045
cardiac muscle contraction GO:0060048 27 0.045
cellular protein localization GO:0034613 122 0.045
regulation of cellular localization GO:0060341 263 0.045
response to hydrogen peroxide GO:0042542 89 0.044
response to hypoxia GO:0001666 231 0.044
brain development GO:0007420 247 0.043
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
defense response GO:0006952 194 0.043
proteolysis GO:0006508 175 0.043
response to oxidative stress GO:0006979 186 0.042
positive regulation of rna metabolic process GO:0051254 203 0.041
muscle cell proliferation GO:0033002 84 0.041
locomotion GO:0040011 237 0.041
programmed cell death GO:0012501 392 0.041
cation homeostasis GO:0055080 195 0.041
ribonucleoside triphosphate metabolic process GO:0009199 141 0.041
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.039
catabolic process GO:0009056 351 0.038
cell projection organization GO:0030030 302 0.038
reproductive structure development GO:0048608 128 0.038
central nervous system development GO:0007417 311 0.037
response to glucocorticoid GO:0051384 223 0.037
regulation of apoptotic process GO:0042981 335 0.037
purine nucleoside triphosphate metabolic process GO:0009144 141 0.037
metal ion transport GO:0030001 289 0.036
protein complex assembly GO:0006461 263 0.036
secretion by cell GO:0032940 248 0.035
single organism behavior GO:0044708 130 0.035
blood circulation GO:0008015 183 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
cellular component biogenesis GO:0044085 368 0.034
heart contraction GO:0060047 57 0.034
regulation of molecular function GO:0065009 398 0.034
aging GO:0007568 241 0.033
detection of stimulus GO:0051606 24 0.033
secretion GO:0046903 307 0.033
growth GO:0040007 165 0.032
single organism organelle organization GO:1902589 180 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
developmental process involved in reproduction GO:0003006 159 0.031
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.031
localization of cell GO:0051674 202 0.030
organ regeneration GO:0031100 101 0.029
sex differentiation GO:0007548 113 0.029
cellular ketone metabolic process GO:0042180 51 0.029
muscle cell differentiation GO:0042692 52 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
heart morphogenesis GO:0003007 3 0.029
apoptotic process GO:0006915 381 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.028
cell projection morphogenesis GO:0048858 123 0.028
positive regulation of programmed cell death GO:0043068 157 0.028
positive regulation of molecular function GO:0044093 230 0.028
multi organism reproductive process GO:0044703 262 0.028
chemical homeostasis GO:0048878 292 0.028
protein complex subunit organization GO:0071822 302 0.027
urogenital system development GO:0001655 78 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
regulation of system process GO:0044057 208 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.027
regulation of potassium ion transport GO:0043266 29 0.027
gland development GO:0048732 155 0.027
intracellular transport GO:0046907 185 0.027
response to decreased oxygen levels GO:0036293 237 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
cellular response to alcohol GO:0097306 87 0.027
multicellular organismal signaling GO:0035637 44 0.026
head development GO:0060322 247 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
response to peptide hormone GO:0043434 278 0.026
tissue development GO:0009888 252 0.026
heterocycle catabolic process GO:0046700 167 0.026
aromatic compound catabolic process GO:0019439 168 0.025
response to inorganic substance GO:0010035 377 0.025
naphthalene containing compound metabolic process GO:0090420 2 0.025
purine nucleoside triphosphate catabolic process GO:0009146 122 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
response to acid chemical GO:0001101 222 0.025
positive regulation of transport GO:0051050 245 0.024
skeletal muscle contraction GO:0003009 17 0.024
response to reactive oxygen species GO:0000302 120 0.024
endoplasmic reticulum to cytosol transport GO:1903513 4 0.024
nucleotide catabolic process GO:0009166 139 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
regulation of signal transduction GO:0009966 318 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
cellular component morphogenesis GO:0032989 155 0.023
inflammatory response GO:0006954 150 0.023
maintenance of location GO:0051235 17 0.023
regulation of secretion GO:0051046 224 0.023
cell part morphogenesis GO:0032990 123 0.022
regulation of hydrolase activity GO:0051336 143 0.022
regulation of cell development GO:0060284 263 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
behavior GO:0007610 205 0.022
cellular hormone metabolic process GO:0034754 49 0.022
calcium ion transport GO:0006816 131 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
circulatory system development GO:0072359 134 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
regeneration GO:0031099 163 0.021
cell cell signaling GO:0007267 335 0.021
response to nutrient levels GO:0031667 370 0.021
neuron development GO:0048666 286 0.021
positive regulation of gene expression GO:0010628 244 0.021
cell migration GO:0016477 197 0.021
cardiovascular system development GO:0072358 134 0.021
response to peptide GO:1901652 292 0.021
response to metal ion GO:0010038 253 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.020
oxidation reduction process GO:0055114 304 0.020
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.020
regulation of cell proliferation GO:0042127 359 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
regulation of calcium ion transport GO:0051924 77 0.020
rna metabolic process GO:0016070 406 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
macromolecular complex assembly GO:0065003 273 0.020
regulation of establishment of planar polarity GO:0090175 2 0.020
reproductive process GO:0022414 372 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
transcription dna templated GO:0006351 377 0.019
organic acid metabolic process GO:0006082 292 0.019
cell growth GO:0016049 104 0.019
regulation of membrane potential GO:0042391 110 0.019
neuron differentiation GO:0030182 368 0.019
nucleoside metabolic process GO:0009116 179 0.019
membrane repolarization GO:0086009 1 0.019
positive regulation of signal transduction GO:0009967 175 0.019
cytoskeleton organization GO:0007010 111 0.019
cardiac conduction GO:0061337 2 0.019
regulation of transporter activity GO:0032409 50 0.018
ras protein signal transduction GO:0007265 29 0.018
negative regulation of cell cycle phase transition GO:1901988 4 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
transmembrane transport GO:0055085 412 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of cell differentiation GO:0045595 320 0.018
single organism biosynthetic process GO:0044711 342 0.017
oxoacid metabolic process GO:0043436 290 0.017
positive regulation of developmental process GO:0051094 283 0.017
multicellular organism reproduction GO:0032504 233 0.017
ion transmembrane transport GO:0034220 365 0.017
circulatory system process GO:0003013 183 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
regulation of cell projection organization GO:0031344 175 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.017
neurological system process GO:0050877 219 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
membrane organization GO:0061024 94 0.017
multicellular organismal reproductive process GO:0048609 233 0.016
regulation of cell motility GO:2000145 131 0.016
positive regulation of cell death GO:0010942 184 0.016
protein localization to organelle GO:0033365 57 0.016
response to alkaloid GO:0043279 132 0.016
regulation of nervous system development GO:0051960 264 0.016
negative regulation of growth GO:0045926 37 0.016
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.016
cellular response to stress GO:0033554 269 0.016
single organism catabolic process GO:0044712 283 0.016
intracellular protein transport GO:0006886 79 0.016
muscle tissue development GO:0060537 58 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
response to activity GO:0014823 73 0.016
neuron projection development GO:0031175 273 0.016
protein modification by small protein conjugation or removal GO:0070647 35 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
development of primary sexual characteristics GO:0045137 107 0.015
protein oligomerization GO:0051259 191 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
response to corticosteroid GO:0031960 235 0.015
divalent metal ion transport GO:0070838 132 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
calcium ion transport into cytosol GO:0060402 38 0.015
cellular amine metabolic process GO:0044106 38 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
gonad development GO:0008406 104 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
protein homooligomerization GO:0051260 91 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
response to temperature stimulus GO:0009266 94 0.015
hepaticobiliary system development GO:0061008 90 0.015
cytosolic calcium ion transport GO:0060401 39 0.015
wound healing GO:0042060 122 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.014
organophosphate catabolic process GO:0046434 148 0.014
sequestering of calcium ion GO:0051208 8 0.014
potassium ion transport GO:0006813 97 0.014
heart process GO:0003015 57 0.014
heart development GO:0007507 72 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
nucleoside catabolic process GO:0009164 126 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
neuronal action potential GO:0019228 35 0.014
response to extracellular stimulus GO:0009991 380 0.014
synaptic transmission GO:0007268 235 0.014
chromosome segregation GO:0007059 2 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
cytoplasmic transport GO:0016482 115 0.014
alternative mrna splicing via spliceosome GO:0000380 4 0.014
protein transport GO:0015031 132 0.014
regulation of locomotion GO:0040012 148 0.013
intracellular signal transduction GO:0035556 314 0.013
action potential GO:0001508 54 0.013
calcium ion transmembrane transport GO:0070588 70 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of response to stress GO:0080134 126 0.013
response to insulin GO:0032868 133 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
protein targeting GO:0006605 61 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
rho protein signal transduction GO:0007266 11 0.013
erythrocyte differentiation GO:0030218 1 0.013
sexual reproduction GO:0019953 148 0.013
actin filament based movement GO:0030048 16 0.013
negative regulation of metabolic process GO:0009892 331 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of neuron projection development GO:0010975 161 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
reproduction GO:0000003 245 0.012
response to toxic substance GO:0009636 133 0.012
nucleic acid templated transcription GO:0097659 379 0.012
striated muscle cell development GO:0055002 26 0.012
actin filament based process GO:0030029 86 0.012
cellular macromolecule catabolic process GO:0044265 29 0.012
response to ethanol GO:0045471 162 0.012
regulation of neurogenesis GO:0050767 247 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
renal system development GO:0072001 67 0.012
positive regulation of cell communication GO:0010647 271 0.012
sensory perception of bitter taste GO:0050913 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
response to ionizing radiation GO:0010212 59 0.012
response to testosterone GO:0033574 55 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
anion transport GO:0006820 178 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
carbohydrate metabolic process GO:0005975 130 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
chemosensory behavior GO:0007635 2 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
isoprenoid metabolic process GO:0006720 45 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
developmental growth GO:0048589 100 0.011
response to cytokine GO:0034097 215 0.011
response to glucose GO:0009749 136 0.011
gamete generation GO:0007276 124 0.011
hexose metabolic process GO:0019318 58 0.011
regulation of organelle organization GO:0033043 80 0.011
response to hexose GO:0009746 144 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular response to lipid GO:0071396 201 0.011
regulation of heart contraction GO:0008016 48 0.011
response to growth factor GO:0070848 189 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of secretion by cell GO:1903530 208 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
regulation of cell growth GO:0001558 85 0.011
cell motility GO:0048870 202 0.011
protein tetramerization GO:0051262 38 0.011
liver development GO:0001889 90 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
establishment of tissue polarity GO:0007164 2 0.011
lipid storage GO:0019915 1 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.011
negative regulation of transport GO:0051051 136 0.011
response to estradiol GO:0032355 164 0.011
male gonad development GO:0008584 59 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
kidney development GO:0001822 67 0.010
cardiac chamber development GO:0003205 1 0.010
dna metabolic process GO:0006259 96 0.010
tissue remodeling GO:0048771 40 0.010
regulation of catalytic activity GO:0050790 304 0.010
response to biotic stimulus GO:0009607 226 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
regulation of synaptic transmission GO:0050804 141 0.010
rhythmic process GO:0048511 156 0.010
positive regulation of signaling GO:0023056 270 0.010
nitrogen compound transport GO:0071705 229 0.010
negative regulation of cardiac muscle tissue development GO:0055026 3 0.010
response to monosaccharide GO:0034284 159 0.010
erythrocyte homeostasis GO:0034101 2 0.010
response to insecticide GO:0017085 21 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
amine metabolic process GO:0009308 38 0.010
regulation of rna metabolic process GO:0051252 391 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
cation transport GO:0006812 382 0.010

Hrc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cardiovascular system disease DOID:1287 0 0.024
muscular disease DOID:0080000 0 0.023
musculoskeletal system disease DOID:17 0 0.023
muscle tissue disease DOID:66 0 0.023
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
myopathy DOID:423 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013