Rattus norvegicus

0 known processes

Rgl2

ral guanine nucleotide dissociation stimulator-like 2

(Aliases: MGC124925,Ke1.5,Rab2l)

Rgl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.205
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.148
negative regulation of cellular metabolic process GO:0031324 281 0.141
transcription dna templated GO:0006351 377 0.129
intracellular signal transduction GO:0035556 314 0.104
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.099
positive regulation of cellular biosynthetic process GO:0031328 295 0.095
regulation of nucleic acid templated transcription GO:1903506 380 0.091
regulation of rna biosynthetic process GO:2001141 381 0.090
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.090
nucleic acid templated transcription GO:0097659 379 0.086
negative regulation of macromolecule metabolic process GO:0010605 260 0.079
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.072
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.069
regulation of rna metabolic process GO:0051252 391 0.069
positive regulation of biosynthetic process GO:0009891 319 0.069
negative regulation of cellular biosynthetic process GO:0031327 161 0.068
negative regulation of nucleic acid templated transcription GO:1903507 117 0.067
nucleotide metabolic process GO:0009117 279 0.066
negative regulation of rna biosynthetic process GO:1902679 118 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
protein complex assembly GO:0006461 263 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.060
regulation of signal transduction GO:0009966 318 0.058
negative regulation of metabolic process GO:0009892 331 0.055
positive regulation of transcription dna templated GO:0045893 197 0.054
positive regulation of gene expression GO:0010628 244 0.053
response to extracellular stimulus GO:0009991 380 0.051
programmed cell death GO:0012501 392 0.051
regulation of cellular component organization GO:0051128 368 0.051
protein complex subunit organization GO:0071822 302 0.048
rna biosynthetic process GO:0032774 380 0.048
positive regulation of rna metabolic process GO:0051254 203 0.048
regulation of molecular function GO:0065009 398 0.048
brain development GO:0007420 247 0.047
negative regulation of biosynthetic process GO:0009890 168 0.046
regulation of multicellular organismal development GO:2000026 376 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
response to cytokine GO:0034097 215 0.043
cellular response to stress GO:0033554 269 0.043
regulation of catalytic activity GO:0050790 304 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.042
small gtpase mediated signal transduction GO:0007264 36 0.042
negative regulation of transcription dna templated GO:0045892 116 0.042
positive regulation of cellular component organization GO:0051130 200 0.042
positive regulation of rna biosynthetic process GO:1902680 197 0.041
protein phosphorylation GO:0006468 345 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
catabolic process GO:0009056 351 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
central nervous system development GO:0007417 311 0.039
reproductive process GO:0022414 372 0.038
locomotion GO:0040011 237 0.038
protein complex biogenesis GO:0070271 263 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of protein metabolic process GO:0051246 289 0.037
regulation of phosphate metabolic process GO:0019220 349 0.036
neurological system process GO:0050877 219 0.036
positive regulation of nucleic acid templated transcription GO:1903508 197 0.036
apoptotic process GO:0006915 381 0.036
regulation of transcription dna templated GO:0006355 374 0.036
neuron differentiation GO:0030182 368 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
bmp signaling pathway GO:0030509 4 0.035
regulation of canonical wnt signaling pathway GO:0060828 4 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
cellular ketone metabolic process GO:0042180 51 0.034
macromolecular complex subunit organization GO:0043933 339 0.034
regulation of cell cycle GO:0051726 73 0.033
cell projection organization GO:0030030 302 0.032
negative regulation of gene expression GO:0010629 199 0.032
organelle organization GO:0006996 266 0.032
organic acid metabolic process GO:0006082 292 0.032
regulation of neurogenesis GO:0050767 247 0.030
cellular response to cytokine stimulus GO:0071345 127 0.030
regulation of nervous system development GO:0051960 264 0.030
cellular component movement GO:0006928 248 0.029
positive regulation of apoptotic process GO:0043065 154 0.029
cell cell signaling GO:0007267 335 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
regulation of cell development GO:0060284 263 0.029
neuron projection development GO:0031175 273 0.028
response to external biotic stimulus GO:0043207 221 0.027
cell cycle checkpoint GO:0000075 2 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
mechanoreceptor differentiation GO:0042490 2 0.027
organophosphate metabolic process GO:0019637 370 0.026
multicellular organism reproduction GO:0032504 233 0.026
tissue development GO:0009888 252 0.026
heart morphogenesis GO:0003007 3 0.025
purine containing compound metabolic process GO:0072521 253 0.025
behavior GO:0007610 205 0.025
regulation of neuron differentiation GO:0045664 208 0.024
single organism reproductive process GO:0044702 297 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
homeostatic process GO:0042592 331 0.024
regulation of intracellular signal transduction GO:1902531 218 0.023
regulation of cellular component movement GO:0051270 150 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
oxoacid metabolic process GO:0043436 290 0.023
regulation of cell differentiation GO:0045595 320 0.023
multi organism reproductive process GO:0044703 262 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
regulation of apoptotic process GO:0042981 335 0.023
response to nutrient levels GO:0031667 370 0.023
response to carbohydrate GO:0009743 183 0.022
hair cell differentiation GO:0035315 2 0.022
positive regulation of signaling GO:0023056 270 0.022
ras protein signal transduction GO:0007265 29 0.021
organic substance catabolic process GO:1901575 316 0.021
positive regulation of hydrolase activity GO:0051345 86 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
cellular component assembly GO:0022607 360 0.021
negative regulation of cell communication GO:0010648 158 0.021
response to wounding GO:0009611 254 0.021
secretion by cell GO:0032940 248 0.021
proteolysis GO:0006508 175 0.021
cytoskeleton organization GO:0007010 111 0.021
sensory perception GO:0007600 101 0.021
cellular amine metabolic process GO:0044106 38 0.020
cell cycle GO:0007049 101 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
growth GO:0040007 165 0.020
positive regulation of cell death GO:0010942 184 0.019
regulation of cell cycle g1 s phase transition GO:1902806 7 0.019
nucleoside catabolic process GO:0009164 126 0.019
inner ear receptor cell differentiation GO:0060113 2 0.019
cellular homeostasis GO:0019725 252 0.019
response to mechanical stimulus GO:0009612 134 0.019
vasculogenesis GO:0001570 3 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
macromolecular complex assembly GO:0065003 273 0.019
response to other organism GO:0051707 220 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
regulation of phosphorylation GO:0042325 248 0.018
dna metabolic process GO:0006259 96 0.018
vesicle mediated transport GO:0016192 181 0.018
amine metabolic process GO:0009308 38 0.018
head development GO:0060322 247 0.018
negative regulation of signaling GO:0023057 157 0.018
regulation of programmed cell death GO:0043067 341 0.018
regulation of cell migration GO:0030334 128 0.018
response to metal ion GO:0010038 253 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of fat cell differentiation GO:0045598 3 0.017
reproductive system development GO:0061458 128 0.017
erythrocyte differentiation GO:0030218 1 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
dna integrity checkpoint GO:0031570 2 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
negative regulation of cell cycle phase transition GO:1901988 4 0.017
regulation of locomotion GO:0040012 148 0.016
nucleoside metabolic process GO:0009116 179 0.016
single organism behavior GO:0044708 130 0.016
regulation of catabolic process GO:0009894 113 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
response to biotic stimulus GO:0009607 226 0.016
regulation of growth GO:0040008 105 0.016
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
reproduction GO:0000003 245 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
aging GO:0007568 241 0.016
cell cycle process GO:0022402 57 0.016
response to peptide GO:1901652 292 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
tube development GO:0035295 89 0.015
peptidyl amino acid modification GO:0018193 126 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
tissue regeneration GO:0042246 36 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
positive regulation of cell communication GO:0010647 271 0.015
cellular component biogenesis GO:0044085 368 0.015
positive regulation of cell development GO:0010720 176 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
actin filament organization GO:0007015 42 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
negative regulation of signal transduction GO:0009968 83 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.014
reproductive structure development GO:0048608 128 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
embryonic pattern specification GO:0009880 1 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cell morphogenesis GO:0000902 142 0.014
cellular ion homeostasis GO:0006873 184 0.014
response to temperature stimulus GO:0009266 94 0.014
positive regulation of nervous system development GO:0051962 178 0.014
negative regulation of osteoblast differentiation GO:0045668 2 0.014
mammary gland epithelium development GO:0061180 1 0.014
regulation of cell projection organization GO:0031344 175 0.014
single organism biosynthetic process GO:0044711 342 0.013
response to muramyl dipeptide GO:0032495 1 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
cell cycle g1 s phase transition GO:0044843 13 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
response to glucose GO:0009749 136 0.013
multicellular organism growth GO:0035264 1 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
endocytosis GO:0006897 84 0.013
regulation of response to external stimulus GO:0032101 106 0.013
regulation of embryonic development GO:0045995 2 0.013
mitotic cell cycle GO:0000278 49 0.013
positive regulation of developmental process GO:0051094 283 0.013
circulatory system development GO:0072359 134 0.013
positive regulation of signal transduction GO:0009967 175 0.013
response to tumor necrosis factor GO:0034612 56 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
tube formation GO:0035148 3 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
spindle organization GO:0007051 2 0.012
chemical homeostasis GO:0048878 292 0.012
cell migration GO:0016477 197 0.012
response to radiation GO:0009314 137 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
anterior posterior pattern specification GO:0009952 1 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
regulation of neuron projection development GO:0010975 161 0.012
negative regulation of molecular function GO:0044092 133 0.012
mitotic cell cycle process GO:1903047 35 0.012
response to oxygen levels GO:0070482 265 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
aromatic compound catabolic process GO:0019439 168 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
negative regulation of cell death GO:0060548 229 0.012
nucleotide catabolic process GO:0009166 139 0.012
gastrulation GO:0007369 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
axis specification GO:0009798 4 0.012
rna localization GO:0006403 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
neuron development GO:0048666 286 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
p38mapk cascade GO:0038066 1 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regulation of mapk cascade GO:0043408 116 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
erythrocyte homeostasis GO:0034101 2 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to ionizing radiation GO:0010212 59 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
positive regulation of secretion GO:0051047 140 0.011
secretion GO:0046903 307 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
ion homeostasis GO:0050801 212 0.011
response to acid chemical GO:0001101 222 0.011
sensory organ development GO:0007423 74 0.011
response to bacterium GO:0009617 200 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
cellular protein complex assembly GO:0043623 44 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
circadian rhythm GO:0007623 88 0.011
positive regulation of growth GO:0045927 55 0.011
inflammatory response GO:0006954 150 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
localization of cell GO:0051674 202 0.011
positive regulation of transport GO:0051050 245 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of organelle organization GO:0033043 80 0.011
rhythmic process GO:0048511 156 0.011
gamete generation GO:0007276 124 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
chromosome organization GO:0051276 36 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
cell motility GO:0048870 202 0.010
regulation of cell proliferation GO:0042127 359 0.010
response to ethanol GO:0045471 162 0.010
defense response to gram positive bacterium GO:0050830 2 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
regulation of immune response GO:0050776 55 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
regulation of cell cycle process GO:0010564 31 0.010
small molecule biosynthetic process GO:0044283 124 0.010
response to nutrient GO:0007584 248 0.010
regulation of skeletal muscle tissue growth GO:0048631 3 0.010
protein heterooligomerization GO:0051291 89 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
protein oligomerization GO:0051259 191 0.010
response to inorganic substance GO:0010035 377 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
regulation of proteolysis GO:0030162 66 0.010

Rgl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.015
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010