Rattus norvegicus

63 known processes

Aspa

aspartoacylase

(Aliases: MGC93407,MGC93408)

Aspa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.102
single organism biosynthetic process GO:0044711 342 0.098
organic acid metabolic process GO:0006082 292 0.091
carboxylic acid metabolic process GO:0019752 289 0.080
response to biotic stimulus GO:0009607 226 0.075
positive regulation of transport GO:0051050 245 0.074
regulation of cell proliferation GO:0042127 359 0.065
lipid metabolic process GO:0006629 283 0.065
response to inorganic substance GO:0010035 377 0.065
cellular ion homeostasis GO:0006873 184 0.064
cell cell signaling GO:0007267 335 0.063
g protein coupled receptor signaling pathway GO:0007186 242 0.062
response to other organism GO:0051707 220 0.061
apoptotic process GO:0006915 381 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.060
regulation of immune system process GO:0002682 123 0.060
response to nutrient GO:0007584 248 0.060
organophosphate metabolic process GO:0019637 370 0.057
regulation of cellular localization GO:0060341 263 0.057
nitrogen compound transport GO:0071705 229 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.054
cellular lipid metabolic process GO:0044255 208 0.053
aging GO:0007568 241 0.053
tissue development GO:0009888 252 0.052
positive regulation of signaling GO:0023056 270 0.051
positive regulation of cell proliferation GO:0008284 249 0.051
intracellular signal transduction GO:0035556 314 0.050
regulation of programmed cell death GO:0043067 341 0.049
cation transport GO:0006812 382 0.048
organic substance catabolic process GO:1901575 316 0.048
cellular amino acid metabolic process GO:0006520 107 0.047
cellular ketone metabolic process GO:0042180 51 0.045
cellular chemical homeostasis GO:0055082 247 0.044
carbohydrate metabolic process GO:0005975 130 0.043
mapk cascade GO:0000165 140 0.043
regulation of cellular ketone metabolic process GO:0010565 27 0.043
response to external biotic stimulus GO:0043207 221 0.042
response to extracellular stimulus GO:0009991 380 0.042
response to metal ion GO:0010038 253 0.041
cation homeostasis GO:0055080 195 0.041
catabolic process GO:0009056 351 0.041
macromolecule localization GO:0033036 252 0.040
response to nutrient levels GO:0031667 370 0.040
ion homeostasis GO:0050801 212 0.039
transmembrane transport GO:0055085 412 0.039
regulation of phosphate metabolic process GO:0019220 349 0.038
secretion GO:0046903 307 0.038
cellular cation homeostasis GO:0030003 180 0.038
regulation of protein modification process GO:0031399 194 0.037
blood circulation GO:0008015 183 0.037
small molecule catabolic process GO:0044282 59 0.037
positive regulation of cell death GO:0010942 184 0.036
cellular response to endogenous stimulus GO:0071495 377 0.036
regulation of anatomical structure size GO:0090066 135 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
regulation of anatomical structure morphogenesis GO:0022603 141 0.035
divalent inorganic cation transport GO:0072511 134 0.035
response to glucocorticoid GO:0051384 223 0.035
regulation of apoptotic process GO:0042981 335 0.035
cellular response to stress GO:0033554 269 0.034
protein phosphorylation GO:0006468 345 0.034
response to oxidative stress GO:0006979 186 0.034
regulation of homeostatic process GO:0032844 101 0.034
lipid biosynthetic process GO:0008610 128 0.034
single organism catabolic process GO:0044712 283 0.033
monocarboxylic acid metabolic process GO:0032787 152 0.033
cellular amine metabolic process GO:0044106 38 0.033
central nervous system development GO:0007417 311 0.033
homeostatic process GO:0042592 331 0.033
cellular response to lipid GO:0071396 201 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.031
positive regulation of cell communication GO:0010647 271 0.031
protein complex assembly GO:0006461 263 0.031
regulation of hormone levels GO:0010817 187 0.031
cellular metal ion homeostasis GO:0006875 172 0.031
regulation of peptide transport GO:0090087 87 0.030
cellular nitrogen compound catabolic process GO:0044270 163 0.030
response to ketone GO:1901654 182 0.030
fatty acid metabolic process GO:0006631 99 0.030
cellular component biogenesis GO:0044085 368 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
macromolecular complex assembly GO:0065003 273 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
regulation of secretion by cell GO:1903530 208 0.029
secretion by cell GO:0032940 248 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
positive regulation of secretion by cell GO:1903532 128 0.029
regulation of system process GO:0044057 208 0.029
programmed cell death GO:0012501 392 0.028
response to wounding GO:0009611 254 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
cellular component movement GO:0006928 248 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
cell morphogenesis GO:0000902 142 0.028
synaptic transmission GO:0007268 235 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
positive regulation of intracellular signal transduction GO:1902533 138 0.028
response to lipopolysaccharide GO:0032496 191 0.027
aromatic compound catabolic process GO:0019439 168 0.027
regulation of hormone secretion GO:0046883 106 0.027
response to hypoxia GO:0001666 231 0.027
circulatory system process GO:0003013 183 0.027
anion transport GO:0006820 178 0.027
regulation of ion transport GO:0043269 245 0.026
cellular homeostasis GO:0019725 252 0.026
regulation of signal transduction GO:0009966 318 0.026
negative regulation of transport GO:0051051 136 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
ion transmembrane transport GO:0034220 365 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
regulation of cell growth GO:0001558 85 0.025
inorganic cation transmembrane transport GO:0098662 202 0.025
hormone transport GO:0009914 121 0.025
regulation of molecular function GO:0065009 398 0.025
regulation of metal ion transport GO:0010959 118 0.025
regulation of phosphorylation GO:0042325 248 0.025
metal ion transport GO:0030001 289 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
negative regulation of signaling GO:0023057 157 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
regulation of secretion GO:0051046 224 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
cation transmembrane transport GO:0098655 263 0.024
protein complex subunit organization GO:0071822 302 0.024
protein complex biogenesis GO:0070271 263 0.024
cellular component assembly GO:0022607 360 0.024
response to bacterium GO:0009617 200 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
protein oligomerization GO:0051259 191 0.024
positive regulation of developmental process GO:0051094 283 0.023
amine metabolic process GO:0009308 38 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cellular response to fluid shear stress GO:0071498 4 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
protein localization GO:0008104 191 0.023
positive regulation of immune system process GO:0002684 90 0.023
calcium ion homeostasis GO:0055074 162 0.023
cellular catabolic process GO:0044248 295 0.023
localization of cell GO:0051674 202 0.023
establishment of protein localization GO:0045184 141 0.023
nucleotide metabolic process GO:0009117 279 0.023
chemical homeostasis GO:0048878 292 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
negative regulation of metabolic process GO:0009892 331 0.022
heterocycle catabolic process GO:0046700 167 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
defense response GO:0006952 194 0.022
cellular response to peptide GO:1901653 133 0.022
response to peptide hormone GO:0043434 278 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
oxidation reduction process GO:0055114 304 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
regulation of body fluid levels GO:0050878 90 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
metal ion homeostasis GO:0055065 186 0.020
regulation of proteasomal protein catabolic process GO:0061136 4 0.020
neurological system process GO:0050877 219 0.020
response to peptide GO:1901652 292 0.020
growth GO:0040007 165 0.020
response to oxygen levels GO:0070482 265 0.020
regulation of mapk cascade GO:0043408 116 0.020
divalent metal ion transport GO:0070838 132 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
organic acid transport GO:0015849 116 0.019
neuron development GO:0048666 286 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
wound healing GO:0042060 122 0.019
response to acid chemical GO:0001101 222 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
intracellular transport GO:0046907 185 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
organophosphate catabolic process GO:0046434 148 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
regulation of peptide secretion GO:0002791 82 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
biological adhesion GO:0022610 110 0.018
regulation of cellular component organization GO:0051128 368 0.018
endocytosis GO:0006897 84 0.018
regulation of kinase activity GO:0043549 117 0.018
regulation of transferase activity GO:0051338 123 0.018
organelle organization GO:0006996 266 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
small molecule biosynthetic process GO:0044283 124 0.018
positive regulation of signal transduction GO:0009967 175 0.018
positive regulation of secretion GO:0051047 140 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
calcium ion transport GO:0006816 131 0.018
ras protein signal transduction GO:0007265 29 0.018
negative regulation of cell communication GO:0010648 158 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
hormone secretion GO:0046879 115 0.018
regulation of membrane potential GO:0042391 110 0.017
organ morphogenesis GO:0009887 75 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
amide transport GO:0042886 105 0.017
response to growth factor GO:0070848 189 0.017
immune system process GO:0002376 204 0.017
signal release GO:0023061 145 0.017
positive regulation of catabolic process GO:0009896 78 0.017
gastrulation GO:0007369 2 0.017
purine containing compound metabolic process GO:0072521 253 0.017
response to insulin GO:0032868 133 0.017
response to decreased oxygen levels GO:0036293 237 0.017
response to corticosteroid GO:0031960 235 0.017
negative regulation of cell death GO:0060548 229 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
vesicle mediated transport GO:0016192 181 0.017
regulation of protein metabolic process GO:0051246 289 0.017
positive regulation of protein metabolic process GO:0051247 178 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
regulation of cell differentiation GO:0045595 320 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
carboxylic acid transport GO:0046942 115 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
nucleoside metabolic process GO:0009116 179 0.016
heart morphogenesis GO:0003007 3 0.016
multicellular organismal homeostasis GO:0048871 49 0.016
organic anion transport GO:0015711 132 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
proteolysis GO:0006508 175 0.016
cell migration GO:0016477 197 0.016
response to estrogen GO:0043627 232 0.016
gliogenesis GO:0042063 93 0.016
response to ethanol GO:0045471 162 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
kidney development GO:0001822 67 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
cell motility GO:0048870 202 0.016
cellular response to organonitrogen compound GO:0071417 197 0.015
regulation of calcium ion transport GO:0051924 77 0.015
regulation of ion homeostasis GO:2000021 63 0.015
positive regulation of homeostatic process GO:0032846 49 0.015
cellular lipid catabolic process GO:0044242 37 0.015
protein transport GO:0015031 132 0.015
eye morphogenesis GO:0048592 4 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
peptide secretion GO:0002790 86 0.015
transmission of nerve impulse GO:0019226 42 0.015
purine containing compound catabolic process GO:0072523 138 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
cell activation GO:0001775 97 0.015
regulation of tube size GO:0035150 89 0.015
cell adhesion GO:0007155 110 0.015
reproductive process GO:0022414 372 0.015
regulation of growth GO:0040008 105 0.015
mesoderm development GO:0007498 2 0.015
positive regulation of transferase activity GO:0051347 81 0.015
response to zinc ion GO:0010043 39 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
multicellular organism reproduction GO:0032504 233 0.014
carboxylic acid catabolic process GO:0046395 49 0.014
head development GO:0060322 247 0.014
action potential GO:0001508 54 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of protein modification process GO:0031401 142 0.014
muscle cell proliferation GO:0033002 84 0.014
peptide transport GO:0015833 97 0.014
regulation of protein localization GO:0032880 81 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
response to temperature stimulus GO:0009266 94 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of blood circulation GO:1903522 110 0.014
regulation of response to stress GO:0080134 126 0.014
multicellular organism growth GO:0035264 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
regulation of blood pressure GO:0008217 83 0.014
regulation of nervous system development GO:0051960 264 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
neuron differentiation GO:0030182 368 0.014
reproduction GO:0000003 245 0.014
nucleoside catabolic process GO:0009164 126 0.014
regulation of catalytic activity GO:0050790 304 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
cellular component morphogenesis GO:0032989 155 0.014
multi organism reproductive process GO:0044703 262 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
vascular process in circulatory system GO:0003018 96 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
organic acid catabolic process GO:0016054 49 0.013
immune response GO:0006955 104 0.013
cell growth GO:0016049 104 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
fatty acid catabolic process GO:0009062 26 0.013
nucleotide catabolic process GO:0009166 139 0.013
transcription dna templated GO:0006351 377 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
response to vitamin GO:0033273 131 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
single organism reproductive process GO:0044702 297 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
rho protein signal transduction GO:0007266 11 0.013
tissue remodeling GO:0048771 40 0.013
regulation of protein phosphorylation GO:0001932 183 0.012
single organism intracellular transport GO:1902582 166 0.012
cytoplasmic transport GO:0016482 115 0.012
rna biosynthetic process GO:0032774 380 0.012
dna metabolic process GO:0006259 96 0.012
renal system development GO:0072001 67 0.012
inflammatory response GO:0006954 150 0.012
sodium ion transport GO:0006814 82 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
cellular response to alcohol GO:0097306 87 0.012
muscle system process GO:0003012 115 0.012
epithelium development GO:0060429 96 0.012
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of neurogenesis GO:0050767 247 0.012
sequestering of calcium ion GO:0051208 8 0.012
neuron projection development GO:0031175 273 0.012
monoamine transport GO:0015844 43 0.012
organic acid biosynthetic process GO:0016053 83 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
phospholipid metabolic process GO:0006644 61 0.012
single organism membrane organization GO:0044802 74 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
sensory perception of pain GO:0019233 73 0.012
behavior GO:0007610 205 0.012
positive regulation of molecular function GO:0044093 230 0.012
rna metabolic process GO:0016070 406 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
reactive oxygen species metabolic process GO:0072593 37 0.011
locomotion GO:0040011 237 0.011
regulation of insulin secretion GO:0050796 65 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
lipid catabolic process GO:0016042 46 0.011
cognition GO:0050890 92 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
positive regulation of gene expression GO:0010628 244 0.011
positive regulation of ion transport GO:0043270 94 0.011
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
response to activity GO:0014823 73 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
regulation of response to wounding GO:1903034 69 0.011
peptide hormone secretion GO:0030072 84 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
cellular protein localization GO:0034613 122 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of catabolic process GO:0009894 113 0.011
cell projection organization GO:0030030 302 0.011
lipid transport GO:0006869 61 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of protein kinase activity GO:0045859 105 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
urogenital system development GO:0001655 78 0.011
cellular response to oxygen levels GO:0071453 60 0.011
axon development GO:0061564 96 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
response to alkaloid GO:0043279 132 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
gamete generation GO:0007276 124 0.011
response to testosterone GO:0033574 55 0.011
brain development GO:0007420 247 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
positive regulation of cell motility GO:2000147 97 0.010
sensory perception GO:0007600 101 0.010
response to mechanical stimulus GO:0009612 134 0.010
neuron neuron synaptic transmission GO:0007270 60 0.010
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.010
glycerolipid metabolic process GO:0046486 67 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
sulfur amino acid metabolic process GO:0000096 9 0.010
adult locomotory behavior GO:0008344 4 0.010
positive regulation of kinase activity GO:0033674 77 0.010
developmental growth GO:0048589 100 0.010
cellular macromolecule localization GO:0070727 122 0.010
chromosome segregation GO:0007059 2 0.010
amino acid transport GO:0006865 70 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.010

Aspa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
Human
nervous system disease DOID:863 0 0.035
Human
sensory system disease DOID:0050155 0 0.018
central nervous system disease DOID:331 0 0.017
Human
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.012