Rattus norvegicus

133 known processes

Eng

endoglin

(Aliases: MGC124909)

Eng biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of isotype switching GO:0045830 1 0.208
intracellular signal transduction GO:0035556 314 0.115
urogenital system development GO:0001655 78 0.104
programmed cell death GO:0012501 392 0.104
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.103
apoptotic process GO:0006915 381 0.099
cellular response to hormone stimulus GO:0032870 247 0.086
cellular amino acid metabolic process GO:0006520 107 0.082
regulation of apoptotic process GO:0042981 335 0.079
regulation of cellular amine metabolic process GO:0033238 8 0.078
positive regulation of biosynthetic process GO:0009891 319 0.075
negative regulation of programmed cell death GO:0043069 183 0.066
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.065
cellular response to endogenous stimulus GO:0071495 377 0.065
regulation of multicellular organismal development GO:2000026 376 0.063
cellular amine metabolic process GO:0044106 38 0.063
protein complex assembly GO:0006461 263 0.062
amine metabolic process GO:0009308 38 0.060
regulation of phosphate metabolic process GO:0019220 349 0.058
glycosyl compound metabolic process GO:1901657 182 0.058
immunoglobulin mediated immune response GO:0016064 4 0.055
response to extracellular stimulus GO:0009991 380 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
positive regulation of response to stimulus GO:0048584 285 0.050
single organism biosynthetic process GO:0044711 342 0.049
rhythmic process GO:0048511 156 0.049
rna biosynthetic process GO:0032774 380 0.049
regulation of signal transduction GO:0009966 318 0.049
b cell mediated immunity GO:0019724 4 0.049
cation homeostasis GO:0055080 195 0.048
positive regulation of gene expression GO:0010628 244 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
reproductive process GO:0022414 372 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
response to glucose GO:0009749 136 0.045
regulation of immunoglobulin production GO:0002637 4 0.044
cellular component assembly GO:0022607 360 0.044
positive regulation of nervous system development GO:0051962 178 0.044
regulation of programmed cell death GO:0043067 341 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
renal system development GO:0072001 67 0.041
response to monosaccharide GO:0034284 159 0.041
muscle structure development GO:0061061 87 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
negative regulation of metabolic process GO:0009892 331 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
peptidyl amino acid modification GO:0018193 126 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
positive regulation of cellular amine metabolic process GO:0033240 3 0.035
regulation of smooth muscle cell proliferation GO:0048660 75 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
organic acid metabolic process GO:0006082 292 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
inflammatory response GO:0006954 150 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
transcription dna templated GO:0006351 377 0.033
regulation of transcription dna templated GO:0006355 374 0.033
female pregnancy GO:0007565 122 0.033
positive regulation of developmental process GO:0051094 283 0.032
regulation of response to stress GO:0080134 126 0.032
positive regulation of signal transduction GO:0009967 175 0.031
cellular divalent inorganic cation homeostasis GO:0072503 162 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
regulation of rna metabolic process GO:0051252 391 0.031
regulation of system process GO:0044057 208 0.031
response to carbohydrate GO:0009743 183 0.031
response to estrogen GO:0043627 232 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
smooth muscle cell proliferation GO:0048659 77 0.030
cellular ketone metabolic process GO:0042180 51 0.030
protein oligomerization GO:0051259 191 0.030
cellular response to alcohol GO:0097306 87 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
reproductive system development GO:0061458 128 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
cellular response to nitrogen compound GO:1901699 210 0.030
cellular cation homeostasis GO:0030003 180 0.030
response to mechanical stimulus GO:0009612 134 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
cellular response to glucocorticoid stimulus GO:0071385 68 0.029
cellular response to insulin stimulus GO:0032869 81 0.028
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.028
oxoacid metabolic process GO:0043436 290 0.028
tissue remodeling GO:0048771 40 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
response to nutrient GO:0007584 248 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
purine nucleotide biosynthetic process GO:0006164 83 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
cellular response to cytokine stimulus GO:0071345 127 0.027
negative regulation of gene expression GO:0010629 199 0.026
pro t cell differentiation GO:0002572 1 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
response to oxygen levels GO:0070482 265 0.026
regulation of protein metabolic process GO:0051246 289 0.026
regulation of cell development GO:0060284 263 0.026
defense response GO:0006952 194 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
rna metabolic process GO:0016070 406 0.025
immune system process GO:0002376 204 0.025
regulation of neuron death GO:1901214 115 0.025
ovulation cycle GO:0042698 67 0.025
response to glucocorticoid GO:0051384 223 0.025
response to hexose GO:0009746 144 0.025
t helper 1 type immune response GO:0042088 1 0.025
vesicle mediated transport GO:0016192 181 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
response to growth factor GO:0070848 189 0.024
cellular response to corticosteroid stimulus GO:0071384 69 0.024
response to estradiol GO:0032355 164 0.024
metal ion homeostasis GO:0055065 186 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
negative regulation of nervous system development GO:0051961 79 0.024
response to activity GO:0014823 73 0.024
regulation of immune system process GO:0002682 123 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
muscle cell proliferation GO:0033002 84 0.023
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.023
circulatory system development GO:0072359 134 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
regulation of protein modification process GO:0031399 194 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
response to insulin GO:0032868 133 0.023
nucleoside metabolic process GO:0009116 179 0.022
response to decreased oxygen levels GO:0036293 237 0.022
response to ketone GO:1901654 182 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
negative regulation of cell death GO:0060548 229 0.022
regulation of catalytic activity GO:0050790 304 0.022
cellular homeostasis GO:0019725 252 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
regulation of tube size GO:0035150 89 0.022
striated muscle tissue development GO:0014706 58 0.022
nucleotide metabolic process GO:0009117 279 0.021
epithelial cell differentiation GO:0030855 71 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
response to metal ion GO:0010038 253 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
chemical homeostasis GO:0048878 292 0.021
embryonic pattern specification GO:0009880 1 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
response to corticosteroid GO:0031960 235 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
response to peptide GO:1901652 292 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of angiogenesis GO:0045766 28 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
response to wounding GO:0009611 254 0.020
single organism reproductive process GO:0044702 297 0.020
positive regulation of neuron death GO:1901216 43 0.020
macromolecular complex assembly GO:0065003 273 0.020
muscle organ development GO:0007517 50 0.020
organophosphate metabolic process GO:0019637 370 0.020
circulatory system process GO:0003013 183 0.020
cellular response to external stimulus GO:0071496 118 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
growth GO:0040007 165 0.019
regulation of cell proliferation GO:0042127 359 0.019
homeostatic process GO:0042592 331 0.019
tissue development GO:0009888 252 0.019
developmental growth GO:0048589 100 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
negative regulation of developmental process GO:0051093 125 0.019
regulation of transcription regulatory region dna binding GO:2000677 4 0.019
cellular catabolic process GO:0044248 295 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
response to inorganic substance GO:0010035 377 0.019
regeneration GO:0031099 163 0.019
t cell differentiation GO:0030217 9 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
positive regulation of cell projection organization GO:0031346 111 0.018
muscle tissue development GO:0060537 58 0.018
response to bacterium GO:0009617 200 0.018
reproduction GO:0000003 245 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
bmp signaling pathway GO:0030509 4 0.018
protein complex biogenesis GO:0070271 263 0.018
regulation of reactive oxygen species metabolic process GO:2000377 26 0.018
neurological system process GO:0050877 219 0.018
catabolic process GO:0009056 351 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
response to other organism GO:0051707 220 0.018
immune effector process GO:0002252 53 0.017
response to hypoxia GO:0001666 231 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
calcium ion homeostasis GO:0055074 162 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.017
common partner smad protein phosphorylation GO:0007182 1 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to vitamin GO:0033273 131 0.017
cellular ion homeostasis GO:0006873 184 0.017
regulation of molecular function GO:0065009 398 0.016
regulation of muscle system process GO:0090257 79 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
ion homeostasis GO:0050801 212 0.016
localization of cell GO:0051674 202 0.016
positive regulation of locomotion GO:0040017 102 0.016
hormone metabolic process GO:0042445 69 0.016
multi multicellular organism process GO:0044706 138 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
female gonad development GO:0008585 53 0.016
response to tumor necrosis factor GO:0034612 56 0.016
protein complex subunit organization GO:0071822 302 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
multicellular organismal macromolecule metabolic process GO:0044259 21 0.016
regulation of immunoglobulin mediated immune response GO:0002889 2 0.016
secretion GO:0046903 307 0.016
liver development GO:0001889 90 0.016
single organism catabolic process GO:0044712 283 0.016
response to ethanol GO:0045471 162 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
skeletal muscle tissue development GO:0007519 31 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
cellular component movement GO:0006928 248 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
positive regulation of response to wounding GO:1903036 34 0.015
regulation of phosphorylation GO:0042325 248 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
neuronal action potential GO:0019228 35 0.015
negative regulation of response to stimulus GO:0048585 155 0.014
sensory perception GO:0007600 101 0.014
aminoglycan biosynthetic process GO:0006023 4 0.014
regulation of b cell mediated immunity GO:0002712 2 0.014
response to interleukin 1 GO:0070555 55 0.014
endocytosis GO:0006897 84 0.014
ovulation cycle process GO:0022602 50 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
neuron differentiation GO:0030182 368 0.014
response to peptide hormone GO:0043434 278 0.014
positive regulation of b cell mediated immunity GO:0002714 2 0.014
mesonephric tubule development GO:0072164 14 0.014
regulation of body fluid levels GO:0050878 90 0.014
positive regulation of signaling GO:0023056 270 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
neuron projection development GO:0031175 273 0.014
cellular component biogenesis GO:0044085 368 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
positive regulation of protein modification process GO:0031401 142 0.013
salivary gland development GO:0007431 3 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
multicellular organismal signaling GO:0035637 44 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
regulation of mapk cascade GO:0043408 116 0.013
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.013
regulation of response to external stimulus GO:0032101 106 0.013
negative regulation of innate immune response GO:0045824 4 0.013
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.013
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.013
response to radiation GO:0009314 137 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
cellular response to lipid GO:0071396 201 0.013
regulation of hydrolase activity GO:0051336 143 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
nucleic acid templated transcription GO:0097659 379 0.013
muscle system process GO:0003012 115 0.013
ribose phosphate metabolic process GO:0019693 235 0.012
isopeptide cross linking GO:0018262 1 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
ras protein signal transduction GO:0007265 29 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
mirna metabolic process GO:0010586 1 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
positive regulation of molecular function GO:0044093 230 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
response to magnesium ion GO:0032026 20 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.012
mammary gland epithelium development GO:0061180 1 0.012
coagulation GO:0050817 28 0.012
vascular process in circulatory system GO:0003018 96 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
blood coagulation GO:0007596 26 0.012
development of primary sexual characteristics GO:0045137 107 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
gland development GO:0048732 155 0.012
rho protein signal transduction GO:0007266 11 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
dephosphorylation GO:0016311 98 0.012
aging GO:0007568 241 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of nervous system development GO:0051960 264 0.012
hemostasis GO:0007599 26 0.012
response to vitamin d GO:0033280 34 0.011
male gamete generation GO:0048232 99 0.011
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
response to lipopolysaccharide GO:0032496 191 0.011
blood circulation GO:0008015 183 0.011
regulation of epithelial cell migration GO:0010632 17 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
b cell activation involved in immune response GO:0002312 1 0.011
jak stat cascade GO:0007259 26 0.011
gastrulation GO:0007369 2 0.011
hematopoietic or lymphoid organ development GO:0048534 36 0.011
multicellular organism growth GO:0035264 1 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
response to ionizing radiation GO:0010212 59 0.011
germ cell migration GO:0008354 1 0.011
response to cytokine GO:0034097 215 0.011
regulation of smooth muscle cell migration GO:0014910 36 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of response to wounding GO:1903034 69 0.011
positive regulation of cell motility GO:2000147 97 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of blood pressure GO:0008217 83 0.011
response to molecule of bacterial origin GO:0002237 194 0.010
multicellular organism reproduction GO:0032504 233 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
regulation of blood vessel size GO:0050880 89 0.010
organic substance catabolic process GO:1901575 316 0.010
cell motility GO:0048870 202 0.010
sexual reproduction GO:0019953 148 0.010
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.010
positive regulation of cell development GO:0010720 176 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
regulation of secretion by cell GO:1903530 208 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
secretion by cell GO:0032940 248 0.010
response to acid chemical GO:0001101 222 0.010
gamete generation GO:0007276 124 0.010

Eng disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.077
musculoskeletal system disease DOID:17 0 0.077
hypertension DOID:10763 0 0.053
artery disease DOID:0050828 0 0.053
vascular disease DOID:178 0 0.053
essential hypertension DOID:10825 0 0.053
cardiovascular system disease DOID:1287 0 0.053
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.024
connective tissue disease DOID:65 0 0.015
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015
immune system disease DOID:2914 0 0.012
lymphatic system disease DOID:75 0 0.012
muscular dystrophy DOID:9884 0 0.012